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compositionComposition:RABEPRAZOLE-20MG
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Prescription Medicine
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Libreb 20mg Injection belongs to the class of proton pump inhibitors. It is used in the treatment of Gastro-oesophageal reflux disease (GERD), duodenal/gastric ulcers, and Zollinger-Ellison syndrome. It contains rabeprazole, which help decrease the amount of acid in the stomach. Some of the common side effects include headache, diarrhoea, constipation, abdominal pain, flatulence, vomiting, nausea, etc.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

RABEPRAZOLE-20MG

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Libreb 20mg Injection

Libreb 20mg Injection is a prescription medication injected into a vein to treat conditions caused by excess stomach acid, such as severe gastroesophageal reflux disease (GERD) and stomach ulcers. It is typically prescribed when a patient is temporarily unable to take medications by mouth. This medicine helps heal damage to the food pipe (oesophagus) and stomach lining by significantly lowering daily acid production.

It is usually injected once daily by a healthcare professional, and maintaining a consistent schedule helps ensure its effectiveness. Because this medication is given directly into a vein, you do not need to worry about taking it with food. Making simple dietary changes, like avoiding spicy and highly acidic foods, can also help improve your overall recovery results.

While most people tolerate this medicine well, some may experience mild side effects like headaches or nausea. If you notice severe signs like persistent diarrhoea, muscle weakness, or a sudden allergic reaction, you must consult your doctor immediately.

Before starting this treatment, tell your healthcare provider if you have severe liver damage or low magnesium levels. Do not take this if you are allergic to similar acid-reducing medications.

This medicine can interact with certain blood thinners, antifungals, or HIV medications, which is why sharing your full medication list with your doctor is highly important. It is also wise to limit alcohol and avoid smoking, as both can worsen stomach irritation. If you are pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist to ensure this treatment is safe for you.

Uses of Libreb 20mg Injection

Libreb 20mg Injection may be used to help manage the following conditions:

  • Gastroesophageal Reflux Disease (GERD) with erosive oesophagitis: Libreb 20mg Injection helps heal the inflamed food pipe and relieves symptoms like chronic heartburn when oral treatment is not possible.
  • Stomach and Duodenal Ulcers: This medication reduces stomach acid to allow active sores in the stomach lining or the upper part of the small intestine to heal.
  • Zollinger-Ellison Syndrome: Libreb 20mg Injection manages this rare condition where the stomach produces extreme, harmful amounts of acid.
  • Prevention of Acid Aspiration: It can be used before certain surgeries to reduce the risk of stomach acid entering the lungs during anaesthesia.

Key Benefits

Libreb 20mg Injection injection is used for the short-term treatment of acid-related conditions when oral treatment is not suitable. It reduces stomach acid production, helping relieve symptoms and promote healing of acid-damaged tissues.

  • Provides Rapid Acid Control: Quickly reduces stomach acid production, helping relieve severe heartburn, acid reflux, and stomach discomfort.
  • Promotes Healing of Ulcers: Helps heal stomach and duodenal ulcers by reducing acid exposure and allowing damaged tissues to recover.
  • Protects the Oesophagus: Reduces acid-related injury to the food pipe, supporting healing in conditions such as gastro-oesophageal reflux disease (GERD).
  • Suitable When Oral Medicines Cannot Be Taken: Provides effective acid suppression for patients who are unable to swallow, are vomiting, or are recovering after surgery.
  • Helps Prevent Acid-Related Complications: By controlling stomach acid, it helps reduce the risk of complications such as ulcer progression and gastrointestinal bleeding.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Libreb 20mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Libreb 20mg Injection Works

Libreb 20mg Injection contains rabeprazole. It belongs to a group of medicines called proton pump inhibitors (PPIs). Inside the stomach wall, there are tiny cellular structures known as 'proton pumps' that actively produce and release stomach acid. When injected, the medicine travels through the bloodstream to target these pumps directly. It temporarily shuts down their acid-producing activity. By blocking the final step of acid secretion, Libreb 20mg Injection significantly lowers the acidity in your stomach, giving your digestive tract a safe environment to heal.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Libreb 20mg Injection. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will weigh the benefits and any potential risks before prescribing Libreb 20mg Injection.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Your doctor will decide if Libreb 20mg Injection can be taken by breastfeeding mothers or not.

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Driving

Caution

Libreb 20mg Injection may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Libreb 20mg Injection is not recommended for children as the safety and effectiveness were not established.

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Heart

Consult your doctor

Let your doctor know if you have any history of heart disease. Your doctor will weigh the benefits and potential risks before prescribing Libreb 20mg Injection.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Libreb 20mg Injection to geriatric patients. Your doctor will prescribe Libreb 20mg Injection if the benefits outweigh the risks.

