Lithium Carbonate
About Lithium Carbonate
Lithium Carbonate is a medication primarily prescribed to stabilise mood and treat manic episodes associated with bipolar disorder. It helps prevent and control severe mood swings, bringing emotional balance to those experiencing extreme highs and lows. This medicine plays a crucial role in long-term mental health management.
To get the best results, you must take Lithium Carbonate consistently at the same times every day as directed by your doctor. You can take this medication with or without food, though taking it with a meal can help prevent a mild upset stomach. Maintaining a highly consistent daily intake of fluids and dietary salt is also vital, as sudden changes can affect how your body handles the medicine.
While taking Lithium Carbonate, you may experience mild side effects like a slight hand tremor, increased thirst, or urinating more often. However, you must contact your doctor immediately if you experience severe hand shaking, persistent vomiting, severe diarrhoea, or slurred speech, as these can be signs of the medicine reaching unsafe levels in your blood.
Talk to your doctor before taking Lithium Carbonate if you have kidney disease, heart problems, thyroid issues, or if you are severely dehydrated. Do not take this if you have severe kidney failure, severe cardiovascular disease, untreated underactive thyroid, or severe dehydration, as the medicine can build up to dangerous levels in your body.
This medicine can interact with several other drugs, including common over-the-counter pain relievers, water pills, and certain blood pressure medicines, which can raise the amount of Lithium Carbonate in your blood and lead to side effects. You should also avoid alcohol, as it can worsen drowsiness and cause dehydration. If you are pregnant, breastfeeding, or an older adult, consult your doctor before starting Lithium Carbonate to discuss safe options.
Uses of Lithium Carbonate
Medicinal Benefits
Lithium Carbonate helps stabilise mood and reduce the symptoms of bipolar disorder. Key benefits include:
- Stabilises mood: Helps reduce extreme mood swings and maintain a more balanced emotional state.
- Helps manage manic episodes: Reduces symptoms such as racing thoughts, restlessness, rapid speech, and impulsive behaviour.
- Supports long-term mental health: Helps lower the risk of future manic and depressive episodes when taken regularly as prescribed.
- Supports emotional well-being: By improving mood stability, it can help you think more clearly, carry out daily activities, and maintain relationships more effectively.
Directions for Use
- Take Lithium Carbonate with food for better absorption, or take it as advised by the doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Swallow it as a whole with a glass of water.
- Do not crush, chew, or break it.
Storage
Side Effects of Lithium Carbonate
Common Side Effects (Usually mild)
- Mild hand trembling (tremors)
- Increased thirst and needing to urinate more frequently
- Mild nausea or a bloated feeling in the stomach
- Slight weight gain or mild fatigue
Serious Side Effects (Consult your doctor right away):
- Severe vomiting, persistent watery diarrhoea, or severe muscle weakness
- Slurred speech, clumsiness, difficulty walking, or extreme shakiness
- Confusion, severe drowsiness, or blurred vision
- Swelling in the neck, feeling unusually cold, or sudden fatigue (signs of thyroid issues)
- Signs of an allergic reaction, such as a severe skin rash, itching, or swelling of the face and throat
Medicines Containing this Salt
View AllDrug Warnings
- Keep all blood test appointments: Regular blood draws are absolutely necessary to ensure the drug remains in a safe therapeutic range.
- Learn the early warning signs: Memorize the signs of toxicity (severe nausea, slurred speech, shakiness) so you can seek help immediately if they occur.
- Check your pain relievers: Never start taking over-the-counter anti-inflammatory medicines like ibuprofen or naproxen without checking with your pharmacist first, as they can interact poorly.
- Avoid alcohol: Alcohol can intensify side effects like drowsiness and increase your risk of dehydration.
- Inform all healthcare providers: Tell all your doctors, dentists, and surgeons that you take Lithium Carbonate before any medical procedures or new prescriptions.
Drug Interactions
- NSAID pain relievers (like ibuprofen and naproxen): May increase the risk of toxicity by raising the level of Lithium Carbonate in your blood.
