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Megoal Trio 20mg/10mg/12.5mg Tablet

Megoal Trio 20mg/10mg/12.5mg Tablet is used to treat hypertension (high blood pressure). It effectively lowers elevated blood pressure, improves overall blood circulation, and supports better heart function. By controlling blood pressure, it reduces the risk of serious complications such as heart attack, stroke, and other cardiovascular problems, thereby promoting long-term heart health.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHLORTHALIDONE-12.5MG+CILNIDIPINE-10MG+OLMESARTAN MEDOXOMIL-20MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Megoal Trio 20mg/10mg/12.5mg Tablet

Megoal Trio 20mg/10mg/12.5mg Tablet belongs to the class of medicines called hypertensives, primarily used to treat hypertension (high blood pressure). Hypertension or high blood pressure is a chronic condition in which the force of blood against the artery wall is high. 

Megoal Trio 20mg/10mg/12.5mg Tablet contains Olmesartan medoxomil, Cilnidipine, and Chlorthalidone, which work by relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently.

Take Megoal Trio 20mg/10mg/12.5mg Tablet as advised by the doctor. You may experience side effects like headache, nausea, swelling of legs/hands, or dizziness. Most of the side effects of Megoal Trio 20mg/10mg/12.5mg Tablet do not require medical attention and resolve gradually over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Megoal Trio 20mg/10mg/12.5mg Tablet if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to prevent any interactions.

Uses of Megoal Trio 20mg/10mg/12.5mg Tablet

Megoal Trio 20mg/10mg/12.5mg Tablet is used in the treatment of Hypertension (high blood pressure). The detailed uses of Megoal Trio 20mg/10mg/12.5mg Tablet are as follows:

  • Hypertension (High Blood Pressure): Megoal Trio 20mg/10mg/12.5mg Tablet effectively lowers blood pressure by relaxing blood vessels and reducing fluid retention.

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Directions for Use

  • Megoal Trio 20mg/10mg/12.5mg Tablet should be taken with food to avoid stomach upset. Taking it with food also allows for slower absorption and reduces the risk of a sudden drop in blood pressure.
  • Follow your doctor's instructions on the dosage and timing of this medication. It is preferable to take it at the same time each day for better results.
  • Swallow Megoal Trio 20mg/10mg/12.5mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

  • Helps effectively lower high blood pressure by combining three complementary medicines.
  • Relaxes and widens blood vessels, allowing smoother blood flow and easier heart function.
  • Reduces the workload on the heart, improving overall cardiac efficiency.
  • Removes excess fluid and salts from the body, helping maintain healthy blood pressure levels.
  • Lowers the risk of serious complications such as heart attack and stroke.
  • Provides cardiovascular protection by reducing strain on the heart and blood vessels.
  • Helps protect the kidneys from damage caused by long-term high blood pressure.
  • Supports long-term blood pressure control and overall heart-kidney health.

How Megoal Trio 20mg/10mg/12.5mg Tablet Works

Megoal Trio 20mg/10mg/12.5mg Tablet is a combination of three medicines, namely: Olmesartan medoxomil, Cilnidipine, and Chlorthalidone. • Olmesartan medoxomil works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. • Cilnidipine blocks the activities of the calcium channels present in the blood vessels of the heart. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. • Chlorthalidone (diuretic) removes extra water and certain electrolytes from the body and efficiently reduces blood pressure. Thus, it helps to lower high blood pressure, reducing the chances of a heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Megoal Trio 20mg/10mg/12.5mg Tablet

An overdose of Megoal Trio 20mg/10mg/12.5mg Tablet may cause unpleasant effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Megoal Trio 20mg/10mg/12.5mg Tablet should not be given to people who are allergic to any of its components, or have low blood pressure (less than 90 mm of Hg).
  • Inform your doctor if you have had a heart attack, kidney disease, liver disease, are pregnant, planning to get pregnant, or breastfeeding.
  • Grapefruit juice and St. John's wort plant should not be consumed when taking Megoal Trio 20mg/10mg/12.5mg Tablet as it is contraindicated.
  • Let your doctor know if you are taking any other medicines.

