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  3. LURAKEM 80MG TABLET 10'S

LURAKEM 80MG TABLET 10'S, Pack of 10 TabletS
LURAKEM 80MG TABLET 10'S, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
LURAKEM 80MG TABLET is used to treat schizophrenia and bipolar disorder. It contains Lurasidone which works by blocking neurotransmitters and helps regulate mood, thoughts and behaviour. In some cases, this medicine may cause side effects such as nausea, vomiting, sleepiness, weight gain, indigestion, dry mouth, and restlessness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Synonym :

LURASIDONE HYDROCHLORIDE

Composition :

LURASIDONE

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About LURAKEM 80MG TABLET

LURAKEM 80MG TABLET used in the treatment of schizophrenia (affects a person's ability to feel, think and behave clearly) and bipolar depression (mood swings). Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused. Bipolar disorder is characterized by manic episodes in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behaviour changes. 

LURAKEM 80MG TABLET contains ‘lurasidone’, which is an antipsychotic drug. It acts by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia and bipolar disorder. LURAKEM 80MG TABLET also blocks other neurotransmitters in the brain, such as serotonin. By blocking both, LURAKEM 80MG TABLET helps to control the brain's activity and decrease the symptoms of schizophrenia and bipolar disease.

Take LURAKEM 80MG TABLET as prescribed by your doctor. You are advised to take LURAKEM 80MG TABLET for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience nausea, vomiting, sleepiness, weight gain, indigestion, dryness in the mouth, akathisia (inability to stay still), stomach discomfort, anxiety, upper abdominal pain, restlessness, agitation (nervous excitement), insomnia (difficulty in sleeping) and increased saliva production. Most of these side effects of LURAKEM 80MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

LURAKEM 80MG TABLET should not be taken in conditions like if you are allergic to lurasidone or any other ingredients present in it. Before taking LURAKEM 80MG TABLET , inform your doctor if you have problems associated with the liver, kidney or heart and low blood pressure. It is not recommended for use in children under 13 years of age. Before taking LURAKEM 80MG TABLET inform your doctor if you are older than 65 years of age as it causes more side effects. Tell your doctor if you are pregnant or breastfeeding. LURAKEM 80MG TABLET causes drowsiness and dizziness. Do not drive unless you are alert.

Uses of LURAKEM 80MG TABLET

Treatment of Schizophrenia, Bipolar disorder

Directions for Use

Take LURAKEM 80MG TABLET with or without food. LURAKEM 80MG TABLET should be swallowed as a whole with a glass of water; do not chew or crush the tablet. You are advised to take LURAKEM 80MG TABLET for as long as your doctor has prescribed it for you, depending on your medical condition.

Medicinal Benefits

LURAKEM 80MG TABLET is used to treat certain mood /mental diseases like schizophrenia and depression related to bipolar disorder. LURAKEM 80MG TABLET  helps you to feel less nervous, think more clearly and take part in daily life. It may also help to reduce hallucinations (seeing/hearing things that are not there). It alters brain function and improves mood, thinking ability, and social behaviour. It reduces the development of symptoms in patients with schizophrenia, bipolar disorder or other mood disorders. 

How LURAKEM 80MG TABLET Works

LURAKEM 80MG TABLET contains lurasidone, which is an antipsychotic drug. It acts by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia and bipolar disorder. LURAKEM 80MG TABLET also blocks other neurotransmitters in the brain, such as serotonin. By blocking both, LURAKEM 80MG TABLET helps to control the brain's activity and decrease the symptoms of schizophrenia and bipolar disease.

Storage

Store in a cool and dry place away from sunlight
Side effects of Lurakem 80mg Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.

