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Lox 2% Injection 2 ml is used as local anaesthesia. It works by inhibiting the transmission of pain sensations from the nerves to the brain. In some cases, this medicine may cause side effects such as injection site reactions (itching, irritation, burning or redness). Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lox 2% Injection 2 ml

Lox 2% Injection 2 ml is a sterile injection used by healthcare professionals to produce temporary numbness in specific areas of the body before minor surgeries, dental work, or medical tests. It is also utilized in emergency clinical settings to treat serious heart rhythm disturbances (ventricular arrhythmias).

Because this medication is injected directly by a healthcare provider, it is typically given as a single dose or short-term infusion tailored to your specific procedure. You do not need to take it on a regular daily schedule at home. Your doctor will advise you on temporary dietary restrictions, such as avoiding hot foods or chewing until local numbness wears off.

Most patients experience only mild, temporary reactions such as minor redness, swelling, or a tingling sensation around the injection area. However, you must inform your medical team immediately if you experience dizziness, confusion, breathing difficulties, or an uneven heartbeat during or after the procedure.

Do not receive this injection if you have severe heart blocks or a known allergy to local anesthetics. It is vital to tell your doctor before receiving Lox 2% Injection 2 ml   if you have liver damage, kidney disease, or a history of heart failure.

This injection can interact with certain heart medications or beta-blockers, which can lead to an excessively slow heart rate. If you are pregnant, breastfeeding, or caring for an elderly patient, discuss the safety of this injection with your doctor or pharmacist before the procedure.

Uses of Lox 2% Injection 2 ml

Lox 2% Injection 2 ml is used to provide temporary local anaesthesia by numbing the treatment area, helping reduce pain and discomfort during minor medical procedures while maintaining an appropriate solution for safe administration.

  • Local anesthesia: It numbs specific tissues to prevent pain during minor surgical procedures, dental work, or diagnostic tests.
  • Nerve block: It temporarily stops pain transmission along specific nerve pathways to relieve localized severe pain or prepare for regional surgical procedures.
  • Ventricular arrhythmias: In emergency situations, it is injected intravenously to help restore a normal, steady heartbeat during dangerous cardiac events.

Key Benefits

Lox 2% Injection 2 ml provides rapid local anaesthesia to minimize pain during medical procedures, while the sodium chloride solution helps ensure compatibility with body tissues and supports safe administration.

  • Provides Rapid Pain Relief: Lidocaine quickly numbs the treatment area, reducing pain and discomfort during minor surgical, diagnostic, or dental procedures.
  • Improves Patient Comfort: By blocking pain signals from the nerves, it helps make procedures more comfortable and less stressful.
  • Allows Procedures Without General Anaesthesia: Enables many minor procedures to be performed safely under local anaesthesia, reducing the need for general anaesthesia.
  • Supports Safe Drug Administration: Sodium chloride creates an isotonic solution that is gentle on tissues and suitable for injection or irrigation.
  • Promotes Accurate Medical Procedures: Effective local numbing helps patients remain still and comfortable, allowing healthcare professionals to perform procedures more efficiently and precisely.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Lox 2% Injection 2 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Lox 2% Injection 2 ml Works

Lox 2% Injection 2 ml contains two ingredients lidocaine and sodium chloride that work together to provide effective local anesthesia. Lidocaine blocks voltage-gated sodium channels in nerve cells, temporarily preventing the generation and transmission of pain signals. When administered intravenously for ventricular arrhythmias, it also blocks sodium channels in cardiac tissue, helping stabilize abnormal electrical activity in the ventricles. Lidocaine temporarily prevents nerves from sending pain messages to the brain, causing numbness in the treated area during medical or surgical procedures.lidocaine stabilises the heart's electrical activity (sodium channel blockade in cardiac tissue) when used for arrhythmias. Sodium chloride acts as a sterile isotonic solution that serves as the vehicle for lidocaine. It helps maintain compatibility with body tissues and allows safe preparation and administration of the injection. It does not contribute to the anaesthetic effect.It matches the body's natural salt balance, making the injection stable, compatible with body tissues, and less likely to cause irritation at the injection site.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Lox 2% Injection 2 ml. Alcohol intake, along with Lox 2% Injection 2 ml, may cause increased drowsiness.

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Pregnancy

Unsafe

It is not recommended to take Lox 2% Injection 2 ml while you are pregnant. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe you Lox 2% Injection 2 ml only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether breastfeeding mothers can take Lox 2% Injection 2 ml or not.

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Driving

Caution

Lox 2% Injection 2 ml may cause numbness in certain areas of the body. Hence, avoid driving and using machines that require alertness.

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Liver

Caution

Dose adjustment may be needed. Lox 2% Injection 2 ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Lox 2% Injection 2 ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Lox 2% Injection 2 ml should not be used for children less than one month, as the efficacy and safety have not been established.

