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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Mecotop-Plus Injection 2 ml belongs to the class of vitamins used in the treatment of peripheral neuropathies and megaloblastic anaemia. This medicine contains methylcobalamin, which helps protect the nerves from damage and promotes blood cell production. Some of the common side effects include nausea, vomiting, diarrhoea, loss of appetite, and headache.

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Composition :

MECOBALAMIN-100MG

Manufacturer/Marketer :

Mediwin Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Mecotop-Plus Injection 2 ml

Mecotop-Plus Injection 2 ml is used to treat peripheral neuropathies and megaloblastic anaemia caused by vitamin B12 deficiency. Vitamin B12 is a vital dietary nutrient, and a deficiency of vitamin B12 can lead to peripheral neuropathy, megaloblastic anaemia, and many other serious conditions.

Mecotop-Plus Injection 2 ml contains Mecobalamin, a form of vitamin B12 that helps protect nerves from damage and promote blood cell production. It regulates body functions, such as cell multiplication, blood formation, and protein synthesis.

You may experience pain, itching, swelling or redness around the injection site, nausea, vomiting, diarrhoea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you have signs of an allergic reaction, such as swelling of the face, lips, or tongue or breathing problems.

To treat your condition effectually, continue taking Mecotop-Plus Injection 2 ml for as long as your doctor has prescribed. Please do not stop taking Mecotop-Plus Injection 2 ml without consulting your doctor. Do not take Mecotop-Plus Injection 2 ml if you are pregnant or breastfeeding unless prescribed by the doctor. Mecotop-Plus Injection 2 ml should be given to children as advised by your doctor.

Uses of Mecotop-Plus Injection 2 ml

Mecotop-Plus Injection 2 ml is a form of vitamin B12 used to treat and manage conditions related to vitamin B12 deficiency and nerve damage. The detailed uses of Mecotop-Plus Injection 2 ml are as follows:

  • Peripheral neuropathy: Mecotop-Plus Injection 2 ml promotes nerve healing and relieves numbness, tingling, and discomfort associated with nerve injury.
  • Megaloblastic anemia: Mecotop-Plus Injection 2 ml treats anemia caused by a deficiency of vitamin B12, improving red blood cell production.
  • Diabetic neuropathy: Mecotop-Plus Injection 2 ml reduces nerve-related symptoms in patients with diabetes by improving nerve function.
  • Vitamin B12 deficiency: Mecotop-Plus Injection 2 ml restores normal B12 levels in patients with low vitamin B12 due to poor diet, malabsorption, or other medical conditions.

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Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Mecotop-Plus Injection 2 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Medicinal Benefits

  • Mecotop-Plus Injection 2 ml treats and prevents vitamin B12 deficiency effectively.
  • Supports regeneration and protection of nerve cells, improving nerve function.
  • Helps relieve symptoms of neuropathy such as tingling, numbness, and nerve pain.
  • Promotes healthy red blood cell formation and prevents megaloblastic anaemia.
  • Boosts energy levels and reduces fatigue caused by vitamin B12 deficiency.
  • Supports brain and cognitive function, improving focus and memory.
  • Enhances metabolism of fats, proteins, and carbohydrates for better energy utilisation.
  • Aids in recovery from nerve injuries and strengthens the nervous system.
  • Provides faster, more direct absorption than oral supplements.

How Mecotop-Plus Injection 2 ml Works

Mecotop-Plus Injection 2 ml contains Mecobalamin, a form of vitamin B12 that helps protect the nerves from damage and also helps to promote blood cell production. It regulates body functions, such as cell multiplication, blood formation, and protein synthesis.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Mecotop-plus Inj 2ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the six steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Mecotop-Plus Injection 2 ml

The overdose of Mecotop-Plus Injection 2 ml is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Mecotop-Plus Injection 2 ml, please inform your doctor immediately.

