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compositionComposition:HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MG
prescription
Prescription Medicine
info
Lsrh Tablet 10's
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MG

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lsrh Tablet

Lsrh Tablet is a prescription medication used to manage high blood pressure (hypertension). It is also prescribed to lower the risk of stroke in patients who have both high blood pressure and an enlarged heart.

For the best results, you must take this medication consistently every day, exactly as your doctor directs. It is typically taken once daily, either with or without food. Along with taking your medicine, adopting lifestyle changes such as eating a low-salt diet and exercising regularly can greatly improve your blood pressure control.

While taking Lsrh Tablet , you may experience some mild side effects like dizziness or fatigue as your body adjusts. However, you should contact your doctor immediately if you experience serious side effects, such as a severe allergic reaction, muscle weakness, or a rapid, irregular heartbeat.

Before starting Lsrh Tablet , tell your doctor if you have kidney disease, liver damage, diabetes, or gout. Do not take this medicine if you are pregnant, as it can cause serious harm or death to an unborn baby. It should also be avoided by individuals who are unable to pass urine.

This medication can interact with other drugs, including potassium supplements, lithium, and certain pain relievers, which can alter how the medicine works. If you are breastfeeding or are an older adult, talk to your doctor or pharmacist to ensure this medication is safe for your specific situation.

Uses of Lsrh Tablet

Lsrh Tablet is used to manage high blood pressure and reduce the risk of certain cardiovascular complications.

  • Hypertension (High Blood Pressure): Lsrh Tablet helps lower blood pressure by relaxing blood vessels and removing excess fluid from the body. This reduces strain on the heart and blood vessels and helps prevent long-term damage to organs such as the heart, brain, and kidneys.
  • Stroke Risk Reduction: In people with high blood pressure and left ventricular hypertrophy (enlargement of the heart's left pumping chamber), this medication helps reduce the risk of stroke.

Key Benefits

Lsrh Tablet provides effective blood pressure control and long-term cardiovascular protection.

  • Helps control blood pressure: By lowering elevated blood pressure, the medication reduces the strain placed on the heart and blood vessels.
  • Reduces the risk of cardiovascular complications: Maintaining healthy blood pressure levels can help lower the risk of heart attacks, strokes, and other serious cardiovascular events.
  • Supports kidney health: Good blood pressure control helps protect the kidneys from damage associated with long-standing hypertension.
  • Provides the convenience of combination therapy: Combining two blood pressure-lowering medicines into a single tablet simplifies treatment and may improve medication adherence.
  • Offers continuous cardiovascular protection: Even when high blood pressure causes no noticeable symptoms, regular use helps provide ongoing protection against long-term complications.
  • Promotes long-term health and wellbeing: Consistent blood pressure management can help maintain overall physical health and support an active lifestyle.
Side effects of Lsrh Tablet
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.

Directions for Use

To achieve the best blood pressure control, take Lsrh Tablet exactly as prescribed by your doctor.

  • Swallow the tablet whole with a glass of water.
  • Do not crush, chew, or break the tablet unless advised otherwise by your doctor.
  • You can take this medicine with or without food.
  • Try to take it at the same time each day to help maintain a consistent level of the medication in your body.
  • If prescribed once daily, it is often recommended to take the medicine in the morning, as the diuretic component may increase urination and disrupt sleep if taken late in the day.
  • Follow your doctor's instructions regarding the dose and duration of treatment.
  • Do not stop taking the medication or change your dose without consulting your doctor, even if you feel well.

How Lsrh Tablet Works

Lsrh Tablet contains losartan and hydrochlorothiazide, which work together to lower high blood pressure and reduce strain on the heart and blood vessels. Losartan is an angiotensin receptor blocker (ARB) that works by blocking the action of a natural hormone called angiotensin II, which normally causes blood vessels to tighten and narrow. By blocking this effect, losartan helps blood vessels relax and widen, allowing blood to flow more easily and lowering blood pressure. Hydrochlorothiazide is a diuretic, commonly known as a 'water pill,' that helps the kidneys remove excess salt and water from the body through urine. This reduces the amount of fluid circulating in the bloodstream, which helps lower blood pressure and decreases the workload on the heart. Together, these medicines help improve blood flow, control high blood pressure, and reduce the risk of complications such as heart attack, stroke, and kidney problems.
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Alcohol

Unsafe

You are recommended not to consume alcohol and Lsrh Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

Lsrh Tablet is not recommended during pregnancy as it may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Consult your doctor

Lsrh Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this.

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Driving

Unsafe

Lsrh Tablet causes drowsiness and dizziness, so drive only if you are alert.

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Liver

Caution

Lsrh Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will adjust the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Unsafe

Lsrh Tablet is not recommended in patients with chronic kidney disease (severe renal impairment). Safety and effectiveness in patients with severe renal impairment have not been established.

