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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About MACPRIL H 2.5MG TABLET

MACPRIL H 2.5MG TABLET is used to treat blood pressure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

MACPRIL H 2.5MG TABLET contains Ramipril and Hydrochlorothiazide. Ramipril relaxes the blood vessels and improves blood flow. Hydrochlorothiazide works by increasing the amount of urine passed out from the kidneys.

Sometimes, you may experience headaches, tiredness, a slow heart rate, and nausea. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take MACPRIL H 2.5MG TABLET if you are allergic to any of its components. MACPRIL H 2.5MG TABLET is not recommended in pregnancy and lactation. Keep your doctor informed about your health condition and medications to prevent any interactions.

Uses of MACPRIL H 2.5MG TABLET

MACPRIL H 2.5MG TABLET is used in the treatment of Hypertension (high blood pressure). The detailed uses of MACPRIL H 2.5MG TABLET are as follows:

  • Hypertension (High Blood Pressure): MACPRIL H 2.5MG TABLET controls blood pressure when single-drug therapy isn’t enough.
  • Prevention of Cardiovascular Events: MACPRIL H 2.5MG TABLET lowers risk of heart attack, stroke, and heart failure.

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Directions for Use

  • Take MACPRIL H 2.5MG TABLET with or without food as advised by your doctor.
  • It is advised to take MACPRIL H 2.5MG TABLET once daily in the morning; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow MACPRIL H 2.5MG TABLET as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • MACPRIL H 2.5MG TABLET contains Ramipril and Hydrochlorothiazide, which lower and maintain healthy blood pressure levels.
  • By controlling hypertension, it helps prevent serious cardiovascular events such as heart attack, stroke, and heart failure.
  • Ramipril, an ACE inhibitor, blocks the production of angiotensin II, which relaxes and widens blood vessels to improve blood flow.
  • Hydrochlorothiazide acts as a diuretic, increasing urine output to remove extra salt and water from the body, thereby reducing fluid retention (oedema).
  • By lowering both blood pressure and fluid buildup, MACPRIL H 2.5MG TABLET helps the heart pump blood more efficiently.
  • It helps relieve swelling associated with heart, liver, kidney, or lung disorders by reducing excess fluid accumulation.
  • The combined action of both ingredients maintains optimal circulation and prevents strain on the heart and arteries.

How MACPRIL H 2.5MG TABLET Works

MACPRIL H 2.5MG TABLET contains two medicines: Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretic or water pill). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers high blood pressure by blocking a naturally occurring substance known as angiotensin II (which tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Macpril H 2.5mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
  • Add legumes, whole grains, fruits, vegetables, nuts and seeds in your diet.
  • Limit refined carbohydrates, sugary drinks and processed foods.
  • Eat healthy fats such as olive oil, avocado and nuts in moderate amounts.
  • Choose poultry, fish and lean meat sources.
  • To control calorie intake, pay attention to serving sizes.
  • Do regular exercise for 150 minutes per week, like cycling, walking or swimming.
  • Aim for weight loss if you are overweight as even losing small amount of weight can have a big impact on glucose intolerance.
  • Quit smoking and limit alcohol consumption.
  • Get sufficient sleep to support hormone regulation and overall health.

What if I have taken an overdose of MACPRIL H 2.5MG TABLET

An overdose of MACPRIL H 2.5MG TABLET may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take MACPRIL H 2.5MG TABLET if you are allergic to any of its components, or if you have low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (patients with nil urine output), or aortic stenosis (heart valve problem).
  • Inform your doctor if you have had a heart attack, diabetes, kidney disease or liver disease
  • Consult your doctor if you are pregnant, planning to get pregnant or breastfeeding.
  • Do not consume alcohol with MACPRIL H 2.5MG TABLET as it may increase the risk of low blood pressure.
  • Avoid potassium supplements with MACPRIL H 2.5MG TABLET as they may lead to high potassium levels in the blood
  • Let your doctor know if you are taking any other medicines, including supplements or herbal products.

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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How does the drug interact with Macpril H 2.5mg Tablet:
Taking Cisapride and Macpril H 2.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Macpril H 2.5mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Macpril H 2.5mg Tablet:
Taking Dofetilide and Macpril H 2.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Macpril H 2.5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macpril H 2.5mg Tablet:
Taking aliskiren together with Macpril H 2.5mg Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Macpril H 2.5mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Macpril H 2.5mg Tablet:
Co-administration of Dronedarone and Macpril H 2.5mg Tablet can increase the risk of severe irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dronedarone and Macpril H 2.5mg Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Macpril H 2.5mg Tablet:
The combined use of Tizanidine and Macpril H 2.5mg Tablet can have additive effects in lowering your blood pressure.

How to manage the interaction:
Taking Tizanidine and Macpril H 2.5mg Tablet together can possibly result in an interaction, but they can be taken if advised by your doctor. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideAminolevulinic acid
Severe
How does the drug interact with Macpril H 2.5mg Tablet:
Coadministration of Aminolevulinic acid with Macpril H 2.5mg Tablet can make your skin more sensitive to bright lights. This could increase the risk or severity of developing a sunburn.

