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compositionComposition:LINEZOLID-200MG
prescription
Prescription Medicine
info
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Lincef Novo IV 600 mg Infusion 300 ml is an antibiotic medication used to treat bacterial infections of the skin and soft tissues, lungs (pneumonia) and bloodstream infections. It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LINEZOLID-200MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Lincef Novo IV 600 mg Infusion 300 ml

Lincef Novo IV 600 mg Infusion 300 ml is a sterile injection used to treat serious bacterial infections, including certain types of pneumonia and severe skin infections. It belongs to a class of antibiotics that stop the growth of bacteria, helping your body fight off the infection. Doctors reserve this medicine for complicated infections, especially those resistant to other antibiotics.

Because this medicine is given directly into a vein, healthcare professionals usually give it at regular intervals to maintain a steady level in your blood. You do not need to worry about taking it with food, as the injection bypasses the stomach. Eating a balanced diet and staying well-hydrated can support your immune system during treatment.

While using Lincef Novo IV 600 mg Infusion 300 ml, you may experience mild side effects like diarrhoea, headaches, or nausea. However, you must contact your healthcare provider immediately if you experience severe symptoms such as blurred vision, persistent diarrhoea, or unusual bruising.

Talk to your doctor before starting this medicine if you have high blood pressure, thyroid problems, or a history of seizures. Do not take this if you are currently taking, or have taken in the last two weeks, a monoamine oxidase inhibitor (MAOI) for depression.

Lincef Novo IV 600 mg Infusion 300 ml can interact with certain foods containing tyramine (like aged cheeses) and medicines that increase serotonin levels, which can cause a dangerous rise in blood pressure. It is also important to avoid alcohol during treatment, and you should consult your doctor if you are pregnant, breastfeeding, or an older adult.
 

Uses of Lincef Novo IV 600 mg Infusion 300 ml

Lincef Novo IV 600 mg Infusion 300 ml is used to treat serious bacterial infections. The detailed uses of Lincef Novo IV 600 mg Infusion 300 ml are as follows:

  • Pneumonia: Lincef Novo IV 600 mg Infusion 300 ml helps clear severe lung infections, including hospital-acquired and community-acquired pneumonia caused by susceptible bacteria.
  • Complicated skin and soft tissue infections: Lincef Novo IV 600 mg Infusion 300 ml targets and eliminates bacteria causing deep skin infections, helping the tissue heal properly.
  • Vancomycin-resistant Enterococcus (VRE) infections: Lincef Novo IV 600 mg Infusion 300 ml is highly effective against specific drug-resistant bacterial strains that other antibiotics cannot treat.
     

Key Benefits

Lincef Novo IV 600 mg Infusion 300 ml provides critical therapeutic benefits for patients facing hard-to-treat bacterial infections:

  • Targeted treatment of resistant bacteria: It overcomes bacterial resistance, giving patients a reliable treatment option when standard antibiotics fail.
  • Faster recovery from severe illness: By rapidly stopping bacterial growth, it helps reduce fever, chest discomfort, and skin inflammation, allowing you to regain your strength sooner.
  • Direct delivery into the bloodstream: The parenteral route ensures 100% of the medication is immediately available to fight infection throughout the body.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Lincef Novo IV 600 mg Infusion 300 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Lincef Novo IV 600 mg Infusion 300 ml Works

Lincef Novo IV 600 mg Infusion 300 ml contains linezolid, which works by stopping bacteria from growing and multiplying. It does this by binding to a specific part of the bacterial cell (the ribosome) and preventing it from making essential proteins that the bacteria need to survive and replicate. Without these vital proteins, the bacteria cannot spread or maintain their structure. This stops the infection in its tracks, allowing your body's natural immune system to easily target and clear the remaining bacteria.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Lincef Novo IV 600 mg Infusion 300 ml as it may cause increased dizziness.

