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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
LO 50 Tablet is used to treat high blood pressure (hypertension), chronic heart failure, and diabetic nephropathy. It is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart). It contains Losartan, which works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. In some cases, you may experience dizziness, tiredness, low blood pressure, weakness, anaemia (lack of blood), hyperkalaemia (high potassium levels in the blood), change in kidney function, orthostatic hypotension (low blood pressure when standing up from lying or sitting position) or hypoglycaemia (low blood sugar).
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Whats That

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Composition :

LOSARTAN-50MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About LO 50 Tablet

LO 50 Tablet is used to treat high blood pressure (hypertension), chronic heart failure, and diabetic nephropathy. It is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart).

LO 50 Tablet contains Losartan, which works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

In some cases, you may experience dizziness, tiredness, low blood pressure, weakness, anaemia (lack of blood), hyperkalaemia (high potassium levels in the blood), change in kidney function, orthostatic hypotension (low blood pressure when standing up from lying or sitting position) or hypoglycaemia (low blood sugar). Most of these side effects of LO 50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are known to be allergic to LO 50 Tablet or any other medicines, please tell your doctor. It is advised to complete a full course of medication and not stop taking LO 50 Tablet suddenly, as it may cause recurring symptoms or worsen the condition. LO 50 Tablet is not recommended for pregnant, breastfeeding women and children below six years of age. Do not consume alcohol with LO 50 Tablet as it may increase the risk of low blood pressure. 

Uses of LO 50 Tablet

Treatment of High blood pressure (hypertension), diabetic nephropathy, and prevention of heart failure/stroke.

Directions for Use

LO 50 Tablet should be swallowed as a whole with water; do not crush or chew it.

Medicinal Benefits

LO 50 Tablet belongs to a class of drugs known as angiotensin II receptor blockers used to treat high blood pressure (hypertension), chronic heart failure, and diabetic nephropathy. It is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart). LO 50 Tablet contains Losartan, which works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

How LO 50 Tablet Works

LO 50 Tablet contains Losartan, which works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

Storage

Store in a cool and dry place away from sunlight
Side effects of LO 50 Tablet
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Muscle cramps can be treated with regular exercise or yoga, which includes mild stretching, which helps strengthen the lower body.
  • Warm baths and gentle massage of the affected parts can help relieve cramps.
  • Avoid strenuous activity and take frequent breaks, as rest is critical.
  • Intake of nutritious food can help strengthen body and mind. A trained nutritionist can help design a balanced diet for strengthening muscles.
  • Speak to your doctor if the pain lasts an extended period. Medical help can be practical in finding a cure for cramps.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.

What if I have taken an overdose of LO 50 Tablet

Do not take more than the prescribed dose of LO 50 Tablet as it may cause overdose. The symptoms of overdose include dizziness, fainting, fast or slow heartbeat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you have diabetes, kidney or liver problems, please inform your doctor before taking LO 50 Tablet. LO 50 Tablet is not recommended for pregnant women, especially in the second and third trimesters, as it may cause serious harm to the unborn baby (fetus). Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking LO 50 Tablet. Do not consume alcohol with LO 50 Tablet as it may increase the risk of low blood pressure. Avoid potassium supplements with LO 50 Tablet as they may lead to high potassium levels in the blood. Regular blood tests and blood pressure monitoring are recommended while taking LO 50 Tablet.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with LO 50 Tablet:
Coadministration of ramipril together with LO 50 Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Taking LO 50 Tablet with Ramipril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with LO 50 Tablet:
Coadministration of amiloride with LO 50 Tablet may increase potassium levels in the blood. 9High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Taking amiloride along with LO 50 Tablet may lead to an interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanCaptopril
Severe
How does the drug interact with LO 50 Tablet:
Coadministration of LO 50 Tablet with Captopril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking LO 50 Tablet with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with LO 50 Tablet:
Coadministration of LO 50 Tablet with Spironolactone can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking LO 50 Tablet with Spironolactone is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
LosartanPotassium citrate
Severe
How does the drug interact with LO 50 Tablet:
Coadministration of LO 50 Tablet with Potassium citrate can increase potassium levels, which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking LO 50 Tablet with Potassium citrate together can result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
How does the drug interact with LO 50 Tablet:
Co-administration of LO 50 Tablet with Potassium chloride may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood), which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Taking LO 50 Tablet with Potassium chloride together can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is advised to reduce the intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes. Do not discontinue any medications without a doctor's advice.
How does the drug interact with LO 50 Tablet:
Using enalapril together with LO 50 Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Enalapril with LO 50 Tablet may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
How does the drug interact with LO 50 Tablet:
Coadministration of LO 50 Tablet with Lisinopril can increase potassium levels.