How to manage the interaction:
Although there is a possible interaction between Aminolevulinic acid and Macpril H 2.5mg Tablet, it can be taken if advised by your doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Do not stop using any medications without a doctor's advice.
How does the drug interact with Macpril H 2.5mg Tablet:
Coadministration of Lithium and Macpril H 2.5mg Tablet can increase the effects of lithium.

How to manage the interaction:
Taking Lithium and Macpril H 2.5mg Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Macpril H 2.5mg Tablet:
Co-administration of Droperidol and Macpril H 2.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Droperidol and Macpril H 2.5mg Tablet together can possibly result in an interaction, but they can be taken if advised by your doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.
How does the drug interact with Macpril H 2.5mg Tablet:
Co-administration of Arsenic trioxide and Macpril H 2.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Arsenic trioxide and Macpril H 2.5mg Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Macpril H 2.5mg Tablet:
The combined use of Pimozide and Macpril H 2.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Pimozide and Macpril H 2.5mg Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+RAMIPRIL-2.5MGPotassium rich foods
Moderate

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+RAMIPRIL-2.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consumption of high potassium diet with Macpril H 2.5mg Tablet can cause high levels of potassium in blood. Avoid high potassium diet while being treated with Macpril H 2.5mg Tablet.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
  • Including heart-healthy omega-3 fatty acid acid-containing foods in your daily diet.
  • Use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Caution

MACPRIL H 2.5MG TABLET may enhance the hypotensive (low blood pressure) effect if alcohol is taken along with it. For better advice, you should consult your doctor about whether you can take MACPRIL H 2.5MG TABLET with alcohol.

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Pregnancy

Unsafe

The use of MACPRIL H 2.5MG TABLET or any ACE inhibitors (Ramipril) is usually contraindicated during the second and third trimesters of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using MACPRIL H 2.5MG TABLET.

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Breast Feeding

Caution

Use of MACPRIL H 2.5MG TABLET is not recommended during the breastfeeding stage.

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Driving

Caution

Drive with caution, MACPRIL H 2.5MG TABLET may cause blurry vision, and dizziness or weariness may occur.

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Liver

Caution

Rare elevation in the liver enzymes (like bilirubin) has been observed while taking MACPRIL H 2.5MG TABLET, so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.

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Kidney

Caution

MACPRIL H 2.5MG TABLET to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. MACPRIL H 2.5MG TABLET should be given with precaution in hemodialysis conditions.

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Children

Caution

MACPRIL H 2.5MG TABLET is not recommended for children. The safety and effectiveness of MACPRIL H 2.5MG TABLET have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give MACPRIL H 2.5MG TABLET or not.

FAQs

MACPRIL H 2.5MG TABLET is used to treat hypertension (high blood pressure).

MACPRIL H 2.5MG TABLET contains Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretic or water pill). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers high blood pressure by blocking a naturally occurring substance known as angiotensin II (which tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes.

Yes, MACPRIL H 2.5MG TABLET can cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking MACPRIL H 2.5MG TABLET. In case you feel dizzy or lightheaded, it is recommended to rest for some time until you feel better.

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

If you forget to take MACPRIL H 2.5MG TABLET at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.

Yes, in some cases, MACPRIL H 2.5MG TABLET may affect your serum potassium level, so consult your doctor before using potassium supplements or its salt substitutes.

MACPRIL H 2.5MG TABLET should not be used if you have a history of a serious allergic reaction, including swelling of the face/lips/tongue/throat (angioedema) and an inability to pass urine. Before going outdoor in the sun, try to wear sunscreen (SPF) and avoid sunlamps and tanning booths as prolonged intake of MACPRIL H 2.5MG TABLET may cause your skin to be sensitive to the sunlight.

Yes, if you have diabetes, MACPRIL H 2.5MG TABLET may change your blood sugar level, so check your blood sugar regularly as directed. Tell your doctor if you have high blood sugar (hyperglycemia) symptoms like increased thirst/urination or signs of low blood sugar (hypoglycemia) such as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Your doctor might adjust your dose of MACPRIL H 2.5MG TABLET.

The common side effects of MACPRIL H 2.5MG TABLET include headaches, tiredness, slow heart rate, and nausea. Most of these side effects gradually resolve over time; however, if they persist, please inform your doctor.

No, you should not stop treatment with MACPRIL H 2.5MG TABLET even if you feel an improvement in your symptoms because high blood pressure often has no symptoms and can shoot up at any time. Continue taking it for as long as it has been advised by your doctor.

Yes, you can take MACPRIL H 2.5MG TABLET every day if advised by the doctor. Just make sure to follow your doctor’s instructions regarding how long to use it. Taking it for years on your own without your doctor’s approval could be fatal.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - MAC0052

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