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  3. Meflin 500mg Tablet

Meflin 500mg Tablet, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Meflin 500mg Tablet is used to provide relief from mild to moderate pain and inflammation associated with muscular, rheumatic, and arthritic disorders, headache, trauma, dental pain, and pain after surgery or childbirth. Additionally, it is used to relieve period pain and premenstrual syndrome symptoms (PMS) and manage excessively heavy periods. It contains Mefenamic acid, which works by blocking the effect of chemical messengers that cause pain and inflammation. In some cases, you may experience certain common side effects such as abdominal pain, nausea, vomiting, diarrhoea, heartburn and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

MEFENAMIC ACID-500MG

Manufacturer/Marketer :

Lincoln Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Meflin 500mg Tablet

Meflin 500mg Tablet is used to provide relief from mild to moderate pain and inflammation associated with muscular, rheumatic, and arthritic disorders, headache, trauma, dental pain, and pain after surgery or childbirth. Additionally, Meflin 500mg Tablet is used to relieve period pain and premenstrual syndrome symptoms (PMS) and manage excessively heavy periods.

Meflin 500mg Tablet contains 'mefenamic acid', which works by blocking the effect of chemical messengers that cause pain and inflammation. Thereby relieving pain and inflammation.

In some cases, you may experience certain common side effects such as abdominal pain, nausea, vomiting, diarrhoea, heartburn and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Meflin 500mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol with Meflin 500mg Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and any medications you are taking to help rule out any potential side effects.

Uses of Meflin 500mg Tablet

Meflin 500mg Tablet is used to relieve pain and inflammation in various conditions. The detailed uses of Meflin 500mg Tablet are as follows:
• Treatment of menstrual pain (dysmenorrhea): Provides effective relief from lower abdominal cramps and discomfort during menstruation.
• Management of mild to moderate pain: Used to treat headaches, joint pain, and muscular aches.
• Relief from arthritis-related pain: Meflin 500mg Tablet helps manage pain and inflammation in conditions like osteoarthritis and rheumatoid arthritis.
• Fever reduction: Reduces body temperature in mild to moderate fevers.
• Post-operative pain management: Reduces pain and inflammation after surgical operations or childbirth.
• Support in inflammatory conditions: Reduces swelling, redness, and discomfort in various musculoskeletal disorders.

Directions for Use

  • Meflin 500mg Tablet can be taken with food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Tablet/capsule: Swallow it as a whole with a glass of water.
  • Dispersible tablet: Dissolve the tablet in a glass of water and consume it immediately.
  • Do not break, chew, or crush it.

Medicinal Benefits

Meflin 500mg Tablet belongs to a group of medicines called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to provide relief from mild to moderate pain and inflammation associated with musculoskeletal, rheumatic, arthritic disorders, headaches, trauma, dental pain, and pain after surgery or childbirth. Additionally, Meflin 500mg Tablet is used to relieve period pain, symptoms of premenstrual syndrome (PMS), and management of excessively heavy periods. Meflin 500mg Tablet works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes, which make another chemical, prostaglandins. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

How Meflin 500mg Tablet Works

Meflin 500mg Tablet contains 'mefenamic acid', which works by blocking the effect of chemical messengers that cause pain and inflammation. Thereby relieving pain and inflammation.

Storage

Store in a cool and dry place away from sunlight
Side effects of Meflin 500mg Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Meflin 500mg Tablet

Do not take more than the prescribed dose of Meflin 500mg Tablet as it may cause an overdose. The symptoms of overdose include nausea, vomiting, extreme tiredness, stomach pain, vomit that is bloody or looks like coffee grounds, black/tarry/bloody stools, slowed breathing or coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Meflin 500mg Tablet if you are allergic to any of its components, if you have severe heart, kidney or liver failure, have suffered bleeding problems such as bleeding from the stomach or bowels while taking any pain killers or have peptic ulcers or inflammatory bowel disease. Inform your doctor if you have high blood pressure, heart problems, high cholesterol, dehydration, asthma, liver and kidney problems. Consult your doctor if you are pregnant or breastfeeding. Meflin 500mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Stop taking Meflin 500mg Tablet and consult your doctor immediately if you experience stomach pain or any signs of intestinal or stomach bleeding, such as blood in your stools.

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
Mefenamic acidKetorolac
Critical

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
How does the drug interact with Meflin 500mg Tablet:
Co-administration of Meflin 500mg Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Meflin 500mg Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Meflin 500mg Tablet:
Coadministration of Meflin 500mg Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Meflin 500mg Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidLeflunomide
Severe
How does the drug interact with Meflin 500mg Tablet:
Coadministration of Meflin 500mg Tablet with Leflunomide can increase the risk or severity of liver disease.

How to manage the interaction:
Taking Meflin 500mg Tablet with Leflunomide together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidSirolimus
Severe
How does the drug interact with Meflin 500mg Tablet:
Co-administration of Meflin 500mg Tablet with Sirolimus can increase the risk or severity of kidney disorders.

