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compositionComposition:LITHIUM CARBONATE-450MG
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Prescription Medicine
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Lithowel 450mg Tablet CR belongs to the class of antipsychotic medicine used in the treatment of bipolar disorder and mania. This medicine suppresses the excess and abnormal activity of nerve cells in the brain by increasing the activity of chemical messengers in the brain. Common side effects include loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

LITHIUM CARBONATE-450MG

Manufacturer/Marketer :

Sigmund Promedica

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Lithowel 450mg Tablet CR

Lithowel 450mg Tablet CR is a medication primarily prescribed to stabilise mood and treat manic episodes associated with bipolar disorder. It helps prevent and control severe mood swings, bringing emotional balance to those experiencing extreme highs and lows. This medicine plays a crucial role in long-term mental health management.

To get the best results, you must take Lithowel 450mg Tablet CR consistently at the same times every day as directed by your doctor. You can take this medication with or without food, though taking it with a meal can help prevent a mild upset stomach. Maintaining a highly consistent daily intake of fluids and dietary salt is also vital, as sudden changes can affect how your body handles the medicine.

While taking Lithowel 450mg Tablet CR, you may experience mild side effects like a slight hand tremor, increased thirst, or urinating more often. However, you must contact your doctor immediately if you experience severe hand shaking, persistent vomiting, severe diarrhoea, or slurred speech, as these can be signs of the medicine reaching unsafe levels in your blood.

Talk to your doctor before taking Lithowel 450mg Tablet CR if you have kidney disease, heart problems, thyroid issues, or if you are severely dehydrated. Do not take this if you have severe kidney failure, severe cardiovascular disease, untreated underactive thyroid, or severe dehydration, as the medicine can build up to dangerous levels in your body.

This medicine can interact with several other drugs, including common over-the-counter pain relievers, water pills, and certain blood pressure medicines, which can raise the amount of Lithowel 450mg Tablet CR in your blood and lead to side effects. You should also avoid alcohol, as it can worsen drowsiness and cause dehydration. If you are pregnant, breastfeeding, or an older adult, consult your doctor before starting Lithowel 450mg Tablet CR to discuss safe options.

Uses of Lithowel 450mg Tablet CR

Lithowel 450mg Tablet CR helps stabilise mood and manage certain mental health conditions. Your doctor may prescribe it for the following conditions:

  • Bipolar disorder: It acts as a long-term mood stabiliser to prevent and reduce the frequency and severity of manic (extreme highs) and depressive (extreme lows) episodes.
  • Acute mania: It helps quickly control and calm severe manic symptoms, such as racing thoughts, extreme restlessness, rapid speech, and impulsive behaviours.
  • Recurrent depression: It is sometimes used alongside other medications to treat persistent depression when standard antidepressants have not worked well enough on their own.

Key Benefits

Lithowel 450mg Tablet CR helps stabilise mood and reduce the symptoms of bipolar disorder. Key benefits include:

  • Stabilises mood: Helps reduce extreme mood swings and maintain a more balanced emotional state.
  • Helps manage manic episodes: Reduces symptoms such as racing thoughts, restlessness, rapid speech, and impulsive behaviour.
  • Supports long-term mental health: Helps lower the risk of future manic and depressive episodes when taken regularly as prescribed.
  • Supports emotional well-being: By improving mood stability, it can help you think more clearly, carry out daily activities, and maintain relationships more effectively.
Side effects of Lithowel 450mg Tablet CR
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
  • Reduce fluid intake 2-3 hours prior to bedtime.
  • Limit alcohol and caffeine as they can increase urination and affect bladder health.
  • Maintain sleep hygiene.
  • Eat a low-salt and healthy diet.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Directions for Use

  • Take Lithowel 450mg Tablet CR with food for better absorption, or take it as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Lithowel 450mg Tablet CR Works

Lithowel 450mg Tablet CR contains lithium carbonate, which works directly within the central nervous system to balance chemical messengers, known as neurotransmitters, in the brain. It helps reduce overactive brain signals that cause manic behavior while boosting the pathways that calm and stabilise your nervous system. By strengthening these pathways, the medicine protects brain cells from stress and helps regulate the genetic and biological factors that control your daily mood, keeping your emotions on a steady, manageable level.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Lithowel 450mg Tablet CR as it may increase the risk of side effects such as drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Lithowel 450mg Tablet CR is a Category D pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Lithowel 450mg Tablet CR as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Lithowel 450mg Tablet CR may cause dizziness, drowsiness or other severe adverse effects. Therefore, avoid driving if you feel drowsy or dizzy after taking Lithowel 450mg Tablet CR.

