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More about the Product

Composition :

CHLORPHENIRAMINE MALEATE-2MG+DEXTROMETHORPHAN HYDROBROMIDE-10MG+PHENYLEPHRINE HYDROCHLORIDE-5MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lupihist DM Plus Syrup

Lupihist DM Plus Syrup is an oral syrup used to relieve dry cough, throat irritation, sneezing, runny nose, and nasal congestion caused by the common cold, allergies, or other upper respiratory infections. It acts as a supportive treatment to manage multiple cold symptoms simultaneously by combining an antihistamine, a cough suppressant, and a decongestant. This medicine helps clear your airways and quiet your cough so your body can rest and recover.

To get the best results, take Lupihist DM Plus Syrup exactly as directed by your doctor, keeping your dosing intervals consistent throughout the day. You can take this syrup with or without food, though taking it with a small meal may help if you have a sensitive stomach. Drinking plenty of water, using a cool-mist humidifier in your room, and resting can also significantly support your recovery while using this medication.

While taking Lupihist DM Plus Syrup, you may experience mild side effects like drowsiness, dizziness, or a dry mouth. These symptoms are usually temporary and improve as your body adjusts to the syrup. However, if you experience serious side effects such as a rapid heart rate, severe dizziness, or difficulty urinating, you should contact your doctor right away.

Do not take this medicine if you have taken a monoamine oxidase inhibitor (MAOI) in the past 14 days, as this can cause a severe, life-threatening drug reaction. Before starting Lupihist DM Plus Syrup, talk to your doctor if you have a history of high blood pressure, heart disease, diabetes, glaucoma, thyroid disorders, or an enlarged prostate.

Avoid drinking alcohol while taking this medicine because it can greatly increase drowsiness and impair your coordination. If you are pregnant, breastfeeding, or planning a pregnancy, or if you are caring for an elderly patient, consult your healthcare provider before using Lupihist DM Plus Syrup to ensure it is safe.

Uses of Lupihist DM Plus Syrup

This medicine is used to relieve dry cough, nasal congestion, and allergy symptoms associated with the common cold. The detailed uses of this medicine are as follows:

  • Dry Cough: Lupihist DM Plus Syrup helps quiet a dry, non-productive cough by reducing the urge to cough.
  • Nasal Congestion: It helps reduce swelling in the nasal passages, making it easier to breathe through the nose.
  • Runny Nose and Sneezing: It helps relieve sneezing, runny nose, watery eyes, and other allergy symptoms by blocking the effects of histamine.
  • Common Cold and Allergy Relief: It helps manage multiple cold and allergy symptoms, providing comprehensive relief from upper respiratory discomfort.

Key Benefits

This medicine helps relieve dry cough, nasal congestion, and allergy symptoms for greater comfort during recovery. Its benefits include:

  • Helps reduce the urge to cough and provides relief from dry, irritating cough.
  • Helps relieve nasal congestion, making breathing easier.
  • Reduces sneezing, runny nose, and watery eyes caused by allergies or the common cold.
  • Provides relief from multiple cold and allergy symptoms in a single medicine.
  • Helps improve sleep by reducing nighttime cough and nasal blockage.
  • Supports a more comfortable recovery from cold and upper respiratory symptoms.
Side effects of Lupihist DM Plus Syrup 60 ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Try to get 7-9 hours of sleep per night.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is cool, quiet and dark to maximize your sleep quality.
  • Get plenty of sunlight in the morning.
  • Do moderate-intensity exercises most days of the week and avoid strenuous exercise close to bedtime.
  • Limit processed foods and sugary drinks.
  • Avoid caffeine late in the day and drink in moderation in the morning.
  • Take short nap (20 to 30 minutes) mid-afternoon if required.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Directions for Use

  • Lupihist DM Plus Syrup can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Avoid using regular household spoons, as they may not accurately measure the dose.

