Macpril H 5 Tablet 10's
MRP ₹174.5
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₹26.2 Cashback (15%)
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Genuine Products
Composition :
HYDROCHLOROTHIAZIDE-12.5MG + RAMIPRIL-5MG
Manufacturer/Marketer :
Macleods Pharmaceuticals Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
About MACPRIL H 5MG TABLET
MACPRIL H 5MG TABLET is used to treat blood pressure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.
MACPRIL H 5MG TABLET contains Ramipril and Hydrochlorothiazide. Ramipril relaxes the blood vessels and improves blood flow. Hydrochlorothiazide works by increasing the amount of urine passed out from the kidneys.
Sometimes, you may experience headaches, tiredness, a slow heart rate, and nausea. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Do not take MACPRIL H 5MG TABLET if you are allergic to any of its components. MACPRIL H 5MG TABLET is not recommended in pregnancy and lactation. Keep your doctor informed about your health condition and medications to prevent any interactions.
Uses of MACPRIL H 5MG TABLET
MACPRIL H 5MG TABLET is used in the treatment of Hypertension (high blood pressure). The detailed uses of MACPRIL H 5MG TABLET are as follows:
- Hypertension (High Blood Pressure): MACPRIL H 5MG TABLET controls blood pressure when single-drug therapy isn’t enough.
- Prevention of Cardiovascular Events: MACPRIL H 5MG TABLET lowers risk of heart attack, stroke, and heart failure.
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Directions for Use
- Take MACPRIL H 5MG TABLET with or without food as advised by your doctor.
- It is advised to take MACPRIL H 5MG TABLET once daily in the morning; however, follow your doctor’s recommendation regarding the dosage and duration.
- Swallow MACPRIL H 5MG TABLET as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
- MACPRIL H 5MG TABLET contains Ramipril and Hydrochlorothiazide, which lower and maintain healthy blood pressure levels.
- By controlling hypertension, it helps prevent serious cardiovascular events such as heart attack, stroke, and heart failure.
- Ramipril, an ACE inhibitor, blocks the production of angiotensin II, which relaxes and widens blood vessels to improve blood flow.
- Hydrochlorothiazide acts as a diuretic, increasing urine output to remove extra salt and water from the body, thereby reducing fluid retention (oedema).
- By lowering both blood pressure and fluid buildup, MACPRIL H 5MG TABLET helps the heart pump blood more efficiently.
- It helps relieve swelling associated with heart, liver, kidney, or lung disorders by reducing excess fluid accumulation.
- The combined action of both ingredients maintains optimal circulation and prevents strain on the heart and arteries.
How MACPRIL H 5MG TABLET Works
MACPRIL H 5MG TABLET contains two medicines: Ramipril (blood pressure-lowering agent) and Hydrochlorothiazide (diuretic or water pill). Ramipril is an angiotensin-converting enzyme or ACE inhibitor that lowers high blood pressure by blocking a naturally occurring substance known as angiotensin II (which tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. On the other hand, Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure and reduce the chances of heart attacks or strokes.
Storage
• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Macpril H 5 Tablet
Dealing with Medication-Induced Headache:
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
- Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
- When standing up, do so slowly and carefully to avoid sudden dizziness.
- Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
- Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
- If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
- Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
- If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
- Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
- To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
- Regularly track your symptoms and report any changes or concerns to your healthcare provider.
- Add legumes, whole grains, fruits, vegetables, nuts and seeds in your diet.
- Limit refined carbohydrates, sugary drinks and processed foods.
- Eat healthy fats such as olive oil, avocado and nuts in moderate amounts.
- Choose poultry, fish and lean meat sources.
- To control calorie intake, pay attention to serving sizes.
- Do regular exercise for 150 minutes per week, like cycling, walking or swimming.
- Aim for weight loss if you are overweight as even losing small amount of weight can have a big impact on glucose intolerance.
- Quit smoking and limit alcohol consumption.
- Get sufficient sleep to support hormone regulation and overall health.
What if I have taken an overdose of MACPRIL H 5MG TABLET
An overdose of MACPRIL H 5MG TABLET may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.
Drug Warnings
- Do not take MACPRIL H 5MG TABLET if you are allergic to any of its components, or if you have low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (patients with nil urine output), or aortic stenosis (heart valve problem).
- Inform your doctor if you have had a heart attack, diabetes, kidney disease or liver disease
- Consult your doctor if you are pregnant, planning to get pregnant or breastfeeding.
- Do not consume alcohol with MACPRIL H 5MG TABLET as it may increase the risk of low blood pressure.
- Avoid potassium supplements with MACPRIL H 5MG TABLET as they may lead to high potassium levels in the blood
- Let your doctor know if you are taking any other medicines, including supplements or herbal products.
Drug-Drug Interactions
Critical
HydrochlorothiazideDofetilide
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Macpril H 5 Tablet:
Taking Cisapride and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Macpril H 5 Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Cisapride and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Macpril H 5 Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Macpril H 5 Tablet:
Taking Dofetilide and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Macpril H 5 Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Dofetilide and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Macpril H 5 Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macpril H 5 Tablet:
Taking aliskiren together with Macpril H 5 Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.