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Liver

Safe if prescribed

Lithowel 450mg Tablet CR is safe to use in patients with liver diseases/conditions if prescribed by a doctor.

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Kidney

Caution

Take Lithowel 450mg Tablet CR with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required. Lithowel 450mg Tablet CR is not recommended for patients with severe kidney problems.

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Children

Caution

Lithowel 450mg Tablet CR is generally not recommended for children below 12 years. However, Lithowel 450mg Tablet CR may be used in children above 7 years for treating bipolar disorder only if prescribed by a doctor.

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Heart

Unsafe

Lithowel 450mg Tablet CR should not be used in patients with severe heart disease. It should be taken only after seeking advice from your doctor, especially if you have or have had any heart problems.

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Geriatrics

Caution

Lithowel 450mg Tablet CR should be given with caution in elderly patients due to an increased risk of side effects. Please inform your doctor before use.

What if I have taken an overdose of Lithowel 450mg Tablet CR

If you take more than the prescribed amount of Lithowel 450mg Tablet CR, seek immediate medical attention. Symptoms of an overdose may include severe drowsiness, confusion, slurred speech, poor coordination, vomiting, diarrhoea, muscle weakness, tremors, or seizures

Diet & Lifestyle Advise

  • Keep fluid intake steady: Drink a consistent amount of water daily (usually 8 to 12 cups) to prevent dehydration, which can raise medicine levels to dangerous heights.
  • Maintain a stable salt intake: Do not suddenly start a low-salt diet or suddenly increase your salt intake, as changes in dietary sodium directly affect how your kidneys process Lithowel 450mg Tablet CR.
  • Limit caffeine: Avoid sudden changes in your consumption of coffee, tea, and soda, as caffeine can alter the clearance of this medicine from your system.
  • Avoid overheating: Be cautious during hot weather, heavy exercise, or during illnesses with fever or vomiting, as excessive sweating and dehydration can cause the medicine to build up dangerously.
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How Soon It Starts Working

The time required for Lithowel 450mg Tablet CR to start to work: The time required for Lithowel 450mg Tablet CR to show its action is unknown. The time for which the effects of Lithowel 450mg Tablet CR last: The duration of action for Lithowel 450mg Tablet CR is unknown.

What if you forget to take Lithowel 450mg Tablet CR

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is only a few hours away, skip the missed dose and return to your regular schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure.

Storage

•Store Lithowel 450mg Tablet CR at room temperature between 15°C and 30°C.• Keep the container tightly closed when not in use. Protect from moisture and direct light.

Drug Warnings

  • Keep all blood test appointments: Regular blood draws are absolutely necessary to ensure the drug remains in a safe therapeutic range.
  • Learn the early warning signs: Memorize the signs of toxicity (severe nausea, slurred speech, shakiness) so you can seek help immediately if they occur.
  • Check your pain relievers: Never start taking over-the-counter anti-inflammatory medicines like ibuprofen or naproxen without checking with your pharmacist first, as they can interact poorly.
  • Avoid alcohol: Alcohol can intensify side effects like drowsiness and increase your risk of dehydration.
  • Inform all healthcare providers: Tell all your doctors, dentists, and surgeons that you take Lithowel 450mg Tablet CR before any medical procedures or new prescriptions.

Drug-Drug Interactions

verifiedApollotooltip
  • NSAID pain relievers (like ibuprofen and naproxen): May increase the risk of toxicity by raising the level of Lithowel 450mg Tablet CR in your blood.
  • Diuretics (water pills) and ACE inhibitors (blood pressure drugs): Can cause a dangerous buildup of Lithowel 450mg Tablet CR in your body by reducing how much your kidneys can clear.
  • Certain antidepressants (like SSRIs): May increase the risk of a rare but serious condition called serotonin syndrome, causing confusion, rapid heart rate, and sweating.
LithiumCidofovir
Critical
LithiumCisapride
Critical

Drug-Drug Interactions

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LithiumCidofovir
Critical
How does the drug interact with Lithowel 450mg Tablet CR:
Cidofovir can cause higher levels of Lithowel 450mg Tablet CR carbonate in the blood which increases risk of kidney problems.

How to manage the interaction:
Taking Lithowel 450mg Tablet CR with Cidofovir is not recommended, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
LithiumCisapride
Critical
How does the drug interact with Lithowel 450mg Tablet CR:
Taking Cisapride with Lithowel 450mg Tablet CR can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Lithowel 450mg Tablet CR with Cisapride is not recommended as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LithiumCaptopril
Severe
How does the drug interact with Lithowel 450mg Tablet CR:
Taking Lithowel 450mg Tablet CR carbonate with Captopril may significantly increase the blood levels of Lithowel 450mg Tablet CR.