How Lupihist DM Plus Syrup Works

Lupihist DM Plus Syrup contains Chlorpheniramine Maleate, Dextromethorphan Hydrobromide, and Phenylephrine Hydrochloride. Chlorpheniramine Maleate: It is an antihistamine that blocks the action of histamine, helping relieve sneezing, runny nose, watery eyes, and other allergy symptoms. Dextromethorphan Hydrobromide: It is a cough suppressant that acts on the cough center in the brain to reduce the urge to cough, helping relieve dry, irritating cough. Phenylephrine Hydrochloride: It is a nasal decongestant that narrows swollen blood vessels in the nasal passages, reducing congestion and making it easier to breathe.
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Alcohol

Caution

Avoid consumption of alcohol with Lupihist DM Plus Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Lupihist DM Plus Syrup.

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Pregnancy

Caution

The safety of Lupihist DM Plus Syrup in pregnant women is unknown. Consult your doctor if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Lupihist DM Plus Syrup is excreted in human milk. Consult your doctor if you have any concerns; your doctor will decide if Lupihist DM Plus Syrup can be taken by breastfeeding mothers or not.

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Driving

Caution

Lupihist DM Plus Syrup may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Lupihist DM Plus Syrup.

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Liver

Caution

Take Lupihist DM Plus Syrup with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Lupihist DM Plus Syrup with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Lupihist DM Plus Syrup is not recommended for children below 12 years of age. However, please consult a doctor if you have any concerns.

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Heart

Caution

Lupihist DM Plus Syrup should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Lupihist DM Plus Syrup.

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Geriatrics

Caution

Lupihist DM Plus Syrup should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Lupihist DM Plus Syrup.

What if I have taken an overdose of Lupihist DM Plus Syrup

If you suspect an overdose or have taken too much syrup, seek emergency medical attention or contact a poison control center immediately. Symptoms of an overdose may include extreme drowsiness, severe dizziness, rapid heart rate, hallucinations, or shallow breathing.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink warm liquids such as herbal tea, broths, or warm water with lemon. This helps keep your throat moist, thin mucus, and soothe irritation.
  • Use a cool-mist humidifier: Keep a humidifier in your bedroom to add moisture to the air, helping soothe irritated airways and reduce nighttime coughing.
  • Elevate your head: Use an extra pillow while resting to help drain your nasal passages and reduce post-nasal drip that can trigger coughing.
  • Avoid throat irritants: Stay away from tobacco smoke, dust, and strong chemical fumes, as they can worsen your cough and irritate your airways.
health query

Have a query?

How Soon It Starts Working

  • The time required for Lupihist DM Plus Syrup to start to work: Lupihist DM Plus Syrup ideally shows its action within 15 to 30 minutes after administration.
  • The time for which the effects of Lupihist DM Plus Syrup last: The effect of Lupihist DM Plus Syrup lasts for 4 to 6 hours.

What if you forget to take Lupihist DM Plus Syrup

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Lupihist DM Plus Syrup syrup at room temperature, ideally between 15°C and 30°C (59°F to 86°F). Keep the bottle tightly closed when not in use.

Drug Warnings

  • Check the liquid: Inspect the syrup before each use to ensure it is clear and free of floating particles. Do not use it if the color has changed significantly.
  • Avoid driving or operating machinery: This medicine may cause drowsiness. Avoid driving, cycling, or operating heavy machinery until you know how it affects you.
  • Check other cold medications: Read the labels of other cold, cough, or allergy medicines carefully to avoid taking the same or similar active ingredients twice.
  • Avoid alcohol: Do not drink alcohol while taking this medicine, as it can increase drowsiness and the risk of side effects.
  • Monitor blood pressure: If you have high blood pressure, check it regularly while using this medicine, as the decongestant may increase blood pressure.