What if I have taken an overdose of Libreb 20mg Injection

Since this medication is usually administered by medical professionals, an overdose is highly unlikely. However, if you suspect an overdose or experience severe symptoms like rapid heart rate or confusion, seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Avoid Trigger Foods: Limit foods and drinks that may worsen acid reflux, including spicy foods, citrus fruits, tomatoes, chocolate, caffeine, and high-fat meals.
  • Eat Smaller, Frequent Meals: Have smaller meals throughout the day instead of large meals to reduce stomach pressure.
  • Avoid Lying Down After Meals: Wait at least 2–3 hours after eating before lying down or going to bed.
  • Elevate the Head of Your Bed: Raise the head of your bed by 15–20 cm if you experience reflux symptoms at night.
  • Avoid Smoking and Limit Alcohol: Smoking and alcohol can worsen acid reflux and delay healing of the digestive tract.
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How Soon It Starts Working

The time required for Libreb 20mg Injection to start to work: The time required for Libreb 20mg Injection to show its action is unknown. The time for which the effects of Libreb 20mg Injection last: The duration of action for Libreb 20mg Injection is unknown.

What if you forget to take Libreb 20mg Injection

If you miss a scheduled injection, contact your doctor or healthcare provider immediately for instructions. Do not receive a double dose to make up for a missed one.

Storage

• Store the unmixed vial of Libreb 20mg Injection at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the Injection Before Use: Do not use the injection if the solution appears cloudy, discoloured, contains visible particles, or if the vial is damaged.
  • Rotate Injection Sites if Required: If repeated intravenous administration is needed, your healthcare provider may rotate injection sites to reduce the risk of vein irritation.
  • Use for the Recommended Duration: Libreb 20mg Injection injection is generally intended for short-term use. Consult your doctor if your symptoms do not improve or if prolonged treatment is required.
  • Inform Your Healthcare Provider Before Laboratory Tests: Tell your doctor or laboratory personnel that you are receiving Libreb 20mg Injection, as it may affect the results of certain diagnostic tests.
  • Attend Regular Monitoring if Used Long Term: If treatment continues for an extended period, your doctor may monitor your kidney function and blood magnesium levels periodically.

verifiedApollotooltip
  • Acid-Dependent Medicines: Libreb 20mg Injection may reduce the absorption and effectiveness of medicines that require stomach acid for absorption, such as ketoconazole, itraconazole, and atazanavir.
  • Warfarin: Concurrent use may increase the risk of bleeding. Your doctor may monitor your clotting parameters more closely.
  • Methotrexate: Libreb 20mg Injection may increase methotrexate levels in the body, raising the risk of toxicity, particularly with high-dose methotrexate therapy.

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verifiedApollotooltip
  • No clinically significant food interactions are known with Libreb 20mg Injection when used as directed.     
     

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Habit Forming

No

Therapeutic Class

[ANTIULCERANTS]

FAQs

Libreb 20mg Injection is used to treat gastric/duodenal ulcers, gastro-oesophageal reflux disease (GERD), heartburn, prevention of acid-aspiration, stress-induced mucosal injury, and Zollinger-Ellison syndrome.
Libreb 20mg Injection works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.
Diarrhoea might be a side-effect of Libreb 20mg Injection. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Prolonged intake of Libreb 20mg Injection is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.
Dry mouth could be a side-effect of Libreb 20mg Injection. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
On long-term treatment, Libreb 20mg Injection might increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis or if you are taking corticosteroids.
Libreb 20mg Injection may increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice any signs of increased bleeding or bruising.
Yes, but only if you have received comprehensive training from a healthcare professional on how to prepare and inject it safely. Otherwise, it should always be given by a nurse or doctor. Talk to your doctor.
The safety of this medicine during pregnancy or breastfeeding is not fully established. You should only use it if your doctor determines the benefits outweigh the risks. Talk to your doctor.
Mild redness can occur at the injection site. However, if the pain worsens, swells significantly, or feels hot to the touch, contact your healthcare provider right away. Talk to your doctor.
It is highly recommended to avoid alcohol while using this medicine. Alcohol can irritate your stomach lining and worsen the symptoms of reflux or ulcers, making the treatment less effective. Talk to your doctor.
When used for a short duration, serious long-term side effects are rare. However, extended use of acid reducers can lead to low magnesium levels, vitamin B12 deficiency, or weakened bones. Talk to your doctor.
No, you should never mix Libreb 20mg Injection with other drugs in the same syringe or infusion line unless specifically instructed by a healthcare professional, as it can cause dangerous chemical reactions. Talk to your doctor.
Most people do not experience side effects that impair their driving ability. However, if you feel dizzy or sleepy after receiving the injection, avoid driving or operating machinery. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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