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  3. LUPIGEST 100MG TABLET

LUPIGEST 100MG TABLET, Pack of 10 TABLETS
LUPIGEST 100MG TABLET, Pack of 10 TABLETS
LUPIGEST 100MG TABLET, Pack of 10 TABLETS
LUPIGEST 100MG TABLET, Pack of 10 TABLETS
LUPIGEST 100MG TABLET, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

LUPIGEST 100MG TABLET is used to treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour. It contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body. This medicine may sometimes cause side effects such as dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes or constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

PROGESTERONE-100MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About LUPIGEST 100MG TABLET

LUPIGEST 100MG TABLET is used in combination with oestrogen for hormone replacement therapy. Besides this, LUPIGEST 100MG TABLET also treats amenorrhoea (absence of menstrual periods) and prevents endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour. Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

LUPIGEST 100MG TABLET contains progesterone, which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

You are advised to take LUPIGEST 100MG TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. Most of these side effects of LUPIGEST 100MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to soya, LUPIGEST 100MG TABLET or any other medicines, please tell your doctor. Avoid taking LUPIGEST 100MG TABLET if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking LUPIGEST 100MG TABLET if you are pregnant, as it may harm the unborn baby. You are advised to use effective birth control methods while taking LUPIGEST 100MG TABLET to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking LUPIGEST 100MG TABLET. Drive only if you are alert, as LUPIGEST 100MG TABLET may cause drowsiness or dizziness.

Uses of LUPIGEST 100MG TABLET

LUPIGEST 100MG TABLET is used in the treatment of female infertility and female hormonal imbalance. The detailed uses of LUPIGEST 100MG TABLET are as follows:
• Hormonal Replacement Therapy: LUPIGEST 100MG TABLET is commonly used in women undergoing hormonal replacement therapy to manage symptoms associated with menopause or hormonal imbalances.
• Luteal Phase Support: LUPIGEST 100MG TABLET is prescribed to support the luteal phase during assisted reproductive technologies like in vitro fertilization (IVF), increasing the chances of pregnancy.
• Menstrual Disorders: LUPIGEST 100MG TABLET helps regulate the menstrual cycle and manage symptoms related to irregular menstruation.
• Endometrial Preparation: LUPIGEST 100MG TABLET aids in preparing the endometrium for implantation during fertility treatments, ensuring an optimal environment for a fertilized egg.
• Prevention of Miscarriage: In some cases, LUPIGEST 100MG TABLET is recommended for pregnant women with a history of recurrent miscarriages to help maintain the pregnancy and provide support during its early stages.

Directions for Use

Take LUPIGEST 100MG TABLET as prescribed by your doctor. Swallow it with a glass of water. Do not break, crush or chew it. It is best to take LUPIGEST 100MG TABLET at bedtime as it may cause dizziness or drowsiness.

Medicinal Benefits

LUPIGEST 100MG TABLET contains Progesterone that is used in combination with oestrogen for hormone replacement therapy. Also, LUPIGEST 100MG TABLET is used to treat amenorrhoea (absence of menstrual periods due to lack of progesterone) and prevent endometrial hyperplasia (unusually thick lining of the uterus). LUPIGEST 100MG TABLET replaces oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms. Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour.

How LUPIGEST 100MG TABLET Works

LUPIGEST 100MG TABLET contains progesterone, which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of LUPIGEST 100MG TABLET

  • Dizziness
  • Drowsiness
  • Headache
  • Mood changes
  • Diarrhoea
  • Vaginal discharge
  • Joint pain
  • Hot flashes (sudden feeling of warmth) 
  • Constipation

What if I have taken an overdose of LUPIGEST 100MG TABLET

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

If you are allergic to soya, LUPIGEST 100MG TABLET or any other medicines, please tell your doctor. Avoid taking LUPIGEST 100MG TABLET if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain). Avoid taking LUPIGEST 100MG TABLET if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking LUPIGEST 100MG TABLET to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking LUPIGEST 100MG TABLET. Drive only if you are alert as LUPIGEST 100MG TABLET may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking LUPIGEST 100MG TABLET. If you are about to undergo any surgery, please inform your doctor that you are taking LUPIGEST 100MG TABLET.

