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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Levomil 40mg Er Capsule is indicated for the treatment of major depressive disorder. It contains Levomilnacipran, which works by increasing the levels of natural substances in the brain, such as serotonin and norepinephrine, that help maintain mental balance. Thereby, it helps treat depression. Sometimes, Levomil 40mg Er Capsule may cause side effects such as nausea, vomiting, constipation, decreased appetite, and excessive sweating.

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Whats That

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Synonym :

LEVOMILNACIPRAN HYDROCHLORIDE

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Levomil 40mg Er Capsule

Levomil 40mg Er Capsule belongs to a group of medicines called selective serotonin and norepinephrine reuptake inhibitors (SNRIs) indicated for the treatment of major depressive disorder. Major depressive disorder is characterised by a persistent and intense feeling of sadness for an extended duration of time.

Levomil 40mg Er Capsule contains Levomilnacipran, which works by increasing the levels of natural substances in the brain, such as serotonin and norepinephrine, that help maintain mental balance. Thereby, it helps treat depression.

In some cases, Levomil 40mg Er Capsule may cause side effects such as nausea, vomiting, constipation, decreased appetite, and excessive sweating. Most of these side effects may not require medical attention and resolve gradually over time. However, if any of the side effects persist or worsen, consult the doctor.

Let the doctor know if you are allergic to any components in Levomil 40mg Er Capsule . Consult the doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Levomil 40mg Er Capsule

Levomil 40mg Er Capsule is used in the treatment of Major depressive disorder. The detailed use of Levomil 40mg Er Capsule is as follows:<br/>• Treatment of Major depressive disorder: Levomil 40mg Er Capsule helps to manage symptoms of Major Depressive Disorder (MDD), including feelings of sadness and loss of interest, by balancing brain chemicals like serotonin and norepinephrine to improve mood and reduce depression symptoms.<br/>

Directions for Use

• Take Levomil 40mg Er Capsule with or without food or as advised by a doctor.• Recommended to take once daily or as advised by your doctor.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Levomil 40mg Er Capsule belongs to a group of medicines called selective serotonin and norepinephrine reuptake inhibitors (SNRIs) indicated for the treatment of major depressive disorder. Levomil 40mg Er Capsule contains Levomilnacipran, which works by increasing the levels of natural substances in the brain, such as serotonin and norepinephrine, that help maintain mental balance. Thereby, it helps treat depression.

How Levomil 40mg Er Capsule Works

Levomil 40mg Er Capsule contains Levomilnacipran, which works by increasing the levels of natural substances in the brain, such as serotonin and norepinephrine, that help maintain mental balance. Thereby, it helps treat depression.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Levomil 40mg Er Capsule out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Levomil 40 ER Capsule
The following steps may be taken to support your person having suicidal behaviour:
  • Recognize the warning signs such as verbal and non-verbal communication, and personal behaviors. The risk increases in patients with depression or bipolar disorder.
  • Be there for them in person or by phone.
  • Encourage person to consult a mental health professional immediately.
  • Be non-judgemental and talk openly to them.
  • Show empathy and not sympathy.
  • Keep them safe by limiting access to lethal means.
Managing Medication-Triggered Urinary hesitancy (Difficulty passing urine): A Step-by-Step Guide:
  • Consult Your Doctor: If you experience urinary difficulties after taking medication, consult your doctor immediately and share your symptoms, medication regimen, and medical history.
  • Your doctor will assess your medication regimen to determine if it contributes to urinary hesitancy. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may recommend changes to your daily habits, such as drinking more water, limiting caffeine and alcohol, and exercising regularly. Additionally, your doctor may prescribe medications to help relax the muscles in the bladder and urethra, improve urine flow, or reduce symptoms.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.

What if I have taken an overdose of Levomil 40mg Er Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Levomil 40mg Er Capsule may include severe dizziness, confusion, increased heart rate, high blood pressure, and agitation. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Levomil 40mg Er Capsule if you are allergic to any of its components or if you take monoamine oxidase inhibitors (MAOI) or have taken them in the past 14 days. Inform the doctor if you have/had glaucoma, high blood pressure, heart problems, stroke, bleeding problems, sexual problems, seizures, low sodium levels, bipolar disorder, liver or kidney problems. Seek medical attention if you notice symptoms of serotonin syndrome (hallucination, agitation, sweating, shivering, fever, fast heart rate, twitching, nausea, vomiting, or loss of coordination), mood changes or if you have suicidal thoughts such as killing or harming yourself. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you are taking any other medicines, including herbal products and supplements.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Levomil 40 ER Capsule:
Taking Tranylcypromine with Levomil 40 ER Capsule can increases the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a of interaction between Levomil 40 ER Capsule and Tranylcypromine, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Levomil 40 ER Capsule:
Taking safinamide with Levomil 40 ER Capsule can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking safinamide with Levomil 40 ER Capsule is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Levomil 40 ER Capsule:
Using fluvoxamine together with Levomil 40 ER Capsule can increase the risk of serotonin syndrome(A condition in which a chemical called serotonin increase in your body)