Drug Warnings

  • Do not consume Mecotop-Plus Injection 2 ml if you are allergic to any ingredients in Mecotop-Plus Injection 2 ml.
  • To treat your condition effectually, continue taking Mecotop-Plus Injection 2 ml for as long as your doctor has prescribed.
  • Please do not stop taking Mecotop-Plus Injection 2 ml without consulting your doctor.
  • Do not take Mecotop-Plus Injection 2 ml if you are pregnant or breastfeeding unless prescribed by the doctor.
  • Inform your doctor if you have low potassium levels in the blood, iron or folic acid deficiency, or if you have had optic nerve damage.
  • Keep your doctor informed about your health condition and any medicines you are taking to help rule out any side effects.

Drug-Drug Interactions

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NicotinamideMipomersen
Severe

Drug-Drug Interactions

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How does the drug interact with Mecotop-plus Inj 2ml:
Taking Mecotop-plus Inj 2ml with Ketoconazole can increase the risk or severity of liver injury.

How to manage the interaction:
Taking Mecotop-plus Inj 2ml with Ketoconazole together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NicotinamideMipomersen
Severe
How does the drug interact with Mecotop-plus Inj 2ml:
Coadministration of Mecotop-plus Inj 2ml and Mipomersen can increase the risk of liver damage.

How to manage the interaction:
Co-administration of Mecotop-plus Inj 2ml with Mipomersen can result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on any signs of liver problems. If you notice any symptoms like fever, joint pain, or loss of appetite, it's best to call a doctor right away. They can help determine if there is any liver damage and provide the necessary treatment. Do not stop using any medications without a doctor's advice.
How does the drug interact with Mecotop-plus Inj 2ml:
Coadministration of Mecotop-plus Inj 2ml with Rosuvastatin may increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage which can be fatal.

How to manage the interaction:
Taking Mecotop-plus Inj 2ml with Rosuvastatin together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like unexplained muscle pain, muscle stiffness or tenderness, fever, dark-coloured urine, or weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Mecotop-plus Inj 2ml:
Coadministration of Mecotop-plus Inj 2ml with Lovastatin can increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage.

How to manage the interaction:
Taking high-dose Mecotop-plus Inj 2ml with Lovastatin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mecotop-plus Inj 2ml:
Coadministration of Mecotop-plus Inj 2ml with leflunomide can increase the risk or severity of liver problems.

How to manage the interaction:
Although there is an interaction between Mecotop-plus Inj 2ml and leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mecotop-plus Inj 2ml:
Coadministration of Mecotop-plus Inj 2ml and Teriflunomide can increase the risk of liver damage.

How to manage the interaction:
Taking Mecotop-plus Inj 2ml with Teriflunomide together can result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on any signs of liver problems. If you notice any symptoms like fever, joint pain, or loss of appetite, it's best to call a doctor right away. They can help determine if there is any liver damage or bleeding and provide the necessary treatment. Do not stop using any medications without a doctor's advice.
How does the drug interact with Mecotop-plus Inj 2ml:
Coadministration of Mecotop-plus Inj 2ml with Atorvastatin can increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage.

How to manage the interaction:
Taking Mecotop-plus Inj 2ml with Atorvastatin together is used with caution as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mecotop-plus Inj 2ml:
Co-administration of Mecotop-plus Inj 2ml with Pitavastatin can increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle).

How to manage the interaction:
Taking Mecotop-plus Inj 2ml with Pitavastatin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Mecotop-plus Inj 2ml:
Coadministration of Mecotop-plus Inj 2ml with Simvastatin can increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage.

