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  3. Lopressor XL 50 Tablet 10's

Lopressor XL 50 Tablet 10's, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Lopressor XL 50 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. This medicine also helps reduce the chances of heart problems such as heart attack and stroke. This medicine suppresses the contraction of blood vessels and promotes smooth blood flow. It also alters the response to nerve impulses in the heart, thereby making the heart pump blood more easily. Common side effects include dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache.

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Composition :

METOPROLOL SUCCINATE-50MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Lopressor XL 50 Tablet

Lopressor XL 50 Tablet is used in the treatment of high blood pressure (hypertension), heart-related chest pain (angina), and irregular heart rhythm (arrhythmia). Hypertension is a lifelong or chronic condition in which the force exerted by the blood against the artery walls becomes so high that it leads to heart disease.

Lopressor XL 50 Tablet contains Metoprolol Succinate, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body.

Not everyone who is taking Lopressor XL 50 Tablet will get these side effects. In some cases, Lopressor XL 50 Tablet may cause certain common side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects are persistent, reach out to your doctor.

You can take Lopressor XL 50 Tablet with food or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.

Inform your doctor if you are allergic to Lopressor XL 50 Tablet . Also, let your doctor know if you have low blood pressure, asthma, an overactive thyroid, metabolic acidosis, or severe blood circulation problems. Consult your doctor before taking Lopressor XL 50 Tablet if you are pregnant or breastfeeding. Lopressor XL 50 Tablet is not recommended for use in children. Lopressor XL 50 Tablet may cause dizziness, so drive with caution.

Uses of Lopressor XL 50 Tablet

Lopressor XL 50 Tablet is used in the treatment of High blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction). The detailed uses of Lopressor XL 50 Tablet are as follows:

  • Treatment of Hypertension: Lopressor XL 50 Tablet controls high blood pressure by reducing the heart rate and the force of contraction, thereby lowering blood pressure.
  • Prevention of Heart-related Chest Pain: Lopressor XL 50 Tablet prevents chest pain (angina) by reducing the workload on the heart and improving blood flow to the heart muscle.
  • Control of Abnormal Heart Rhythms: Lopressor XL 50 Tablet helps manage irregular heartbeats (arrhythmias) by slowing the heart rate and stabilizing the heart's rhythm, reducing symptoms and improving heart function.
  • Management of Heart Attack: Lopressor XL 50 Tablet is used to manage heart attack (myocardial infarction) by reducing the workload on the heart and preventing further damage.

Directions for Use

  • Lopressor XL 50 Tablet can be taken with or without food, or as advised by your doctor.
  • Generally, it is recommended to be taken once daily. Follow your doctor's instructions regarding dosage and timing for optimal results.
  • Swallow Lopressor XL 50 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Lopressor XL 50 Tablet  helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body.
  • This medicine lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.
  • Lopressor XL 50 Tablet may also help in relieving symptoms of migraine-related headache and tremors (fits).

How Lopressor XL 50 Tablet Works

Lopressor XL 50 Tablet contains Metoprolol succinate, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.

Storage

• Store in a cool and dry place away from sunlight. • Keep Lopressor XL 50 Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Lopressor XL 50 Tablet
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Lopressor XL 50 Tablet

Do not take more than the prescribed dose. Overdose of Lopressor XL 50 Tablet may cause nausea, vomiting, decreased consciousness or loss of consciousness (coma), irregular, fast, or slow heartbeat, chest pain, dizziness, fatigue or weakness and fainting. Seek immediate medical help if you suspect that you might have taken an overdose of Lopressor XL 50 Tablet .

Drug Warnings

  • Do not take Lopressor XL 50 Tablet if you are allergic to any component present in Lopressor XL 50 Tablet or any other beta-blockers.
  • Avoid taking Lopressor XL 50 Tablet if you have/had heart conduction, rhythm problems, uncontrolled/severe heart failure, blocked blood vessels, blood circulation problems, untreated pheochromocytoma, metabolic acidosis, low blood pressure, or Prinzmetal angina.
  • Inform your doctor if you have asthma, COPD, diabetes, blood vessel disorder, slow heart rate, pheochromocytoma, myasthenia gravis, dry eye problems, kidney or liver impairment; if you are taking anti-depressants, other blood pressure-lowering medicines, or anti-arrhythmic agents.
  • Consult your doctor before taking Lopressor XL 50 Tablet if you are pregnant or breastfeeding.
  • Lopressor XL 50 Tablet is not recommended for children as safety and efficacy have not been established.
  • Lopressor XL 50 Tablet may cause dizziness, so drive with caution.
  • Don't stop taking Lopressor XL 50 Tablet without consulting your doctor. Suddenly stopping the use of Lopressor XL 50 Tablet may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will gradually lower your dose to help prevent these symptoms.

