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compositionComposition:MEDROXYPROGESTERONE-10MG
prescriptionPrescription Medicine
Meprate Tablet 10's
Meprate Tablet 10's
Meprate Tablet 10's
Meprate Tablet 10's

Meprate Tablet is used to treat the absence of menstrual periods (amenorrhea) and abnormal uterine bleeding. Besides this, it also prevents endometrial hyperplasia (thickening of the uterine lining with the risk of cancer) and overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MEDROXYPROGESTERONE-10MG

Manufacturer/Marketer :

Serum Institute Of India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Meprate Tablet

Meprate Tablet is used to treat the absence of menstrual periods (amenorrhea) and abnormal uterine bleeding. It also prevents endometrial hyperplasia (thickening of the uterine lining with the risk of cancer) and overgrowth in the lining of the uterus in postmenopausal women.

Meprate Tablet contains medroxyprogesterone, which replaces the normal hormone medroxyprogesterone that functions in the body and treats associated symptoms.

Take Meprate Tablet as advised by your doctor. Meprate Tablet may cause side effects like breast tenderness, headaches, migraines, mood swings, depression, acne, abdominal pain, back pain, and vaginal bleeding. If the side effects are persistent, reach out to your doctor.

If you are taking any other medicine or are allergic to any medication, please inform your doctor. Make sure that before taking this medicine, you inform your doctor if you have or have had breast cancer, unusual bleeding in the vagina, liver disease, or any other health problems.

Uses of Meprate Tablet

Meprate Tablet is used to treat Amenorrhea, uterine bleeding, endometrial hyperplasia, and endometriosis. The detailed uses of Meprate Tablet are as follows:

  • Menstrual Cycle Regulation: Meprate Tablet helps to regulate irregular menstrual cycles, treating conditions like amenorrhea by stabilising hormonal imbalances and promoting a regular menstrual cycle.
  • Endometriosis Treatment: Meprate Tablet is also used to treat endometriosis symptoms, such as painful periods and irregular cycles, by regulating hormones and reducing discomfort.
  • Treatment of Abnormal Uterine Bleeding: By controlling hormone levels and possibly lowering excessive bleeding during menstruation, Meprate Tablet can help manage abnormal uterine bleeding.

Health Queries

I have irregular periods. Sometimes I have light bleeding before my expected date, but my full period still comes on time. What could be the reason for this?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

Light bleeding before your period is often caused by hormonal changes or ovulation spotting (light vaginal bleeding during the middle of the menstrual cycle) and is usually not serious. It may also occur due to stress, thyroid problems, or conditions such as polycystic ovary syndrome. If it persists or becomes heavy, please see a doctor for proper evaluation.

I had my period on 10 February, but after 10 days (24 February), I got my period again. What could be the reason for this irregular bleeding, and what medicine should I take?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Getting your period again 10 days after the previous one can sometimes happen due to hormonal imbalance, stress, sudden weight changes, thyroid issues, or side effects of certain medications. In many cases, it may also be mid-cycle spotting (ovulation bleeding), which is usually harmless. However, if the bleeding is heavy, painful, or happens repeatedly, it is best to consult a gynaecologist for proper evaluation. Avoid taking medicines on your own; the doctor may suggest hormonal tablets or tests if needed.

I have a fibroid measuring 60 by 65 mm, and my periods are very painful. What should I do?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

A fibroid of this size can cause painful periods and heavy bleeding. Try using a heating pad on the lower abdomen and ensure proper rest during painful episodes. Maintain a healthy diet and avoid excessive stress. Consult a gynaecologist to discuss suitable treatment options for pain relief and fibroid management.

I have PCOD and have not had my periods for the last 6 months, and I also want to lose weight. What should I do to regularise my periods and reduce my weight?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

PCOD can cause missed periods due to hormonal imbalance and irregular ovulation. Weight reduction through portion control, regular exercise, and limiting sugary and refined foods can help improve cycle regularity. Focus on steady lifestyle changes instead of crash dieting. Consult a doctor to check hormone levels and get proper treatment to regulate your cycle.

Have a query?

Directions for Use

  • Meprate Tablet can be taken with or without food, as advised by your doctor.
  • Your doctor will decide the appropriate dosage and timing of Meprate Tablet based on your medical condition.
  • Swallow Meprate Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

Key Benefits

When used as prescribed, Meprate Tablet may offer the following benefits:

For Amenorrhea:

  • Corrects progesterone insufficiency, which aids in the restart of menstrual cycles.
  • Controls the menstrual cycle in hormonally imbalanced women.
  • Helpful in treating secondary amenorrhea once pregnancy and other reasons have been ruled out.

For Abnormal Uterine Bleeding:

  • Controls the menstrual cycle.
  • Helps reduce heavy or prolonged bleeding.
  • Stabilizes the endometrium, the lining of the uterus.
  • Helps correct progesterone deficiency.
  • Helps prevent recurrent abnormal bleeding.

