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  3. Lokit-20 Capsule 10's

Lokit-20 Capsule 10's, Pack of 10 CAPSULES
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Lokit-20 Capsule is used to treat gastroesophageal reflux disease (GERD), peptic ulcer (stomach or duodenal ulcer), and Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour). It contains Omeprazole, which helps reduce stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), acid reflux, or heartburn. It may cause common side effects such as stomach pain, gas formation (flatulence), nausea, vomiting, diarrhoea, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Composition :

OMEPRAZOLE-20MG

Manufacturer/Marketer :

Sarabhai Chemicals (India) Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lokit-20 Capsule

Lokit-20 Capsule belongs to the class of drugs known as proton pump inhibitors (PPIs) used to treat gastroesophageal reflux disease (GERD), peptic ulcer (stomach or duodenal ulcer), and Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour). Normally, a thick layer of mucous protects the stomach against its own acid secretion. But, in the long run, it gets eroded by excessive stomach acid production, leading to complications like GERD, peptic ulcer, and Zollinger-Ellison syndrome.

Lokit-20 Capsule contains omeprazole (a proton pump inhibitor), which helps reduce stomach acid by blocking the actions of an enzyme called H+/K+ ATPase (gastric proton pump). This proton pump lies in the stomach wall cells and is responsible for releasing gastric acid. Lokit-20 Capsule prevents the release of stomach acid and relieves symptoms such as food pipe lining inflammation (esophagitis), acid reflux, or heartburn.

Your doctor will decide the dose and duration of Lokit-20 Capsule based on your medical condition. Lokit-20 Capsule may cause common side effects like stomach pain, gas formation (flatulence), nausea, vomiting, diarrhoea, and headache. These side effects are temporary and may resolve on their own. However, if the side effects persist or worsen, consult your doctor.

Before taking Lokit-20 Capsule , inform your doctor if you are allergic to any of its components or to other proton pump inhibitors. Also, tell your doctor if you have stomach or intestinal cancer, severe liver problems, difficulty swallowing, bloody or black stools, unexplained weight loss, or will have an endoscopy in the future. Lokit-20 Capsule should not be given to patients suffering from Clostridium difficile-associated diarrhoea. Avoid prolonged use of Lokit-20 Capsule , as it may increase the risk of osteoporosis-related fractures of the hip, wrist, or spine due to loss of magnesium. Consult your doctor before taking Lokit-20 Capsule if you are pregnant or breastfeeding.

Uses of Lokit-20 Capsule

Lokit-20 Capsule is used to reduce the amount of acid your stomach produces. It is commonly prescribed to treat:

  • Gastroesophageal Reflux Disease (GERD) – a condition where stomach acid flows back into the esophagus, causing heartburn and discomfort.
  • Peptic Ulcers – sores in the lining of the stomach or the upper part of the small intestine (duodenum), often caused by Helicobacter pylori infection or non-steroidal anti-inflammatory drugs (NSAIDs).
  • Zollinger-Ellison Syndrome – a rare condition in which tumors in the pancreas or duodenum cause the stomach to produce too much acid.
  • Erosive Esophagitis – helps heal damage to the esophagus caused by stomach acid and prevents it from returning.
  • Symptom Relief – reduces common symptoms like heartburn, bloating, and stomach pain by lowering acid levels.
  • Bleeding Prevention – reduces the risk of upper digestive tract bleeding in critically ill patients by protecting the stomach and esophagus lining.

Directions for Use

  • Lokit-20 Capsule can be taken with or without food. However, it is recommended to take it 30-60 minutes before a meal, preferably in the morning, for optimal effectiveness.
  • It is typically administered once daily, but your doctor will determine the exact dose and timing based on your specific medical condition.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Medicinal Benefits

Lokit-20 Capsule is effective in relieving symptoms of gastroesophageal reflux disease (heartburn), Zollinger-Ellison syndrome, and peptic ulcers (stomach or duodenal ulcers), as well as healing erosive esophagitis (inflammation of the food pipe). Lokit-20 Capsule contains omeprazole, which works by irreversibly blocking the proton pump gate (which secretes stomach acid).

