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  1. Home
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  3. Synlit-450 Tablet 10's

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Synlit-450 Tablet 10's, Pack of 10 TabletS
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Synlit-450 Tablet 10's belongs to the class of antipsychotic medicine used in the treatment of bipolar disorder and mania. This medicine suppresses the excess and abnormal activity of nerve cells in the brain by increasing the activity of chemical messengers in the brain. Common side effects include loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination.
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Composition :

LITHIUM CARBONATE-450MG

Manufacturer/Marketer :

Salutifer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Synlit-450 Tablet 10's

Synlit-450 Tablet 10's belongs to a psychological class of drugs called 'anti-manic agents' or 'mood stabilizers' primarily used to prevent and treat mood disorders like mania and bipolar disorder. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Bipolar disorder is a mental condition associated with extreme mood swings ranging from the hyper stage of mania to low mood depression.

Synlit-450 Tablet 10's contains Lithium carbonate that helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Take Synlit-450 Tablet 10's as prescribed. Your doctor will advise you on how often you need to take Synlit-450 Tablet 10's based on your medical condition. Some people may experience loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. Most of these side effects of Synlit-450 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Synlit-450 Tablet 10's or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Synlit-450 Tablet 10's. Regular blood tests are recommended while taking Synlit-450 Tablet 10's to monitor the levels of lithium in blood. If you have fits, kidney or heart problems, thyroid, persistent headache, vision problems, and if you are planning or had weight loss surgery, please inform your doctor before taking Synlit-450 Tablet 10's.

Uses of Synlit-450 Tablet 10's

Synlit-450 Tablet 10's is used to manage and prevent mood disorders by stabilizing emotional fluctuations. The detailed uses of Synlit-450 Tablet 10's are as follows:

  • Treatment of mania: Synlit-450 Tablet 10's is used to control abnormal hyperactivity and unstable mood associated with manic episodes.
  • Management of bipolar depression: Synlit-450 Tablet 10's stabilizes mood swings in individuals with bipolar disorder, reducing episodes of depression and mania.
  • Prevention of recurrent affective disorders: Synlit-450 Tablet 10's is indicated to reduce the frequency and severity of recurrent depression.

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Directions for Use

  • Take Synlit-450 Tablet 10's with food for better absorption, or take it as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Synlit-450 Tablet 10's is a mood stabilizer that is used to prevent and treat mood disorders such as mania and bipolar disorder. Synlit-450 Tablet 10's contains Lithium carbonate that helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood. Thus, Synlit-450 Tablet 10's relaxes nerves and calms the mood, which helps in having a better social life and enables to do daily activities comfortably.

How Synlit-450 Tablet 10's Works

Synlit-450 Tablet 10's contains Lithium carbonate that helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Storage

• Store in a cool and dry place away from sunlight.• Keep Synlit-450 Tablet 10's out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Synlit-450 Tablet
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
  • Reduce fluid intake 2-3 hours prior to bedtime.
  • Limit alcohol and caffeine as they can increase urination and affect bladder health.
  • Maintain sleep hygiene.
  • Eat a low-salt and healthy diet.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

What if I have taken an overdose of Synlit-450 Tablet 10's

Take Synlit-450 Tablet 10's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include vomiting, diarrhoea, muscular weakness, drowsiness, and lack of coordination. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Regular blood tests are recommended while taking Synlit-450 Tablet 10's to check lithium levels in the blood. If you are pregnant or breastfeeding, please inform your doctor before taking Synlit-450 Tablet 10's. If you have hypothyroidism (underactive thyroid gland), please inform your doctor before taking Synlit-450 Tablet 10's as it may cause low thyroid levels. If you notice decreased amount of urine, dark, reddish urine, muscle pain or weakness, inform your doctor immediately as it may be due to a serious condition called rhabdomyolysis (muscle tissue breakdown) which may lead to kidney problems.

Drug-Drug Interactions

verifiedApollotooltip
LithiumCidofovir
Critical
LithiumCisapride
Critical

Drug-Drug Interactions

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LithiumCidofovir
Critical
How does the drug interact with Synlit-450 Tablet:
Cidofovir can cause higher levels of Synlit-450 Tablet carbonate in the blood which increases risk of kidney problems.

How to manage the interaction:
Taking Synlit-450 Tablet with Cidofovir is not recommended, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
LithiumCisapride
Critical
How does the drug interact with Synlit-450 Tablet:
Taking Cisapride with Synlit-450 Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Synlit-450 Tablet with Cisapride is not recommended as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LithiumPhenelzine
Severe
How does the drug interact with Synlit-450 Tablet:
Taking Synlit-450 Tablet with Phenelzine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a interaction between Phenelzine and Synlit-450 Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
LithiumPerindopril
Severe
How does the drug interact with Synlit-450 Tablet:
Perindopril when taken together with Synlit-450 Tablet may significantly increase the blood levels of Synlit-450 Tablet.

