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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Liofen 10 Tablet is used to reduce and relieve muscle spasms (excessive tension in the muscles) occurring in various illnesses. It contains Baclofen, which works on the spinal cord and brain, thereby helping in maintaining muscle strength and relieving muscle spasms or stiffness. Thus, it reduces muscle spasm in the conditions of multiple sclerosis (a disorder which affects the brain and spinal cord), cerebrovascular accidents (damage to the brain due to lack of blood supply), cerebral palsy (a disorder of movement, posture and muscle tone), spinal cord diseases and other nervous system disorders. In some cases, you may experience certain common side effects such as sleepiness, drowsiness, nausea, headache, weakness, and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

BACLOFEN-10MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Liofen 10 Tablet

Liofen 10 Tablet is used to reduce and relieve muscle spasms (excessive tension in the muscles) occurring in various illnesses. Muscle spasm is the sudden involuntary contraction of a muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

Liofen 10 Tablet works on the spinal cord and brain, thereby helping in maintaining muscle strength and relieving muscle spasms or stiffness. Thus Liofen 10 Tablet reduces muscle spasm in the conditions of multiple sclerosis (a disorder which affects the brain and spinal cord), cerebrovascular accidents (damage to the brain due to lack of blood supply), cerebral palsy (a disorder of movement, posture and muscle tone), spinal cord diseases and other nervous system disorders.

Take Liofen 10 Tablet with food. You are advised to take Liofen 10 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as sleepiness, drowsiness, nausea, headache, weakness, and dry mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not discontinue Liofen 10 Tablet suddenly as it could lead to unpleasant side-effects such as rigidity, increased heart rate, changes in mood, fever, mental disorders, confusion, hallucinations, and fits (seizures). Consult your doctor before taking Liofen 10 Tablet if you are pregnant or breastfeeding. Liofen 10 Tablet should be given with caution in children below 16 years, as limited data is available on its safety and effectiveness. Liofen 10 Tablet is not recommended for children who weigh below 33 kg. Inform your doctor about all the current medicines you are taking and about your health condition to rule out any unpleasant side effects. Please speak to your doctor immediately if you experience mood swings or depression or if you have any suicidal thoughts.

Uses of Liofen 10 Tablet

Liofen 10 Tablet is used to reduce and relieve muscle stiffness and spasms. The detailed uses of Liofen 10 Tablet are as follows: <br/> • Treatment of muscle spasms in cerebral palsy: Reduces excessive muscle tension and improves mobility.<br/> • Management of spasticity in multiple sclerosis: Relieves painful muscle stiffness and improves daily function.<br/> • Relief after cerebrovascular accidents (stroke): Reduces involuntary muscle spasms and improves limb mobility.<br/> • Treatment of muscle tightness due to spinal cord diseases: Reduces muscle rigidity caused by spinal cord injuries or disorders.<br/> • Support in other nervous system disorders: Provides relief from abnormal muscle tone caused by various neurological conditions.<br/>

Directions for Use

  • Liofen 10 Tablet can be taken with food or as directed by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Liofen 10 Tablet as a whole with a glass of water.
  • Do not break, crush or chew it.

Medicinal Benefits

Liofen 10 Tablet belongs to the group of medicines called muscle relaxants used to reduce and relieve the muscle spasms (excessive tension in the muscles) occurring in various illnesses such as multiple sclerosis (a disorder which affects the brain and spinal cord), cerebrovascular accidents (damage to the brain due to lack of blood supply), cerebral palsy (a disorder of movement, posture and muscle tone), spinal cord diseases and other nervous system disorders. Liofen 10 Tablet works by inhibiting the reflexes at the spinal level, helps in relieving pain and improves muscle movements.

How Liofen 10 Tablet Works

Liofen 10 Tablet works on the spinal cord and brain, thereby helping in maintaining muscle strength and relieving muscle spasms or stiffness. Thus Liofen 10 Tablet reduces muscle spasm in the conditions of multiple sclerosis (a disorder which affects the brain and spinal cord), cerebrovascular accidents (damage to the brain due to lack of blood supply), cerebral palsy (a disorder of movement, posture and muscle tone), spinal cord diseases and other nervous system disorders.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Liofen 10 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Do pelvic floor exercises (Kegel exercises) to gain more control over urinary sphincters (muscles used to control flow of urine out of the bladder).
  • Drink fluids only at certain times to control when you will urinate.
  • If you feel frequent urge to urinate or have problems starting to urinate or if your urine stream is weak or starts and stops, or feel pain in your genitals, lower abdomen or lower back, consult your doctor.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Liofen 10 Tablet