Drug-Drug Interactions

verifiedApollotooltip
  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine with or within 14 days of stopping an MAOI (such as phenelzine or selegiline), as it can cause a dangerous rise in blood pressure.
  • Other Central Nervous System (CNS) Depressants: Taking this medicine with sleeping pills, anxiety medicines, muscle relaxants, or opioid pain relievers may increase drowsiness and slow breathing.
  • Antidepressants (SSRIs/SNRIs): Taking this medicine with certain antidepressants (such as fluoxetine or paroxetine) may increase the risk of serotonin syndrome.
Chlorpheniramine + Phenylephrine + DextromethorphanRasagiline
Critical
Chlorpheniramine + Phenylephrine + DextromethorphanPropofol
Critical

Drug-Drug Interactions

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Chlorpheniramine + Phenylephrine + DextromethorphanRasagiline
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Taking Lupihist DM Plus Syrup 60 ml with Dextromethorphan can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Lupihist DM Plus Syrup 60 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanPropofol
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Taking Lupihist DM Plus Syrup 60 ml with Propofol may lead to increased levels of phenylephrine leading to side effects.

How to manage the interaction:
Taking Lupihist DM Plus Syrup 60 ml with Propofol is not recommended, as it can lead to an interaction, but it can be taken if prescribed by a doctor. Do not discontinue the medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanPotassium citrate
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Taking Lupihist DM Plus Syrup 60 ml with Potassium chloride may make potassium more irritating to your upper intestine and stomach.

How to manage the interaction:
Taking Lupihist DM Plus Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + Phenylephrine + DextromethorphanSelegiline
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Lupihist DM Plus Syrup 60 ml with selegiline can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body) and high blood pressure.

How to manage the interaction:
Co-administration of Lupihist DM Plus Syrup 60 ml with Selegiline can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these symptoms - confusion, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, diarrhea, severe headache, chest pain, sudden numbness or weakness (especially on one side of the body), speech difficulties, lightheadedness, and/or fainting - make sure to contact a doctor right away. Do not stop using any medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanPhenelzine
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Lupihist DM Plus Syrup 60 ml with Phenelzine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body) and high blood pressure.

How to manage the interaction:
Co-administration of Lupihist DM Plus Syrup 60 ml with Phenelzine can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these symptoms - confusion, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, diarrhea, severe headache, chest pain, sudden numbness or weakness (especially on one side of the body), speech difficulties, lightheadedness, and/or fainting - make sure to contact a doctor right away. Do not stop using any medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanProcarbazine
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Lupihist DM Plus Syrup 60 ml with Procarbazine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body) and high blood pressure.

How to manage the interaction:
Co-administration of Lupihist DM Plus Syrup 60 ml with Procarbazine can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these symptoms - confusion, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, diarrhea, severe headache, chest pain, sudden numbness or weakness (especially on one side of the body), speech difficulties, lightheadedness, and/or fainting - make sure to contact a doctor right away. Do not stop using any medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanFurazolidone
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Lupihist DM Plus Syrup 60 ml with Furazolidone can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body) and high blood pressure.

How to manage the interaction:
Co-administration of Lupihist DM Plus Syrup 60 ml with Furazolidone can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these symptoms - confusion, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, diarrhea, severe headache, chest pain, sudden numbness or weakness (especially on one side of the body), speech difficulties, lightheadedness, and/or fainting - make sure to contact a doctor right away. Do not stop using any medications without consulting a doctor.
Chlorpheniramine + Phenylephrine + DextromethorphanMethylene blue
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Lupihist DM Plus Syrup 60 ml with Methylene blue can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although taking Lupihist DM Plus Syrup 60 ml together with Methylene blue is not recommended as it can result in an interaction, it can be taken if prescribed by a doctor. However, if you develop confusion, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + Phenylephrine + DextromethorphanTranylcypromine
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Co-administration of Lupihist DM Plus Syrup 60 ml with Tranylcypromine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although taking Lupihist DM Plus Syrup 60 ml together with Tranylcypromine is not recommended as it can result in an interaction, it can be taken if prescribed by a doctor. However, if you develop confusion, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Chlorpheniramine + Phenylephrine + DextromethorphanPotassium chloride
Critical
How does the drug interact with Lupihist DM Plus Syrup 60 ml:
Taking Lupihist DM Plus Syrup 60 ml with Potassium chloride may make potassium more irritating to your upper intestine and stomach.