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Heart

Caution

Lox 2% Injection 2 ml should be administered with caution, especially if you have a history of heart problems. Please inform your doctor about any existing heart problems before receiving Lox 2% Injection 2 ml.

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Geriatrics

Caution

Lox 2% Injection 2 ml should be administered with caution in elderly patients due to an increased risk of side effects. Dose adjustment may be required based on their health condition.

What if I have taken an overdose of Lox 2% Injection 2 ml

Overdoses are extremely rare because the injection is prepared and given by trained medical professionals. However, if you suspect an overdose or notice signs like extreme drowsiness, breathing problems, confusion, or a very slow heart rate after your procedure, seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Avoid Eating Until Numbness Wears Off: Avoid eating, drinking, or chewing gum if you had an injection in your mouth or throat until the numbness has completely worn off to prevent accidentally biting your cheek or choking.
  • Keep the Injection Site Clean: Keep the area around the injection clean and dry to minimize the risk of localized skin irritation or infection.
  • Rest the Treated Area: Avoid strenuous physical activity or lifting heavy objects if you received a joint or muscle injection, allowing the treated area adequate time to recover.
  • Limit Alcohol Intake: Limit or avoid alcohol before and after your procedure, as it can interfere with how your body processes anaesthetics and may slow your recovery.
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How Soon It Starts Working

The time required for Lox 2% Injection 2 ml to start to work: The time required for Lox 2% Injection 2 ml to show its action is unknown. The time for which the effects of Lox 2% Injection 2 ml last: The duration of action for Lox 2% Injection 2 ml is clinically unknown.

What if you forget to take Lox 2% Injection 2 ml

Since this medication is injected only during specific medical procedures by a healthcare provider, missing a scheduled dose is highly unlikely.

Storage

•Store Lox 2% Injection 2 ml at controlled room temperature between 20°C to 25°C (68°F to 77°F). •Keep the product in its original outer packaging to protect it from direct light.

Drug Warnings

  • Check the Solution Before Use: Ensure the healthcare professional inspects the solution before injection. It should be completely clear, colorless, and free from visible particles.
  • Report Unusual Pain Immediately: Tell your doctor immediately if you experience a sharp, shooting pain or an intense burning sensation during the injection.
  • Avoid Manipulating the Injection Site: Do not rub, massage, or apply heat to the injection site after the procedure unless specifically instructed by your healthcare provider.
  • Wait Until the Anaesthetic Wears Off: Avoid driving, operating machinery, or performing tasks requiring full alertness until the effects of the anaesthetic have completely worn off.
  • Ensure Sterile Injection Practices: Confirm that your healthcare team uses a sterile, single-use needle and syringe for your injection.
  • Who Should Not Receive This Injection: Do not use Lox 2% Injection 2 ml  if you are allergic to lidocaine or other amide-type local anaesthetics, have had a serious reaction to local anaesthetic injections, or have certain severe heart conduction disorders unless advised by your healthcare provider. 

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Beta-blockers and other heart medications: May increase the risk of a slow or irregular heartbeat.
  • Other local anaesthetics: May increase the risk of systemic toxicity when used together.
LidocaineArbutamine
Critical
LidocaineSaquinavir
Critical

Drug-Drug Interactions

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LidocaineArbutamine
Critical
How does the drug interact with Lox 2% Injection 2 ml:
Taking Lox 2% Injection 2 ml and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Lox 2% Injection 2 ml with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineSaquinavir
Critical
How does the drug interact with Lox 2% Injection 2 ml:
Taking Lox 2% Injection 2 ml with Saquinavir can increase the blood levels of Lox 2% Injection 2 ml and cause an irregular heart rhythm.

How to manage the interaction:
Taking Lox 2% Injection 2 ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lox 2% Injection 2 ml:
Taking Lox 2% Injection 2 ml with Cyclophosphamide may increase the risk of methemoglobinemia (a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Although there is a possible interaction, cyclophosphamide can be taken with Lox 2% Injection 2 ml if prescribed by the doctor. However, consult the doctor if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Lox 2% Injection 2 ml:
Taking phenazopyridine with Lox 2% Injection 2 ml can increase the risk of methemoglobinemia(a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Co-administration of Phenazopyridine with Lox 2% Injection 2 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
LidocaineIomeprol
Severe
How does the drug interact with Lox 2% Injection 2 ml:
Taking Lox 2% Injection 2 ml and Iomeprol may increase the risk of causing seizures(fits).