- Diuretics (water pills) and ACE inhibitors (blood pressure drugs): Can cause a dangerous buildup of Lithium Carbonate in your body by reducing how much your kidneys can clear.
- Certain antidepressants (like SSRIs): May increase the risk of a rare but serious condition called serotonin syndrome, causing confusion, rapid heart rate, and sweating.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended to avoid consumption of alcohol with Lithium Carbonate as it may increase the risk of side effects such as drowsiness, dizziness or difficulty in concentrating.
Pregnancy
unsafeLithium Carbonate is a Category D pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby.
Breast Feeding
unsafeAvoid breastfeeding while taking Lithium Carbonate as it may be excreted in breast milk and cause adverse effects in the baby.
Driving
unsafeLithium Carbonate may cause dizziness, drowsiness or other severe adverse effects. Therefore, avoid driving if you feel drowsy or dizzy after taking Lithium Carbonate.
Liver
safe if prescribedLithium Carbonate is safe to use in patients with liver diseases/conditions if prescribed by a doctor.
Kidney
cautionTake Lithium Carbonate with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required. Lithium Carbonate is not recommended for patients with severe kidney problems.
Children
cautionLithium Carbonate is generally not recommended for children below 12 years. However, Lithium Carbonate may be used in children above 7 years for treating bipolar disorder only if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Keep fluid intake steady: Drink a consistent amount of water daily (usually 8 to 12 cups) to prevent dehydration, which can raise medicine levels to dangerous heights.
- Maintain a stable salt intake: Do not suddenly start a low-salt diet or suddenly increase your salt intake, as changes in dietary sodium directly affect how your kidneys process Lithium Carbonate.
- Limit caffeine: Avoid sudden changes in your consumption of coffee, tea, and soda, as caffeine can alter the clearance of this medicine from your system.
- Avoid overheating: Be cautious during hot weather, heavy exercise, or during illnesses with fever or vomiting, as excessive sweating and dehydration can cause the medicine to build up dangerously.
Special Advise
Regular blood tests are advised every week while taking Lithium Carbonate to monitor the levels of lithium in blood. When lithium levels are constant, blood tests may be done every 3 months.
Drink a constant amount of water daily and maintain a constant sodium intake as any major changes in these two may alter the levels of lithium in blood.
Patients Concern
Disease/Condition Glossary
Mania: It is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or changes in sleep pattern, high levels of stress, and alcohol intake. Seek medical help immediately if you have any self-harming or suicidal thoughts.
Bipolar disorder: It is also called manic depression, a mental condition associated with extreme mood swings ranging from manic highs to depressive lows. The symptoms of bipolar disorder include mania (high energy and excitability) and depression (loss of interest, hopelessness, and low energy). Bipolar disorder involves lifelong treatment.
FAQs
Lithium Carbonate belongs to a psychological class of drugs called 'anti-manic agents' or 'mood stabilizers' primarily used to prevent and treat mood disorders like mania and bipolar disorder.
Lithium Carbonate helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.
Lithium Carbonate is not recommended for hypothyroid (underactive thyroid gland) patients as it may increase the risk of low levels of thyroid hormone. Therefore, if you have hypothyroidism, please inform your doctor before taking Lithium Carbonate.
Lithium Carbonate may cause weight gain but it is not necessary for everyone taking Lithium Carbonate to experience this side effect. However, in order to avoid gaining weight while taking Lithium Carbonate, you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.
It is advised to inform your doctor if you are planning or had weight loss surgery as the dose may be adjusted accordingly based on lithium levels in blood.
Lithium Carbonate may cause dehydration especially if you have low sodium levels in the body or consume too much alcohol. However, if you notice dark, strong-smelling urine or a decrease in urination, it indicates that you are dehydrated, and this may affect lithium levels in the blood. Therefore, you are recommended to drink plenty of fluids while taking Lithium Carbonate to avoid dehydration.
You are not recommended to stop taking Lithium Carbonate without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Lithium Carbonate for as long as your doctor has prescribed it and if you experience any difficulty while taking Lithium Carbonate, please consult your doctor so that the dose may be gradually reduced.