Do not take more than the prescribed dose of Liofen 10 Tablet as it may cause an overdose. The symptoms of overdose include dizziness, drowsiness, seizures (fits), excess sleepiness, shallow breathing, trouble focusing on objects, loss of consciousness or muscle weakness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Liofen 10 Tablet if you are allergic to any of its contents or if you have ever had a stomach ulcer. Talk to your doctor before taking Liofen 10 Tablet if you have kidney or liver problems, mental disorders, breathing difficulty or lung disease, diabetes, difficulty in urination, high blood pressure, Parkinson’s disease, or if you have ever had a stroke. Consult your doctor before taking Liofen 10 Tablet if you are pregnant or breastfeeding. Liofen 10 Tablet should be given with caution in children below 16 years, as limited data is available on its safety and effectiveness. Liofen 10 Tablet is not recommended for children who weigh below 33 kg.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Liofen 10 Tablet:
Co-administration of fentanyl and Liofen 10 Tablet can increase sedation and may lead to respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although taking fentanyl and Liofen 10 Tablet together can result in an interaction, they can be taken if prescribed by a doctor. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Liofen 10 Tablet:
Co-administration of Liofen 10 Tablet can enhance the sedative effects of Pentazocine on the central nervous system which can lead to side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Liofen 10 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
BaclofenMethadone
Severe
How does the drug interact with Liofen 10 Tablet:
Co-administration of Liofen 10 Tablet with Methadone may cause serious side effects such as central nervous system depression can lead to serious side effects including respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Liofen 10 Tablet can be used with Methadone if prescribed by the doctor. Inform the prescriber if you are taking these two medicines, the doctor may prescribe alternate medicines a dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue any medications without consulting a doctor.
BaclofenRemifentanil
Severe
How does the drug interact with Liofen 10 Tablet:
Co-administration of Liofen 10 Tablet can enhance the sedative effects of Remifentanil on the central nervous system which can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Co-administration of Liofen 10 Tablet with Remifentanil can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend other options that won't cause any problems. If you notice any symptoms like feeling tired, dizzy, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
BaclofenPethidine
Severe
How does the drug interact with Liofen 10 Tablet:
Co-administration of Liofen 10 Tablet can enhance the sedative effects of Meperidine on the central nervous system which can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Pethidine with Liofen 10 Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
How does the drug interact with Liofen 10 Tablet:
Co-administration of Liofen 10 Tablet with Morphine may increase the risk or severity of side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Liofen 10 Tablet with Morphine together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you notice any sudden dizziness, lightheadedness, severe headache, shortness of breath, chest pain or tightness, or weakness. Do not stop using any medications without consulting a doctor.
How does the drug interact with Liofen 10 Tablet:
Co-administration of Liofen 10 Tablet with Tramadol may significantly lead to adverse effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although taking Liofen 10 Tablet and tramadol together can result in an interaction, it can be taken on a doctor's advice. If you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
BaclofenOxycodone
Severe
How does the drug interact with Liofen 10 Tablet:
Co-administration of Liofen 10 Tablet can enhance the sedative effects of Oxycodone on the central nervous system and can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is a possible interaction between Oxycodone and Liofen 10 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without first talking to your doctor.
BaclofenHydrocodone
Severe
How does the drug interact with Liofen 10 Tablet:
Co-administration of Liofen 10 Tablet with Hydrocodone may increase sedation and respiratory distress (fluid collects in the air sacs of the lungs)

How to manage the interaction:
Although there is an interaction, Liofen 10 Tablet can be used with Hydrocodone if prescribed by the doctor. Co-administration of these medications may cause dizziness, drowsiness, difficulty in concentrating, and impaired judgment. Do not stop any medication without doctor's consultation.
BaclofenDezocine
Severe
How does the drug interact with Liofen 10 Tablet:
Co-administration of Liofen 10 Tablet with Dezocine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Liofen 10 Tablet can be used with Dezocine if prescribed by the doctor. These may cause dizziness, drowsiness, palpitations, or chest discomfort. Do not stop taking the medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear, or sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid extremely cold and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can be helpful in treating muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

SKELETAL MUSCLE RELAXANTS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Liofen 10 Tablet as it may increase drowsiness.

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Pregnancy

Caution

Avoid taking Liofen 10 Tablet if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Liofen 10 Tablet ; your doctor will decide whether Liofen 10 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Liofen 10 Tablet causes sleepiness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Liofen 10 Tablet should be given with caution in children below 16 years, as limited data is available on its safety and effectiveness. Liofen 10 Tablet is not recommended for children who weigh below 33 kg.

Have a query?

FAQs

Liofen 10 Tablet is used to reduce and relieve excessive muscle stiffness or spasms associated with conditions like cerebral palsy, multiple sclerosis, stroke, spinal cord disorders, and other nervous system diseases.

Liofen 10 Tablet works on the centres of the spinal cord and brain, thereby helping in maintaining muscle strength and relieving muscle spasms or stiffness.

Liofen 10 Tablet causes sleepiness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel sleepy or drowsy.

Dry mouth could be a side-effect of Liofen 10 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevent drying of the mouth.

Do not discontinue Liofen 10 Tablet without consulting your doctor. Discontinuing Liofen 10 Tablet suddenly might cause muscle rigidity, increased heart rate, changes in mood, fever, mental disorders, confusion, hallucinations, and fits (seizures). Talk to your doctor if you feel any difficulty while taking Liofen 10 Tablet ; your doctor will reduce the dose gradually.

Do not use Liofen 10 Tablet at a time when muscle tone is required for safe balance and movement during certain activities. In some conditions, it may be dangerous for you to have low or reduced muscle tone. Please do not drink alcohol with Liofen 10 Tablet as it can cause side effects. Avoid driving or performing hazardous tasks until you know how Liofen 10 Tablet will affect you.

Liofen 10 Tablet may reduce anxiety but not depression levels. However, it is not intended for treating anxiety.

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

While specific dosing instructions will vary depending on your needs and medical history, always follow your doctor's prescribed dosage and timing for taking these medications.

To avoid potential interactions and minimise side effects, before using this medication, you should inform your doctor about your medical history, including any ongoing medicines.

Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Taking more than the recommended dosage does not provide additional benefits and can increase the risk of adverse effects. Take it only as advised by the doctor.

Liofen 10 Tablet does not affect any method of contraception, including combined tablets or emergency contraception. However, if baclofen makes you sick (vomit) or causes severe diarrhoea for more than 24 hours, your contraceptive tablets may not be effective in preventing pregnancy. Check the pill packet to see what to do.

Alcohol can increase the drowsy (sedative) effects of baclofen pills, making you extremely tired. It is advisable to avoid drinking alcohol when taking baclofen until you know how the medication affects you.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - LIO0001

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