MACOX PLUS 150MG TABLET
MRP ₹78.5
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About MACOX PLUS 150MG TABLET
MACOX PLUS 150MG TABLET is used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.
MACOX PLUS 150MG TABLET is a combination of two anti-tuberculosis drugs Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, MACOX PLUS 150MG TABLET kills Mycobacterium tuberculosis, which causes TB (tuberculosis).
In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhoea, gas, and numbness or tingling sensation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Consult your doctor before taking MACOX PLUS 150MG TABLET if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking MACOX PLUS 150MG TABLET as it passes into breast milk. MACOX PLUS 150MG TABLET may cause dizziness, and vision problems, so drive only if you are alert. Avoid alcohol consumption while taking MACOX PLUS 150MG TABLET as it could lead to increased drowsiness, dizziness and liver damage.
Uses of MACOX PLUS 150MG TABLET
MACOX PLUS 150MG TABLET is used in the treatment of tuberculosis (TB). The detailed uses of MACOX PLUS 150MG TABLET are as follows:
- Treats active tuberculosis: MACOX PLUS 150MG TABLET works by killing the bacteria that cause TB, helping to clear the infection from the lungs and other affected organs.
- Prevents spread and recurrence: MACOX PLUS 150MG TABLET is also used to prevent TB from coming back or spreading to others, especially in people at high risk.
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Directions for Use
- MACOX PLUS 150MG TABLET should be taken on an empty stomach, at least 30 minutes before or 2 hours after a meal.
- It is usually taken once daily or as prescribed by your doctor.
- Swallow MACOX PLUS 150MG TABLET as a whole with a glass of water.
- Do not crush or chew this medication.
Key Benefits
MACOX PLUS 150MG TABLET is a combination of two anti-tuberculosis drugs, Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, MACOX PLUS 150MG TABLET kills Mycobacterium tuberculosis, which causes TB (tuberculosis).
How MACOX PLUS 150MG TABLET Works
Storage
What if I have taken an overdose of MACOX PLUS 150MG TABLET
Drug Warnings
Do not take MACOX PLUS 150MG TABLET if you are allergic to any of its contents; if you have jaundice, or if you are taking HIV medicines (saquinavir or ritonavir). Before starting MACOX PLUS 150MG TABLET, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult your doctor before taking MACOX PLUS 150MG TABLET if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking MACOX PLUS 150MG TABLET as it passes into breast milk. MACOX PLUS 150MG TABLET may cause dizziness, and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking MACOX PLUS 150MG TABLET as it could lead to increased drowsiness, dizziness and liver damage.
Drug-Drug Interactions
Drug-Drug Interactions
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Taking saquinavir with Macox Plus 150mg Tablet can increase the risk or severity of side effects.
How to manage the interaction:
Although there is an interaction between pyrazinamide and Macox Plus 150mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
When Indinavir is taken with Macox Plus 150mg Tablet, it can reduce the blood levels and effects of Indinavir.
How to manage the interaction:
Although there is an interaction between indinavir and Macox Plus 150mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Voriconazole with Macox Plus 150mg Tablet can increase blood level of Voriconazole.
How to manage the interaction:
Although there is an interaction between Voriconazole with Macox Plus 150mg Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
When ranolazine is taken with Macox Plus 150mg Tablet, it can reduce the blood levels and effects of ranolazine.
How to manage the interaction:
Although there is an interaction between ranolazine and Macox Plus 150mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking pirfenidone with Macox Plus 150mg Tablet can reduce the levels and effects of pirfenidone
How to manage the interaction:
Although there is an interaction between pirfenidone and Macox Plus 150mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking darunavir with Macox Plus 150mg Tablet can decrease the blood levels of darunavir, which may make the medication less effective.
How to manage the interaction:
Although there is an interaction between darunavir and Macox Plus 150mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
When Macox Plus 150mg Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.
How to manage the interaction:
Taking Regorafenib with Macox Plus 150mg Tablet is not recommended, it taken can be taken if prescribed by the doctor.
When Lovastatin is taken with Macox Plus 150mg Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).
How to manage the interaction:
Taking Macox Plus 150mg Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
When Lomitapide is taken with Macox Plus 150mg Tablet, Macox Plus 150mg Tablet may increase the blood levels of lomitapide which leads to side effects.
How to manage the interaction:
Taking Macox Plus 150mg Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
Coadministration of Desogestrel with Macox Plus 150mg Tablet may reduce the blood levels and effects of Desogestrel.
