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Melalite Plus Cream is used to treat melasma (a type of skin problem). It works by decreasing the amount of melanin, promoting cell renewal and inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. In some cases, this medicine may cause side effects such as burning, itching, or stinging sensation of the skin. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Nicholas Piramal India Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Melalite Plus Cream

Melalite Plus Cream is a specialised topical prescription medicine designed to treat moderate-to-severe melasma, senile lentigines, and other stubborn dark spots on the face. It works by targeting the root causes of uneven skin pigmentation, helping to lighten dark patches and restore an even skin tone. This medication is clinically formulated to combine multiple actions, making it highly effective for dermatological care.

To achieve the best results, you should apply Melalite Plus Cream consistently once a day, specifically at night, or as directed by your doctor. Since this treatment makes your skin highly sensitive to environmental factors, integrating daily broad-spectrum sun protection and wearing protective hats can significantly enhance your results. Always wash your face with a mild, soap-free cleanser before applying the cream.

While using Melalite Plus Cream, you may experience mild skin peeling, redness, or a slight burning sensation, which are typical signs of skin renewal. However, if you experience severe blistering, swelling, or a dark blue-black discolouration on the treated areas, you must stop applying the cream and consult your doctor immediately.

Do not use this medicine if you have a history of allergic reactions to skin-lightening products or if you have open wounds, sunburn, or active eczema on your face. It is also important to tell your doctor if you have a history of skin cancer or other chronic skin conditions before starting this treatment.

Avoid using other drying skin products, alcohol-based toners, or harsh chemical peels while using Melalite Plus Cream, as these can trigger severe skin irritation. Pregnant and breastfeeding women must not use this medication, as certain active components can be absorbed through the skin and may harm the baby. If you are elderly or have highly sensitive skin, discuss customised application plans with your doctor or pharmacist.

Uses of Melalite Plus Cream

Melalite Plus Cream is used to treat moderate-to-severe melasma, senile lentigines, and other stubborn dark spots on the face. The detailed uses are as follows:

  • Melasma: Melalite Plus Cream helps lighten dark, patchy skin discolouration that typically appears on the cheeks, forehead, and upper lip due to hormonal changes or sun exposure.
  • Post-inflammatory hyperpigmentation: This cream works to fade stubborn dark spots and blemishes that remain after acne, skin injuries, or inflammatory skin conditions have healed.
  • Senile lentigines (age spots): It targets and reduces the appearance of flat, brown-to-black spots that develop on sun-exposed areas of the skin over time.

Key Benefits

Melalite Plus Cream brings a visible improvement to your skin's appearance, helping you regain confidence with a clearer, more even complexion.

  • Faded dark spots faster: Accelerating the shedding of dull, pigmented cells, this medication provides faster results than standard cosmetic creams, showing noticeable clearing of dark spots within a few weeks of consistent use.
  • Reduces irritation: Unlike single-ingredient lightening treatments that can cause significant irritation, Melalite Plus Cream contains a soothing agent that actively minimises redness and swelling.
  • Smoother, more even skin: You can undergo the skin-renewal process with minimal discomfort, experiencing smoother skin texture and uniform skin tone without severe inflammation.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Apply a small amount of Melalite Plus Cream to the affected area as directed by your doctor.
  • Wash your face with mild soap and pat dry before using Melalite Plus Cream.

How Melalite Plus Cream Works

Melalite Plus Cream works through the combined action of three distinct active components that target hyperpigmentation at different stages. The first component is a skin-lightening agent that penetrates deep into the skin cells to block the chemical pathway responsible for producing melanin, the pigment that causes dark patches. The second component is a powerful vitamin A derivative that promotes rapid skin cell turnover. It encourages the skin to shed older, darkened cells on the surface and replace them with fresh, unpigmented skin cells from beneath. This process effectively brings the dark spots to the surface where they can be washed away. The third component is a mild corticosteroid that acts as an anti-inflammatory agent. Its primary role is to soothe the skin and prevent the redness, swelling, and itching that often occur when the skin is undergoing rapid renewal and lightening. Together, these three actions deliver a comprehensive, highly effective treatment for hyperpigmentation.
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Alcohol

Caution

The interaction of alcohol with Melalite Plus Cream is unknown. Please consult a doctor before consuming alcohol while using Melalite Plus Cream.

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Melalite Plus Cream is given to a pregnant woman only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Melalite Plus Cream is excreted in human milk. Please consult a doctor before using Melalite Plus Cream while breastfeeding.

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Driving

Safe if prescribed

Melalite Plus Cream usually does not affect your ability to drive or operate machinery.

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Liver

Caution

If you have any concerns regarding the use of Melalite Plus Cream in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Melalite Plus Cream in patients with kidney problems, please consult a doctor.

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Children

Caution

Melalite Plus Cream is not recommended for children below 10 years of age as the safety and effectiveness were not established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before taking Melalite Plus Cream. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Melalite Plus Cream should be used in the elderly patients only when prescribed by a doctor. If you have any concerns about using Melalite Plus Cream for geriatrics, please consult a doctor.

What if I have taken an overdose of Melalite Plus Cream

Applying too much Melalite Plus Cream will not make it work faster and can cause severe skin peeling, redness, and discomfort. If you accidentally apply an excessive amount, wash the area thoroughly with cold water. If the medication is accidentally swallowed, seek immediate medical attention.