How to manage the interaction:
Taking Mecotop-plus Inj 2ml with Simvastatin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NicotinamideLomitapide
Severe
How does the drug interact with Mecotop-plus Inj 2ml:
Coadministration of Mecotop-plus Inj 2ml and Lomitapide can increase the risk of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Mecotop-plus Inj 2ml and Lomitapide, but it can be taken if prescribed by a doctor. It is important to keep an eye out for any signs of liver damage. If you notice any symptoms like fever, joint pain, or loss of appetite, it's a good idea to contact a doctor right away. They can help determine if there is any liver damage and provide appropriate treatment. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take fresh fruits and vegetables into your diet.
  • Eat fortified cereals in your diet.
  • Drink milk, make cheese, and yoghurt in your diet.
  • Take eggs, meat, and fish into your diet.
  • Avoid oily and canned foods.
  • Avoid tea and coffee.
  • Quit smoking and avoid drinking alcohol.

Habit Forming

No

Therapeutic Class

VITAMINS

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Alcohol

Caution

Alcohol does not affect the results of Mecotop-Plus Injection 2 ml. However, excessive alcohol consumption can result in folate-deficient anaemia.

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Pregnancy

Consult your doctor

If you are pregnant, inform your doctor before taking this medicine. Your doctor may prescribe Mecotop-Plus Injection 2 ml if the benefits outweigh the risks.

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Breast Feeding

Safe if prescribed

Mecotop-Plus Injection 2 ml is considered safe for use during breastfeeding. However, if you are breastfeeding, inform your doctor before taking Mecotop-Plus Injection 2 ml.

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Driving

Safe if prescribed

Mecotop-Plus Injection 2 ml does not affect the ability to drive or operate.

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Liver

Caution

Mecotop-Plus Injection 2 ml should be administered with caution in patients with severe liver disease. If you have liver problems, inform your doctor before taking Mecotop-Plus Injection 2 ml. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Mecotop-Plus Injection 2 ml should be administered with caution in patients with kidney disease. If you have kidney problems, inform your doctor before taking Mecotop-Plus Injection 2 ml. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Safe if prescribed

Mecotop-Plus Injection 2 ml can be prescribed for children under 12 years old, but your doctor will make dose adjustments.

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Heart

Caution

Mecotop-Plus Injection 2 ml should be administered with caution in patients with heart problems. Please inform your doctor before receiving Mecotop-Plus Injection 2 ml.

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Geriatrics

Consult your doctor

Mecotop-Plus Injection 2 ml can be administered to elderly patients, but dose adjustment may be needed based on health conditions.

FAQs

Mecotop-Plus Injection 2 ml belongs to the Vitamins class, primarily used to treat peripheral neuropathies and megaloblastic anaemia caused by vitamin B12 deficiency. Vitamin B12 is a vital dietary nutrient, and a deficiency of vitamin B12 can lead to peripheral neuropathy, megaloblastic anaemia, and many other severe conditions.

Mecobalamin is a synthetic form of vitamin B12. It works by increasing vitamin B12 levels in your body, helping treat anaemia and nerve problems.

Pain, swelling, or itchy skin at the injection site; these symptoms are often mild and should last only a few hours. If the discomfort is affecting you, you might seek a healthcare expert for a mild pain reliever.

When your vitamin B12 (Mecobalamin) blood levels return to normal, you may be able to discontinue taking Mecobalamin. However, if your diet lacks vitamin B12 or you cannot absorb enough vitamin B12 from food, you may need to take it for the rest of your life.

Vitamin B12 deficiency occurs when you don't have enough Methylcobalamin or Mecobalamin levels in the body. You can include natural sources of Vitamin B12, such as eggs, beef, liver, chicken, trout, salmon, tuna, fish, clams, fortified breakfast cereal, low-fat milk, yoghurt, and cheese, in your diet to treat the deficiency. If you still have low B12 levels, please consult your doctor.

Diarrhoea might be a side-effect of Mecotop-Plus Injection 2 ml. Drink lots of fluids and eat food rich in fibre. If you find blood in your stools (tarry stools) or if you experience excess diarrhoea, consult your doctor.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Mecotop-Plus Injection 2 ml belongs to the class of vitamins used to treat peripheral neuropathies and megaloblastic anaemia. This medicine contains Mecobalamin, a form of vitamin B12, which helps protect the nerves from damage and promotes blood cell production.