What if I have taken an overdose of LURAKEM 80MG TABLET

Take LURAKEM 80MG TABLET only as prescribed by the doctor. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

It is advisable to you not take LURAKEM 80MG TABLET if you are allergic to lurasidone or any ingredients present in it. Before taking LURAKEM 80MG TABLET , inform your doctor if you have low blood pressure, stroke, liver problems, seizures, diabetes, dementia (memory loss), alcohol or drug abuse, sleep apnea (a sleep disorder) and urinary retention. Inform your doctor if you have epilepsy/fits, an increase in your weight, history of blood clots before taking LURAKEM 80MG TABLET . Tell your doctor immediately if you develop suicidal thoughts, or your depression worsens after taking LURAKEM 80MG TABLET . There is a greater chance of death in senior adults who take LURAKEM 80MG TABLET for mental problems caused by dementia (thinking and suicidal symptoms). Most of the deaths were related to infection or heart disease. Avoid drinking alcohol while taking LURAKEM 80MG TABLET as it may worsen the side effects. Tell your doctor if you are pregnant or breastfeeding. LURAKEM 80MG TABLET causes drowsiness and dizziness. Do not drive unless you are alert.

Drug-Drug Interactions

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LurasidonePosaconazole
Critical
LurasidoneImatinib
Critical

Drug-Drug Interactions

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LurasidonePosaconazole
Critical
How does the drug interact with Lurakem 80mg Tablet:
Taking Lurakem 80mg Tablet together with posaconazole may result in significantly higher Lurakem 80mg Tablet blood levels.

How to manage the interaction:
Although there is an interaction between Lurakem 80mg Tablet and posaconazole, they can be used if prescribed by a doctor. However, consult a doctor if you have any abnormal muscle activity, dizziness, lightheadedness, headache, flushing, or fainting. Do not discontinue any medications without consulting a doctor.
LurasidoneImatinib
Critical
How does the drug interact with Lurakem 80mg Tablet:
Using Lurakem 80mg Tablet together with Imatinib may result in significantly higher Lurakem 80mg Tablet blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
Taking Lurakem 80mg Tablet with Imatinib is not recommended as it leads to an interaction, it can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
LurasidoneMetoclopramide
Critical
How does the drug interact with Lurakem 80mg Tablet:
The combination of Lurakem 80mg Tablet and Metoclopramide may result in significantly increased Lurakem 80mg Tablet blood levels. This may raise the possibility of undesirable consequences such as Parkinson's disease. (It is a neurological condition that causes uncontrollable movements)and Tardive dyskinesia (uncontrollable movements, particularly of the lower face).

How to manage the interaction:
Lurakem 80mg Tablet and Metoclopramide is not recommended, as they may interact, but can be used if a doctor prescribes them. Consult a doctor if you have muscle spasms, or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning, tongue thrusting, teeth clenching, jaw twitching, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without visiting a doctor.
LurasidoneFosphenytoin
Critical
How does the drug interact with Lurakem 80mg Tablet:
Lurakem 80mg Tablet co-administration with Fosphenytoin may result in significantly lower blood levels of Lurakem 80mg Tablet, making the medication less effective or ineffective in treating your illness.

How to manage the interaction:
Although there is an interaction between Lurakem 80mg Tablet and Fosphenytoin, you can take it if your doctor has prescribed it. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LurasidoneVoriconazole
Critical
How does the drug interact with Lurakem 80mg Tablet:
Using Lurakem 80mg Tablet together with Voriconazole may result in significantly higher Lurakem 80mg Tablet blood levels.

How to manage the interaction:
While Lurakem 80mg Tablet and Voriconazole may interact, it is not recommended that they be used unless prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, dizziness, headache, or heart palpitations. Do not discontinue any medications without consulting a doctor.
LurasidoneRifapentine
Critical
How does the drug interact with Lurakem 80mg Tablet:
Lurakem 80mg Tablet co-administration with Rifapentine may result in significantly lower blood levels of Lurakem 80mg Tablet, making the medication less effective or ineffective in treating your illness.