How to manage the interaction:
Taking Lithowel 450mg Tablet CR with Captopril together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst, and/or increased urination contact a doctor immediately. Do not stop using any medications without a doctor's advice.
LithiumHuman immunoglobulin
Severe
How does the drug interact with Lithowel 450mg Tablet CR:
Taking Human immunoglobulin with Lithowel 450mg Tablet CR may increase the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Lithowel 450mg Tablet CR together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
LithiumBupropion
Severe
How does the drug interact with Lithowel 450mg Tablet CR:
Taking Bupropion with Lithowel 450mg Tablet CR can increase the risk of seizures(fits).

How to manage the interaction:
Co-administration of bupropion along with Lithowel 450mg Tablet CR can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience any unusual symptoms like staring, stiffening of the legs and hands, stiffening of body, loss of consciousness, breathing difficulties or cessation, lack of urinary or bowel control, and Falling suddenly for no apparent reason, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LithiumFlurbiprofen
Severe
How does the drug interact with Lithowel 450mg Tablet CR:
Co-administration of Flurbiprofen with Lithowel 450mg Tablet CR may significantly increase the blood levels of Lithowel 450mg Tablet CR.

How to manage the interaction:
There may be a possibility of interaction between Flurbiprofen and Lithowel 450mg Tablet CR, but it can be taken if prescribed by a doctor. However, if you experience drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst and increased urination contact your doctor immediately. Do not stop using any medications without a doctor's advice.
LithiumHydrochlorothiazide
Severe
How does the drug interact with Lithowel 450mg Tablet CR:
Coadministration of Lithowel 450mg Tablet CR and Hydrochlorothiazide can increase the effects of Lithowel 450mg Tablet CR.

How to manage the interaction:
Taking Lithowel 450mg Tablet CR and Hydrochlorothiazide together can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
LithiumTrichlormethiazide
Severe
How does the drug interact with Lithowel 450mg Tablet CR:
Taking Lithowel 450mg Tablet CR and Trichlormethiazide together can increase the effects of Lithowel 450mg Tablet CR.