How to manage the interaction:
Taking LO 50 Tablet with Lisinopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with LO 50 Tablet:
Coadministration of LO 50 Tablet with Quinapril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking LO 50 Tablet with Quinapril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with LO 50 Tablet:
Coadministration of LO 50 Tablet with Benazepril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.

How to manage the interaction:
Taking LO 50 Tablet with Benazepril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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LOSARTAN-50MGPotassium rich foods
Moderate

Drug-Food Interactions

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LOSARTAN-50MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking LO 50 Tablet with potassium-rich foods can increase the risk or severity of side effects like weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Do not stop using any medications without first talking to your doctor. Avoid taking potassium-rich foods (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) along with LO 50 Tablet. If you experience any nausea, vomiting, weakness, confusion, tingling of the hands and feet, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Diet & Lifestyle Advise

  • Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in fruits, vegetables, whole grains and low-fat dairy products.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with LO 50 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Unsafe

When LO 50 Tablet is used in the pregnancy during the 2nd and 3rd trimesters it affects the renin-angiotensin system can cause injury and even death to the unborn baby. So when pregnancy is detected, LO 50 Tablet should be discontinued as soon as possible.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking LO 50 Tablet as it may be unsafe for the baby.

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Driving

Caution

LO 50 Tablet may cause dizziness or drowsiness in some people. So, drive only if you are alert after taking LO 50 Tablet.

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Liver

Caution

LO 50 Tablet should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

LO 50 Tablet should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

It is not recommended for children below 6 years. However, for children above 6 years, give LO 50 Tablet in doses as prescribed by a doctor.

Have a query?

FAQs

LO 50 Tablet is used to treat high blood pressure (hypertension), chronic heart failure, and diabetic nephropathy. It is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart).

LO 50 Tablet works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

No, LO 50 Tablet is not recommended for use during pregnancy especially in the second and third trimesters as it may harm the developing baby. Therefore, if you are pregnant or planning for pregnancy, please inform your doctor before taking LO 50 Tablet.

You are not recommended to take more than the prescribed dose of LO 50 Tablet as it may cause LO 50 Tablet overdose resulting in symptoms such as low blood pressure, fast or slow heartbeat. However, if you experience any of these symptoms while taking LO 50 Tablet, please consult a doctor immediately.

No, you are not recommended to take ibuprofen with LO 50 Tablet as co-administration of these two medicines may reduce the effect of LO 50 Tablet and increase the risk of impaired kidney function. However, if you experience loss of appetite, sudden weight loss or weight gain, weakness, muscle cramps, vomiting, nausea, decreased or increased urination, irregular heart rhythm and fluid retention, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted to use safely.

No, you are not recommended to take potassium supplements with LO 50 Tablet as it may increase the levels of potassium in blood (hyperkalaemia). However, please consult a doctor before taking other medicines with LO 50 Tablet.

LO 50 Tablet may be safe for diabetic patients if it is prescribed by a doctor. LO 50 Tablet protects kidney and slows down the decrease of kidney function in hypertensive (high blood pressure) type 2 diabetic patients.

