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compositionComposition:RABEPRAZOLE-20MG
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RABICIP I.V INJECTION 5 ml belongs to the class of proton pump inhibitors. It is used in the treatment of Gastro-oesophageal reflux disease (GERD), duodenal/gastric ulcers, and Zollinger-Ellison syndrome. It contains rabeprazole, which help decrease the amount of acid in the stomach. Some of the common side effects include headache, diarrhoea, constipation, abdominal pain, flatulence, vomiting, nausea, etc.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

RABEPRAZOLE-20MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About RABICIP I.V INJECTION 5 ml

RABICIP I.V INJECTION 5 ml is a prescription medication injected into a vein to treat conditions caused by excess stomach acid, such as severe gastroesophageal reflux disease (GERD) and stomach ulcers. It is typically prescribed when a patient is temporarily unable to take medications by mouth. This medicine helps heal damage to the food pipe (oesophagus) and stomach lining by significantly lowering daily acid production.

It is usually injected once daily by a healthcare professional, and maintaining a consistent schedule helps ensure its effectiveness. Because this medication is given directly into a vein, you do not need to worry about taking it with food. Making simple dietary changes, like avoiding spicy and highly acidic foods, can also help improve your overall recovery results.

While most people tolerate this medicine well, some may experience mild side effects like headaches or nausea. If you notice severe signs like persistent diarrhoea, muscle weakness, or a sudden allergic reaction, you must consult your doctor immediately.

Before starting this treatment, tell your healthcare provider if you have severe liver damage or low magnesium levels. Do not take this if you are allergic to similar acid-reducing medications.

This medicine can interact with certain blood thinners, antifungals, or HIV medications, which is why sharing your full medication list with your doctor is highly important. It is also wise to limit alcohol and avoid smoking, as both can worsen stomach irritation. If you are pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist to ensure this treatment is safe for you.

Uses of RABICIP I.V INJECTION 5 ml

RABICIP I.V INJECTION 5 ml may be used to help manage the following conditions:

  • Gastroesophageal Reflux Disease (GERD) with erosive oesophagitis: RABICIP I.V INJECTION 5 ml helps heal the inflamed food pipe and relieves symptoms like chronic heartburn when oral treatment is not possible.
  • Stomach and Duodenal Ulcers: This medication reduces stomach acid to allow active sores in the stomach lining or the upper part of the small intestine to heal.
  • Zollinger-Ellison Syndrome: RABICIP I.V INJECTION 5 ml manages this rare condition where the stomach produces extreme, harmful amounts of acid.
  • Prevention of Acid Aspiration: It can be used before certain surgeries to reduce the risk of stomach acid entering the lungs during anaesthesia.

Key Benefits

RABICIP I.V INJECTION 5 ml injection is used for the short-term treatment of acid-related conditions when oral treatment is not suitable. It reduces stomach acid production, helping relieve symptoms and promote healing of acid-damaged tissues.

  • Provides Rapid Acid Control: Quickly reduces stomach acid production, helping relieve severe heartburn, acid reflux, and stomach discomfort.
  • Promotes Healing of Ulcers: Helps heal stomach and duodenal ulcers by reducing acid exposure and allowing damaged tissues to recover.
  • Protects the Oesophagus: Reduces acid-related injury to the food pipe, supporting healing in conditions such as gastro-oesophageal reflux disease (GERD).
  • Suitable When Oral Medicines Cannot Be Taken: Provides effective acid suppression for patients who are unable to swallow, are vomiting, or are recovering after surgery.
  • Helps Prevent Acid-Related Complications: By controlling stomach acid, it helps reduce the risk of complications such as ulcer progression and gastrointestinal bleeding.
Side effects of RABICIP I.V INJECTION 5 ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • RABICIP I.V INJECTION 5 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How RABICIP I.V INJECTION 5 ml Works

RABICIP I.V INJECTION 5 ml contains rabeprazole. It belongs to a group of medicines called proton pump inhibitors (PPIs). Inside the stomach wall, there are tiny cellular structures known as 'proton pumps' that actively produce and release stomach acid. When injected, the medicine travels through the bloodstream to target these pumps directly. It temporarily shuts down their acid-producing activity. By blocking the final step of acid secretion, RABICIP I.V INJECTION 5 ml significantly lowers the acidity in your stomach, giving your digestive tract a safe environment to heal.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking RABICIP I.V INJECTION 5 ml. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will weigh the benefits and any potential risks before prescribing RABICIP I.V INJECTION 5 ml.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Your doctor will decide if RABICIP I.V INJECTION 5 ml can be taken by breastfeeding mothers or not.

