Apollo
logo
Not for online sale
compositionComposition:MEPHENTERMINE-30MG
prescription
Prescription Medicine
info

Mephentermine Injection 1ml is used to treat hypotension (low blood pressure). Besides this, it is also indicated to treat hypotensive states, such as circulatory failure during spinal anaesthesia or drug-induced hypotension. It contains Mephentermine, which helps to release a chemical messenger (adrenaline), that compresses the blood vessels. It increases blood pressure rapidly by increasing the heart's pumping capacity and narrowing the heart's blood vessels. Some people may experience side effects such as systemic hypertension (high blood pressure), anxiety, insomnia (difficulty in sleeping), and CNS stimulation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

Read more
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

MEPHENTERMINE-30MG

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Mephentermine Injection 1ml

The medication, Mephentermine Injection 1ml, is an injection used to maintain and raise blood pressure during medical procedures or anaesthesia. It is designed to treat sudden and dangerous drops in blood pressure, ensuring that vital organs receive an adequate supply of oxygen-rich blood. This medicine is primarily used in emergency or controlled clinical settings under direct medical supervision.

Because this medicine is given as an injection or infusion, it is not used on a regular daily schedule at home. It is injected by a healthcare provider when needed and does not require any special food considerations before or after administration. Following a well-hydrated diet and keeping your fluid levels stable can support your blood pressure recovery after receiving this treatment.

Some patients may experience mild side effects like a temporary feeling of nervousness, a faster heart rate, or trouble sleeping. It is important to notify your healthcare provider immediately if you experience severe headaches, extreme dizziness, or sudden chest pain. Your medical team will monitor your vital signs continuously to ensure your safety during treatment.

Do not receive this medicine if you have severe high blood pressure, an overactive thyroid gland, or a specific tumour of the adrenal glands. It is also not suitable for patients with a history of severe cardiovascular diseases. Always share your complete medical history with your doctor before any planned medical procedure.

This medicine can interact with certain antidepressants, especially monoamine oxidase inhibitors, leading to a dangerous rise in blood pressure. You should avoid alcohol before and after treatment to prevent unpredictable shifts in your blood pressure levels. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor to discuss the risks and benefits of this medicine.

Uses of Mephentermine Injection 1ml

Mephentermine Injection 1ml is used to maintain and raise blood pressure during medical procedures or anaesthesia. The detailed uses of Mephentermine Injection 1ml are as follows:

  • Low blood pressure (hypotension) during anaesthesia: Mephentermine Injection 1ml helps raise blood pressure when it drops significantly during spinal anaesthesia or surgical procedures, keeping your vital organs functioning safely.
  • Circulatory collapse: Mephentermine Injection 1ml is injected to support blood pressure and stabilise circulation in critical care situations where blood pressure falls to dangerous levels.
     

Key Benefits

Mephentermine Injection 1ml helps restore and maintain blood pressure during medical emergencies and surgical procedures. By supporting adequate blood flow to vital organs, it helps improve circulation and reduces the risk of complications associated with low blood pressure.

  • Helps Restore Blood Pressure Quickly: By increasing blood pressure when it falls too low, Mephentermine Injection 1ml helps improve circulation and reduce symptoms such as dizziness, light-headedness, and fainting.
  • Supports Blood Flow to Vital Organs: By maintaining adequate blood circulation, Mephentermine Injection 1ml helps ensure that essential organs, including the brain, heart, and kidneys, continue to receive sufficient oxygen and nutrients during medical procedures.
  • Promotes Safer Recovery During Medical Care: By stabilising blood pressure during surgery or other critical situations, Mephentermine Injection 1ml helps support a safer treatment process and contributes to a smoother recovery following anaesthesia or other medical interventions.
     

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Mephentermine Injection 1ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Mephentermine Injection 1ml Works

Mephentermine Injection 1ml contains mephentermine. It works by prompting the body to release its own natural chemical messengers, specifically norepinephrine, into the bloodstream. These natural chemicals act on the walls of your blood vessels, causing them to narrow or squeeze. At the same time, they stimulate the heart muscle to beat with more strength. Together, the narrowing of the blood vessels and the increased pumping action of the heart quickly raise your blood pressure, restoring healthy blood flow throughout your body.
bannner image

Alcohol

Caution

It is not known if alcohol interacts with Mephentermine Injection 1ml. Please consult your doctor if you have any concerns regarding this.

bannner image

Pregnancy

Unsafe

Mephentermine Injection 1ml may increase uterine contractions in pregnant women, especially during the third trimester. Inform your doctor if you are pregnant before taking Mephentermine Injection 1ml.

