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Mephalip Tablet is a combination medicine used in the treatment of neuropathic pain. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like nausea, vomiting, diarrhoea, and stomach upset. Inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ALPHA LIPOIC ACID-100MG+FOLIC ACID-1.5MG+METHYLCOBALAMIN-1500MCG+PYRIDOXINE HYDROCHLORIDE-3MG

Manufacturer/Marketer :

Indiabulls Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Mephalip Tablet

Mephalip Tablet is a nutritional supplement primarily used to treat and prevent neuropathies, such as diabetic nerve damage and nutritional deficiencies. It helps reduce symptoms like numbness, tingling, and burning sensations in the hands and feet by protecting and regenerating damaged nerves. This combination supports the body's natural nerve conduction and cellular energy production.

For the best results, take Mephalip Tablet consistently every day at the same time, either with or without food as advised by your doctor. Swallow the tablet whole with a glass of water, and do not skip doses even if you start feeling better. Incorporating a balanced diet low in sugar and regular, low-impact exercise can significantly help with the results and enhance your recovery.

While taking Mephalip Tablet , you might experience mild side effects like an upset stomach, nausea, or a mild skin rash. If you experience severe symptoms such as difficulty breathing, swelling of the face, or extreme dizziness, seek immediate medical care. Always discuss any unusual reactions with your healthcare provider promptly.

Before starting Mephalip Tablet , talk to your doctor if you have a history of kidney disease, liver issues, diabetes, or thyroid disorders. Do not take this medicine if you have a known allergy to any of its active components. It is also important to disclose any upcoming surgeries, as certain ingredients may affect blood sugar levels during medical procedures.

Limit or avoid alcohol while taking Mephalip Tablet , as alcohol reduces vitamin absorption and can worsen nerve damage. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor before using this supplement to ensure it is safe for your specific needs.

Uses of Mephalip Tablet

Mephalip Tablet is used to treat and prevent neuropathies. The detailed uses of Mephalip Tablet are as follows:

  • Diabetic Neuropathy: Helps protect nerve fibres from high blood sugar damage and relieves burning pain and numbness in patients with diabetes.
  • Nutritional Deficiencies: Replenishes essential B-vitamins and antioxidants crucial for nerve health and proper red blood cell formation.
  • Peripheral Neuropathy: Aids in restoring sensation and reducing chronic pain in the limbs caused by physical injury or systemic health issues.
  • Megaloblastic Anaemia: Assists in the proper production of healthy red blood cells, helping to reduce fatigue and physical weakness.

Key Benefits

Mephalip Tablet helps support healthy nerve function by promoting nerve repair and relieving the symptoms of nerve damage. With regular use, it helps reduce nerve pain, improves mobility, and supports overall energy and well-being.

  • Relieves Nerve Pain: By addressing the underlying causes of nerve damage, this medicine helps reduce burning, tingling, and shooting pain in the hands and feet, allowing for more comfortable movement.
  • Supports Nerve Repair: This medicine helps rebuild the protective covering around nerve cells, promoting healthier nerve function and supporting recovery from nerve damage.
  • Boosts Energy and Physical Function: The essential vitamins help support cellular energy production, reducing fatigue and improving daily physical performance and overall vitality.

Directions for Use

  • Mephalip Tablet can be taken with or without food, or as advised by the doctor.
  • The daily dose of Mephalip Tablet depends on individual health needs. Follow your doctor’s instructions regarding dosage and timing for better effectiveness.
  • Swallow Mephalip Tablet as a whole with a glass of water.
  • Do not crush, chew, or break Mephalip Tablet .

How Mephalip Tablet Works

Mephalip Tablet works through the combined action of its active components to repair, protect, and maintain healthy nerves. Each ingredient plays a specific role in supporting the nervous system: Alpha lipoic acid acts as a potent antioxidant that neutralises harmful free radicals, improves blood flow to the nerves, and helps lower oxidative stress associated with high blood sugar levels. Methylcobalamin is an active form of Vitamin B12 that helps produce myelin, the protective sheath surrounding nerve fibres, which is essential for proper nerve signal transmission. Folic acid is essential for DNA synthesis and cellular repair, working alongside other B-vitamins to lower levels of homocysteine, a compound that can damage blood vessels and nerves when elevated. Pyridoxine hydrochloride (Vitamin B6) plays a vital role in the synthesis of neurotransmitters, which are chemical messengers that transmit signals throughout your nervous system.
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Alcohol

Caution

Avoid consumption of alcohol while taking Mephalip Tablet as it may lead to unpleasant side effects.

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Pregnancy

Consult your doctor

Consult your physician before taking Mephalip Tablet if you are pregnant or planning a pregnancy.

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Breast Feeding

Consult your doctor

Consult your physician before taking Mephalip Tablet , your doctor will decide whether Mephalip Tablet can be taken by breastfeeding mothers or not.

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Driving

Safe

Mephalip Tablet does not affect your ability to drive.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your physician if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your physician if you have kidney impairment or any concerns regarding this.

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Children

Caution

Mephalip Tablet is not recommended for children as safety and efficacy have not been established.

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Heart

Safe if suggested

Mephalip Tablet is generally considered safe for heart patients when used at the recommended dose. However, please consult your doctor if you have any concerns.

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Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of Mephalip Tablet in elderly patients.

What if I have taken an overdose of Mephalip Tablet

If you suspect an overdose or experience severe symptoms like extreme drowsiness, confusion, or severe stomach upset, seek immediate medical attention.

