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compositionComposition:PRIMAQUINE-15MG
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Malirid-DS Tablet is an antimalarial drug used for the treatment of malaria. It contains Primaquine, which kills the malaria parasite and stops the infection from spreading. It helps to prevent the relapse of malaria caused by plasmodium vivax and Plasmodium ovale strains of the parasite. It may cause common side effects such as rash, vomiting, headache, dizziness, stomach pain, nausea, itching, heartburn, and gastrointestinal discomfort.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PRIMAQUINE-15MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Malirid-DS Tablet

Malirid-DS Tablet is a prescription medication used primarily to prevent the relapse of certain types of malaria. It works by targeting malaria parasites that remain dormant in the liver, ensuring the infection is completely cleared from your body. This medication is essential for patients recovering from specific mosquito-borne infections to stop the disease from returning.

To achieve the best results, you must take Malirid-DS Tablet consistently and exactly as prescribed, without skipping any doses, even if you start to feel better. It is typically taken once daily for a specific number of days, and you should always take it with a meal or a glass of milk to help protect your stomach. Along with taking this medicine, getting plenty of rest and staying well-hydrated will support your body's recovery process.

While taking Malirid-DS Tablet, some people may experience mild side effects like nausea or stomach cramps. However, you must contact your doctor immediately if you notice serious signs such as dark-coloured urine, unusual tiredness, or pale skin. These symptoms can indicate a serious blood problem that requires urgent medical evaluation.

Talk to your doctor before starting Malirid-DS Tablet if you have any pre-existing health conditions, especially a genetic enzyme deficiency known as G6PD deficiency. Do not take this if you have G6PD deficiency or if you are pregnant, as the medicine can cause severe blood issues in both you and the unborn baby.

This medicine can interact with other drugs that affect your blood or immune system, so be sure to share your complete medication list with your healthcare provider. Avoid drinking alcohol while on this treatment to prevent excessive stomach irritation and avoid unnecessary strain on your liver. If you are breastfeeding or caring for an elderly patient, talk to your doctor or pharmacist to ensure this medicine is safe to use.

Uses of Malirid-DS Tablet

Malirid-DS Tablet is an antimalarial medicine used to eliminate certain stages of malaria parasites that remain in the body after initial treatment. It helps in:

  • Preventing malaria relapse: It targets and destroys the sleeping stage of malaria parasites hiding in your liver cells, preventing the infection from coming back weeks or months later.
     
  • Stopping malaria transmission: It helps kill the active parasites in your blood that could be picked up by mosquitoes, thereby preventing the spread of the infection to other people in your community.
     

Key Benefits

Malirid-DS Tablet offers several important benefits that help ensure:

  • Helps Prevent Malaria Relapse: Malirid-DS Tablet destroys the dormant liver forms of malaria parasites that are not eliminated by standard antimalarial medicines, helping achieve a complete cure.
  • Reduces the Risk of Future Episodes: By preventing the return of malaria, it helps you recover fully and return to your normal daily activities without the worry of repeated illness.
  • Helps Prevent the Spread of Malaria: By reducing the number of parasites that mosquitoes can transmit, Malirid-DS Tablet helps protect your family, community, and others from infection.
  • Supports Long-Term Recovery: Completing the full course of Malirid-DS Tablet helps ensure that hidden parasites are eliminated, reducing the likelihood of ongoing or recurrent malaria infections.
     
Side effects of Malirid-DS Tablet
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Directions for Use

  • Take Malirid-DS Tablet with food to decrease the risk of stomach upset.
  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Malirid-DS Tablet Works

Malirid-DS Tablet contains primaquine, an antimalarial medicine that helps eliminate malaria parasites and prevent the infection from returning. Malirid-DS Tablet works by targeting malaria parasites that remain dormant in the liver after the initial infection has been treated. It disrupts the parasites' energy production and essential metabolic processes, destroying these hidden parasites before they can become active again and re-enter the bloodstream. Together, these actions help completely clear certain types of malaria parasites from the body, prevent future relapses, and reduce the risk of the infection returning.
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Alcohol

Caution

Interaction of Malirid-DS Tablet with alcohol is unknown. It is advisable to consult your doctor before consumption.

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Pregnancy

Caution

Malirid-DS Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations, if the benefits are more than the potential risks. Please consult your doctor.

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Breast Feeding

Caution

Malirid-DS Tablet is recommended for use in breastfeeding women only after diagnostic tests are performed to confirm normal G6PD enzyme levels. Consult your doctor before using this medicine

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Driving

Caution

Malirid-DS Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

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Liver

Caution

Malirid-DS Tablet therapy is unlikely to cause liver injury in normal individuals but can trigger an acute worsening of porphyria in rare cases. Thus doctor's consultation is recommended before taking Malirid-DS Tablet

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Kidney

Caution

Malirid-DS Tablet administration impairs kidney function in a few cases, so a patient is recommended to consult a doctor before taking Malirid-DS Tablet.