How to manage the interaction:
Although there is drug interaction between perindopril and Synlit-450 Tablet, but can be taken together if advised by a doctor. if experience dizziness, confusion, diarrhea, vomiting, muscle weakness, tremor (shaking of hand & legs) blurred vision, ringing in the ear, excessive thirst, and/or increased urination consult a doctor immediately. Do not discontinue medications without consulting a doctor.
LithiumEverolimus
Severe
How does the drug interact with Synlit-450 Tablet:
Taking Synlit-450 Tablet with Everolimus may increase the risk of kidney problems.

How to manage the interaction:
Although taking Everolimus and Synlit-450 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
LithiumHydroxychloroquine
Severe
How does the drug interact with Synlit-450 Tablet:
Taking Synlit-450 Tablet with Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Synlit-450 Tablet and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
LithiumPhenylbutazone
Severe
How does the drug interact with Synlit-450 Tablet:
Taking Synlit-450 Tablet and Phenylbutazone together may significantly increase the blood levels of Synlit-450 Tablet.

How to manage the interaction:
Co-administration of Synlit-450 Tablet with Phenylbutazone can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor if you experience drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst, or increased urination. Do not stop using any medications without a doctor's advice.
LithiumSertraline
Severe
How does the drug interact with Synlit-450 Tablet:
Taking Synlit-450 Tablet with Sertraline can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Sertraline and Synlit-450 Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
LithiumCeritinib
Severe
How does the drug interact with Synlit-450 Tablet:
Taking Synlit-450 Tablet together with Ceritinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Ceritinib with Synlit-450 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
LithiumOndansetron
Severe
How does the drug interact with Synlit-450 Tablet:
Taking ondansetron with Synlit-450 Tablet can increase the risk of serotonin syndrome a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking ondansetron along with Synlit-450 Tablet can result in an interaction but can be taken together if prescribed by a doctor. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools, or fast or rapid heartbeats during therapy, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a constant sodium diet as it may affect lithium levels in the blood and cause adverse effects.
  • Limit the intake of caffeine as it may reduce the effectiveness of Synlit-450 Tablet 10's.
  • Do regular exercise and maintain a stable weight as Synlit-450 Tablet 10's may cause weight gain.
  • Drink plenty of water to avoid dehydration and try to drink the same amount of water every day as any major changes in quantity may affect lithium levels.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Synlit-450 Tablet 10's as it may increase the risk of side effects such as drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Synlit-450 Tablet 10's is a Category D pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Synlit-450 Tablet 10's as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Synlit-450 Tablet 10's may cause dizziness, drowsiness or other severe adverse effects. Therefore, avoid driving if you feel drowsy or dizzy after taking Synlit-450 Tablet 10's.

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Liver

Safe if prescribed

Synlit-450 Tablet 10's is safe to use in patients with liver diseases/conditions if prescribed by a doctor.

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Kidney

Caution

Take Synlit-450 Tablet 10's with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required. Synlit-450 Tablet 10's is not recommended for patients with severe kidney problems.

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Children

Caution

Synlit-450 Tablet 10's is generally not recommended for children below 12 years. However, Synlit-450 Tablet 10's may be used in children above 7 years for treating bipolar disorder only if prescribed by a doctor.

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Heart

Synlit-450 Tablet 10's should not be used in patients with severe heart disease. It should be taken only after seeking advice from your doctor, especially if you have or have had any heart problems.

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Geriatrics

Caution

Synlit-450 Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. Please inform your doctor before use.

FAQs

Synlit-450 Tablet 10's belongs to a psychological class of drugs called 'anti-manic agents' or 'mood stabilizers' primarily used to prevent and treat mood disorders like mania and bipolar disorder.

Synlit-450 Tablet 10's helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Synlit-450 Tablet 10's is not recommended for hypothyroid (underactive thyroid gland) patients as it may increase the risk of low levels of thyroid hormone. Therefore, if you have hypothyroidism, please inform your doctor before taking Synlit-450 Tablet 10's.

Synlit-450 Tablet 10's may cause weight gain but it is not necessary for everyone taking Synlit-450 Tablet 10's to experience this side effect. However, in order to avoid gaining weight while taking Synlit-450 Tablet 10's, you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.

It is advised to inform your doctor if you are planning or had weight loss surgery as the dose may be adjusted accordingly based on lithium levels in blood.

Country of origin

India

Manufacturer/Marketer address

335,Garg Plaza,Bhera enclave,Paschim vihar,New Delhi-110087
Other Info - SYN0115

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Oct 14, 2025 | 1:12 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.10828.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/017812s033,018421s032,018558s027lbl.pdf
  3. https://www.drugs.com/lithium.html
  4. https://www.nhs.uk/medicines/lithium/

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