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compositionComposition:GABAPENTIN-300MG+MECOBALAMIN-500MCG
prescription
Prescription Medicine
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Macrobion-G Tab is used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia and restless leg syndrome in adults and children above 3 years of age. It contains Gabapentin and Mecobalamin (a form of vitamin B12), which decreases the abnormal excitement of chemical messenger in the brain. Also, it helps rejuvenate and protect damaged nerve cells. Thus, it provides relief from neuropathic pain caused due to nerve damage and other neurological disorders. It may cause side effects such as dizziness, tiredness, sleepiness and uncoordinated body movements. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

GABAPENTIN-300MG+MECOBALAMIN-500MCG

Manufacturer/Marketer :

Crossed Fingers Organics Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Macrobion-G Tab

Macrobion-G Tab is an oral prescription medication primarily used to manage neuropathic pain, which is chronic pain caused by nerve damage. This type of discomfort often occurs due to conditions like diabetes, shingles, or spinal cord injuries. By targeting the damaged nerves, Macrobion-G Tab helps reduce abnormal pain signals and supports nerve recovery.

For the best results, you should take Macrobion-G Tab regularly at the same times every day as directed by your doctor. You can take this oral medicine with or without food, though taking it with a meal may help if you experience a mild upset stomach. Combining this treatment with a balanced diet rich in B-vitamins and regular, low-impact exercise can significantly improve your recovery.

While taking Macrobion-G Tab , you might experience mild side effects like drowsiness, dizziness, or tiredness. These effects are usually temporary as your body adjusts, but you should contact your doctor immediately if you notice severe mood changes, swelling in your hands or feet, or difficulty breathing.

Before starting Macrobion-G Tab , tell your doctor if you have kidney disease, a history of depression or mood disorders, or any allergies. Do not take this if you have had a severe allergic reaction to any of its active components in the past.

Macrobion-G Tab can interact with alcohol, certain antacids, and sleeping pills, which may increase drowsiness or reduce its effectiveness. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor or pharmacist to ensure this medication is safe for you.

Uses of Macrobion-G Tab

Macrobion-G Tab is used in the treatment of neuropathic pain (nerve pain) and epilepsy (seizures). The detailed uses of Macrobion-G Tab are as follows:

  • Neuropathic Pain: Macrobion-G Tab helps relieve chronic nerve pain caused by damaged nerves, commonly manifesting as burning, stabbing, or tingling sensations in the hands and feet.
  • Manages Epilepsy: Macrobion-G Tab contains Gabapentin (an anticonvulsant), which helps control seizures (fits) by stabilising electrical activity in the brain and calming overactive nerves.
  • Diabetic Neuropathy: It targets nerve damage caused by chronic high blood sugar levels in diabetes, reducing persistent discomfort and improving daily functioning.
  • Postherpetic Neuralgia: It manages the severe, lingering nerve pain that can persist after a shingles infection has cleared.
  • Nutritional Support for Nerves: The medication helps regenerate injured nerves and restores the protective sheath around them to prevent further nerve damage.
     

Key Benefits

Macrobion-G Tab helps relieve nerve-related pain and supports the recovery of damaged nerves, improving comfort and overall quality of life. Combining pain relief with nutritional support for nerve health helps you stay active and perform daily activities more comfortably. Benefits may include:

  • Helps relieve burning, shooting, tingling, and other symptoms of nerve pain.
  • Supports the repair and regeneration of damaged nerves.
  • Helps improve nerve function and overall nervous system health.
  • Reduces nighttime nerve pain, promoting better sleep quality.
  • Improves daily comfort, mobility, and productivity.
  • Provides long-term support for nerve health while helping manage pain symptoms.
     
Side effects of Macrobion-G Tab
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Take Macrobion-G Tab with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

How Macrobion-G Tab Works

Macrobion-G Tab contains Gabapentin and Mecobalamin. • Gabapentin: It helps relieve nerve pain by reducing the pain signals sent from damaged nerves to the brain. This helps decrease burning, tingling, stabbing pain, and discomfort. • Mecobalamin: It is an active form of vitamin B12 that helps repair and nourish damaged nerves. It supports nerve regeneration, improves nerve function, and helps prevent further nerve damage.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Macrobion-G Tab as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking Macrobion-G Tab if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Macrobion-G Tab ; your doctor will decide whether Macrobion-G Tab can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Macrobion-G Tab causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Macrobion-G Tab should not be given to children less than 3 years of age. For the above 3 years of age, close monitoring is required.

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Heart

Caution

Macrobion-G Tab should be taken with extreme caution in patients with heart disease. Please consult your physician.

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Geriatrics

Caution

Macrobion-G Tab should be used with extreme caution in elderly patients due to an increased risk of adverse effects. Dose adjustments maybe needed in some patients.

What if I have taken an overdose of Macrobion-G Tab

If you or someone else takes too much of Macrobion-G Tab , seek immediate medical attention or contact your local emergency services. Symptoms of an overdose may include extreme drowsiness, severe dizziness, slurred speech, or double vision.