For Endometriosis:

  • Blocks the development of endometrial tissue outside of the uterus.
  • Lowers menstrual cramps and pelvic discomfort.
  • Reduces uncomfortable or heavy periods.
  • Reduces the size of endometriotic lesions.
  • Enhances quality of life by reducing symptoms.

How Meprate Tablet Works

Meprate Tablet contains medroxyprogesterone, which works by replacing the normal hormone medroxyprogesterone functions in the body and treating associated symptoms.

Storage

Store in a cool and dry place away from sunlight
Side effects of Meprate Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.

What if I have taken an overdose of Meprate Tablet

Do not take more than the prescribed dose of Meprate Tablet as it may cause an overdose. The symptoms of overdose include seizures (fits), vomiting, nausea, trouble breathing and altered mental status. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not use Meprate Tablet if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancer (breast or uterine cancer), or are undergoing estrogen plus progestin treatment.
  • Tell your doctor before using Meprate Tablet if you have had a heart attack, stroke, blood clot, liver problems, or kidney problems; are pregnant, breastfeeding or planning to get pregnant, have asthma, epilepsy, diabetes, migraine, endometriosis, lupus, heart problems, thyroid problems, or have high calcium levels in your blood.
  • Use caution while driving a motor vehicle, as dizziness or drowsiness may occur.
  • In some cases, using Meprate Tablet with estrogen may produce dementia among women aged 65 and older. Consult your physician if you notice memory problems.

Drug-Drug Interactions

verifiedApollotooltip
MedroxyprogesteroneAcitretin
Critical
MedroxyprogesteroneEtretinate
Critical

Drug-Drug Interactions

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MedroxyprogesteroneAcitretin
Critical
How does the drug interact with Meprate Tablet:
Coadministration of Acitretin with Meprate Tablet can increase the risk and severity of birth defects when taken by a pregnant woman.

How to manage the interaction:
Taking Acitretin with Meprate Tablet together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneEtretinate
Critical
How does the drug interact with Meprate Tablet:
Taking Meprate Tablet and Etretinate may cause severe birth defects if the mother takes the medication during pregnancy.

How to manage the interaction:
Using etretinate and Meprate Tablet together is not recommended, but can be taken if prescribed by a doctor. However, if you experience unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneTranexamic acid
Critical
How does the drug interact with Meprate Tablet:
Taking Meprate Tablet acetate with Tranexamic acid may increase the risk of blood clots.

How to manage the interaction:
Taking Meprate Tablet with Tranexamic acid is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
MedroxyprogesteroneTelaprevir
Severe
How does the drug interact with Meprate Tablet:
Taking telaprevir and Meprate Tablet may reduce the blood levels and effects of Meprate Tablet.

How to manage the interaction:
Although taking Meprate Tablet and Telaprevir together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as hot flashes, vaginal dryness, or abnormal bleeding, consult your doctor immediately. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneBoceprevir
Severe
How does the drug interact with Meprate Tablet:
Taking boceprevir and Meprate Tablet may, decrease the blood levels and effects of Meprate Tablet.

How to manage the interaction:
Although taking Meprate Tablet and Boceprevir together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult your doctor immediately. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneBrigatinib
Severe
How does the drug interact with Meprate Tablet:
Taking Meprate Tablet and Brigatinib may, reduce the blood levels and effects of Meprate Tablet.

How to manage the interaction:
Although taking Meprate Tablet and brigatinib together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience hot flashes(feeling of heat in the body), dryness, or unusual bleeding, don't hesitate to reach out to your doctor. Do not stop using any medications without a doctor's advice.
MedroxyprogesteroneBosentan
Severe
How does the drug interact with Meprate Tablet:
Taking Bosentan and Meprate Tablet may, reduce the blood levels and effects of Meprate Tablet.

How to manage the interaction:
Although there is a interaction between bosentan and Meprate Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience hot flashes(feeling of heat in the body), dryness, or unusual bleeding, don't hesitate to reach out to your doctor. Do not stop using any medications without a doctor's advice.
MedroxyprogesteroneTopiramate
Severe
How does the drug interact with Meprate Tablet:
When Meprate Tablet acetate is taken with Topiramate, it reduces the blood levels and effects of Meprate Tablet.

How to manage the interaction:
Co-administration of Meprate Tablet with Topiramate can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing symptoms like hot flashes, vaginal dryness, or abnormal bleeding, contact your doctor. Do not stop using any medications without talking to your doctor.
MedroxyprogesteroneGriseofulvin
Severe
How does the drug interact with Meprate Tablet:
Taking griseofulvin with Meprate Tablet may reduce blood levels and the effects of Meprate Tablet.