How Lokit-20 Capsule Works

Lokit-20 Capsule contains omeprazole (a proton pump inhibitor), which helps reduce stomach acid by blocking the actions of an enzyme called H+/K+ ATPase (gastric proton pump). This proton pump lies in the stomach wall cells and is responsible for releasing gastric acid. Lokit-20 Capsule prevents the release of stomach acid and relieves symptoms such as food pipe lining inflammation (esophagitis), acid reflux, or heartburn.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Lokit-20 Capsule
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of Lokit-20 Capsule

Do not take more than the prescribed dose of Lokit-20 Capsule , as it may cause an overdose. The symptoms of an overdose include blurred vision, confusion, drowsiness, vomiting, nausea, sweating, fast or pounding heartbeat, flushing (feeling of warmth), headache, and dry mouth. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Lokit-20 Capsule if you are allergic to any of its components, other proton pump inhibitors, or if you are taking medications for HIV such as nelfinavir. Inform your doctor if you have stomach or intestinal cancer, severe liver problems, difficulty swallowing, bloody or black stools, unexplained weight loss, hypomagnesemia (low blood magnesium levels), stomach problems (such as pain or indigestion), or will have an endoscopy in the future. Lokit-20 Capsule should not be given to patients suffering from Clostridium difficile-associated diarrhoea. Avoid prolonged use of Lokit-20 Capsule , as it may increase the risk of osteoporosis-related fractures of the hip, wrist, or spine due to loss of magnesium. Consult your doctor before taking Lokit-20 Capsule if you are pregnant or breastfeeding. Lokit-20 Capsule should not be given to children under 1 year of age.

Drug-Drug Interactions

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OmeprazoleRilpivirine
Critical
OmeprazoleErlotinib
Critical

Drug-Drug Interactions

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OmeprazoleRilpivirine
Critical
How does the drug interact with Lokit-20 Capsule:
Using rilpivirine together with Lokit-20 Capsule can decrease the absorption and blood levels of rilpivirine.

How to manage the interaction:
Taking Lokit-20 Capsule with Rilpivirine can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
OmeprazoleErlotinib
Critical
How does the drug interact with Lokit-20 Capsule:
Lokit-20 Capsule can make Erlotinib less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Lokit-20 Capsule and Erlotinib together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
OmeprazoleItraconazole
Severe
How does the drug interact with Lokit-20 Capsule:
Co-administration of Lokit-20 Capsule with itraconazole can lessen the amount or effects of itraconazole.

How to manage the interaction:
Although taking Itraconazole along with Lokit-20 Capsule can cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
OmeprazoleGefitinib
Severe
How does the drug interact with Lokit-20 Capsule:
When taken together Lokit-20 Capsule may interfere with the absorption of gefitinib into the bloodstream and reduce its effectiveness.

How to manage the interaction:
Although taking Lokit-20 Capsule with gefitinib can lead to interaction, they can be taken if recommended by a doctor. However, if you have no other treatment options, it is suggested that you take gefitinib 12 hours before or after Lokit-20 Capsule to reduce the impact of the interaction. Do not stop using any medications without talking to a doctor.
OmeprazoleTacrolimus
Severe
How does the drug interact with Lokit-20 Capsule:
Taking tacrolimus with Lokit-20 Capsule may significantly increase the blood levels of tacrolimus, which may increase the risk of serious side effects (high sugars, infections, kidney problems, hyperkalemia - high blood levels of potassium).