If you have any kidney problems, it is advised to inform your doctor before taking LO 50 Tablet. LO 50 Tablet may worsen kidneys function if there is any existing kidney problem. However, if you experience unexplained weight gain, swelling in feet, ankles or hands, please consult your doctor immediately.

Inform your doctor about all of your past and present diseases, particularly diabetes and all the ongoing medications, supplements and herbal medicines that you are taking. If you take insulin or antidiabetic medication, monitor your blood sugar carefully while taking LO 50 Tablet, especially in the first month of use. Using these diabetes medicines while taking LO 50 Tablet may cause significant changes in your blood sugar levels due to drug-drug interactions.

Yes, avoid foods high in potassium such as banana, spinach, kidney beans and peas. Also, avoid health supplements rich in potassium content. Maintain a low-salt diet.

Yes, LO 50 Tablet can make you feel dizzy. This may occur when you suddenly get up from a sitting or lying position. Therefore, rise slowly if you have been sitting or lying down to lower the chance of feeling dizzy or passing out.

Many people use LO 50 Tablet to lower blood pressure. In general, it has very few side effects. Also, it protects kidney function in high blood pressure patients having diabetes and impaired kidney function (diabetic nephropathy). It is also used to treat chronic heart failure when treatment with other medicines are not effective. Additionally, it helps to lower the risk of stroke in hypertensive patients and have thicker left ventricle (heart chamber).

Lifestyle changes play a key role to maintain your healthy if you are taking LO 50 Tablet. Maintain low-salt diet and find ways to reduce or manage stress in your life. Practice meditation or yoga or take up a hobby. Make sure that you have a sound sleep each night as this also helps to reduce stress levels and helps to maintain normal blood pressure. Avoid smoking and alcohol consumption. Take a diet that is rich in fruits, vegetables, whole grains and low-fat dairy products.

You may have to take LO 50 Tablet for a long term, may be for the rest of your life as LO 50 Tablet only controls blood pressure but does not cure it. Do not stop taking LO 50 Tablet without consulting your doctor. If you have any concerns, please consult your doctor.

No, LO 50 Tablet does not cause weight gain. However, if it starts affecting your kidney function then your body may swell due to the build-up of water, resulting in weight gain. If you experience unexplained weight gain or swelling in your ankles, feet or hands, consult your doctor.

Long-term use of LO 50 Tablet is generally considered to be safe. However, in some cases, prolonged use may adversely affect the kidneys functioning. Therefore, your doctor may recommend regular blood tests to monitor the kidneys functioning.

Yes, LO 50 Tablet may impair kidney function in patients, particularly those with chronic kidney disease, severe heart failure, or narrow or blocked blood vessels that lead to the kidneys (renal artery stenosis). Also, it may affect patients who have experienced dehydration or severe fluid loss due to diarrhea, vomiting, or excessive use of diuretics. Therefore, LO 50 Tablet should be used with caution in such patients and their kidney function should be monitored regularly.

It takes around 6 hours for LO 50 Tablet to start lowering blood pressure and the effect lasts for about 24 hours. However, you might need to take it for about 3-6 weeks to see the full benefits.

Take LO 50 Tablet exactly as advised by your doctor. You can take it with or without food. Swallow it as whole with a glass of water. Do not crush, chew or break it. Take it at the same time every day for effective results.

Taking LO 50 Tablet during the second and third trimesters of pregnancy can cause serious harm or even death of the developing fetus. Therefore, it is important to inform the doctor if you are pregnant or planning pregnancy. If you become pregnant while taking LO 50 Tablet, stop taking it and consult your doctor immediately.

The common side effects of LO 50 Tablet are dizziness, colds (upper respiratory infection), stuffy nose and back pain. If these side effects persist or worsen, please consult your doctor.

Yes, always inform your doctor about all the prescription and non-prescription medicines, herbal supplements and vitamins you are taking to avoid drug interactions.

Store LO 50 Tablet at room temperature in a cool and dry place. Protect from light. Keep it out of reach and sight of children.

Country of origin

India
Other Info - LO53555

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