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Children

Caution

Safe to use in children (<12) yet dose adjustment by a doctor will be done on the basis of age, weight and severity of the infection.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Caution

Malirid-DS Tablet can be given in elderly patients with extreme caution and only if prescribed by the doctor.

What if I have taken an overdose of Malirid-DS Tablet

In case of an accidental overdose, seek immediate emergency medical attention or contact a poison control centre. Symptoms of an overdose may include severe stomach pain, vomiting, pale skin, blue-coloured lips or fingertips, and extreme fatigue.

Diet & Lifestyle Advise

  • Take with a fatty meal or milk: Taking your dose with food, especially meals containing a small amount of healthy fat or a glass of whole milk, can significantly reduce stomach irritation.
  • Stay well-hydrated: Drink plenty of water throughout the day to support your liver and kidneys as your body processes the medication and clears the infection.
  • Avoid alcohol: Do not consume alcohol while taking this medicine, as it can strain your liver and increase the risk of stomach upset.
  • Use mosquito protection: Continue to protect yourself from mosquito bites by using insect repellent, wearing long sleeves, and sleeping under a treated mosquito net to prevent new infections.
     
health query

Have a query?

How Soon It Starts Working

The time required for Malirid-DS Tablet to start to work: Malirid-DS Tablet ideally shows its action within 4 to 6 hours after administration. The time for which the effects of Malirid-DS Tablet last: The effect of Malirid-DS Tablet lasts for 24 hours.

What if you forget to take Malirid-DS Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you miss multiple doses.

Storage

• Store Malirid-DS Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Get tested for G6PD deficiency first: You must undergo a blood test for G6PD enzyme deficiency before taking Malirid-DS Tablet, as this medicine can cause life-threatening red blood cell breakdown in people with this condition.
  • Watch your urine colour: Pay close attention to the colour of your urine; if it turns dark brown or tea-coloured, stop taking the medicine and seek medical help immediately.
  • Do not take if pregnant: This medicine is unsafe during pregnancy. Use reliable birth control during treatment, and notify your doctor immediately if you suspect you are pregnant.
  • Complete the full course: Even if your symptoms disappear after a few days, you must finish the entire duration of the prescribed treatment to ensure the parasites in your liver are completely eradicated.
  • Inform all healthcare providers: Let any doctor, dentist, or pharmacist you visit know that you are currently taking or have recently finished a course of Malirid-DS Tablet.
     

Drug-Drug Interactions

verifiedApollotooltip

Malirid-DS Tablet may interact with certain medicines, increasing the risk of side effects or affecting how well your treatment works. Inform your doctor about all prescription medicines, over-the-counter products, and supplements you are taking, including:

  • Quinacrine: Taking Malirid-DS Tablet with quinacrine can increase the toxic effects of Malirid-DS Tablet, significantly raising the risk of severe side effects.
  • Bone marrow suppressing drugs: Combining this medicine with drugs that suppress bone marrow function can increase the risk of serious blood disorders
     

Drug-Drug Interactions

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How does the drug interact with Malirid-DS Tablet:
When Malirid-DS Tablet is taken with Dronedarone, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid-DS Tablet with Dronedarone is not advised generally as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Malirid-DS Tablet:
Coadministration of Malirid-DS Tablet with Cisapride can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid-DS Tablet with Cisapride is not advised generally as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Malirid-DS Tablet:
When Thioridazine and Malirid-DS Tablet are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid-DS Tablet with Thioridazine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
PrimaquineMesoridazine
Critical
How does the drug interact with Malirid-DS Tablet:
Using Malirid-DS Tablet with Mesoridazine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid-DS Tablet with Mesoridazine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Malirid-DS Tablet:
Taking Malirid-DS Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Malirid-DS Tablet is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
PrimaquineAuranofin
Critical
How does the drug interact with Malirid-DS Tablet:
Taking Malirid-DS Tablet with Auranofin may cause blood disorders and other severe side effects.

How to manage the interaction:
Taking Malirid-DS Tablet with Auranofin is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
PrimaquineAurothioglucose
Critical
How does the drug interact with Malirid-DS Tablet:
Taking Malirid-DS Tablet with Aurothioglucose may cause blood disorders and other severe side effects.

How to manage the interaction:
Taking Malirid-DS Tablet with Aurothioglucose is not advised generally as it can cause an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
PrimaquineHalofantrine
Critical
How does the drug interact with Malirid-DS Tablet:
Taking Malirid-DS Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Malirid-DS Tablet with Halofantrine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
PrimaquineSaquinavir
Critical
How does the drug interact with Malirid-DS Tablet:
When Malirid-DS Tablet is taken with Saquinavir, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid-DS Tablet with Saquinavir is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Malirid-DS Tablet:
When Pimozide and Malirid-DS Tablet are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid-DS Tablet with Pimozide is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

Although Malirid-DS Tablet can be taken with food to reduce stomach upset, certain dietary habits may influence how the medicine is tolerated.