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Children

Unsafe

Lsrh Tablet is not recommended for use in children below 18 yaers of age as the safety and efficacy are not established.

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Heart

Safe if prescribed

Lsrh Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Lsrh Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Lsrh Tablet

Do not take more than the prescribed dose of Lsrh Tablet as it may cause overdose. The symptoms of overdose include sleepiness, papitations (pounding heartbeat) and dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Reduce Salt Intake: Limit your consumption of high-sodium foods, processed meats, and canned soups, as excess salt directly counteracts the effects of this medication.
  • Stay Hydrated: Drink an adequate amount of water daily. However, because this medicine contains a diuretic, ask your doctor for specific fluid intake guidelines that suit your health status.
  • Be Mindful of Potassium: Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor, as one of the active components can raise potassium levels in your blood.
  • Limit Alcohol: Avoid or significantly limit alcohol consumption. Alcohol can interact with Lsrh Tablet to cause a sudden, sharp drop in blood pressure, leading to severe dizziness or fainting.

Have a query?

How Soon It Starts Working

The time required for Lsrh Tablet to start to work: Lsrh Tablet ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Lsrh Tablet last: The effect of Lsrh Tablet lasts for 24 hours.

What if you forget to take Lsrh Tablet

If you miss a dose of Lsrh Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Lsrh Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Pregnancy Warning: Do not take this medication if you are pregnant or planning to become pregnant. If you suspect you are pregnant, stop taking the medication immediately and contact your doctor, as it can cause serious injury to an unborn baby.
  • Rise Slowly: To minimise the risk of dizziness or fainting, take your time when rising from a lying or sitting position.
  • Regular Lab Tests: Your doctor will likely schedule regular blood tests to monitor your kidney function and check the levels of electrolytes (like potassium and sodium) in your blood.
  • Sun Sensitivity: This medicine can make your skin more sensitive to sunlight. Wear protective clothing and apply sunscreen when spending time outdoors.

Drug-Drug Interactions

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Drug-Drug Interactions

Lsrh Tablet may interact with several medications that affect blood pressure, kidney function, or electrolyte balance.

  • Potassium supplements or potassium-sparing diuretics: Using these with Lsrh Tablet may increase potassium levels in the blood, which can become dangerously high.
  • Lithium: This medication may increase lithium levels in the bloodstream, raising the risk of lithium toxicity.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen: These medicines may reduce the blood pressure-lowering effects of Lsrh Tablet and increase the risk of kidney problems.
  • Other blood pressure medications: Combining multiple antihypertensive medicines may cause blood pressure to fall too low, resulting in dizziness, light-headedness, or fainting.


Drug-Food Interactions

Certain foods and beverages may influence the safety and effectiveness of Lsrh Tablet .

  • Potassium-containing salt substitutes: These products may increase blood potassium levels and should be used cautiously or avoided unless recommended by your doctor.
  • Alcohol: Drinking alcohol while taking this medication may enhance its blood pressure-lowering effect, increasing the risk of dizziness and falls.


Drug-Disease Interactions

Certain medical conditions may require closer monitoring or dose adjustments during treatment.

  • Kidney disease: Reduced kidney function may affect how the medication is processed and increase the risk of electrolyte imbalances or kidney-related side effects.
  • Liver disease: Liver impairment can alter the way the body handles this medication and may increase the risk of adverse effects.
  • Gout: The hydrochlorothiazide component can increase uric acid levels, which may trigger or worsen gout attacks.
  • Diabetes: This medication may affect blood glucose control, and people with diabetes may require closer monitoring of their blood sugar levels during treatment.
Losartan + HydrochlorothiazideDofetilide
Critical
Losartan + HydrochlorothiazideCisapride
Critical

Drug-Drug Interactions

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Losartan + HydrochlorothiazideDofetilide
Critical
How does the drug interact with Lsrh Tablet:
Taking Dofetilide and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Combining Dofetilide and Hydrochlorothiazide together can result in an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Losartan + HydrochlorothiazideCisapride
Critical
How does the drug interact with Lsrh Tablet:
Taking Cisapride and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Hydrochlorothiazide together can result in an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Losartan + HydrochlorothiazideDronedarone
Severe
How does the drug interact with Lsrh Tablet:
Co-administration of Dronedarone and Hydrochlorothiazide can increase the risk of severe irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dronedarone and Hydrochlorothiazide can result in an interaction, it can be taken if a doctor advises. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.
Losartan + HydrochlorothiazideAmiodarone
Severe
How does the drug interact with Lsrh Tablet:
Coadministration of Amiodarone together with Hydrochlorothiazide may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Hydrochlorothiazide interact, they can be used if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.
Losartan + HydrochlorothiazideZiprasidone
Severe
How does the drug interact with Lsrh Tablet:
Taking Ziprasidone and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Ziprasidone and Hydrochlorothiazide together can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
Losartan + HydrochlorothiazideEnalapril
Severe
How does the drug interact with Lsrh Tablet:
Using enalapril together with losartan may increase the risk of side effects (low blood pressure, kidney function impairment, and a condition called hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking Enalapril with Losartan may result in an interaction, they can be taken together if a doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medication without consulting a doctor.
Losartan + HydrochlorothiazidePerindopril
Severe
How does the drug interact with Lsrh Tablet:
Taking Losartan with Perindopril may increase the risk of side effects (low blood pressure, kidney problems, and increased potassium levels in the blood).

