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Magnesium Sulphate 2 Ml 25% is used to treat magnesium deficiency and to control and prevent seizures in severe pre-eclampsia and eclampsia. It contains magnesium sulphate, which works by increasing the amount of magnesium levels in the blood and prevents or controls convulsions by blocking neuromuscular transmission. Common side effects include pain, swelling and redness at the site of application, nausea, vomiting, and drowsiness. Inform your doctor if you are allergic to any of its components, if you are pregnant, breastfeeding or taking any other medications.

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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Magnesium Sulphate 2 Ml 25%

Magnesium Sulphate 2 Ml 25% is a prescription injection used to treat and prevent critically low mineral levels in the body. It is also commonly used to prevent or control seizures in pregnant individuals experiencing severe pre-eclampsia or eclampsia. This sterile solution is delivered directly into a muscle or vein under professional medical supervision.

Since this medicine is given as an injection or infusion, its frequency and duration depend entirely on your specific medical condition and blood test results. It is typically given in a hospital or clinic setting, meaning you do not need to worry about taking it with food. For long-term management of your mineral balance, your doctor may recommend eating nutrient-rich foods such as leafy green vegetables, nuts, seeds, and whole grains once you are discharged.

While receiving Magnesium Sulphate 2 Ml 25%, you may experience temporary side effects such as warmth, flushing, sweating, or mild discomfort at the injection site. These effects are usually temporary. However, tell your healthcare provider immediately if you experience serious symptoms such as muscle weakness, slow breathing, a sudden drop in blood pressure, or a slow heart rate.

Before receiving this injection, tell your doctor if you have kidney problems, heart conditions, or muscle disorders such as myasthenia gravis. Do not receive this medicine if you have severe heart block or serious kidney damage unless your doctor determines that it is absolutely necessary.

Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, herbal products, and supplements you are taking before receiving this injection. Certain antibiotics, blood pressure medicines, and muscle relaxants may interact with this medicine and increase the risk of muscle weakness or breathing difficulties. If you are pregnant, breastfeeding, or an older adult, your doctor will carefully monitor your treatment to ensure your safety.
 

Uses of Magnesium Sulphate 2 Ml 25%

Your doctor may prescribe Magnesium Sulphate 2 Ml 25% to help manage the following conditions:

  • Severe low magnesium levels: Rapidly restores healthy magnesium levels in the blood when oral supplements are not enough or cannot be taken.
  • Pre-eclampsia and eclampsia: Helps prevent and control life-threatening seizures in pregnant individuals with dangerously high blood pressure.
  • Irregular heartbeats: Helps stabilise the electrical activity of the heart in specific life-threatening heart rhythm emergencies.
  • Paediatric kidney inflammation: Is sometimes used to control high blood pressure-related seizures in children with severe kidney inflammation.
     

Key Benefits

Magnesium Sulphate 2 Ml 25% provides rapid treatment by delivering magnesium directly into the bloodstream or muscle when immediate correction is needed.

  • Rapidly restores magnesium levels: Helps quickly correct severe magnesium deficiency when oral supplements are not suitable or cannot be absorbed.
  • Helps prevent serious complications: Prompt treatment helps reduce the risk of complications associated with severe magnesium deficiency, including muscle spasms and certain heart rhythm disturbances.
  • Helps prevent seizures in pre-eclampsia and eclampsia: By calming overactive nerve activity, it helps prevent and control life-threatening seizures during severe pregnancy-related high blood pressure.
  • Supports normal nerve, muscle, and heart function: Restoring magnesium levels helps normalise nerve signalling, muscle function, and the heart's electrical activity.
     

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Magnesium Sulphate 2 Ml 25% is administered by the doctor or healthcare professional.
  • Do not self-administer.

How Magnesium Sulphate 2 Ml 25% Works

Magnesium Sulphate 2 Ml 25% contains magnesium sulphate, which supplies magnesium, an essential mineral that your body needs for the normal functioning of nerves, muscles, and the heart. After administration, magnesium sulphate helps restore low magnesium levels in the body. It acts as a natural blocker of certain chemical signals in the nervous system, helping prevent excessive nerve activity that can trigger seizures or severe muscle spasms. It also helps relax blood vessels and stabilise the heart's electrical activity, which can help lower dangerously high blood pressure in women with severe pre-eclampsia and support the treatment of certain life-threatening heart rhythm problems.
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Alcohol

Consult your doctor

It is not known if alcohol affects Magnesium Sulphate 2 Ml 25%. However, avoid consumption of alcohol during treatment with Magnesium Sulphate 2 Ml 25%, as it may increase dizziness and drowsiness.

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Pregnancy

Safe if prescribed

Magnesium Sulphate 2 Ml 25% is used to treat seizures during pregnancy. However, please consult your doctor before receiving Magnesium Sulphate 2 Ml 25% if you are pregnant.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding or if you are having any concerns regarding this. The doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Magnesium Sulphate 2 Ml 25% is unlikely to affect the ability to drive and use machines. However, some people may feel dizzy or drowsy after receiving Magnesium Sulphate 2 Ml 25%. If you experience these side effects, do not drive or use machines.