  • Fatty foods and milk: While taking the medicine with food is highly recommended to protect your stomach, extremely greasy or excessively fatty meals might slightly alter how the drug is absorbed. Stick to a normal, balanced meal or a glass of milk.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- MALARIALS]

FAQs

Malirid-DS Tablet is used for the treatment of malaria.
No, as there may be a risk of hemolysis in patients with G6PD deficiency. Doctors consultation is mandatory.
Malirid-DS Tablet works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. In this way Malirid-DS Tablet used for the prevention of relapse of malaria caused by plasmodium vivax and Plasmodium ovale strains of the parasite.
Common side effects of Malirid-DS Tablet include rash, vomiting, headache, dizziness, hives, stomach pain, nausea, abdominal pain, itching, heartburn, gastrointestinal discomfort, upper abdominal pain.
No, do not stop taking Malirid-DS Tablet. It is recommended to take this medicine for the entire prescribed duration even when symptoms improve or resolve. Failure to do so might result in drug resistance and treating any subsequent infection with the same medicine would be very difficult.
No, Malirid-DS Tablet is not safe to use in heart problems. The use of this medicine may increase the risk of irregular heart rhythms. Therefore, it should be used with caution in patients with arrhythmias or any other heart diseases. Any symptoms of palpitations, difficulty in breathing should be reported to the doctor.
Malirid-DS Tablet is contraindicated in patients taking medications that may cause haemolysis or depress the myeloid elements of the bone marrow. It should not be taken by pregnant women and acutely ill patients with conditions like granulocytopenia (rheumatoid arthritis or lupus), or those who have recently taken quinacrine, as it may increase the risk of toxicity.
You should tell your doctor if you are taking cephalosporins such as cefaclor, cephalexin, cefuroxime, penicillin, cefdinir, or cefpodoxime, levodopa, medications to treat cancer, methyldopa or quinidine, or if you are taking or planning to take vitamins, nutritional supplements, and herbal products. Let the doctor know if you have or have ever had haemolytic anaemia (a condition with an abnormally low number of RBC), rheumatoid arthritis, lupus erythematosus (a disease that occurs when the body's tissues are attacked by antibodies from its immune system), methemoglobinemia (a condition with defective red blood cells that are unable to carry oxygen to the tissues in the body), nicotinamide adenine dinucleotide (NADH) deficiency (a genetic condition), glucose-6-phosphate dehydrogenase (G6PD) deficiency (a genetic condition) and if you are pregnant or breastfeeding.
Yes, Malirid-DS Tablet is safe if it is taken in the dose and duration prescribed by the doctor. Therefore, take Malirid-DS Tablet exactly prescribed by the doctor based on your medical condition.
If you have missed the dose, take it as soon as you remember and if it's already time for the next dose, skip the missed one and take the scheduled dose. Do not double the dose.
Swallow Malirid-DS Tablet as a whole with water; do not crush or chew it. Malirid-DS Tablet should be taken with food to decrease the risk of stomach upset.
Malirid-DS Tablet should be taken exactly as prescribed by the doctor, preferably with a meal to minimize stomach discomfort. For best results, take it at the same time every day.
No, Malirid-DS Tablet is not an antibiotic. It belongs to the group of medications called antimalarials used to treat and prevent malaria caused by the Plasmodium parasite. It is also used to prevent relapse of malaria caused by Plasmodium vivax and Plasmodium ovale.
Malirid-DS Tablet may impair kidney function in a few cases. Therefore, consult the doctor before taking Malirid-DS Tablet if you have any kidney problems.
Yes, Malirid-DS Tablet may cause drowsiness as a side effect. Avoid driving and operating machinery if you feel drowsiness and there is no evidence suggesting that Malirid-DS Tablet has any effect on blood pressure.
You need a blood test to check for G6PD deficiency, a common genetic trait. Taking Malirid-DS Tablet if you have this deficiency can cause your red blood cells to break down rapidly, leading to severe anaemia. Talk to your doctor to schedule this test before starting treatment.
It is highly recommended to take Malirid-DS Tablet with food or a glass of milk. Taking it on an empty stomach can cause significant nausea, vomiting, and stomach cramps. Talk to your doctor or pharmacist if you struggle with stomach upset.
If your urine turns dark brown or tea-coloured, stop taking the medicine and contact your doctor immediately. This is a primary sign of red blood cell breakdown, which requires prompt medical attention.
You must finish the full course to ensure all dormant malaria parasites in your liver are completely destroyed. Stopping early may leave sleeping parasites alive, which can wake up later and cause a relapse of malaria.
Malirid-DS Tablet is primarily used to prevent a relapse of certain types of malaria or to stop transmission, rather than as a primary preventive medicine for travellers. Talk to your doctor or pharmacist about the correct medications for malaria prevention before travelling.
Breastfeeding is generally not recommended unless both you and your infant have been tested and cleared of G6PD deficiency. The drug can pass into breast milk and harm a G6PD-deficient infant. Talk to your doctor to weigh the risks and benefits.
You should avoid alcohol while taking Malirid-DS Tablet. Alcohol can increase stomach irritation, worsen dizziness, and place extra stress on your liver during your recovery. Talk to your doctor if you have questions about alcohol use

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Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - MAL0008
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