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Pregnancy

Consult your doctor

The safety of Lincef Novo IV 600 mg Infusion 300 ml in pregnant women is not known. If you are pregnant, consult your doctor.

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Breast Feeding

Caution

If you are a breastfeeding mother, inform your doctor before receiving this medicine. Lincef Novo IV 600 mg Infusion 300 ml passes into breastmilk and can cause diarrhoea and vomiting in infants; therefore, discontinue breastfeeding prior to and throughout the treatment.

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Driving

Caution

Lincef Novo IV 600 mg Infusion 300 ml may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Long-term treatment with Lincef Novo IV 600 mg Infusion 300 ml may worsen your liver condition if you have liver problems. Dose adjustment may be needed. Please inform your doctor before taking Lincef Novo IV 600 mg Infusion 300 ml if you have liver impairment/liver disease or a history of liver conditions.

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Kidney

Consult your doctor

If you have kidney problems, inform your doctor before receiving this injection.

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Children

Consult your doctor

Your doctor will weigh the benefits and potential risks before prescribing Lincef Novo IV 600 mg Infusion 300 ml for your children based on age and the condition of the child.

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Heart

Caution

Lincef Novo IV 600 mg Infusion 300 ml can be used in heart patients but requires caution due to potential blood pressure changes. Always inform your doctor about your heart condition and medications to avoid serious interactions.

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Geriatrics

Caution

Geriatric patients can receive Lincef Novo IV 600 mg Infusion 300 ml, but it may be more prone to side effects like low blood cell counts or neuropathy. Regular monitoring and dose adjustments help ensure safe and effective treatment.

What if I have taken an overdose of Lincef Novo IV 600 mg Infusion 300 ml

If you receive too much of this medicine, or experience severe dizziness, vomiting, or muscle tremors, seek emergency medical care immediately.

Diet & Lifestyle Advise

  • Avoid foods high in tyramine: While using Lincef Novo IV 600 mg Infusion 300 ml, avoid aged cheeses, air-dried or cured meats, red wine, tap beers, sauerkraut, and soy sauce. These foods can react with the medicine and cause a dangerous spike in your blood pressure.
  • Stay hydrated: Drink plenty of water throughout your treatment to help your kidneys process the medication and to prevent dehydration, especially if you experience mild diarrhoea.
  • Limit caffeine intake: High amounts of caffeine from coffee, tea, energy drinks, or chocolate can increase the risk of elevated blood pressure when combined with this medicine.
  • Get plenty of rest: Your body needs energy to fight off a serious infection, so prioritise sleep and avoid strenuous physical activities during your recovery.
     
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How Soon It Starts Working

  • The time required for Lincef Novo IV 600 mg Infusion 300 ml to start to work: Lincef Novo IV 600 mg Infusion 300 ml ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of Lincef Novo IV 600 mg Infusion 300 ml last: The effect of Lincef Novo IV 600 mg Infusion 300 ml lasts for 12 hours.

What if you forget to take Lincef Novo IV 600 mg Infusion 300 ml

Since Lincef Novo IV 600 mg Infusion 300 ml is usually given by a healthcare provider, a missed dose is unlikely. If you are injecting it at home and miss a scheduled infusion, contact your doctor or nurse immediately for guidance. Do not double the dose to make up for a missed one.

Storage

• Store Lincef Novo IV 600 mg Infusion 300 ml infusion bags at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the solution before use: Always check the infusion bag for leaks, cloudiness, or floating particles. If you notice any of these, do not inject it and contact your pharmacist.
  • Monitor your blood counts: If you use this medicine for more than two weeks, your doctor will likely order weekly blood tests to check your platelet and red blood cell levels.
  • Check your vision: Tell your doctor immediately if you experience any changes in your eyesight, especially if your treatment lasts longer than 28 days.
  • Watch for nerve symptoms: Report any numbness, tingling, or weakness in your hands or feet, as these can be signs of nerve damage.
  • Rotate injection sites: If you are injecting this at home, rotate the injection site as directed by your nurse to prevent irritation or vein inflammation.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Antidepressants (such as SSRIs, SNRIs, and MAOIs): Combining these with Lincef Novo IV 600 mg Infusion 300 ml can lead to a life-threatening condition called serotonin syndrome, causing confusion, high fever, and muscle stiffness.
  • Decongestants and cold medicines: Medications containing pseudoephedrine or phenylephrine can cause a severe, sudden increase in blood pressure when taken with Lincef Novo IV 600 mg Infusion 300 ml.
  • Migraine medications (triptans): These can also increase the risk of serotonin syndrome.
     