How to manage the interaction:
Although taking Lokit-20 Capsule with tacrolimus can lead to interaction, they can be taken if recommended by a doctor. However, consult the doctor if you experience irregular heart rhythm, palpitations (fast heartbeat), muscle spasm, tremor (shaking of hands & legs), and seizures(fits). Do not stop using any medications without talking to a doctor.
OmeprazoleNelfinavir
Severe
How does the drug interact with Lokit-20 Capsule:
Using Lokit-20 Capsule in conjunction with nelfinavir can reduce the effectiveness of nelfinavir.

How to manage the interaction:
Although taking Lokit-20 Capsule with nelfinavir can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleCitalopram
Severe
How does the drug interact with Lokit-20 Capsule:
When Lokit-20 Capsule is used with citalopram the blood levels of citalopram may increase, increasing the risk of certain adverse effects, such as an abnormal heart rhythm, which can be serious.

How to manage the interaction:
Although taking Lokit-20 Capsule and citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid/pounding heartbeats while taking these medications, consult the doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleAcalabrutinib
Severe
How does the drug interact with Lokit-20 Capsule:
Lokit-20 Capsule, through decreasing stomach acidity, may interfere with the absorption of acalabrutinib capsules and reduce their effectiveness.

How to manage the interaction:
Although taking Lokit-20 Capsule with acalabrutinib can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleMethotrexate
Severe
How does the drug interact with Lokit-20 Capsule:
Coadministration of Lokit-20 Capsule with methotrexate may increase the levels and side effects of Lokit-20 Capsule.

How to manage the interaction:
Although there is a possible interaction between Lokit-20 Capsule and methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
OmeprazoleDasatinib
Severe
How does the drug interact with Lokit-20 Capsule:
Taking Lokit-20 Capsule and Dasatinib together may decrease the blood levels of Dasatinib.

How to manage the interaction:
Although taking Lokit-20 Capsule with Dasatinib can lead to interaction, they can be taken if recommended by a doctor. If you experience any unusual symptoms, visit a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
  • Include high-fibre containing foods, berries, cherries, leafy green veggies (kale, spinach), and black peppers in your meal. These foods are full of antioxidants, calcium, and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in peptic ulcer and H. pylori infection.
  • Avoid sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

Lokit-20 Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Drinking alcohol with Lokit-20 Capsule may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficiency. So, try to avoid or limit alcohol and contact the doctor before intake of Lokit-20 Capsule .

bannner image

Pregnancy

Caution

It is unknown whether Lokit-20 Capsule affects the baby or not. Please consult your doctor before taking Lokit-20 Capsule if you are pregnant or planning to become pregnant. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

bannner image

Breast Feeding

Caution

It is unknown whether Lokit-20 Capsule passes into the breast milk. Please consult your doctor before taking Lokit-20 Capsule if you are breastfeeding. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

bannner image

Driving

Caution

In some cases, Lokit-20 Capsule may cause dizziness, sleepiness, or blurred vision. If you experience these symptoms, refrain from driving or operating heavy machinery until you have fully recovered.

bannner image

Liver

Caution

Lokit-20 Capsule should be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your medical condition.

bannner image

Kidney

Caution

Lokit-20 Capsule should be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your medical condition.

bannner image

Children

Caution

Lokit-20 Capsule should not be given to children under 1 year of age. Lokit-20 Capsule is generally safe to use in children over 1 year when prescribed by a doctor.

Have a query?

FAQs

Lokit-20 Capsule is used to treat gastroesophageal reflux disease (GERD), peptic ulcer (stomach or duodenal ulcer), and Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour).

Lokit-20 Capsule contains omeprazole (a proton pump inhibitor), which helps reduce stomach acid by blocking the action of an enzyme called H+/K+ ATPase (the gastric proton pump). This proton pump lies in the stomach wall cells, is responsible for releasing gastric acid. Lokit-20 Capsule prevents the release of stomach acid and relieves symptoms such as food pipe lining inflammation (esophagitis), acid reflux, or heartburn.