How to manage the interaction:
Taking Lupihist DM Plus Syrup 60 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid drinking alcohol while taking this medicine, as it can significantly increase drowsiness and other side effects. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[COUGH AND COLD PREPARATIONS ]

FAQs

Lupihist DM Plus Syrup is used to treat dry cough. It helps relieve cough, cold, and allergic symptoms.
Lupihist DM Plus Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough.
Consult your doctor before taking Lupihist DM Plus Syrup if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Your doctor may advise you to stop taking Lupihist DM Plus Syrup 72 hours prior to the surgery.
It is not recommended to take Lupihist DM Plus Syrup along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or drug interaction. Also, Lupihist DM Plus Syrup should be taken at least 14 days after the last dose of anti-depressants.
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the scheduled dose. Do not take extra medicine to make up for the missed dose.
Lupihist DM Plus Syrup may rarely worsen the symptoms of glaucoma. Therefore, Lupihist DM Plus Syrup should be used with caution and only when prescribed by a doctor in patients with glaucoma.
No, Lupihist DM Plus Syrup does not contain steroids. It is a combination of three active ingredients phenylephrine, chlorpheniramine maleate, and dextromethorphan hydrobromide.
Yes, Lupihist DM Plus Syrup can make you feel drowsy as a side effect. It contains dextromethorphan and chlorpheniramine, both of which can cause drowsiness. It's important to be cautious when performing activities that require alertness, such as driving or operating machinery, until you know how the medication affects you.
No, taking Lupihist DM Plus Syrup in more than the recommended dose will not make it more effective. Instead, it can increase the risk of side effects. It's important to follow the dosage instructions provided by your doctor to ensure safe and effective use of the medication.
It is generally not recommended to breastfeed while taking Lupihist DM Plus Syrup. Lupihist DM Plus Syrup contains chlorpheniramine, an antihistamine, which can pass into the breast milk and may harm the baby. Therefore, inform your doctor that you are breastfeeding if you are advised to take this medicine.
Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack. Follow your doctor’s instructions regarding dosage and duration.
Yes Lupihist DM Plus Syrup causes some side effects such as dry mouth, throat or nose, drowsiness, dizziness, blurred vision, headache, constipation, restlessness or excitation, and loss of appetite. If any of these side effects persist or worsen, please consult your doctor.
Yes, inform your doctor if your child has conditions like glaucoma, urinary retention, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, and chronic bronchitis or emphysema (a lung condition causing shortness of breath).
No, Lupihist DM Plus Syrup interacts with other medications, including, MOIs (monoamine oxidase inhibitors), antidepressants, sedatives or tranquillizers, and alcohol. Therefore, you should inform your doctor about all the medicines, supplements, and herbal products they are currently taking before starting Lupihist DM Plus Syrup.
Store Lupihist DM Plus Syrup at room temperature in a cool and dry place away from sunlight. Do not freeze. Keep it out of reach of children.
If you have high blood pressure, use this medicine with caution. The decongestant ingredient may raise your blood pressure. Talk to your doctor before using this medicine.
It is generally not recommended because many allergy medicines contain similar antihistamines, increasing the risk of excessive drowsiness or accidental overdose. Talk to your doctor or pharmacist before combining medicines.
Use this medicine during pregnancy or breastfeeding only if recommended by your doctor after assessing the benefits and risks. Consult your doctor before taking this medicine.
Stop taking the medicine and consult your doctor if your cough lasts longer than 7 days, returns after improving, or is accompanied by a high fever, rash, or persistent headache.
Yes. You can take this medicine with or without food. If it causes stomach upset, taking it with food or milk may help. Talk to your doctor if stomach discomfort persists.

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Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Other Info - LUP0372
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