Diet & Lifestyle Advise

  • Use sunscreen daily: Apply a broad-spectrum sunscreen with an SPF of 30 or higher every morning, even on cloudy or rainy days, as UV rays trigger melanin production and worsen dark spots.
  • Protect your skin: Wear protective clothing, such as a wide-brimmed hat and sunglasses, when outdoors to shield your face from direct sun exposure.
  • Avoid harsh skincare products: Avoid using harsh facial scrubs, exfoliating brushes, or chemical peels, as your skin will be extra sensitive during treatment.
  • Moisturise regularly: Use gentle, non-comedogenic, and fragrance-free moisturisers regularly to combat dryness and support the skin's natural barrier.
  • Stay hydrated: Stay hydrated by drinking plenty of water daily to support healthy skin regeneration from within.
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Have a query?

How Soon It Starts Working

The time required for Melalite Plus Cream to start to work: The time required for Melalite Plus Cream to show its action is unknown. The time for which the effects of Melalite Plus Cream last: The duration of action for Melalite Plus Cream is clinically unknown.

What if you forget to take Melalite Plus Cream

If you miss an evening application, skip the missed dose and apply the medicine the following evening at your regular time. Do not apply a double amount of the cream to make up for a missed dose, as this will only increase skin irritation.

Storage

•Store Melalite Plus Cream at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tube tightly closed when not in use to prevent the cream from oxidising and losing its strength.

Drug Warnings

  • Avoid sun exposure: Avoid sunlamps, tanning beds, and prolonged sun exposure; this medication makes your skin highly prone to sunburn.
  • Do not apply to damaged skin: Do not apply Melalite Plus Cream to areas of the skin that are cut, scraped, sunburned, windburned, or affected by active eczema.
  • Avoid contact with eyes and mouth: Be extremely careful to avoid getting the cream in your eyes, nose, mouth, or on open wounds; if accidental contact occurs, rinse thoroughly with water.
  • Use only as prescribed: Do not use this product for longer than the period prescribed by your doctor to avoid the risk of permanent skin thinning or darkening.
  • Perform a patch test: Perform a small patch test on a hidden area of your skin, like the inner arm, before your first full-face application to check for any severe allergic reactions.

Drug-Drug Interactions

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Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Other topical peeling agents (like salicylic acid, sulfur, or resorcinol): May cause severe skin dryness, peeling, and irritation when used together with Melalite Plus Cream.
  • Medications that increase sun sensitivity (like certain antibiotics or diuretics): They may significantly increase your risk of severe sunburn and skin damage.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Alcohol consumption: It may increase skin flushing, dilation of blood vessels, and skin sensitivity, worsening the redness caused by this cream.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS TOPICAL]

FAQs

Melalite Plus Cream contains Hydrocortisone (corticosteroid), Hydroquinone (skin lightening agent) and Tretinoin (retinoids). Hydrocortisone works by acting inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching and swelling. Hydroquinone works by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Tretinoin works by increasing the renewal of skin cells which helps in the natural exfoliation of the skin’s outer layers.
Melalite Plus Cream may cause skin irritation, burning sensation or itching at the site of application. However, if the irritation persists or worsens, stop using Melalite Plus Cream and consult a doctor.
Melalite Plus Cream may increase the skin sensitivity to sunlight in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn.
You are advised to use moisturizer in the morning every day to restore the fat barrier of the skin that protects the skin from damage. Melalite Plus Cream may make skin more sensitive to extreme weather conditions such as cold and wind. Therefore, wear protective clothing and use moisturizer as required. However, please consult a doctor before using moisturizing lotions or any other products with Melalite Plus Cream.
You are not recommended to use Melalite Plus Cream with benzoyl peroxide, hydrogen peroxide or any other peroxide products as it may cause staining of the skin which can be usually removed with soap and water. However, please consult a doctor before using Melalite Plus Cream with other medicines.
You are not recommended to stop using Melalite Plus Cream without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Melalite Plus Cream for as long as your doctor has prescribed it and if you experience any difficulty while taking Melalite Plus Cream, please consult your doctor.
No, you should not use this medication if you are pregnant, planning to become pregnant, or breastfeeding, as the active ingredients can be absorbed through the skin and may cause harm to your baby. Talk to your doctor for safer alternatives.
Mild peeling is a normal part of how this medicine works to renew your skin. You can manage this by applying a gentle, fragrance-free moisturiser during the day and ensuring you are not applying too much cream at night. If the peeling becomes painful or raw, talk to your doctor.
Yes, you can wear makeup during the day, but you should not apply makeup directly over Melalite Plus Cream at night. In the morning, wash your face thoroughly, apply your moisturiser and sunscreen, and then you may apply makeup as usual. Talk to your doctor for product recommendations.
No, you should not apply this cream during the day because its ingredients make your skin extremely sensitive to sunlight, which can lead to severe sunburns or make your dark spots worse. Skip the missed dose and resume your regular application the following night. Talk to your doctor if you have further concerns.
While Melalite Plus Cream is highly effective at fading dark patches, melasma can return if your skin is exposed to sunlight or hormonal changes. Long-term sun protection is essential to maintain your results after finishing treatment. Talk to your doctor about a long-term maintenance plan.
No, you should only apply a thin layer of Melalite Plus Cream directly to the dark spots and a tiny area of surrounding skin. Do not apply it to unaffected areas of your face as it can unnecessarily lighten normal skin. Talk to your doctor if you have widespread dark patches.
In some cases, temporary mild darkening can happen due to initial skin irritation or if you are not using enough sun protection. However, rare severe darkening can occur, so if your skin darkens significantly or turns blue-black, stop using the cream immediately and talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

401, Lsc, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 In.
Other Info - MEL0012
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