Prolonged intake of Lokit-20 Capsule may lead to atrophic gastritis (inflammation of stomach cells), vitamin B12 deficiency, and weakening of bones or osteoporosis (loss of calcium, magnesium, and vitamin D). Your doctor may prescribe calcium, vitamin D, or haemoglobin-enhancing medications to cope with long-term side effects.

No. Lokit-20 Capsule is not prescribed for stomach cancer. Lokit-20 Capsule is only indicated for the treatment of hyperacidity, acid reflux symptoms (GERD), heartburn and Zollinger-Ellison syndrome.

No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result, stomach acid backflows and enters the upper part of the food pipe, causing heartburn. On the other hand, gas is the result of the digestion of food and drinks, eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc., from the body.

Yes. Lokit-20 Capsule can alter certain medical tests like neuroendocrine tumours (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostic tests, contact your doctor.

No. Lokit-20 Capsule prevents the excessive production of stomach acid, which can cause acid reflux and heartburn. If you notice blood in your stool or mucous, immediately contact the doctor.

Lokit-20 Capsule can be taken with or without food. However, it is recommended to take it 30-60 minutes before a meal, preferably in the morning, for optimal effectiveness.

Yes, you can take Lokit-20 Capsule with domperidone, however it should be taken only of recommended by the doctor.

Before taking any medication, including Lokit-20 Capsule , it's important to consult with a doctor. They can assess your individual needs and provide customised advice. Follow the instructions provided by your healthcare professional and be aware of potential adverse effects. If you have any concerns, don't hesitate to ask for clarification.

Diarrhea is a possible side effect of omeprazole. It's often mild and short-lived, but if it's severe or accompanied by other symptoms, please see your doctor.

The duration of omeprazole treatment is individualised and depends on your specific condition and response to the medication.

Omeprazole can increase the risk of calcium deficiency and osteoporosis if taken for a long time. This is because it can interfere with calcium absorption. If you're taking omeprazole for a long time, talk to your doctor about the risks and benefits.

Yes, long-term use of Lokit-20 Capsule may increase the risk of vitamin deficiencies, particularly vitamin B12. If you have any concerns or face any adverse effects related to vitamin deficiencies, please consult your doctor.

The decision to prescribe omeprazole to cardiac patients should be made on an individual basis, taking into account their medical history and associated risk factors.

Swallow Lokit-20 Capsule as a whole with a glass of water; do not crush, chew, break, or open it.

Lokit-20 Capsule may cause common side effects, such as stomach pain, gas formation (flatulence), nausea, vomiting, diarrhoea, and headache. These side effects are temporary and may resolve themselves over time. However, if the side effects persist or worsen, contact the doctor.

Before taking Lokit-20 Capsule , please inform your doctor about all your medical conditions, sensitivities, and all medications you are currently using. And tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Yes, Lokit-20 Capsule can interact with other medications. It's important to inform your doctor about all the medications you're taking, including prescription medications, over-the-counter drugs and herbal supplements.

Country of origin

India

Manufacturer/Marketer address

Shantisadan, Mirzapur Rd, Ahmedabad, Gujarat 380001
Other Info - LOK0020

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 23, 2025 | 7:35 AM IST

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Reference

  1. https://www.drugs.com/omeprazole.html
  2. https://medlineplus.gov/druginfo/meds/a693050.html
  3. https://assets.hpra.ie/products/Human/19006/Leaflet-2191137-11072017125746-636353746684687500.pdf
  4. https://rwandafda.gov.rw/wp-content/uploads/2023/03/OMLINK-20-Capsules-Omeprazole-USP-20mg-Omeprazole-Pellets-7.15-PIL.pdf
  5. https://www.nps.org.au/assets/medicines/928c8260-b5d1-4989-838e-a53300ff645e.pdf
  6. https://www.drreddys.com/media/109870/omeprazole-20mg-pil.pdf
  7. https://www.nhs.uk/medicines/omeprazole/
  8. https://www.medicines.org.uk/emc/product/663/pil

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