Diet & Lifestyle Advise

  • Eat B-vitamin rich foods: Include green leafy vegetables, eggs, lean meats, and fish in your diet to support your nerve health alongside this medication.
  • Manage blood sugar levels: If you have diabetes, keeping your blood sugar within target ranges is crucial to prevent further nerve damage.
  • Engage in low-impact exercise: Activities like walking, swimming, or gentle stretching can improve blood circulation to your nerves and reduce pain.
  • Avoid alcohol: Drinking alcohol can worsen dizziness and drowsiness caused by the medication and can also worsen nerve damage.
  • Take care of your feet: Inspect your feet daily for cuts, blisters, or redness, as nerve damage can make it harder to feel injuries.
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How Soon It Starts Working

The time required for Macrobion-G Tab to start to work: The time required for Macrobion-G Tab to show its action is unknown.

The time for which the effects of Macrobion-G Tab last: The duration of action for Macrobion-G Tab is unknown.

What if you forget to take Macrobion-G Tab

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not stop treatment abruptly: Do not stop taking Macrobion-G Tab suddenly, as this may cause withdrawal symptoms, worsening nerve pain, or seizures in susceptible individuals. Your doctor will usually recommend gradually reducing the dose if treatment needs to be discontinued.
  • Use caution during activities requiring alertness: Macrobion-G Tab may cause drowsiness, dizziness, or reduced concentration. Avoid driving, operating heavy machinery, or performing tasks that require full mental alertness until you know how it affects you.
  • Take antacids at a different time: If you need to take an antacid containing aluminum or magnesium, take it at least two hours before or after Macrobion-G Tab , as antacids can reduce the absorption of the medicine.
  • Monitor your mood and behavior closely: Contact your healthcare provider immediately if you experience sudden mood changes, worsening depression, anxiety, or thoughts of self-harm.
  • Attend regular monitoring appointments: Patients with kidney impairment may require dose adjustments and regular kidney function tests. Your doctor may modify treatment based on your kidney function over time.
  • Use with caution in certain populations: Older adults may be more sensitive to dizziness, drowsiness, confusion, balance problems, and falls and may require closer monitoring. Macrobion-G Tab should only be used in children when specifically prescribed by a healthcare professional.
  • Take the medicine exactly as prescribed: Cases of misuse and dependence have been reported with gabapentin, particularly in people with a history of substance misuse or when used with opioid medicines. Do not increase the dose or use the medicine more often than prescribed.
  • Do not share your medication: Macrobion-G Tab requires individualized dosing and monitoring and should not be given to anyone else, even if they have similar symptoms.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Antacids (e.g., aluminium, magnesium): Taking these medicines alongside Macrobion-G Tab may reduce its absorption and effectiveness. Take them at least two hours apart.
  • Opioid pain relievers (e.g., morphine): Combining these with Macrobion-G Tab may increase the risk of severe drowsiness, dizziness, and slow or shallow breathing.
  • Sleeping pills and anti-anxiety medicines: Taking these alongside Macrobion-G Tab may enhance its sedative effects, leading to excessive sleepiness and impaired alertness.

Drug-Food Interactions

  • Alcohol: Avoid consuming alcohol while taking Macrobion-G Tab , as it can significantly increase drowsiness, dizziness, coordination problems, and may worsen nerve-related symptoms.

Drug-Disease Interactions

  • Kidney disease: Patients with impaired kidney function may clear Macrobion-G Tab more slowly, increasing the risk of drug accumulation and side effects. Lower doses may be required.
  • Depression or mood disorders: Macrobion-G Tab may increase the risk of suicidal thoughts or behavioral changes in some individuals and may require closer monitoring during treatment.
     
Mecobalamin + GabapentinKetamine
Severe
Mecobalamin + GabapentinOxycodone
Severe

Drug-Drug Interactions

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Mecobalamin + GabapentinKetamine
Severe
How does the drug interact with Macrobion-G Tab:
Using ketamine together with gabapentin may increase the risk of side effects.

How to manage the interaction:
Although taking Ketamine and Gabapentin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, and respiratory depression consult a doctor right away. Do not discontinue any medications without consulting a doctor.
Mecobalamin + GabapentinOxycodone
Severe
How does the drug interact with Macrobion-G Tab:
Using Gabapentin together with Oxycodone can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Gabapentin with Oxycodone together can result in an interaction, but it can be taken if a doctor has advised it. If you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact a doctor right away. Do not stop using any medications without a doctor's advice.
Mecobalamin + GabapentinSodium oxybate
Severe
How does the drug interact with Macrobion-G Tab:
Using Gabapentin together with Sodium oxybate can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Sodium oxybate, it can be taken if prescribed by a doctor. If you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Mecobalamin + GabapentinSufentanil
Severe
How does the drug interact with Macrobion-G Tab:
Using Gabapentin together with Sufentanil can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Sufentanil, it can be taken if prescribed by a doctor. If you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Mecobalamin + GabapentinBuprenorphine
Severe
How does the drug interact with Macrobion-G Tab:
Co-administration of Buprenorphine and Gabapentin may cause central nervous system depression and lead to serious side effects (respiratory distress -build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Buprenorphine, you can take these medicines together if prescribed by a doctor. However, if you experience any unusual symptoms consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Mecobalamin + GabapentinAlfentanil
Severe
How does the drug interact with Macrobion-G Tab:
Using Gabapentin together with Alfentanil can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Alfentanil, it can be taken if prescribed by a doctor. If you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Mecobalamin + GabapentinRemifentanil
Severe
How does the drug interact with Macrobion-G Tab:
Using Gabapentin together with Remifentanil can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Gabapentin with Remifentanil together can result in an interaction, but it can be taken if a doctor has advised it. If you experience trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Mecobalamin + GabapentinEsketamine
Severe
How does the drug interact with Macrobion-G Tab:
Coadministration of Gabapentin with Esketamine can increase the risk of serious side effects.