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Driving

Caution

RABICIP I.V INJECTION 5 ml may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

RABICIP I.V INJECTION 5 ml is not recommended for children as the safety and effectiveness were not established.

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Heart

Consult your doctor

Let your doctor know if you have any history of heart disease. Your doctor will weigh the benefits and potential risks before prescribing RABICIP I.V INJECTION 5 ml.

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Geriatrics

Consult your doctor

Please consult a doctor before administering RABICIP I.V INJECTION 5 ml to geriatric patients. Your doctor will prescribe RABICIP I.V INJECTION 5 ml if the benefits outweigh the risks.

What if I have taken an overdose of RABICIP I.V INJECTION 5 ml

Since this medication is usually administered by medical professionals, an overdose is highly unlikely. However, if you suspect an overdose or experience severe symptoms like rapid heart rate or confusion, seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Avoid Trigger Foods: Limit foods and drinks that may worsen acid reflux, including spicy foods, citrus fruits, tomatoes, chocolate, caffeine, and high-fat meals.
  • Eat Smaller, Frequent Meals: Have smaller meals throughout the day instead of large meals to reduce stomach pressure.
  • Avoid Lying Down After Meals: Wait at least 2–3 hours after eating before lying down or going to bed.
  • Elevate the Head of Your Bed: Raise the head of your bed by 15–20 cm if you experience reflux symptoms at night.
  • Avoid Smoking and Limit Alcohol: Smoking and alcohol can worsen acid reflux and delay healing of the digestive tract.
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How Soon It Starts Working

The time required for RABICIP I.V INJECTION 5 ml to start to work: The time required for RABICIP I.V INJECTION 5 ml to show its action is unknown. The time for which the effects of RABICIP I.V INJECTION 5 ml last: The duration of action for RABICIP I.V INJECTION 5 ml is unknown.

What if you forget to take RABICIP I.V INJECTION 5 ml

If you miss a scheduled injection, contact your doctor or healthcare provider immediately for instructions. Do not receive a double dose to make up for a missed one.

Storage

• Store the unmixed vial of RABICIP I.V INJECTION 5 ml at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the Injection Before Use: Do not use the injection if the solution appears cloudy, discoloured, contains visible particles, or if the vial is damaged.
  • Rotate Injection Sites if Required: If repeated intravenous administration is needed, your healthcare provider may rotate injection sites to reduce the risk of vein irritation.
  • Use for the Recommended Duration: RABICIP I.V INJECTION 5 ml injection is generally intended for short-term use. Consult your doctor if your symptoms do not improve or if prolonged treatment is required.
  • Inform Your Healthcare Provider Before Laboratory Tests: Tell your doctor or laboratory personnel that you are receiving RABICIP I.V INJECTION 5 ml, as it may affect the results of certain diagnostic tests.
  • Attend Regular Monitoring if Used Long Term: If treatment continues for an extended period, your doctor may monitor your kidney function and blood magnesium levels periodically.

Drug-Drug Interactions

verifiedApollotooltip
  • Acid-Dependent Medicines: RABICIP I.V INJECTION 5 ml may reduce the absorption and effectiveness of medicines that require stomach acid for absorption, such as ketoconazole, itraconazole, and atazanavir.
  • Warfarin: Concurrent use may increase the risk of bleeding. Your doctor may monitor your clotting parameters more closely.
  • Methotrexate: RABICIP I.V INJECTION 5 ml may increase methotrexate levels in the body, raising the risk of toxicity, particularly with high-dose methotrexate therapy.
RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical
How does the drug interact with RABICIP I.V INJECTION 5 ml:
Co-administration of RABICIP I.V INJECTION 5 ml can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking RABICIP I.V INJECTION 5 ml with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with RABICIP I.V INJECTION 5 ml:
When used in combination with erlotinib, RABICIP I.V INJECTION 5 ml may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking RABICIP I.V INJECTION 5 ml with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
How does the drug interact with RABICIP I.V INJECTION 5 ml:
Taking Clopidogrel with RABICIP I.V INJECTION 5 ml can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Clopidogrel and RABICIP I.V INJECTION 5 ml together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with RABICIP I.V INJECTION 5 ml:
Co-administration of Methotrexate with RABICIP I.V INJECTION 5 ml can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between RABICIP I.V INJECTION 5 ml and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with RABICIP I.V INJECTION 5 ml:
When Phenytoin and RABICIP I.V INJECTION 5 ml are taken in combination, Phenytoin will reduce the concentration or impact of RABICIP I.V INJECTION 5 ml.