How to manage the interaction:
Co-administration of Fluvoxamine with Levomil 40 ER Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms, stomach cramps, nausea, vomiting, and diarrhea contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Levomil 40 ER Capsule:
Co-administration of Itraconazole and Levomil 40 ER Capsule may raise the blood levels of Levomil 40 ER Capsule.

How to manage the interaction:
Itraconazole and Levomil 40 ER Capsule may interact, but if a doctor prescribes them, you can still use them. If you have any unexpected symptoms, including erectile dysfunction in men, constipation, rapid heartbeat, a racing heart, or nausea and vomiting, contact a doctor. Never discontinue taking a medication without consulting a doctor.
How does the drug interact with Levomil 40 ER Capsule:
When venlafaxine is taken with Levomil 40 ER Capsule, the risk of serotonin syndrome increases (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Venlafaxine and Levomil 40 ER Capsule, you can take these medicines together if prescribed by a doctor. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Levomil 40 ER Capsule:
Combining Sumatriptan with Levomil 40 ER Capsule might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Sumatriptan with Levomil 40 ER Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Levomil 40 ER Capsule:
Coadministration of Ketoconazole and Levomil 40 ER Capsule may enhance the blood levels and effects of Levomil 40 ER Capsule.

How to manage the interaction:
Taking Ketoconazole and Levomil 40 ER Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms or more frequent side effects, such as nausea, vomiting, constipation, a fast heartbeat, palpitations, or erectile problems in men consult a doctor. You might require more frequent blood pressure monitoring if you have high blood pressure. Avoid activities requiring mental alertness such as driving or operating machinery. Do not stop using any medications without a doctor's advice.
How does the drug interact with Levomil 40 ER Capsule:
Combining Levomil 40 ER Capsule with Amitriptyline can increase the risk of serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although using Levomil 40 ER Capsule and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Levomil 40 ER Capsule:
Co-administration of tramadol with Levomil 40 ER Capsule can increase the effect of tramadol.

How to manage the interaction:
Taking Levomil 40 ER Capsule with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintaining a healthy diet and exercising helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural anti-depressants. It also helps in relieving stress, improving mood, boosting self-esteem, and providing restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT
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Alcohol

Unsafe

Avoid consumption of alcohol while on treatment with Levomil 40mg Er Capsule .

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Pregnancy

Caution

Levomilnacipran belongs to pregnancy category C. It should be used during pregnancy only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if Levomilnacipran passes into breastmilk. Consult the doctor if you are breastfeeding.

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Driving

Caution

Levomil 40mg Er Capsule may cause drowsiness and affect your judgement, movements and thinking. Avoid driving or operating machinery unless you know how this medicine affects you.

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Liver

Consult your doctor

Please consult the doctor if you have liver problems before taking Levomil 40mg Er Capsule .

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Kidney

Caution

Levomil 40mg Er Capsule is not recommended for people with end-stage renal disease. Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Levomil 40mg Er Capsule is not recommended for children as the safety and effectiveness have not been established.

Have a query?

FAQs

Levomil 40mg Er Capsule is used to treat Major depressive disorder.

Levomil 40mg Er Capsule works by increasing the levels of natural substances in the brain, such as serotonin and norepinephrine, that help maintain mental balance.

Levomil 40mg Er Capsule may cause angle-closure glaucoma. Consult the doctor if you have eye pain, nausea, changes in vision, swelling or redness in or around the eye.

To treat your condition effectually, continue taking Levomil 40mg Er Capsule for as long as your doctor has prescribed. Speak with your doctor if you experience any difficulty while taking Levomil 40mg Er Capsule . Do not discontinue the medicine without consulting your doctor.

Levomil 40mg Er Capsule may cause high blood pressure. Therefore, inform the doctor if you have hypertension. Blood pressure and pulse/heart rate should be monitored prior to the start of the treatment and regularly during treatment with Levomil 40mg Er Capsule .

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - LEV0961

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