How to manage the interaction:
There is an interaction between Lurakem 80mg Tablet and Rifapentine, so it is not recommended that you take it unless your doctor has prescribed it. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LurasidonePhenobarbital
Critical
How does the drug interact with Lurakem 80mg Tablet:
Co-administration of Lurakem 80mg Tablet with Phenobarbitalmay result in significantly lower blood levels of Lurakem 80mg Tablet, making the medication less effective or ineffective in treating the illness.

How to manage the interaction:
There is an interaction between Lurakem 80mg Tablet and phenobarbital,so it is not recommended. You can take it if a doctor has prescribed it. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LurasidoneTelaprevir
Critical
How does the drug interact with Lurakem 80mg Tablet:
Using Lurakem 80mg Tablet together with Telaprevir may result in significantly higher Lurakem 80mg Tablet blood levels. This may increase the possibility of side effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurakem 80mg Tablet and Telaprevir may interact, it is not recommended, but they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
LurasidoneMifepristone
Critical
How does the drug interact with Lurakem 80mg Tablet:
Coadministration of Lurakem 80mg Tablet with Mifepristone can increase the levels of Lurakem 80mg Tablet which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Lurakem 80mg Tablet with Mifepristone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any abnormal muscle movements, seizures(fits), high blood sugar, dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LurasidoneDarunavir
Critical
How does the drug interact with Lurakem 80mg Tablet:
Using Lurakem 80mg Tablet together with Darunavir may result in significantly higher Lurakem 80mg Tablet blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurakem 80mg Tablet and Darunavir may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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LURASIDONEGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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LURASIDONEGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Taking grapefruit juice with Lurakem 80mg Tablet treatment can increase the levels of Lurakem 80mg Tablet which can increase the risk or severity of side effects. Taking grapefruit juice with Lurakem 80mg Tablet should be avoided as it can result in an interaction. Contact a doctor immediately if you experience symptoms like abnormal muscle movements, seizures, dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations. Do not stop using any medications without talking to a doctor.

Diet & Lifestyle Advise

  • Do not take grapefruit or grapefruit juice while using LURAKEM 80MG TABLET as it may alter the effects of the medicine.
  • Avoid intense exercise as it is harder for the body to cool down when it gets very hot. So, drink plenty of fluids and avoid going out in hot weather.
  • Do not take alcohol as it increases drowsiness and also worsens the disease condition. 
  • Eat healthily and keep a check on your weight regularly.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

LURAKEM 80MG TABLET Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consuming alcohol while on treatment with LURAKEM 80MG TABLET as it may increase the risk of side effects.

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Pregnancy

Caution

LURAKEM 80MG TABLET is not recommended for use in pregnancy. Hence, if you are pregnant, inform your doctor before taking LURAKEM 80MG TABLET . Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if LURAKEM 80MG TABLET passes into the breastmilk. If you are breastfeeding, consult your doctor before taking LURAKEM 80MG TABLET , your doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

LURAKEM 80MG TABLET may cause dizziness. So, it is not recommended to drive or operate heavy machinery after taking LURAKEM 80MG TABLET .

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Liver

Caution

LURAKEM 80MG TABLET should be used with caution in patients with liver disease. If you have liver disease, inform your doctor before taking LURAKEM 80MG TABLET . Your doctor may adjust the dose based on your condition.

bannner image

Kidney

Caution

LURAKEM 80MG TABLET should be used with caution in patients with kidney disease. If you have kidney disease, inform your doctor before taking LURAKEM 80MG TABLET . Your doctor may adjust the dose based on your condition.

bannner image

Children

Unsafe

LURAKEM 80MG TABLET is not recommended for use in children under 13 years.

Have a query?

FAQs

LURAKEM 80MG TABLET is used in the treatment of schizophrenia (affects a person's ability to feel, think and behave clearly) and bipolar depression (mood swings). It helps you to feel less nervous, think more clearly and take part in daily life.