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
chlorthalidoneCisapride
Critical

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
How does the drug interact with Megoal Trio 20mg/10mg/12.5mg Tablet:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Megoal Trio 20mg/10mg/12.5mg Tablet with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
chlorthalidoneCisapride
Critical
How does the drug interact with Megoal Trio 20mg/10mg/12.5mg Tablet:
Co-administration of Megoal Trio 20mg/10mg/12.5mg Tablet and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Megoal Trio 20mg/10mg/12.5mg Tablet with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
Olmesartan medoxomilCaptopril
Severe
How does the drug interact with Megoal Trio 20mg/10mg/12.5mg Tablet:
When Megoal Trio 20mg/10mg/12.5mg Tablet is taken with captopril, it may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Megoal Trio 20mg/10mg/12.5mg Tablet with captopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilPerindopril
Severe
How does the drug interact with Megoal Trio 20mg/10mg/12.5mg Tablet:
Coadministration of Megoal Trio 20mg/10mg/12.5mg Tablet with perindopril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Megoal Trio 20mg/10mg/12.5mg Tablet together with perindopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilPotassium chloride
Severe
How does the drug interact with Megoal Trio 20mg/10mg/12.5mg Tablet:
Using Megoal Trio 20mg/10mg/12.5mg Tablet with Potassium chloride may increase Potassium levels in the blood.

How to manage the interaction:
Although taking Megoal Trio 20mg/10mg/12.5mg Tablet together with Potassium chloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilTriamterene
Severe
How does the drug interact with Megoal Trio 20mg/10mg/12.5mg Tablet:
Taking Megoal Trio 20mg/10mg/12.5mg Tablet with triamterene may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Megoal Trio 20mg/10mg/12.5mg Tablet with triamterene may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilAmiloride
Severe
How does the drug interact with Megoal Trio 20mg/10mg/12.5mg Tablet:
Taking Amiloride with Megoal Trio 20mg/10mg/12.5mg Tablet can elevate potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking amiloride with Megoal Trio 20mg/10mg/12.5mg Tablet may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilRamipril
Severe
How does the drug interact with Megoal Trio 20mg/10mg/12.5mg Tablet:
Taking ramipril together with olmesartan may increase the risk of side effects (blood pressure, kidney function impairment, and a condition called Hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking Megoal Trio 20mg/10mg/12.5mg Tablet with ramipril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilTrimethoprim
Severe
How does the drug interact with Megoal Trio 20mg/10mg/12.5mg Tablet:
Taking Megoal Trio 20mg/10mg/12.5mg Tablet with trimethoprim may increase potassium levels in the blood.

How to manage the interaction:
Although taking Megoal Trio 20mg/10mg/12.5mg Tablet with trimethoprim may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilLithium
Severe
How does the drug interact with Megoal Trio 20mg/10mg/12.5mg Tablet:
Taking lithium with Megoal Trio 20mg/10mg/12.5mg Tablet may significantly increase the blood levels of lithium .

How to manage the interaction:
Although taking Megoal Trio 20mg/10mg/12.5mg Tablet alongside lithium can lead to interaction, they can be taken if prescribed by a doctor. However, if you develop sleepiness, dizziness, confusion, loose stools, vomiting, muscular weakness, muscle incoordination, a shaking sensation, blurred vision, ringing in the ears, excessive thirst, and/or increased urination, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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CHLORTHALIDONE-12.5MG+CILNIDIPINE-10MG+OLMESARTAN MEDOXOMIL-20MGPotassium rich foods
Moderate

Drug-Food Interactions

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CHLORTHALIDONE-12.5MG+CILNIDIPINE-10MG+OLMESARTAN MEDOXOMIL-20MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
When Megoal Trio 20mg/10mg/12.5mg Tablet is taken along with potassium-containing salt substitutes or over-the-counter potassium supplements it may lead to high potassium levels in blood. Avoid taking potassium-containing salt substitutes or over-the-counter potassium supplements with Megoal Trio 20mg/10mg/12.5mg Tablet as this can lead to high potassium levels in the blood. However, consult a doctor if you experience weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs.

Diet & Lifestyle Advise

Healthy Weight Management:

  • Keep your weight under control by maintaining a BMI between 19.5 and 24.9.
  • Achieving a healthy weight helps reduce strain on the heart and blood vessels.