How to manage the interaction:
There may be a possibility of interaction between Lox 2% Injection 2 ml and Iomeprol, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lox 2% Injection 2 ml:
Taking Lox 2% Injection 2 ml with Trimethoprim may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Trimethoprim with Lox 2% Injection 2 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience, gray skin color, feeling sick, having a headache, feeling dizzy or lightheaded, feeling tired, having trouble breathing, a fast or irregular heartbeat, feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
LidocaineFosamprenavir
Severe
How does the drug interact with Lox 2% Injection 2 ml:
Taking Lox 2% Injection 2 ml and Fosamprenavir may increase the blood levels of Lox 2% Injection 2 ml, which increases the risk of serious side effects.

How to manage the interaction:
Although taking Lox 2% Injection 2 ml and Fosamprenavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LidocaineAmprenavir
Severe
How does the drug interact with Lox 2% Injection 2 ml:
Taking Lox 2% Injection 2 ml with Amprenavir may increase the blood levels of Lox 2% Injection 2 ml, which increases severe side effects.

How to manage the interaction:
There may be a possibility of interaction between Lox 2% Injection 2 ml and Amprenavir, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Lox 2% Injection 2 ml:
Taking Lox 2% Injection 2 ml with Bupivacaine may cause serious side effects including methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells), brain related problems and heart problems.

How to manage the interaction:
There may be a possibility of interaction between Lox 2% Injection 2 ml and Bupivacaine, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop pale, gray, or blue colored skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lox 2% Injection 2 ml:
Taking Lox 2% Injection 2 ml with phenobarbital may increase the risk of methemoglobinemia(blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking phenobarbital and Lox 2% Injection 2 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Lox 2% Injection 2 ml when used as directed. 

 

No clinically significant drug interactions are known with Lox 2% Injection 2 ml when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[VASOPRESSORS]

FAQs

Lox 2% Injection 2 ml is used to induce local anaesthesia.
Lox 2% Injection 2 ml contains two medicines namely lidocaine and sodium chloride. Lidocaine (local anaesthetic) works by stopping pain indications from the nerves to the brain. Hence, it gives an anaesthetic effect and helps decrease the sensation of pain. Sodium chloride is a distilled salt solution that helps avoid edema (swelling) and irritation on injection.
Lox 2% Injection 2 ml is used in the emergency treatment of cardiac arrest, arrhythmia (irregular heartbeats), or other severe heart conditions.
The most common side effects of Lox 2% Injection 2 ml are wheeziness, swelling of the eyelids, lips, or face, difficulty in breathing, dizziness, rash, or itching (especially affecting your whole body). Most of these side effects of Lox 2% Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Difficulty walking after spinal anaesthetic could be due to neurological complications like nerve damage. If you experience any difficulty in walking after a spinal anaesthesia contact your doctor for guidance.
Lox 2% Injection 2 ml should not be given to people who are allergic to any of its components or have certain health conditions like low blood volume, low blood pressure, or slow heart rate. It's also not recommended for babies under 1 month old. If you're pregnant or breastfeeding, be sure to tell your doctor before using Lox 2% Injection 2 ml.
No, Lox 2% Injection 2 ml doesn’t have the potential to habit forming or abuse when used exactly as prescribed by your doctor.
Lox 2% Injection 2 ml is typically used as a local anaesthetic for short-term pain relief, and long-term use is not common. If you're concerned about potential long-term side effects, consult your doctor or healthcare professional.
Lox 2% Injection 2 ml doesn’t have the potential to cause constipation. However, if you have constipation please consult your doctor.
Yes, Lox 2% Injection 2 ml is safe when used under a doctor’s supervision. However, it may cause some side effects like wheeziness, swelling of the eyelids, lips, or face, difficulty in breathing, and rash or itching. If any of these side effects persist or worsen consult your doctor immediately.
Lox 2% Injection 2 ml is not known to cause dental issues. However, let the doctor know if you have dental fixtures before starting Lox 2% Injection 2 ml.
Store Lox 2% Injection 2 ml in a cool, dry place away from direct sunlight and out of the reach of children. Do not use it after the expiry date printed on the package.
Avoid driving until the numbness has completely worn off and you feel fully alert. If you received a large dose or a nerve block, arrange for someone else to drive you home.
You may feel a brief pinch or stinging sensation when the needle is inserted or the medicine is injected. The area quickly becomes numb, reducing further pain.
It should only be given to pregnant women if the benefits outweigh the risks. Talk to your doctor to understand the safety steps for your situation.
Mild tenderness is normal, but if you notice increasing pain, severe redness, heat, or pus at the injection site, contact your doctor right away as these may be signs of infection.
Yes, but your medical team will monitor your blood pressure closely during the procedure. Talk to your doctor if you have any pre-existing heart conditions.
You should wait to eat or drink hot liquids until the numbness has completely gone to avoid accidentally biting your tongue or burning your mouth.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - LOX0030
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