How to manage the interaction:
Taking Meflin 500mg Tablet with Sirolimus together can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidIndometacin
Severe
How does the drug interact with Meflin 500mg Tablet:
The combined use of Indometacin and Meflin 500mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Indometacin with Meflin 500mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Mefenamic acidRivaroxaban
Severe
How does the drug interact with Meflin 500mg Tablet:
Coadministration of Meflin 500mg Tablet with Rivaroxaban can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Meflin 500mg Tablet with Rivaroxaban together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidTenofovir disoproxil
Severe
How does the drug interact with Meflin 500mg Tablet:
Coadministration of Meflin 500mg Tablet with Tenofovir disoproxil can show additive effect and increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Meflin 500mg Tablet with Tenofovir Disoproxil together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, red or black tarry stools, vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidDalteparin
Severe
How does the drug interact with Meflin 500mg Tablet:
Combining Meflin 500mg Tablet with Dalteparin can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Dalteparin and Meflin 500mg Tablet together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any signs like bleeding, bruising, swelling, vomiting, headache, dizziness, weakness, or blood in your urine or stool, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Mefenamic acidLomitapide
Severe
How does the drug interact with Meflin 500mg Tablet:
Coadministration of Meflin 500mg Tablet with Lomitapide can cause liver damage.

How to manage the interaction:
Co-administration of Meflin 500mg Tablet with Lomitapide can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, bleeding, pain, dark urine, or liver damage. Do not stop using any medications without a doctor's advice.
Mefenamic acidMethotrexate
Severe
How does the drug interact with Meflin 500mg Tablet:
Coadministration of Meflin 500mg Tablet with Methotrexate may increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between Meflin 500mg Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.

Drug-Food Interactions

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MEFENAMIC ACID-500MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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MEFENAMIC ACID-500MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking Meflin 500mg Tablet with caffeine-containing foods or drinks can show an interaction. Taking Meflin 500mg Tablet with caffeine-containing foods or drinks can reduce the effectiveness of Meflin 500mg Tablet. Avoid or limit your caffeine consumption while taking Meflin 500mg Tablet dose. Do not stop using any medications without talking to a doctor.

Diet & Lifestyle Advise

  • Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat pain. Apply an ice pack or hot pack on the muscle for 15-20 minutes.
  • Stay hydrated by drinking plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Meflin 500mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Meflin 500mg Tablet as it may increase drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Meflin 500mg Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Meflin 500mg Tablet may pass into breastmilk. Consult your doctor if you are breastfeeding.

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Driving

Caution

Meflin 500mg Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Please consult your doctor. Your doctor will recommend it based on your child's condition.

Have a query?

FAQs

Meflin 500mg Tablet is used to provide relief from mild to moderate pain and inflammation associated with muscular, rheumatic, and arthritic disorders, headache, trauma, dental pain, and pain after surgery or childbirth. Additionally, it is used to relieve period pain and premenstrual syndrome symptoms (PMS) and manage excessively heavy periods.

Meflin 500mg Tablet works by blocking the chemical messengers that are responsible for pain and inflammation. Thereby, Meflin 500mg Tablet provides relief from pain and inflammation.

Meflin 500mg Tablet is generally prescribed for short-term use. Do not take Meflin 500mg Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding.

Meflin 500mg Tablet is used to relieve menstrual (period) pain, symptoms of premenstrual syndrome (PMS), and management of excessively heavy periods. Take only as prescribed by the doctor.

Avoid taking Meflin 500mg Tablet if you have stomach ulcers. Meflin 500mg Tablet might increase the risk of stomach ulcers, perforation of the stomach and intestinal bleeding with higher doses.

Diarrhoea might be a side-effect of Meflin 500mg Tablet. Drink plenty of fluids and eat food rich in fibre. Consult your doctor if you experience excessive diarrhoea or if you find blood in stools.

It is considered harmful for patients with severe kidney problems and those experiencing active intravascular clotting, which obstructs blood flow due to blood clots.

Store Meflin 500mg Tablet at room temperature, away from sunlight. Keep the Meflin 500mg Tablet out of reach of children.

No, Meflin 500mg Tablet doesn’t act as a contraceptive; it is used to relieve mild to moderate pain and inflammation.

Meflin 500mg Tablet should be taken only as it is prescribed by the doctor. Do not self-medicate and do not recommend Meflin 500mg Tablet to others with the same condition.

Meflin 500mg Tablet is not recommended during pregnancy unless advised by the doctor. Therefore, if you are pregnant or planning to become pregnant, please consult a doctor.

If the dose of Meflin 500mg Tablet is missed, take the missed dose as soon as you remember. If it is time for the next dose, skip the missed dose and continue taking the regular dose. Avoid taking a double dose to make up for the missed one.

Meflin 500mg Tablet is used for a short time, not more than 3-5 days of your menstrual cycle. However, the duration for your use will be advised by the doctor. Do not self-medicate.

Country of origin

India
Other Info - ME47428

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 11, 2025 | 8:29 AM IST

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Reference

  1. https://www.hpra.ie/img/uploaded/swedocuments/eec4b0f8-a82a-4ba9-8e04-d411ee4d7b95.pdf
  2. https://meftal.com/assets/MEFTAL-250-DT.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/015034s040lbl.pdf
  4. https://medlineplus.gov/druginfo/meds/a681028.html
  5. https://www.drugs.com/mtm/mefenamic-acid.html
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