LURAKEM 80MG TABLET may cause an increase in blood glucose (sugar) levels. So, regular monitoring of blood sugar levels is advised while taking LURAKEM 80MG TABLET . Diabetes patients should consult a doctor before taking LURAKEM 80MG TABLET .

Weight gain is a common side effect of LURAKEM 80MG TABLET , although not everyone is affected. If you experience weight gain on taking LURAKEM 80MG TABLET , inform your doctor. Eating a healthy diet and frequent exercise can help you maintain your weight.

Alcohol should be avoided while taking LURAKEM 80MG TABLET since taking both together may lead to severe side effects. You should not drink grapefruit juice while on LURAKEM 80MG TABLET as it affects the way it works.

LURAKEM 80MG TABLET may raise the risk of death in older persons who suffer from memory loss, perplexity, or have lost touch with reality. It is critical to understand that LURAKEM 80MG TABLET may cause suicidal behaviour or thoughts in certain children, adolescents, and young adults during the first few months of treatment and when the dose is adjusted.

Dry mouth could be a side-effect of LURAKEM 80MG TABLET . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

LURAKEM 80MG TABLET is an antipsychotic drug that works by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia (a serious mental illness affecting thoughts, feelings, and behaviours) and bipolar disorder (a mental illness that causes mood swings, energy fluctuations, and concentration issues). It also blocks other neurotransmitters in the brain, such as serotonin. By blocking both dopamine and serotonin, LURAKEM 80MG TABLET helps to control brain activity and decreasesthe symptoms of schizophrenia and bipolar disorder.

The common side effects of LURAKEM 80MG TABLET include nausea, vomiting, weight gain, indigestion, sleepiness, dryness in the mouth, increased saliva production, akathisia (inability to stay still), anxiety, upper abdominal pain, restlessness, agitation (nervous excitement), and insomnia (difficulty in sleeping). Most of these side effects of LURAKEM 80MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

No, LURAKEM 80MG TABLET should not be used during pregnancy unless prescribed by the doctor. Taking LURAKEM 80MG TABLET in the later months of pregnancy may lead to extrapyramidal (uncontrolled body movements or muscle stiffness in the baby) or withdrawal symptoms after birth such as muscle stiffness, weakness, shakiness, sleepiness, breathing problems, agitation, and difficulty feeding. If you are pregnant or planning for pregnancy, please consult your doctor before taking LURAKEM 80MG TABLET . The doctor will prescribe LURAKEM 80MG TABLET only if the benefits outweigh the risks and will monitor the baby closely after birth.

Close monitoring for the emergence or worsening of suicidal behaviour and thoughts is recommended in patients taking LURAKEM 80MG TABLET . LURAKEM 80MG TABLET may increase blood sugar levels in diabetic patients, especially in those with schizophrenia. So, you should immediately inform your doctor if you experience symptoms such as increased thirst, frequent urination, fatigue, or increased appetite. It may also lead to weight gain, increase prolactin, cholesterol, and triglyceride levels, and decrease white blood cell count. Hence, regular monitoring of blood sugar levels, blood cell counts, hormone levels (prolactin), and cholesterol levels is advised while taking LURAKEM 80MG TABLET . 

LURAKEM 80MG TABLET should be taken with food for better absorption of the medicine. It should be swallowed whole with a glass of water; do not chew or crush the tablet.

LURAKEM 80MG TABLET may take several weeks or longer before you experience any improvement in your symptoms. Continue to take LURAKEM 80MG TABLET even if you feel well, and do not stop taking it without talking to your doctor.

Yes, LURAKEM 80MG TABLET can cause dizziness, fainting, and lightheadedness when you stand up too quickly after lying down. This is more likely to happen when you first start taking LURAKEM 80MG TABLET or if your dose changes. To help prevent this problem, rise slowly from the bed and allow your feet to rest on the floor for a few minutes before standing up.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - LUR0017

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.drugs.com/cdi/lurasidone.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/200603s015lbl.pdf
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