You are not recommended to take Lithium Carbonate with fluoxetine or other antidepressants such as paroxetine and sertraline as co-administration of these medicines may increase the risk of a rare and serious condition known as serotonin syndrome. If you experience blurred vision, increased heart rate, hallucination, fits, confusion, muscle stiffness or spasm, vomiting, nausea, diarrhoea, excessive sweating, stomach cramps, fever, shaking, or shivering, please consult a doctor immediately. However, before using Lithium Carbonate with any other medicines, you are advised to contact your doctor.
It's important to inform your doctor about your hypertension and the medications you're taking for it as Lithium Carbonate can interact with certain blood pressure medications, and your doctor may need to adjust your treatment plan to ensure your safety.
No, you should not increase the dose of Lithium Carbonate on your own. It can take 1-3 weeks to feel the full effects, and increasing the dose without medical advice can be dangerous and may lead to adverse effects. However consult your doctor if you have any concerns.
Yes, Lithium Carbonate can cause sleepiness as a side effect. It's important to be cautious when performing activities that require alertness, such as driving or operating heavy machinery, until you know how the medication affects you.
Yes, Lithium Carbonate can affect the kidneys. Long-term use of lithium can lead to kidney problems, and regular monitoring of kidney function is necessary during treatment. It's important to inform your doctor if you have any pre-existing kidney conditions or if you experience any symptoms of kidney problems while taking Lithium Carbonate.
Lithium Carbonate should only be started if adequate facilities for assessing Lithium Carbonate levels are available. Because elevated levels of Lithium Carbonate are linked to Lithium Carbonate toxicity. Lithium Carbonate toxicity can even occur at dose which is effective for treatment. Therefore, your doctor may closely monitor your Lithium Carbonate levels weekly until stabilization is achieved, then weekly for one month and then at monthly intervals thereafter.
Lithium Carbonate should be taken as prescribed by your doctor. It is recommended to take with food to reduce nausea. Lithium Carbonate may be taken before or after meals. Swallow it as a whole with a glass of water. Do not crush, chew or break it.
Certain medications which decrease the levels of Lithium Carbonate in blood include carbonic anhydrase inhibitors, chlorpromazine, sodium-containing preparations, theophylline, urea and herbal medicines. Therefore, before starting Lithium Carbonate, inform your doctor about all the medicines you are taking.
The common side effects of Lithium Carbonate are loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. If any of these side effects persist or worsen, please consult your doctor.
Yes, regular blood tests are essential to ensure the medication level in your blood is effective but not toxic. Your doctor will also use these tests to monitor your kidney and thyroid function over time. Talk to your doctor to understand your testing schedule.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can worsen side effects like drowsiness and dizziness, and it can cause dehydration, which increases the risk of drug toxicity. Talk to your doctor or pharmacist if you have questions.
Early warning signs of high levels include severe vomiting, persistent diarrhea, severe hand tremors, lack of coordination, and slurred speech. If you notice any of these symptoms, seek emergency medical care immediately. Talk to your doctor for more details.
You should avoid common anti-inflammatory drugs like ibuprofen or naproxen, as they can raise the levels of Lithium Carbonate in your body to unsafe levels. Acetaminophen is generally a safer option, but you should always talk to your doctor or pharmacist before taking any new medicine.
Some individuals may experience mild weight gain while taking this medication due to water retention or changes in metabolism. Maintaining a balanced diet and regular exercise routine can help manage this. Talk to your doctor if weight changes become a concern.
Taking Lithium Carbonate during pregnancy can carry risks for the developing baby, particularly during the first trimester. If you are pregnant, planning to become pregnant, or breastfeeding, you must discuss the risks and benefits with your physician. Talk to your doctor to weigh your options.
No, you must not stop taking Lithium Carbonate suddenly, even if you feel completely healthy. Stopping the medicine abruptly can cause your mood symptoms to return or worsen. Talk to your doctor to discuss any changes to your treatment plan.