Physical Activity:

  • Engage in regular physical activity for at least 150 minutes per week.
  • Aim for about 30 minutes of exercise on most days to help lower blood pressure.
  • Regular exercise can reduce raised blood pressure by around 5 mm Hg.

Healthy Diet:

  • Choose a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.
  • Include balanced meals that support heart health and blood pressure control.

Salt Intake:

  • Control Limit sodium (table salt) intake to no more than 2300 mg per day.
  • Reducing sodium to below 1500 mg per day is ideal for most adults.

Stress Management:

  • Avoid chronic stress, as it can increase blood pressure levels.
  • Spend quality time with loved ones to promote emotional well-being.
  • Practice mindfulness techniques to help manage daily stress.

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Megoal Trio 20mg/10mg/12.5mg Tablet can lower your blood pressure, causing dizziness and drowsiness. It can also cause orthostatic hypotension (a sudden fall in blood pressure while standing). So try to avoid taking Megoal Trio 20mg/10mg/12.5mg Tablet with alcoholic beverages.

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Pregnancy

Unsafe

Megoal Trio 20mg/10mg/12.5mg Tablet is pregnancy risk category D medicine which may cause harm to the fetus or unborn baby. So, when pregnancy is detected, discontinue Megoal Trio 20mg/10mg/12.5mg Tablet as soon as possible and consult the doctor.

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Breast Feeding

Caution

Megoal Trio 20mg/10mg/12.5mg Tablet passes into the breast milk, but its effect on the baby is not clear. Therefore, it is advisable to contact the doctor before intake of Megoal Trio 20mg/10mg/12.5mg Tablet.

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Driving

Unsafe

Megoal Trio 20mg/10mg/12.5mg Tablet may cause side effects, which could affect your ability to drive. Taking Megoal Trio 20mg/10mg/12.5mg Tablet may lower your blood pressure.

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Liver

Caution

Megoal Trio 20mg/10mg/12.5mg Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Not recommended in patients with chronic kidney disease (severe renal impairment). Safety and effectiveness in patients with severe renal impairment have not been established.

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Children

Unsafe

Megoal Trio 20mg/10mg/12.5mg Tablet is not recommended in children. The safety and efficacy of Megoal Trio 20mg/10mg/12.5mg Tablet in children have not yet been established.

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Heart

Caution

Megoal Trio 20mg/10mg/12.5mg Tablet is often prescribed to patients with heart problems to treat hypertension. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.

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Geriatrics

Caution

Megoal Trio 20mg/10mg/12.5mg Tablet should be taken with caution in geriatric patients. Please inform your doctor before using Megoal Trio 20mg/10mg/12.5mg Tablet.

FAQs

Megoal Trio 20mg/10mg/12.5mg Tablet is used to treat high blood pressure. It works by relaxing blood vessels, reducing the heart's workload and making the heart more efficient at pumping blood throughout the body. It also removes extra water and certain electrolytes from the body and efficiently reduces blood pressure.

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have a persistent headache, please consult your doctor immediately.

Megoal Trio 20mg/10mg/12.5mg Tablet is a combination of three medicines, namely Olmesartan medoxomil, Cilnidipine, and Chlorthalidone, which help lower raised blood pressure effectively. Olmesartan medoxomil works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine blocks the activities of the calcium channels present in the heart's blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Chlorthalidone (diuretic) removes extra water and certain electrolytes from the body and efficiently reduces blood pressure. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Yes, Megoal Trio 20mg/10mg/12.5mg Tablet is contraindicated in people with known allergy to any of this medicine's components. It should be avoided in people with severe kidney or liver impairment and people with anuria (reduction or absence of urine). It should also be avoided in women who are in the second and third trimesters of their pregnancy.

Yes, Megoal Trio 20mg/10mg/12.5mg Tablet can cause dry mouth. Therefore, it is always advised to increase fluid intake while taking Megoal Trio 20mg/10mg/12.5mg Tablet. If you still feel excessively thirsty, please consult your doctor and follow their advice for the best results.

Yes, Megoal Trio 20mg/10mg/12.5mg Tablet is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists, consult your doctor and do what is advised.