How to manage the interaction:
Taking Losartan with Perindopril together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Losartan + HydrochlorothiazidePotassium citrate
Severe
How does the drug interact with Lsrh Tablet:
Coadministration of Losartan with Potassium citrate can increase potassium levels, which can lead to severe conditions like kidney failure, and irregular heart rhythm.

How to manage the interaction:
Taking Losartan with Potassium citrate together can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Losartan + HydrochlorothiazideAminolevulinic acid
Severe
How does the drug interact with Lsrh Tablet:
Coadministration of Aminolevulinic acid with Hydrochlorothiazide can make your skin more sensitive to bright lights. This could increase the risk or severity of developing a sunburn.

How to manage the interaction:
Although there is a possible interaction between Aminolaevulinic acid and Hydrochlorothiazide, it can be taken if advised by a doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Do not stop using any medications without a doctor's advice.
Losartan + HydrochlorothiazidePimozide
Severe
How does the drug interact with Lsrh Tablet:
The combined use of Pimozide and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Pimozide and Hydrochlorothiazide together can result in an interaction, but it can be taken if advised by a doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MGPotassium rich foods, Fruit juices
Moderate

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MGPotassium rich foods, Fruit juices
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Grapefruit Juice

How to manage the interaction:
Coadministration of potassium-containing salt substitutes with Lsrh Tablet may cause high levels of potassium in blood. Also, coadministration of grapefruits and grapefruit juice with Lsrh Tablet may decrease the efficacy of losartan. Avoid consumption of potassium-containing salt substitutes, grapefruits and grapefruit juice while being treated with Lsrh Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Lsrh Tablet is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure.

Lsrh Tablet is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload).

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend to discontinue it.

Lsrh Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.

In case you have missed a dose of Lsrh Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both the doses together. Take only one dose; taking a double dose of Lsrh Tablet will lead to low blood pressure.

Yes, prolonged intake of Lsrh Tablet can cause an increase in blood potassium level. So, patients taking Lsrh Tablet should avoid taking supplements and food rich in potassium to avoid any unpleasant side-effect.

Yes, Lsrh Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Lsrh Tablet . In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.

You should not take Lsrh Tablet if you have ever had liver disease, kidney failure, glaucoma, high or low levels of magnesium or potassium in your blood, have allergies or asthma, lupus (an autoimmune disease), diabetes, anuria (reduction or absence of urine) and pregnant women in their second or third trimesters. Besides this, avoid using Lsrh Tablet (in case of diabetes) with aliskiren (a blood pressure medicine) as it can lead to a life-threatening condition.

No, you should not take this medicine if you are pregnant. It carries a high risk of causing severe injury or death to an unborn baby. If you become pregnant while taking it, contact your doctor immediately. Talk to your doctor for safer alternative treatments.

It is generally recommended to take this medication in the morning. Because it contains a diuretic, taking it later in the day or close to bedtime may cause you to wake up during the night to urinate. Talk to your doctor for personalized advice.

Yes, one of the active components is a diuretic, which helps your body get rid of excess water and salt. You will likely notice an increase in urination, especially when you first start taking the medicine. Talk to your doctor if this becomes bothersome.

You should avoid or limit alcohol while taking this medicine. Alcohol can compound the blood-pressure-lowering effect, which can make you feel extremely dizzy, lightheaded, or prone to fainting. Talk to your doctor about safe alcohol limits.

You should avoid potassium supplements and salt substitutes containing potassium unless your doctor specifically tells you otherwise. While one component helps eliminate potassium, the other helps retain it, so balance is crucial. Talk to your doctor or pharmacist about your dietary needs.

You may see a reduction in your blood pressure within a few days, but it can take up to 3 to 4 weeks of consistent use to achieve the full beneficial effect. Do not stop taking the medicine if you do not see immediate results. Talk to your doctor if you have concerns.

If you feel dizzy, sit or lie down immediately to prevent fainting or falling. Avoid driving or operating machinery while feeling this way, and make sure to rise slowly from sitting or lying positions. If the dizziness persists, talk to your doctor.

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Country of origin

INDIA
Other Info - LSR0001

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