bannner image

Breast Feeding

Unsafe

It is unknown whether Mephentermine Injection 1ml is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

bannner image

Driving

Caution

It is not known whether Mephentermine Injection 1ml affects the ability to drive. Do not drive if you experience symptoms affecting your ability to concentrate and react.

bannner image

Liver

Caution

Mephentermine Injection 1ml to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

bannner image

Kidney

Caution

Mephentermine Injection 1ml should be taken with caution, especially if you have a history of Kidney diseases or conditions. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

bannner image

Children

Caution

Mephentermine Injection 1ml is not recommended for children below 18 years of age. However, please consult a doctor before giving Mephentermine Injection 1ml to children.

bannner image

Heart

Unsafe

Mephentermine Injection 1ml is not recommended for use in cardiac patients due to the cardiovascular effects.

bannner image

Geriatrics

Caution

Mephentermine Injection 1ml should be used with caution in elderly patients due to the risk of hypertension and increased heart rate.

What if I have taken an overdose of Mephentermine Injection 1ml

Because this medicine is given under close medical supervision, an overdose is rare. However, if too much medicine is injected, it can lead to symptoms like a sudden, severe spike in blood pressure, intense headache, or a very fast heart rate. The healthcare team is trained to recognise these signs and will treat them immediately with supportive medical care.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water as recommended by your healthcare provider to help support natural blood volume and pressure.
  • Avoid sudden movements: When waking up or resting, sit up slowly and wait a moment before standing to prevent brief dizzy spells.
  • Limit or avoid alcohol: Alcohol can cause unpredictable blood pressure changes and should be avoided before and after procedures involving this medication.
  • Follow nutritional guidance: Follow any specific dietary plans, including sodium intake recommendations, provided by your medical team.
     
health query

Have a query?

How Soon It Starts Working

The time required for Mephentermine Injection 1ml to start to work: The time required for Mephentermine Injection 1ml to start to work is 5 to 15 minutes intramuscularly and immediately with IV administration. The time for which the effects of Mephentermine Injection 1ml last: The effect of Mephentermine Injection 1ml lasts for 4 hours intramuscularly and 30 minutes intravenously.

What if you forget to take Mephentermine Injection 1ml

Since this medication is given by a medical professional in a clinical setting when needed, it is highly unlikely that you will miss a dose. If you suspect an infusion has been delayed or missed, inform your healthcare provider immediately.

Storage

•It should be kept at a controlled room temperature, ideally between 15°C to 30°C.

Drug Warnings

  • Check the solution: Always ensure the injection solution is completely clear and colourless. Do not use if you see any particles or discolouration.
  • Ensure professional administration: This medicine must only be injected by a trained nurse or doctor in an appropriate medical facility.
  • Continuous monitoring: Your heart rate and blood pressure must be monitored closely during and immediately after the injection.
  • Practice syringe safety: Ensure all needles and syringes are sterile, used only once, and disposed of immediately in a designated sharps container.
  • Report injection site issues: Tell your medical team immediately if you feel pain, burning, or swelling where the needle was inserted.
     

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

  • Monoamine Oxidase Inhibitors (MAOIs): Combining this medicine with MAOIs can cause a severe, life-threatening spike in blood pressure.
  • Tricyclic Antidepressants: May increase the risk of high blood pressure and abnormal heart rhythms.
  • Other Blood Pressure Medicines: Using this along with other medications that raise blood pressure can lead to excessively high pressure levels.


Drug-Food Interactions

  • Alcohol: Drinking alcohol can interfere with blood pressure regulation and increase the risk of adverse cardiovascular events.


Drug-Disease Interactions

  • High Blood Pressure (Hypertension): May worsen existing hypertension to dangerous levels.
  • Overactive Thyroid (Hyperthyroidism): Can increase the risk of rapid, irregular heartbeats.
  • Heart Disease: May put extra strain on the heart, worsening conditions like coronary artery disease.
  • Pheochromocytoma: Can trigger sudden and dangerous blood pressure spikes in individuals with this adrenal gland tumour.
     
MephentermineIsocarboxazid
Critical

Drug-Drug Interactions

Login/Sign Up

How does the drug interact with Mephentermine Injection 1ml Injection 1ml:
Taking Procarbazine with Mephentermine Injection 1ml together may increase the hypertensive activities of Mephentermine Injection 1ml.

How to manage the interaction:
Taking Mephentermine Injection 1ml with Procarbazine is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting a doctor.
MephentermineIsocarboxazid
Critical
How does the drug interact with Mephentermine Injection 1ml Injection 1ml:
Taking isocarboxazid and Mephentermine Injection 1ml together can increase the risk of high blood pressure.