LinezolidSertraline
Critical
LinezolidOxcarbazepine
Critical

Drug-Drug Interactions

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LinezolidSertraline
Critical
How does the drug interact with Lincef Novo IV 600 mg Infusion 300 ml:
When Lincef Novo IV 600 mg Infusion 300 ml is taken with Sertraline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
taking Lincef Novo IV 600 mg Infusion 300 ml and Sertraline is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhoea-contact a doctor right away. Do not stop using any medications without a doctor's advice.
LinezolidOxcarbazepine
Critical
How does the drug interact with Lincef Novo IV 600 mg Infusion 300 ml:
When Oxcarbazepine is taken with Lincef Novo IV 600 mg Infusion 300 ml, it can increase the risk of serotonin syndrome(a condition when your body has too much of a chemical called serotonin), further leading to side effects.

How to manage the interaction:
Taking Oxcarbazepine with Lincef Novo IV 600 mg Infusion 300 ml is not recommended, as it results in an interaction, it can be taken if advised by a doctor. However, if you experience symptoms such as confusion, hallucination (seeing or hearing things that do not exist), seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor’s advice.
LinezolidNortriptyline
Critical
How does the drug interact with Lincef Novo IV 600 mg Infusion 300 ml:
Coadministration of Nortriptyline with Lincef Novo IV 600 mg Infusion 300 ml might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Nortriptyline with Lincef Novo IV 600 mg Infusion 300 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LinezolidAmitriptyline
Critical
How does the drug interact with Lincef Novo IV 600 mg Infusion 300 ml:
Taking Lincef Novo IV 600 mg Infusion 300 ml with Amitriptyline can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Lincef Novo IV 600 mg Infusion 300 ml and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
LinezolidMethylphenidate
Critical
How does the drug interact with Lincef Novo IV 600 mg Infusion 300 ml:
Taking Lincef Novo IV 600 mg Infusion 300 ml with Methylphenidate together may increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Lincef Novo IV 600 mg Infusion 300 ml with Methylphenidate is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden and severe headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, contact a doctor immediately. You may use methylphenidate only after you have been off Lincef Novo IV 600 mg Infusion 300 ml for at least 14 days. Do not discontinue any medications without consulting a doctor.
LinezolidAtomoxetine
Critical
How does the drug interact with Lincef Novo IV 600 mg Infusion 300 ml:
Using Lincef Novo IV 600 mg Infusion 300 ml together with atomoxetine can cause high blood pressure.

How to manage the interaction:
Taking Lincef Novo IV 600 mg Infusion 300 ml with Atomoxetine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not stop using any medications without talking to a doctor.
LinezolidMephentermine
Critical
How does the drug interact with Lincef Novo IV 600 mg Infusion 300 ml:
Taking Lincef Novo IV 600 mg Infusion 300 ml and Mephentermine together may cause high blood pressure.