How to manage the interaction:
Although there is an interaction between desogestrel and Macox Plus 150mg Tablet, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
Foods rich in vitamin C such as kiwi, broccoli, and bell pepper helps in improving the immune system.
Avoid processed and fried foods.
Warm ginger tea or warm soup can help in providing relief from cough.
Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
Quit smoking and avoid alcohol consumption.
Habit Forming
Therapeutic Class
Alcohol
Safe if prescribed
Avoid alcohol consumption while taking MACOX PLUS 150MG TABLET as it could lead to increased drowsiness, dizziness and liver damage.
Pregnancy
Consult your doctor
Please consult your doctor if you are pregnant, your doctor will prescribe MACOX PLUS 150MG TABLET only if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
MACOX PLUS 150MG TABLET passes into breast milk. Do not breastfeed while taking MACOX PLUS 150MG TABLET.
Driving
Safe if prescribed
MACOX PLUS 150MG TABLET may cause dizziness, drowsiness, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.
Liver
Consult your doctor
Dose adjustment may be needed. Please consult your doctor before taking MACOX PLUS 150MG TABLET if you have liver impairment/liver disease.
Kidney
Consult your doctor
Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking MACOX PLUS 150MG TABLET.
Children
Safe if prescribed
Please consult your doctor. Your doctor may suggest suitable dose and dosage form based on your child's age, body weight and medical condition. Kid tablets could be used in children if prescribed by the doctor.
Heart
MACOX PLUS 150MG TABLET can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.
Geriatrics
Consult your doctor
MACOX PLUS 150MG TABLET is not recommended for use in elderly patients as it can lead to side effects.
FAQs
MACOX PLUS 150MG TABLET belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis.
MACOX PLUS 150MG TABLET is a combination of two anti-tuberculosis drugs, namely: Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, MACOX PLUS 150MG TABLET kills Mycobacterium tuberculosis which causes TB (tuberculosis).
Do not stop taking MACOX PLUS 150MG TABLET despite symptomatic relief. To treat your condition effectually, continue taking MACOX PLUS 150MG TABLET for as long as it has been prescribed for you.
Do not take MACOX PLUS 150MG TABLET along with antacids as it might decrease the effectiveness of MACOX PLUS 150MG TABLET. Maintain a minimum gap of 1hour between both.
Consult your doctor before taking MACOX PLUS 150MG TABLET with other medicines. Medicines used to treat TB such as PAS (P-amino salicylic acid) and cycloserine should be taken 8hours apart from MACOX PLUS 150MG TABLET.
MACOX PLUS 150MG TABLET contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer. Avoid these foods while taking MACOX PLUS 150MG TABLET.
MACOX PLUS 150MG TABLET might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking MACOX PLUS 150MG TABLET. Consult your doctor if you have any concerns regarding this; your doctor may suggest an alternate method of contraception.
MACOX PLUS 150MG TABLET may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time even after you stop taking MACOX PLUS 150MG TABLET. Do not worry as it is a common side-effect of MACOX PLUS 150MG TABLET.
Yes, MACOX PLUS 150MG TABLET might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking MACOX PLUS 150MG TABLET.
MACOX PLUS 150MG TABLET may affect test results of some blood tests such as tests for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking MACOX PLUS 150MG TABLET.
Yes, MACOX PLUS 150MG TABLET may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking MACOX PLUS 150MG TABLET to check how your liver is functioning.
Yes, MACOX PLUS 150MG TABLET can cause temporary discoloration of urine and sweat. This is a common and harmless side effect.
MACOX PLUS 150MG TABLET is a combination of two anti-tuberculosis drugs, Rifampicin and Isoniazid. It is used in the treatment of Tuberculosis.
Before using MACOX PLUS 150MG TABLET, you should learn about its use, side effects, and limitations.
If you forget a dose of MACOX PLUS 150MG TABLET, take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.
The best time to take MACOX PLUS 150MG TABLET is 30 minutes before food or 2 hours after food. This helps your body absorb the medication more effectively.
Store MACOX PLUS 150MG TABLET in a cool, dry place out of sunlight and children's reach. Check the expiration date regularly. To dispose of it, place it in a plastic bag and throw it away in household trash. Never flush it down the toilet or sink.
You should avoid alcohol while taking MACOX PLUS 150MG TABLET strictly to ensure safety and efficacy, as it can increase the risk of liver damage when combined with medications like Isoniazid and Rifampicin.
Common side effects of MACOX PLUS 150MG TABLET may include drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.
MACOX PLUS 150MG TABLET is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
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