How to manage the interaction:
There may be a possibility of interaction between Griseofulvin and Meprate Tablet, but it can be taken if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, or if you think you might be pregnant while using birth control, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneAmprenavir
Severe
How does the drug interact with Meprate Tablet:
Taking Meprate Tablet with amprenavir may make amprenavir less effective.

How to manage the interaction:
There may be a possibility of interaction between Meprate Tablet and Amprenavir, but it can be taken if prescribed by a doctor. If you're having any unusual symptoms, it's important to contact your doctor right away. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Healthy eating habits:

  • Consume a diet rich in fruits, vegetables, whole grains, and lean meats.
  • Reduce bloating and fluid retention by limiting processed foods and salt.
  • Add meals high in calcium and vitamin D to maintain healthy bones.
  • Avoid eating too many sweet or fatty foods and stay hydrated.

Lifestyle changes:

  • Regularly engage in mild exercise to maintain a healthy weight.
  • Use relaxation techniques, yoga, or meditation to reduce stress.
  • Avoid smoking and binge drinking since these might disrupt hormone balance.
  • Observe routine medical examinations and take medication as directed.

Stress management:

  • Every day, engage in relaxation exercises like yoga, meditation, or deep breathing.
  • To maintain hormonal balance, make sure you get enough sleep and rest.

Habit Forming

No

Therapeutic Class

[HORMONES]

All Substitutes & Brand Comparisons

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Alcohol

Consult your doctor

There is not enough scientific data available for Meprate Tablet interaction with alcohol; hence, it is best to consult a doctor.

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Pregnancy

Unsafe

Avoid taking Meprate Tablet if you are pregnant or think you may be pregnant, as Meprate Tablet might affect the developing baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Meprate Tablet . Consult your doctor if you have any concerns.

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Driving

Caution

It is advised to drive with caution after taking Meprate Tablet as it may interfere with driving capabilities. It can make you feel drowsy.

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Liver

Caution

Meprate Tablet should be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Consult your doctor

There is not enough scientific data available for Meprate Tablet interaction with the kidney; hence, it is best to consult a doctor.

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Children

Unsafe

Meprate Tablet is not recommended for children below 12 years of age.

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Heart

Unsafe

Meprate Tablet is not recommended for use in heart patients. Please consult your physician.

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Geriatrics

Caution

Meprate Tablet should be avoided or taken with caution in geriatric patients as it can lead to serious adverse effects. Please consult your doctor before using Meprate Tablet .

FAQs

Meprate Tablet is used to treat the absence of menstrual periods (amenorrhea) and abnormal uterine bleeding. Besides this, it also prevents endometrial hyperplasia (thickening of the uterine lining with the risk of cancer) and overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.

Meprate Tablet helps in preparing the endometrium for pregnancy after ovulation. It thickens the lining of the endometrium to accept a fertilised egg. It also prevents muscle contractions of the uterus that would reject an egg in the uterus. So, if the body has a high progesterone level, ovulation will not occur then.

Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy, and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high levels of estrogen, and women can have decreased sex drive, weight gain, or gallbladder problems.

Yes, Meprate Tablet may cause weight gain. It can be due to water retention. If you feel that you are gaining a lot of weight while taking Meprate Tablet , please consult your doctor.

Do not use Meprate Tablet if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancers (breast or uterine cancer), or are undergoing estrogen plus progestin treatment. Tell your doctor before using Meprate Tablet if you had a heart attack, stroke, blood clot, liver problems, are pregnant, breastfeeding, or planning to get pregnant or are allergic to Meprate Tablet .

No, Meprate Tablet is not a contraceptive. It should not be used as an effective form of birth control to prevent pregnancy.

Meprate Tablet should be taken in the dose and duration as prescribed by the doctor.

Yes, Meprate Tablet is a synthetic pregnant steroid and a derivative of progesterone.

Less serious but common side effects of Meprate Tablet include headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps, bloating, nausea and vomiting, hair loss, fluid retention, and vaginal yeast infection.

Meprate Tablet is safe and effective if used as per prescribed dose and duration. The patient should follow doctor’s recommendations. Do not exceed the recommended daily dose.

No, Meprate Tablet does not cause withdrawal bleeding. However, if you notice symptoms such as bleeding or spotting even after completing the treatment, inform your doctor.

Take Meprate Tablet as advised by your doctor. The dose and duration depend on your medical condition. It can be taken with or without food, but try to take it at the same time every day to maintain consistent levels of Meprate Tablet in your body. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Ideally, you should try not to miss a dose of Meprate Tablet as missing a dose increases the chance of breakthrough vaginal bleeding or spotting (blood stain). However, if you miss a dose of Meprate Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed dose.

Country of origin

INDIA

Manufacturer/Marketer address

212/2, Hadapsar, Off Soli Poonawalla Road, Pune 411028 India.
Other Info - MEP0007

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