How to manage the interaction:
Although taking Trichlormethiazide and Lithowel 450mg Tablet CR together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness call your doctor. Do not stop using any medications without a doctor's advice.
LithiumOndansetron
Severe
How does the drug interact with Lithowel 450mg Tablet CR:
Taking ondansetron with Lithowel 450mg Tablet CR can increase the risk of serotonin syndrome a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking ondansetron along with Lithowel 450mg Tablet CR can result in an interaction but can be taken together if prescribed by a doctor. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools, or fast or rapid heartbeats during therapy, consult a doctor. Do not stop using any medications without talking to a doctor.
LithiumVilazodone
Severe
How does the drug interact with Lithowel 450mg Tablet CR:
Co-administration Vilazodone with Lithowel 450mg Tablet CR may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a interaction between Vilazodone and Lithowel 450mg Tablet CR, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Caffeine: Sudden changes in coffee, tea, or energy drink intake can lower the effectiveness of Lithowel 450mg Tablet CR or cause levels to rise if stopped abruptly.
  • Sodium (Salt): Major changes in daily salt intake can directly alter how your kidneys process and eliminate this medicine.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Lithowel 450mg Tablet CR belongs to a psychological class of drugs called 'anti-manic agents' or 'mood stabilizers' primarily used to prevent and treat mood disorders like mania and bipolar disorder.
Lithowel 450mg Tablet CR helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.
Lithowel 450mg Tablet CR is not recommended for hypothyroid (underactive thyroid gland) patients as it may increase the risk of low levels of thyroid hormone. Therefore, if you have hypothyroidism, please inform your doctor before taking Lithowel 450mg Tablet CR.
Lithowel 450mg Tablet CR may cause weight gain but it is not necessary for everyone taking Lithowel 450mg Tablet CR to experience this side effect. However, in order to avoid gaining weight while taking Lithowel 450mg Tablet CR, you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.
It is advised to inform your doctor if you are planning or had weight loss surgery as the dose may be adjusted accordingly based on lithium levels in blood.
Lithowel 450mg Tablet CR may cause dehydration especially if you have low sodium levels in the body or consume too much alcohol. However, if you notice dark, strong-smelling urine or a decrease in urination, it indicates that you are dehydrated, and this may affect lithium levels in the blood. Therefore, you are recommended to drink plenty of fluids while taking Lithowel 450mg Tablet CR to avoid dehydration.
You are not recommended to stop taking Lithowel 450mg Tablet CR without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Lithowel 450mg Tablet CR for as long as your doctor has prescribed it and if you experience any difficulty while taking Lithowel 450mg Tablet CR, please consult your doctor so that the dose may be gradually reduced.
You are not recommended to take Lithowel 450mg Tablet CR with fluoxetine or other antidepressants such as paroxetine and sertraline as co-administration of these medicines may increase the risk of a rare and serious condition known as serotonin syndrome. If you experience blurred vision, increased heart rate, hallucination, fits, confusion, muscle stiffness or spasm, vomiting, nausea, diarrhoea, excessive sweating, stomach cramps, fever, shaking, or shivering, please consult a doctor immediately. However, before using Lithowel 450mg Tablet CR with any other medicines, you are advised to contact your doctor.
It's important to inform your doctor about your hypertension and the medications you're taking for it as Lithowel 450mg Tablet CR can interact with certain blood pressure medications, and your doctor may need to adjust your treatment plan to ensure your safety.
No, you should not increase the dose of Lithowel 450mg Tablet CR on your own. It can take 1-3 weeks to feel the full effects, and increasing the dose without medical advice can be dangerous and may lead to adverse effects. However consult your doctor if you have any concerns.
Yes, Lithowel 450mg Tablet CR can cause sleepiness as a side effect. It's important to be cautious when performing activities that require alertness, such as driving or operating heavy machinery, until you know how the medication affects you.
Yes, Lithowel 450mg Tablet CR can affect the kidneys. Long-term use of lithium can lead to kidney problems, and regular monitoring of kidney function is necessary during treatment. It's important to inform your doctor if you have any pre-existing kidney conditions or if you experience any symptoms of kidney problems while taking Lithowel 450mg Tablet CR.
Lithowel 450mg Tablet CR should only be started if adequate facilities for assessing Lithowel 450mg Tablet CR levels are available. Because elevated levels of Lithowel 450mg Tablet CR are linked to Lithowel 450mg Tablet CR toxicity. Lithowel 450mg Tablet CR toxicity can even occur at dose which is effective for treatment. Therefore, your doctor may closely monitor your Lithowel 450mg Tablet CR levels weekly until stabilization is achieved, then weekly for one month and then at monthly intervals thereafter.
Lithowel 450mg Tablet CR should be taken as prescribed by your doctor. It is recommended to take with food to reduce nausea. Lithowel 450mg Tablet CR may be taken before or after meals. Swallow it as a whole with a glass of water. Do not crush, chew or break it.
Certain medications which decrease the levels of Lithowel 450mg Tablet CR in blood include carbonic anhydrase inhibitors, chlorpromazine, sodium-containing preparations, theophylline, urea and herbal medicines. Therefore, before starting Lithowel 450mg Tablet CR, inform your doctor about all the medicines you are taking.
The common side effects of Lithowel 450mg Tablet CR are loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. If any of these side effects persist or worsen, please consult your doctor.
Yes, regular blood tests are essential to ensure the medication level in your blood is effective but not toxic. Your doctor will also use these tests to monitor your kidney and thyroid function over time. Talk to your doctor to understand your testing schedule.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can worsen side effects like drowsiness and dizziness, and it can cause dehydration, which increases the risk of drug toxicity. Talk to your doctor or pharmacist if you have questions.
Early warning signs of high levels include severe vomiting, persistent diarrhea, severe hand tremors, lack of coordination, and slurred speech. If you notice any of these symptoms, seek emergency medical care immediately. Talk to your doctor for more details.
You should avoid common anti-inflammatory drugs like ibuprofen or naproxen, as they can raise the levels of Lithowel 450mg Tablet CR in your body to unsafe levels. Acetaminophen is generally a safer option, but you should always talk to your doctor or pharmacist before taking any new medicine.
Some individuals may experience mild weight gain while taking this medication due to water retention or changes in metabolism. Maintaining a balanced diet and regular exercise routine can help manage this. Talk to your doctor if weight changes become a concern.
Taking Lithowel 450mg Tablet CR during pregnancy can carry risks for the developing baby, particularly during the first trimester. If you are pregnant, planning to become pregnant, or breastfeeding, you must discuss the risks and benefits with your physician. Talk to your doctor to weigh your options.
No, you must not stop taking Lithowel 450mg Tablet CR suddenly, even if you feel completely healthy. Stopping the medicine abruptly can cause your mood symptoms to return or worsen. Talk to your doctor to discuss any changes to your treatment plan.

Disclaimer

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.10828 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 017812S033,018421S032,018558S027Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Lithium Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. National Health Service (NHS). Lithium - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 20 Feb. 2020]Check here
  6. Krutika Chokhawala, Sarah Lee, Abdolreza Saadabadi. Lithium. National Library of Medicine. National Center for Biotechnology Information. PubMed Central. May 2022. [Accessed on 13th February 2024]Check here

Country of origin

India
Other Info - LI34722
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