Drug-Drug Interactions

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MetoprololSaquinavir
Severe
MetoprololAcebutolol
Severe

Drug-Drug Interactions

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MetoprololSaquinavir
Severe
How does the drug interact with Lopressor XL 50 Tablet:
Using Lopressor XL 50 Tablet and Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possible interaction between Lopressor XL 50 Tablet and Saquinavir, but they can be taken together if your doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, slow pulse, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololAcebutolol
Severe
How does the drug interact with Lopressor XL 50 Tablet:
Coadministration of Acebutolol with Lopressor XL 50 Tablet can cause abnormal heart rhythm.

How to manage the interaction:
Taking Lopressor XL 50 Tablet and Acebutolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololElvitegravir
Severe
How does the drug interact with Lopressor XL 50 Tablet:
Taking elvitegravir may increase the metabolism of Lopressor XL 50 Tablet.

How to manage the interaction:
Although there may be an interaction, Lopressor XL 50 Tablet can be taken with Elvitegravir if prescribed by the doctor. Consult the doctor if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medications without talking to your doctor.
MetoprololTizanidine
Severe
How does the drug interact with Lopressor XL 50 Tablet:
Coadministration of Lopressor XL 50 Tablet and Tizanidine may reduce the efficiency of Lopressor XL 50 Tablet.

How to manage the interaction:
Taking Lopressor XL 50 Tablet and Tizanidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. do not discontinue any medications without talking to your doctor.
MetoprololClonidine
Severe
How does the drug interact with Lopressor XL 50 Tablet:
Co-administration of Clonidine and Lopressor XL 50 Tablet may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Lopressor XL 50 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
MetoprololCeritinib
Severe
How does the drug interact with Lopressor XL 50 Tablet:
Taking ceritinib together with Lopressor XL 50 Tablet can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Lopressor XL 50 Tablet and Ceritinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololVerapamil
Severe
How does the drug interact with Lopressor XL 50 Tablet:
Coadministration of Lopressor XL 50 Tablet with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Lopressor XL 50 Tablet can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
MetoprololDiltiazem
Severe
How does the drug interact with Lopressor XL 50 Tablet:
Coadministration of Lopressor XL 50 Tablet with Diltiazem can increase the side effects.

How to manage the interaction:
Although there is a possible interaction between Lopressor XL 50 Tablet and Diltiazem, you can take these medicines together if prescribed by your doctor. Consult your doctor immediately if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololAminophylline
Severe
How does the drug interact with Lopressor XL 50 Tablet:
Coadministration of Aminophylline with Lopressor XL 50 Tablet together can make Lopressor XL 50 Tablet less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Lopressor XL 50 Tablet may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololAtazanavir
Severe
How does the drug interact with Lopressor XL 50 Tablet:
Use of Lopressor XL 50 Tablet with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Lopressor XL 50 Tablet and Atazanavir, it can be taken if prescribed by the doctor. Consult the doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy body weight, ideally with a BMI between 18.5 and 24.9, as excess weight increases the risk of high blood pressure and heart disease.
  • Engage in regular physical activity, aiming for at least 150 minutes of moderate-intensity exercise per week (e.g., brisk walking, cycling, swimming) to help lower blood pressure by about 5–8 mmHg.
  • Limit sodium intake to ≤2300 mg per day, with an ideal goal of 1500 mg daily for adults with high blood pressure or heart problems.
  • If you drink alcohol, limit intake to up to 1 drink per day for women and up to 2 drinks per day for men, as excessive drinking can raise blood pressure.
  • Quit smoking, as it significantly increases the risk of heart attack, stroke, and complications from high blood pressure.
  • Manage stress through relaxation techniques, deep breathing, mindfulness, adequate sleep, and spending time with loved ones to help maintain stable blood pressure levels.
  • Monitor blood pressure regularly at home and keep a record. Contact your doctor promptly if you notice frequent or large fluctuations.
  • Eat a heart-healthy diet, rich in fruits, vegetables, whole grains, lean protein, and omega-3 fatty acids (from fish, flaxseeds, or walnuts) to support cardiovascular health.
  • Use healthy cooking oils such as olive, canola, or soybean oil, and limit saturated fats to help manage blood pressure and improve heart health.
  • Follow your doctor’s advice strictly regarding medications, diet, and lifestyle adjustments to reduce the risk of severe heart complications.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Lopressor XL 50 Tablet Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