How to manage the interaction:
Taking Macpril H 5 Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
Taking aliskiren together with Macpril H 5 Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.
How to manage the interaction:
Taking Macpril H 5 Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Macpril H 5 Tablet:
Coadministration of Lithium and Macpril H 5 Tablet can increase the effects of lithium.
How to manage the interaction:
Taking Lithium and Macpril H 5 Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Coadministration of Lithium and Macpril H 5 Tablet can increase the effects of lithium.
How to manage the interaction:
Taking Lithium and Macpril H 5 Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Macpril H 5 Tablet:
Coadministration of Amiodarone together with Macpril H 5 Tablet may raise the risk of an abnormal heart rhythm.
How to manage the interaction:
Even though Amiodarone and Macpril H 5 Tablet interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.
Coadministration of Amiodarone together with Macpril H 5 Tablet may raise the risk of an abnormal heart rhythm.
How to manage the interaction:
Even though Amiodarone and Macpril H 5 Tablet interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macpril H 5 Tablet:
Taking Ziprasidone and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Ziprasidone and Macpril H 5 Tablet together is avoided as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
Taking Ziprasidone and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Ziprasidone and Macpril H 5 Tablet together is avoided as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macpril H 5 Tablet:
The combined use of Pimozide and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Pimozide and Macpril H 5 Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.
The combined use of Pimozide and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Pimozide and Macpril H 5 Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDroperidol
Severe
How does the drug interact with Macpril H 5 Tablet:
Co-administration of Droperidol and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Droperidol and Macpril H 5 Tablet together can possibly result in an interaction, but they can be taken if advised by your doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.
Co-administration of Droperidol and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Droperidol and Macpril H 5 Tablet together can possibly result in an interaction, but they can be taken if advised by your doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.
How does the drug interact with Macpril H 5 Tablet:
Co-administration of Arsenic trioxide and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Arsenic trioxide and Macpril H 5 Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Arsenic trioxide and Macpril H 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Arsenic trioxide and Macpril H 5 Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDolasetron
Severe
How does the drug interact with Macpril H 5 Tablet:
Co-administration of Dolasetron and Macpril H 5 Tablet can affect the rhythm of your heart which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Dolasetron and Macpril H 5 Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision, nausea, and seizures, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Dolasetron and Macpril H 5 Tablet can affect the rhythm of your heart which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Dolasetron and Macpril H 5 Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision, nausea, and seizures, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
HYDROCHLOROTHIAZIDE-12.5MG+RAMIPRIL-5MGPotassium rich foods
Moderate
Drug-Food Interactions
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HYDROCHLOROTHIAZIDE-12.5MG+RAMIPRIL-5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt
How to manage the interaction:
Consumption of high potassium diet with Macpril H 5 Tablet can cause high levels of potassium in blood. Avoid high potassium diet while being treated with Macpril H 5 Tablet.
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt
How to manage the interaction:
Consumption of high potassium diet with Macpril H 5 Tablet can cause high levels of potassium in blood. Avoid high potassium diet while being treated with Macpril H 5 Tablet.
Diet & Lifestyle Advise
- Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
- Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.
- Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
- Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
- If you are taking alcohol, then only one serving for women and two servings is advisable.
- Quitting smoking is the best strategy to lower the risk of heart disease.
- Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
- Including heart-healthy omega-3 fatty acid acid-containing foods in your daily diet.
- Use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.
Habit Forming
No
Therapeutic Class
ANTI- HYPERTENSIVES
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Alcohol
Caution
MACPRIL H 5MG TABLET may enhance the hypotensive (low blood pressure) effect if alcohol is taken along with it. For better advice, you should consult your doctor about whether you can take MACPRIL H 5MG TABLET with alcohol.
Pregnancy
Unsafe
The use of MACPRIL H 5MG TABLET or any ACE inhibitors (Ramipril) is usually contraindicated during the second and third trimesters of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using MACPRIL H 5MG TABLET.
Breast Feeding
Caution
Use of MACPRIL H 5MG TABLET is not recommended during the breastfeeding stage.
Driving
Caution
Drive with caution, MACPRIL H 5MG TABLET may cause blurry vision, and dizziness or weariness may occur.
Liver
Caution
Rare elevation in the liver enzymes (like bilirubin) has been observed while taking MACPRIL H 5MG TABLET, so it must be taken with caution. If you have a history of liver diseases/conditions, the dose may have to be adjusted by your doctor.
Kidney
Caution
MACPRIL H 5MG TABLET to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. MACPRIL H 5MG TABLET should be given with precaution in hemodialysis conditions.
Children
Caution
MACPRIL H 5MG TABLET is not recommended for children. The safety and effectiveness of MACPRIL H 5MG TABLET have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give MACPRIL H 5MG TABLET or not.
Heart
MACPRIL H 5MG TABLET is safe for use in heart patients if recommended by the physician.
Geriatrics
Caution
MACPRIL H 5MG TABLET should be used under caution in geriatric patients. Please consult your physician.
FAQs
Country of origin
India
Manufacturer/Marketer address
Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - MAC0048
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