How to manage the interaction:
Taking Mephentermine with Lincef Novo IV 600 mg Infusion 300 ml is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LinezolidFentanyl
Critical
How does the drug interact with Lincef Novo IV 600 mg Infusion 300 ml:
Taking Lincef Novo IV 600 mg Infusion 300 ml with Fentanyl may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Lincef Novo IV 600 mg Infusion 300 ml and Fentanyl, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
LinezolidCarbamazepine
Critical
How does the drug interact with Lincef Novo IV 600 mg Infusion 300 ml:
Using Carbamazepine with Lincef Novo IV 600 mg Infusion 300 ml can cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Carbamazepine and Lincef Novo IV 600 mg Infusion 300 ml together is not recommended, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
LinezolidBuspirone
Critical
How does the drug interact with Lincef Novo IV 600 mg Infusion 300 ml:
Combining Lincef Novo IV 600 mg Infusion 300 ml with Buspirone can increase the risk of high blood pressure.

How to manage the interaction:
Taking Buspirone with Lincef Novo IV 600 mg Infusion 300 ml is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice

Drug-Food Interactions

verifiedApollotooltip
  • Tyramine-rich foods: Foods like aged cheese, smoked meats, yeast extracts, and draft beer can cause a dangerous rise in blood pressure.

 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Lincef Novo IV 600 mg Infusion 300 ml belongs to the class of medicines called oxazolidinones, used to treat bacterial infections of the lungs (pneumonia) and skin. It is also used to treat infections which are resistant to other antibiotics.
Lincef Novo IV 600 mg Infusion 300 ml works by stopping the growth of infection-causing bacteria. Thus, it treats the infection.
Diarrhoea might be a side-effect of Lincef Novo IV 600 mg Infusion 300 ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have prolonged diarrhoea with abdominal pain while on treatment with Lincef Novo IV 600 mg Infusion 300 ml, inform your doctor. Do not take anti-diarrheal medicine on your own.
Lincef Novo IV 600 mg Infusion 300 ml may cause oral or vaginal thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth/throat or vagina. Consult your doctor if the condition persists or worsens.
Lincef Novo IV 600 mg Infusion 300 ml may affect certain laboratory test results such as blood tests, blood sugar tests, and liver and kidney function tests. Inform the lab technician that you are on treatment with Lincef Novo IV 600 mg Infusion 300 ml.
Lincef Novo IV 600 mg Infusion 300 ml may cause anaemia due to a decrease in the number of red blood cells. This could also cause unexplained bleeding or bruising. Consult your doctor if you experience unexplained bleeding or bruising.
Lincef Novo IV 600 mg Infusion 300 ml may cause side effects, such as headache, a metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, pain at the injection site, and indigestion. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.
Your doctor may order weekly blood tests, especially if you are on this medicine for more than 10 to 14 days, to monitor your blood cell counts, as this medicine can temporarily lower them. Talk to your doctor if you have concerns about these tests.
No, you should avoid alcohol, especially draft beers and red wine, because they contain high levels of tyramine, which can cause a severe increase in your blood pressure when combined with this medicine. Talk to your doctor for more safety advice.
If you notice redness, swelling, pain, or warmth around the injection site, contact your healthcare provider right away, as these could be signs of skin irritation or infection. Talk to your doctor or nurse for proper care steps.
Yes, long-term use of Lincef Novo IV 600 mg Infusion 300 ml (usually more than 28 days) has been linked to nerve problems, such as numbness or tingling in the hands and feet. Talk to your doctor immediately if you experience these symptoms.
Yes, you must avoid foods rich in tyramine, such as aged cheeses, cured meats, and soy sauce, to prevent a dangerous rise in blood pressure. Talk to your doctor or pharmacist for a complete list of foods to avoid.
No, Lincef Novo IV 600 mg Infusion 300 ml is an antibiotic and only works against bacterial infections. It will not treat viral infections like the common cold or flu. Talk to your doctor to get an accurate diagnosis for your symptoms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.2931 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 021130S028Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Linezolid Injection Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. ScienceDirect ScienceDirect. [Accessed on 30 Mar. 2019]Check here
  5. Linezolid Linezolid. 2000. [Accessed on 30 Mar. 2019]Check here
  6. Linezolid 600 mg Tablet- Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 29 Dec 2025]Check here
  7. Linezolid 600 mg Tablet- Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 29 Dec 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - LIN0354
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