Alcohol might increase the blood pressure-lowering effect of Lopressor XL 50 Tablet . It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking Lopressor XL 50 Tablet .

bannner image

Pregnancy

Unsafe

Lopressor XL 50 Tablet belongs to pregnancy category C. Lopressor XL 50 Tablet is not recommended for use during pregnancy. If you are pregnant, think you are pregnant or planning for pregnancy, consult your doctor.

bannner image

Breast Feeding

Caution

Lopressor XL 50 Tablet may pass into breastmilk. Consult a doctor before taking Lopressor XL 50 Tablet if you are breastfeeding.

bannner image

Driving

Caution

Lopressor XL 50 Tablet may cause dizziness and tiredness. Therefore, drive or operate machinery only if you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Lopressor XL 50 Tablet if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Lopressor XL 50 Tablet if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Lopressor XL 50 Tablet is not recommended in children as the safety and efficacy have not been established.

Have a query?

FAQs

Lopressor XL 50 Tablet is used to treat high blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction).

Lopressor XL 50 Tablet helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. Thereby, lowers blood pressure.

High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Lopressor XL 50 Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.

Do not stop taking Lopressor XL 50 Tablet without consulting your doctor, as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Lopressor XL 50 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Lopressor XL 50 Tablet .

Consult your doctor before taking Lopressor XL 50 Tablet if you have hyperthyroidism (overactive thyroid) as it might mask the symptoms or make it difficult to recognise the signs of thyrotoxicosis (excess thyroid hormone in the body).

Consult your doctor before taking Lopressor XL 50 Tablet with anti-diabetic medicines as it might mask the signs of low blood sugar. Regular monitoring of blood glucose levels while taking Lopressor XL 50 Tablet is advised.

Your doctor may probably ask you to stop taking Lopressor XL 50 Tablet 24hours prior to the surgery, as it might lower blood pressure when combined with general anaesthesia. If you are due to have any surgery or are receiving an anaesthetic, inform the doctor that you are taking Lopressor XL 50 Tablet .

Taking Lopressor XL 50 Tablet along with multivitamin/multimineral supplements may decrease the effect of Lopressor XL 50 Tablet . Therefore, maintain a gap of at least 2hours between both. However, you are advised to take Lopressor XL 50 Tablet with other medicines only after consulting your doctor.

Yes, Lopressor XL 50 Tablet is a selective beta-blocker, that acts on the heart muscles.

No, do not stop taking Lopressor XL 50 Tablet if your blood pressure level comes in control as discontinuing suddenly may worsen the condition. Therefore, continue taking Lopressor XL 50 Tablet for long as it is advised by your doctor.

No, Lopressor XL 50 Tablet is not a blood thinner. Lopressor XL 50 Tablet relaxes the blood vessels, and slows down the heart rate. Thereby, it reduces the workload on the heart and makes it easier to pump blood effectively.

The time taken by Lopressor XL 50 Tablet to start working varies from person to person. Usually, it starts working within 15 minutes. However, it may take up to 2 hours to start working in some people. The maximum or full effect is usually achieved within 1 week as it starts acting slowly. In case you do not feel any difference while taking Lopressor XL 50 Tablet , do not worry. It exerts its beneficial effects when taken for a long time.

The side effects of Lopressor XL 50 Tablet include stomach pain, nausea, diarrhoea, dizziness, tiredness or headache. If these side effects persist or worsen, please consult your doctor.

Lopressor XL 50 Tablet is generally safe if used as prescribed by the doctor. If this medication is stopped suddenly, it may cause harmful effects such as a sudden increase in the heart rate and affect its activity, which can be dangerous for heart failure patients and in some cases even result in a heart attack. Therefore, take Lopressor XL 50 Tablet for the prescribed duration and do not stop taking it suddenly.

Lopressor XL 50 Tablet belongs to the class of medicines called beta-blockers. Though their effect on sleep differs from person to person, it has been found that these medications are known to change the sleep pattern and disturb sleep in some patients. On the other hand, it has also been observed to promote better sleep in patients with increased anxiety and heart rate by calming down the nerves and heart. If you have any sleep disturbances, please consult your doctor.

No, you are recommended to avoid alcohol consumption after taking Lopressor XL 50 Tablet as alcohol might increase the blood pressure-lowering effect of Lopressor XL 50 Tablet and might cause increased dizziness.

Country of origin

INDIA

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - LOP0028

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 5, 2025 | 8:51 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/metoprolol.html
  2. https://www.nhs.uk/medicines/metoprolol/
  3. https://www.medicines.org.uk/emc/files/pil.5816.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/019962s032lbl.pdf

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