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Liver

Consult your doctor

Please consult your doctor if you have liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment.

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Children

Consult your doctor

Please consult the doctor if you have any concerns regarding the usage of Magnesium Sulphate 2 Ml 25% in children.

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Heart

Caution

Magnesium Sulphate 2 Ml 25% is contraindicated for patients with heart block or myocardial damage. Therefore, please inform your doctor if you have any heart problems before prescribing Magnesium Sulphate 2 Ml 25%.

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Geriatrics

Consult your doctor

Magnesium Sulphate 2 Ml 25% may require dose adjustment in geriatric patients due to impaired renal (kidney) function. Therefore, please consult your doctor before using Magnesium Sulphate 2 Ml 25%.

What if I have taken an overdose of Magnesium Sulphate 2 Ml 25%

An overdose of this injection can be very serious and may lead to severe muscle weakness, slow breathing, or heart problems. Because this medicine is usually given by trained healthcare professionals, an overdose is uncommon. However, if an overdose is suspected or if you experience extreme sleepiness, severe muscle weakness, or breathing difficulties, seek immediate medical attention or go to the nearest emergency department without delay.

Diet & Lifestyle Advise

  • Eat magnesium-rich foods: Include leafy green vegetables, nuts, seeds, legumes, and whole grains in your diet to help maintain healthy magnesium levels naturally after your acute treatment is complete.
  • Limit processed foods and fizzy drinks: Excessive intake of processed foods and carbonated soft drinks may interfere with your body's ability to maintain healthy mineral levels.
  • Monitor your blood pressure if advised: If you are recovering from pre-eclampsia, check your blood pressure regularly at home as instructed by your doctor.
  • Stay well hydrated: Drink enough water unless your doctor has advised you to limit your fluid intake because of kidney or heart problems.
  • Avoid excessive alcohol and caffeine: Large amounts of alcohol and caffeine may increase the loss of magnesium through the kidneys over time.
     
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How Soon It Starts Working

The time required for Magnesium Sulphate 2 Ml 25% to start to work: The time required for Magnesium Sulphate 2 Ml 25% to start to work is 30 minutes after administration. The time for which the effects of Magnesium Sulphate 2 Ml 25% last: The effect of Magnesium Sulphate 2 Ml 25% lasts for 3 to 4 hours.

What if you forget to take Magnesium Sulphate 2 Ml 25%

Since this medicine is usually given by a healthcare professional in a hospital or clinic, it is highly unlikely that you will miss a dose. If you are receiving treatment at home and miss a scheduled appointment or dose, contact your doctor or healthcare provider immediately for further instructions.

Storage

• Store Magnesium Sulphate 2 Ml 25% at controlled room temperature, preferably between 20°C and 25°C, or according to the storage instructions on the product label.

Drug Warnings

  • Inspect the solution before use: The solution should be completely clear and colourless without any visible particles before it is administered.
  • Rotate injection sites if receiving intramuscular injections: If this medicine is being injected into a muscle, rotating the injection site may help reduce pain and minimise tissue damage.
  • Never reuse needles or syringes: Used needles and syringes should always be disposed of safely in an approved puncture-resistant sharps container.
  • Regular monitoring is essential: Your healthcare team should regularly check your knee-jerk reflexes, breathing rate, and overall response during treatment because these are important safety checks while receiving magnesium sulphate.
  • Report reduced urine output promptly: Tell your doctor immediately if you notice that you are passing much less urine than usual during treatment.
     

Drug-Drug Interactions

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  • Calcium channel blockers (such as nifedipine): Taking these medicines together may increase the risk of dangerously low blood pressure and severe muscle weakness.
  • Neuromuscular blockers (muscle relaxants used during surgery): Magnesium sulphate may increase the effects of these medicines, leading to prolonged muscle relaxation or breathing difficulties.
  • Certain antibiotics (such as aminoglycosides): Using these medicines together may increase the risk of severe muscle weakness and nerve-related problems.
  • Medicines that slow brain activity, such as opioids or sedatives: Taking these medicines together may increase the risk of excessive drowsiness and slow breathing.
     

Drug-Drug Interactions

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How does the drug interact with Magnesium Sulphate 2 Ml 25%:
Taking Magnesium Sulphate 2 Ml 25% with Streptomycin can increase the risk of muscle weakness.

How to manage the interaction:
Although taking Magnesium Sulphate 2 Ml 25% and Streptomycin together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as muscle weakness and shortness of breath, chest pain or tightness, excessive sweating, body aches, or muscle stiffness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Magnesium Sulphate 2 Ml 25%:
Taking Magnesium Sulphate 2 Ml 25% with tobramycin can increase the risk of muscle weakness.