How to manage the interaction:
Although taking Phenytoin and RABICIP I.V INJECTION 5 ml together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleIdelalisib
Severe
How does the drug interact with RABICIP I.V INJECTION 5 ml:
When RABICIP I.V INJECTION 5 ml and Idelalisib are taken in combination, Idelalisib may increase the level or impact of RABICIP I.V INJECTION 5 ml.

How to manage the interaction:
Although taking RABICIP I.V INJECTION 5 ml and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with RABICIP I.V INJECTION 5 ml:
Co-administration of Atazanavir's blood levels and absorption can both be affected by RABICIP I.V INJECTION 5 ml, which decreases the atazanavir's ability to treat HIV.

How to manage the interaction:
Although taking RABICIP I.V INJECTION 5 ml and atazanavir together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with RABICIP I.V INJECTION 5 ml:
Taking RABICIP I.V INJECTION 5 ml together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking RABICIP I.V INJECTION 5 ml and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after RABICIP I.V INJECTION 5 ml. Do not discontinue any medications without a doctor's advice.
How does the drug interact with RABICIP I.V INJECTION 5 ml:
Taking RABICIP I.V INJECTION 5 ml together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking RABICIP I.V INJECTION 5 ml and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with RABICIP I.V INJECTION 5 ml:
Taking RABICIP I.V INJECTION 5 ml together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking RABICIP I.V INJECTION 5 ml and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with RABICIP I.V INJECTION 5 ml when used as directed.     
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIULCERANTS]

FAQs

RABICIP I.V INJECTION 5 ml is used to treat gastric/duodenal ulcers, gastro-oesophageal reflux disease (GERD), heartburn, prevention of acid-aspiration, stress-induced mucosal injury, and Zollinger-Ellison syndrome.
RABICIP I.V INJECTION 5 ml works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.
Diarrhoea might be a side-effect of RABICIP I.V INJECTION 5 ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Prolonged intake of RABICIP I.V INJECTION 5 ml is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.
Dry mouth could be a side-effect of RABICIP I.V INJECTION 5 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
On long-term treatment, RABICIP I.V INJECTION 5 ml might increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis or if you are taking corticosteroids.
RABICIP I.V INJECTION 5 ml may increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice any signs of increased bleeding or bruising.
Yes, but only if you have received comprehensive training from a healthcare professional on how to prepare and inject it safely. Otherwise, it should always be given by a nurse or doctor. Talk to your doctor.
The safety of this medicine during pregnancy or breastfeeding is not fully established. You should only use it if your doctor determines the benefits outweigh the risks. Talk to your doctor.
Mild redness can occur at the injection site. However, if the pain worsens, swells significantly, or feels hot to the touch, contact your healthcare provider right away. Talk to your doctor.
It is highly recommended to avoid alcohol while using this medicine. Alcohol can irritate your stomach lining and worsen the symptoms of reflux or ulcers, making the treatment less effective. Talk to your doctor.
When used for a short duration, serious long-term side effects are rare. However, extended use of acid reducers can lead to low magnesium levels, vitamin B12 deficiency, or weakened bones. Talk to your doctor.
No, you should never mix RABICIP I.V INJECTION 5 ml with other drugs in the same syringe or infusion line unless specifically instructed by a healthcare professional, as it can cause dangerous chemical reactions. Talk to your doctor.
Most people do not experience side effects that impair their driving ability. However, if you feel dizzy or sleepy after receiving the injection, avoid driving or operating machinery. Talk to your doctor.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - RAB0089
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