How to manage the interaction:
Taking Mephentermine Injection 1ml with Isocarboxazid is not recommended, but can be taken if prescribed by the doctor. However, consult your doctor immediately if you experience symptoms such as severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting a doctor.
MephenterminePhenelzine
Critical
How does the drug interact with Mephentermine Injection 1ml Injection 1ml:
Taking Phenelzine with Mephentermine Injection 1ml together may increase the hypertensive activities of Mephentermine Injection 1ml.

How to manage the interaction:
Taking Mephentermine Injection 1ml with Phenelzine together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these signs - headache, trouble seeing clearly, feeling confused or having seizures, chest pain, feeling sick, sudden numbness or weakness, difficulty speaking, having a fever, sweating a lot, feeling dizzy or passing out - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mephentermine Injection 1ml Injection 1ml:
When Mephentermine Injection 1ml is combined with Selegiline, may increase the risk of high blood pressure.

How to manage the interaction:
Mephentermine Injection 1ml with Selegiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mephentermine Injection 1ml Injection 1ml:
Taking linezolid and Mephentermine Injection 1ml together may cause high blood pressure.

How to manage the interaction:
Taking Mephentermine Injection 1ml with Linezolid is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
MephentermineIobenguane (131i)
Severe
How does the drug interact with Mephentermine Injection 1ml Injection 1ml:
Co-administration of Iobenguane (131i) and Mephentermine Injection 1ml together can decrease the effectiveness of Mephentermine Injection 1ml.

How to manage the interaction:
There may be a possibility of interaction between Mephentermine Injection 1ml and Iobenguane (131i), but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Habit Forming

No

Therapeutic Class

[ANTIHYPOTENSIVES]

FAQs

Mephentermine Injection 1ml is used to treat hypotension (low blood pressure) and is also indicated to treat hypotensive states, such as circulatory failure during spinal anaesthesia or drug-induced hypotension.
Do not stop taking Mephentermine Injection 1ml on your own. You are advised to take Mephentermine Injection 1ml for as long as your doctor has prescribed it for you depending on your medical condition. Do not be hesitant to speak with your doctor if you experience any difficulty while taking Mephentermine Injection 1ml.
Do not take Mephentermine Injection 1ml if you are pregnant or planning for pregnancy unless prescribed by a doctor. Your doctor will prescribe Mephentermine Injection 1ml only if the benefits outweigh the risks.
Antidepressants, along with Mephentermine Injection 1ml, especially monoamine oxidase inhibitors (MAOI’s) may prolong and increase the effects of Mephentermine Injection 1ml. Consult your doctor before taking Mephentermine Injection 1ml with other medicines to avoid unpleasant side-effects.
Systemic hypertension (high blood pressure), Anxiety, Insomnia (difficulty in sleeping), CNS stimulation are the common side-effects of Mephentermine Injection 1ml.Â
A person should tell their doctor if they have a history of heart disease, overactive thyroid, shock, high blood pressure, persistent and lasting illness, during pregnancy, and breastfeeding.
It is given as an injection or infusion directly into a vein or muscle by a qualified healthcare professional in a hospital setting. Talk to your doctor to learn more.
It is generally not recommended if you already have high blood pressure, as it can raise your pressure even further. Talk to your doctor to discuss safer alternatives.
When injected into a vein, it works almost immediately to raise blood pressure and stabilize your circulation. Talk to your doctor for more details on what to expect.
A fast heartbeat is a common side effect of this medicine. Your clinical team will monitor you closely during treatment, but you should tell them immediately if you feel your heart pounding. Talk to your doctor if you have pre-existing heart concerns.
No, you should not drive immediately after receiving this injection, as you may feel dizzy or tired from the medicine or the medical procedure itself. Talk to your doctor about when it is safe to drive.
No, this medication is designed only for professional clinical use and must be injected by a trained healthcare provider. Talk to your doctor or pharmacist if you require home-care options.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Mephentermine Sulfate Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Mephentermine Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Mephentermine Sulphate Injection Manufacturers PAN India, Suppliers. [Accessed on 02 Jun. 2026]Check here
  4. Ministry of Health and Family Welfare. National Formulary of India (NFI) 2021. 6th ed. New Delhi, India: IPC; 2021. Clinical Drug Monographs: Termin 30Mg Injection
  5. Westfall TC, WestfallIn DP Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, eds. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802 / 1901, Plot No. C-70, G-Block,Bandra Kurla Complex, Bandra (East),Mumbai,Maharashtra,INDIA,400051.
Other Info - MEP0033
whatsapp Floating Button