You may need more vitamin B12 in your diet due to various reasons. Vitamin B12 is primarily found in animal-based foods, so vegetarians and vegans may need help to get enough. Digestive issues, ageing, gastrointestinal surgery, and certain medications can also lead to malabsorption. Additionally, inadequate dietary intake or increased requirements due to pregnancy, breastfeeding, or medical conditions can contribute to vitamin B12 deficiency. If you're concerned, consult a healthcare professional or registered dietitian to determine the best approach for your individual needs.

If you have a vitamin B12 deficiency, you may experience a range of symptoms, including fatigue and weakness, shortness of breath, pale skin, headaches, dizziness, numbness or tingling in hands and feet, digestive issues like diarrhoea or constipation, mood changes like depression or anxiety, and memory loss or cognitive impairment. If left untreated, vitamin B12 deficiency can lead to more severe health problems, such as anaemia, nerve damage (peripheral neuropathy), increased risk of cardiovascular disease, increased risk of neurological disorders like multiple sclerosis, and increased risk of birth defects if pregnant. It is essential to consult a healthcare professional for a proper diagnosis and treatment plan to manage the deficiency and related symptoms.

Mecotop-Plus Injection 2 ml is a safe and effective treatment option when used properly and under medical supervision. It has a well-established safety profile, and most people tolerate it well. While some mild side effects may occur, they are usually temporary and resolve on their own. Serious side effects are rare; your healthcare professional will closely monitor you to minimize potential risks. With proper administration and dosing, Mecobalamin Injection can help effectively manage vitamin B12 deficiency and related conditions.

A healthcare professional should give Mecotop-Plus Injection 2 ml in a clinical setting. It's usually injected into a muscle or vein, typically in the buttock, thigh, or arm.

When giving a Mecotop-Plus Injection 2 ml, following some simple steps to ensure safe and effective use is essential. Use clean equipment to avoid infection, and always check the injection site for any signs of problems. Use a new needle and syringe each time, and be careful to avoid injecting into blood vessels or nerves. Also, remember to rotate the injection site to minimise discomfort. Finally, watch for any signs of an allergic reaction. By following these easy steps, you can help ensure the injection is used safely and effectively.

Mecotop-Plus Injection 2 ml contains Mecobalamin, a form of vitamin B12.

Mecotop-Plus Injection 2 ml replenishes vitamin B12 in the body, supporting the production of red blood cells, nerve cells, and energy. This helps restore levels and promote overall health and well-being.

The doctor will assess your medical condition and decide whether an oral supplement or a parenteral (injectable) form of Mecobalamin, such as Mecotop-Plus Injection 2 ml, best suits you. They will consider factors such as the severity of your deficiency, your ability to absorb nutrients, and any underlying health conditions.

Common side effects of Mecotop-Plus Injection 2 ml may include pain, itching, swelling or redness around the injection site, nausea, vomiting, diarrhoea, and headache. Most of these side effects do not require medical attention and resolve gradually over time.

Before starting any new medication, including Mecotop-Plus Injection 2 ml, it's essential to inform your doctor about your medical history, allergies, and current medications. This includes sharing information about liver or kidney disease, pregnancy or breastfeeding, and other health conditions. This helps your doctor determine if the medication is safe for you to use and monitor you for any potential side effects.

To ensure safe and effective treatment, you must tell your doctor about all medications you're currently taking, including over-the-counter drugs and supplements. This is because medications can interact with one another, affecting their absorption or effectiveness. Your doctor may need to adjust the dosage or monitoring schedule to avoid potential interactions. Sharing your full medication list can help your doctor provide the best possible care.

Mecotop-Plus Injection 2 ml should be stored in a cool, dry place away from sunlight. Keep out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

No-2, Vita Enclave, Dhoolkot, Ambala, Haryana, 1330001, India
Other Info - MEC0668

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