How to manage the interaction:
Although taking Magnesium Sulphate 2 Ml 25% and Tobramycin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as muscle weakness and breathing difficulties consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Magnesium Sulphate 2 Ml 25%:
Coadministration of Magnesium Sulphate 2 Ml 25% with amikacin can increase the risk of muscle weakness.

How to manage the interaction:
Although taking amikacin and Magnesium Sulphate 2 Ml 25% together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you have muscular weakness or breathing issues. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Magnesium Sulphate 2 Ml 25%:
Taking dolutegravir with Magnesium Sulphate 2 Ml 25% can reduce the effects of Dolutegravir.

How to manage the interaction:
Although taking Dolutegravir and Magnesium Sulphate 2 Ml 25% together can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if your condition gets worse or if you develop new infections while taking these medications, it is important to contact a doctor immediately. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Magnesium Sulphate 2 Ml 25%:
Co-administration of Magnesium Sulphate 2 Ml 25% with Gentamicin can increase the risk of muscle weakness.

How to manage the interaction:
Although there is a possible interaction between Magnesium Sulphate 2 Ml 25% and Gentamicin, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience muscle weakness and breathing difficulties. Do not stop using any medications without talking to a doctor.
How does the drug interact with Magnesium Sulphate 2 Ml 25%:
Taking Magnesium Sulphate 2 Ml 25% with Netilmicin can increase the risk of muscle weakness.

How to manage the interaction:
Although taking Magnesium Sulphate 2 Ml 25% and Netilmicin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as muscle weakness and breathing difficulties consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Magnesium Sulphate 2 Ml 25%:
Taking Magnesium Sulphate 2 Ml 25% with Kanamycin can increase the risk of muscle weakness.

How to manage the interaction:
There may be a possibility of interaction between Magnesium Sulphate 2 Ml 25% and Kanamycin, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as muscle weakness and breathing difficulties, make sure to contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Magnesium Sulphate 2 Ml 25%:
Taking Magnesium Sulphate 2 Ml 25% with Neomycin can increase the risk of muscle weakness.

How to manage the interaction:
Although taking Magnesium Sulphate 2 Ml 25% and Neomycin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as muscle weakness and breathing difficulties consult doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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  • No clinically significant food interactions are known with Magnesium Sulphate 2 Ml 25% when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTICONVULSANT, ELECTROLYTES]

FAQs

Magnesium Sulphate 2 Ml 25% contains magnesium sulphate that works by increasing the amount of magnesium levels in the blood. It also prevents or controls convulsions by blocking neuromuscular transmission and increases the seizure threshold.
Common side effects of Magnesium Sulphate 2 Ml 25% include pain, swelling and redness at the site of application, nausea, vomiting, and drowsiness. Consult the doctor if the side effects persist or worsen.
Inform the doctor if you have kidney or heart problems, stomach or intestinal disorder, or if you are dehydrated.
Magnesium Sulphate 2 Ml 25% is a prescription injection used to treat severe magnesium deficiency and to prevent or control seizures in pregnant individuals with severe pre-eclampsia or eclampsia. It may also be used to treat certain life-threatening heart rhythm disorders. Your doctor can explain why this treatment has been recommended for you.
This medicine is injected into a muscle or given slowly through a drip into a vein (intravenous infusion). It is administered by a trained healthcare professional in a hospital or clinic. Speak with your healthcare provider if you have questions about your treatment schedule.
It is common to experience a temporary feeling of warmth, flushing, or mild sweating during the injection or infusion. These effects usually settle quickly. Tell your doctor or nurse immediately if they become severe or if you develop muscle weakness, slow breathing, or feel faint.
Yes. Magnesium sulphate is commonly used during pregnancy to prevent life-threatening seizures in women with severe pre-eclampsia or eclampsia. However, because prolonged or repeated high-dose treatment may affect your baby's bone development, it is used only under close medical supervision. Your healthcare provider can discuss the expected benefits and possible risks with you.
Because this medicine is given by injection, food does not directly affect how it is absorbed. However, maintaining a balanced diet rich in magnesium-containing foods may help support healthy magnesium levels after your treatment is completed. Your doctor can advise you if you have any specific dietary restrictions.
Tell your doctor if you have kidney disease before receiving this medicine. Reduced kidney function may allow magnesium to build up in your body, increasing the risk of serious side effects. Your doctor may adjust your dose and monitor your blood magnesium levels more closely during treatment.
Excessively high magnesium levels may cause severe muscle weakness, a very slow heartbeat, slow or shallow breathing, extreme drowsiness, severe dizziness, or loss of consciousness. If any of these symptoms occur, seek immediate medical attention without delay.

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Country of origin

INDIA

Manufacturer/Marketer address

Fresenius Kabi AG? , Else-Kröner-Straße 1 ? , 61352 Bad Homburg , Germany
Other Info - MAG0211
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