Diet & Lifestyle Advise

  • Maintain stable blood sugar levels by eating high-fibre foods, whole grains, and lean proteins, which helps prevent further nerve damage.
  • Incorporate foods rich in B-vitamins, such as green leafy vegetables, eggs, and fortified cereals, to support your treatment.
  • Engage in regular, low-impact exercises like walking or swimming to improve blood circulation to your nerves and reduce neuropathic pain.
  • Inspect your feet daily for any cuts, blisters, or redness, as reduced sensation from neuropathy can make it hard to feel minor injuries.
  • Avoid smoking, as tobacco use constricts blood vessels and worsens peripheral nerve damage.
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Have a query?

How Soon It Starts Working

The time required for Mephalip Tablet to start to work: The time required for Mephalip Tablet to show its action is unknown.

The time for which the effects of Mephalip Tablet last: The duration of action for Mephalip Tablet is clinically unknown.

What if you forget to take Mephalip Tablet

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Mephalip Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F). • Keep all medicines safely out of the reach of children and pets.

Drug Warnings

  • Always inspect the packaging for any signs of tampering or damage before taking the tablet.
  • Inform any healthcare provider you visit, including dentists and surgeons, that you are taking this supplement, as it can affect certain laboratory tests or blood sugar levels.
  • Monitor your blood sugar levels closely if you have diabetes, as alpha lipoic acid can increase the effect of insulin or other diabetes medications.
  • Do not start, stop, or change the dose of any other medications without consulting your doctor or pharmacist first.
  • Avoid taking antacids or mineral supplements (containing iron, calcium, or magnesium) at the same time as Mephalip Tablet , as they can interfere with its absorption. Space them at least 2 hours apart.

verifiedApollotooltip
  • Diabetes medications (like insulin, metformin): Combining these with Mephalip Tablet may cause blood sugar levels to drop too low.
  • Chemotherapy medications: Certain antioxidants in this medicine may interfere with the effectiveness of some cancer treatments.
  • Thyroid medications (like levothyroxine): Alpha lipoic acid may lower thyroid hormone levels, requiring close monitoring.
  • Seizure medications (like phenytoin, phenobarbital): Pyridoxine (Vitamin B6) may decrease the effectiveness of these medications.
     

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  • Alcohol: Drinking alcohol reduces the absorption of B-vitamins and can worsen symptoms of nerve damage.
     

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Mephalip Tablet is used to treat neuropathic pain associated with diabetic neuropathy.
Mephalip Tablet is a combination of four drugs: Alpha lipoic acid, folic acid, methylcobalamin and pyridoxine. Together, Mephalip Tablet helps in providing relief from neuropathic pain by augmenting the health and vitality of nerve and muscle cells.
Mephalip Tablet is used to treat diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly causes pain in the legs and feet.
Mephalip Tablet may be used to treat trigeminal neuralgia. It is a condition in which the trigeminal nerve is affected, leading to pain.
To treat your condition effectually, continue taking Mephalip Tablet for as long as recommended. Do not be reluctant to speak with your physician if you experience any difficulty while taking Mephalip Tablet .
Neuropathic pain can be challenging to live with. Make sure you keep a healthy mindset, get regular exercise, invest in a balanced and nutritious diet rich in lean meats, oily fish, nuts, whole grains, green leafy vegetables and fruit. Avoid excess alcohol and smoking as this can aggravate pain states. Talk to a professional and join a support group if you ever feel the need.
Yes, you can take Mephalip Tablet with or without food. If you experience an upset stomach, taking it with a meal can help reduce discomfort. Talk to your doctor if stomach issues persist.
Mephalip Tablet should only be used during pregnancy if clearly needed and suggested by your doctor. Talk to your doctor to evaluate the benefits and risks.
It is best to avoid or limit alcohol consumption while taking Mephalip Tablet . Alcohol can interfere with the absorption of the active vitamins and can worsen nerve damage. Talk to your doctor for personalised advice.
Weight gain is not a commonly reported side effect of Mephalip Tablet . If you notice unexpected weight changes, talk to your doctor to find the underlying cause.
Yes, Mephalip Tablet is often suggested for diabetic nerve pain. However, because it contains alpha lipoic acid, it may lower your blood sugar levels. Monitor your blood glucose closely and talk to your doctor about adjusting your diabetes medications if needed.
A mild rash can occasionally occur. However, if the rash is severe, itchy, or accompanied by swelling or breathing difficulties, stop taking the medicine and seek medical help immediately. Talk to your doctor for guidance.
You should avoid taking other supplements containing high doses of B-vitamins or antioxidants unless recommended by your healthcare provider, to prevent accidental overdose. Talk to your doctor or pharmacist before combining supplements.

Disclaimer

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Reference

  1. WebMD Medical Reference Review Board. Alpha Lipoic Acid Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  2. National Center for Biotechnology Information (NCBI). Nbk441923 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 021446S026,022488S005Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. U.S. Food and Drug Administration (FDA). Download [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  5. National Health Service (NHS). Folic Acid - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  6. National Center for Biotechnology Information (NCBI). Nbk557436 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  7. Mecobalamin Template Oral Website. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Indiabulls Pharmaceuticals Limited Is M €“ 62 & 63, First Floor, Connaught Place, New Delhi €“ 11000
Other Info - MEP0186

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