How to manage the interaction:
Although taking Gabapentin and Esketamine together can cause an interaction, it can be taken if a doctor has suggested it. Consult a doctor if you experience any symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not stop using any medications without a doctor's advice.
Mecobalamin + GabapentinButorphanol
Severe
How does the drug interact with Macrobion-G Tab:
Co-administration of Butorphanol and Gabapentin may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Butorphanol, you can take these medicines together if prescribed by a doctor. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Mecobalamin + GabapentinPethidine
Severe
How does the drug interact with Macrobion-G Tab:
Using Gabapentin together with Pethidine can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Pethidine with Gabapentin can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Macrobion-G Tab is used to treat neuropathic pain. It helps rejuvenate and protect damaged nerve cells by producing a substance called myelin.
If Macrobion-G Tab is taken along with antacid medicines containing aluminium and magnesium, it may lower the stomach's absorption of Macrobion-G Tab . To avoid this, maintain a gap of two hours between Macrobion-G Tab and antacid medicines.
The nerves in the periphery of your body, like the nerves in your fingertip and toes are known as peripheral nerves, and any injury to one or more of these nerves is known as peripheral neuropathy. These nerves transmit messages from/to the brain and spinal cord to/from the rest of the body. Damage caused to these nerves stops them from working properly, and the messages moving between your central and peripheral nervous system get disturbed.
Macrobion-G Tab is not a sedative drug. However, it has been known to cause drowsiness and sleepiness. You should not take up activities like driving and activities which require mental alertness along with physical coordination.
Yes, Macrobion-G Tab may rarely cause weight gain, but is not experienced by every one. Follow regular diet and exercise in order to maintain healthy weight.
Neuropathic pain is a nervous system disorder from damage to sensory nerves, often due to chronic nerve disease, infection, or injury. The pain may be constant or come and go, and is often described as prickling, stabbing, tingling, or burning. Numbness and loss of sensation are also common symptoms associated with this type of pain. While muscle pain is usually a dull, aching, or throbbing pain, often related to overuse or strain.
Avoid Macrobion-G Tab if you are allergic to the active substances. Macrobion-G Tab is not recommended for children under 3, and may cause behavioural changes in ages 3 to 12. Consult your doctor if pregnant, breastfeeding, or if you experience suicidal thoughts.
You are recommended not to stop taking Macrobion-G Tab without consulting your doctor as stopping it suddenly can cause withdrawal symptoms. Therefore, continue taking Macrobion-G Tab for the duration prescribed and if you experience any difficulty while taking Macrobion-G Tab , consult your doctor so that the dose may be reduced gradually.
No, do not take higher than the recommended dose of Macrobion-G Tab as it can lead to dizziness, double vision, slurred speech, drowsiness, loss of consciousness, diarrhoea. However, if you experience these symptoms, consult your doctor.
Store Macrobion-G Tab at room temperature as advised on the label. Protect from moisture. Keep it out of reach of children.
Macrobion-G Tab causes side effects such as dizziness, tiredness, sleepiness, and uncoordinated body movement. These do not require any medical treatment as they will gradually reduce over time. Please consult the doctor if these side effects persist for longer durations.
It is highly recommended to avoid alcohol while taking Macrobion-G Tab . Alcohol can worsen side effects like dizziness, drowsiness, and lack of coordination, and it can also interfere with nerve recovery. Talk to your doctor if you have concerns.
Some people may begin to feel relief within a couple of weeks, while for others, it may take a few weeks of consistent use to notice a significant improvement in nerve pain. Always follow your prescribed regimen. Talk to your doctor if you do not notice any improvement after a few weeks.
Macrobion-G Tab should only be used during pregnancy or breastfeeding if your doctor decides that the benefits outweigh the risks. There is limited data on its safety for unborn babies and infants. Talk to your doctor to discuss safer alternatives.
Gabapentin is primarily removed from the body through the kidneys. If kidney function is reduced, the medicine can accumulate and increase the risk of side effects such as excessive drowsiness, dizziness, and confusion. Your doctor may use kidney function tests to determine the safest dose for you.
Most people use Macrobion-G Tab safely as prescribed. However, gabapentin has been associated with misuse and dependence in some individuals, particularly those with a history of substance misuse. Always take the medicine exactly as prescribed and do not share it with others.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

No. 81- B, Epip, Phase-1, Jharmajri, Baddi, Baddi - 173205
Other Info - MAC0317

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