Yes, Megoal Trio 20mg/10mg/12.5mg Tablet can cause an upset stomach. So, it is preferred to take Megoal Trio 20mg/10mg/12.5mg Tablet with food to avoid it.

High blood pressure during pregnancy may cause eclampsia, which can be harmful to both the baby and the mother. Therefore, during pregnancy, you should have regular blood pressure monitoring.

Megoal Trio 20mg/10mg/12.5mg Tablet and Cilacar 10 are medications used to treat high blood pressure (hypertension). Still, they differ in their composition and mechanism of action. Megoal Trio 20mg/10mg/12.5mg Tablet contains Olmesartan medoxomil, Cilnidipine, and chlorthalidone. Whereas Cilacar 10 contains Cilnidipine.

Megoal Trio 20mg/10mg/12.5mg Tablet and Benlong 4 mg are medications used to treat high blood pressure (hypertension). Still, they differ in their active ingredients and mechanism of action. Megoal Trio 20mg/10mg/12.5mg Tablet contains Olmesartan medoxomil, Cilnidipine, and chlorthalidone. Whereas Benlong 4 mg contains Benidipine.

Megoal Trio 20mg/10mg/12.5mg Tablet and Telma 40 are medications for treating high blood pressure (hypertension). Still, they differ in their composition and mechanism of action. Megoal Trio 20mg/10mg/12.5mg Tablet contains Olmesartan medoxomil, Cilnidipine, and chlorthalidone. Whereas Telma 40 contains Telmisartan.

Megoal Trio 20mg/10mg/12.5mg Tablet and Ciplar tablet differ in their composition and mechanism of action. Megoal Trio 20mg/10mg/12.5mg Tablet contains Olmesartan medoxomil, Cilnidipine, and chlorthalidone, while the Ciplar tablet contains Propranolol.

Common side effects of Megoal Trio 20mg/10mg/12.5mg Tablet may include headache, nausea, peripheral oedema (swelling of legs/hands), or dizziness in some cases. Most of these side effects of Megoal Trio 20mg/10mg/12.5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Megoal Trio 20mg/10mg/12.5mg Tablet can start showing its effect within one hour of its oral intake. However, it may take a few days to show its full effect, and this may vary from person to person.

Yes, Megoal Trio 20mg/10mg/12.5mg Tablet can generally be taken on an empty stomach. However, it's always best to follow your doctor's instructions or as mentioned on the medication label.

No, you should not take Megoal Trio 20mg/10mg/12.5mg Tablet or any other prescription medication on your own. Megoal Trio 20mg/10mg/12.5mg Tablet is a prescription medication used to treat high blood pressure. Consult with a healthcare professional before starting any new medication, including Megoal Trio 20mg/10mg/12.5mg Tablet, is essential. They can diagnose your condition accurately and prescribe the correct dosage.

No, you should not drink alcohol while taking this medication. Alcohol can increase the risk of side effects, such as dizziness and lightheadedness.

No, you should not drink grapefruit juice while taking this medication. Grapefruit juice can interact with this medication and increase the risk of side effects.

Megoal Trio 20mg/10mg/12.5mg Tablet may interact with certain medications. So, you should talk to your doctor before taking any over-the-counter medications, such as pain relievers or cold medications, while taking this medication.

Your doctor will monitor your blood pressure to evaluate if this medicine is effective. You may also experience less symptoms, such as headaches or dizziness.

The long-term effects of taking this medicine remain unclear. However, the majority of people who use this drug do not encounter any serious long-term negative effects.

Megoal Trio 20mg/10mg/12.5mg Tablet is a combination of three medicines, namely: Olmesartan medoxomil, Cilnidipine, and Chlorthalidone.

Megoal Trio 20mg/10mg/12.5mg Tablet is not recommended in children. The safety and efficacy of Megoal Trio 20mg/10mg/12.5mg Tablet in children have not yet been established.

Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Megoal Trio 20mg/10mg/12.5mg Tablet is pregnancy risk category D medicine which may cause harm to the fetus or unborn baby. So, when pregnancy is detected, discontinue Megoal Trio 20mg/10mg/12.5mg Tablet as soon as possible and consult the doctor.

Country of origin

India
Other Info - ME60080

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