Drug-Drug Interactions

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ProgesteroneVenetoclax
Severe
ProgesteroneMorphine
Severe

Drug-Drug Interactions

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ProgesteroneVenetoclax
Severe
How does the drug interact with Lupigest 100mg Tablet:
Co-administration of Lupigest 100mg Tablet with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Lupigest 100mg Tablet and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
ProgesteroneMorphine
Severe
How does the drug interact with Lupigest 100mg Tablet:
Co-administration of Lupigest 100mg Tablet with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Lupigest 100mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ProgesteroneEdoxaban
Severe
How does the drug interact with Lupigest 100mg Tablet:
When Lupigest 100mg Tablet is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking Lupigest 100mg Tablet and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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PROGESTERONE-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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PROGESTERONE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grape fruit and its products may interact with Lupigest 100mg Tablet Avoid Grape fruit and its products during treatment with Lupigest 100mg Tablet

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.

  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.

  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.

  • Try to be stress-free to improve your mood swings due to hormonal fluctuations.

  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

LUPIGEST 100MG TABLET Substitute

Substitutes safety advice

  • Susten 100 mg Injection 1 ml

    by Others

    ₹149.40per tablet

  • Susten 100 Capsule 10's

    by Others

    ₹17.37per tablet

  • Naturogest 100 mg Injection 1 ml

    by Others

    ₹165.60per tablet

  • Susten 200 Injection 2 ml

    by Others

    ₹128.25per tablet

  • C-Hop-100 Injection 1 ml

    by Others

    ₹158.00per tablet

Product Substitutes

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Alcohol

Caution

Interaction of LUPIGEST 100MG TABLET with alcohol is unknown. Please consult a doctor before consuming alcohol while using LUPIGEST 100MG TABLET.

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Pregnancy

Caution

LUPIGEST 100MG TABLET supports pregnancy and helps in the maintenance of pregnancy. However, please consult a doctor if you are pregnant before taking LUPIGEST 100MG TABLET.

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Breast Feeding

Caution

LUPIGEST 100MG TABLET may be excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

LUPIGEST 100MG TABLET may cause dizziness or drowsiness. Therefore, avoid driving if you feel dizzy or drowsy after taking LUPIGEST 100MG TABLET.

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Liver

Caution

Please consult a doctor if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

LUPIGEST 100MG TABLET should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

LUPIGEST 100MG TABLET is not recommended for children.

FAQs

LUPIGEST 100MG TABLET is used in combination with oestrogen for hormone replacement therapy. Besides this, LUPIGEST 100MG TABLET also treats amenorrhoea (absence of menstrual periods) and prevents endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour.

LUPIGEST 100MG TABLET contains Progesterone that works by replacing oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms.

LUPIGEST 100MG TABLET may increase the risk of blood clots especially in patients with a history of blood clots. However, if you experience sudden chest pain, difficulty in breathing or painful swelling and redness of legs, stop taking LUPIGEST 100MG TABLET and consult a doctor immediately as these might be signs of blood clot.

If oestrogen is used alone for hormone replacement therapy, it may increase the risk of endometrial hyperplasia (excessive thickening of uterus lining) and endometrial cancer (cancer of the womb). Oestrogen in combination with LUPIGEST 100MG TABLET reduces this risk.

You are recommended to inform your doctor that you are taking LUPIGEST 100MG TABLET as you may need to stop taking LUPIGEST 100MG TABLET 4 to 6 weeks before surgery to decrease the risk of blood clot.

LUPIGEST 100MG TABLET may increase the risk of uterine cancer. However, if you experience any unusual vaginal bleeding, please consult a doctor immediately.

LUPIGEST 100MG TABLET is not a contraceptive. You are recommended to use additional contraceptive methods to prevent pregnancy while taking LUPIGEST 100MG TABLET.

LUPIGEST 100MG TABLET should be swallowed as a whole with water. Do not crush or chew it.

LUPIGEST 100MG TABLET is a hormone extracted from plants and is chemically identical to human progesterone.

Yes, LUPIGEST 100MG TABLET can be taken daily. Usually, it is taken once everyday in the evening or at bedtime.

Some people might gain weight due to other reasons while taking LUPIGEST 100MG TABLET. Consult the doctor if you notice weight gain during LUPIGEST 100MG TABLET therapy.

Yes, LUPIGEST 100MG TABLET is safe if taken in the dose and duration prescribed by the doctor.

Progesterone plays a vital role in fertility. It improves the chances of becoming and staying pregnant by preparing the uterus lining.

LUPIGEST 100MG TABLET may cause side effects like dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. If the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - LUP0029

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Author Details

Doctor imageDoctor badge

Written By

Veda Maddala

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Apr 25, 2025 | 9:20 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.352.pdf
  2. https://www.drugs.com/progesterone.html
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