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  3. Mesacol Enema 60 ml

Mesacol Enema 60 ml, Pack of 1 Enema
Mesacol Enema 60 ml, Pack of 1 Enema
Mesacol Enema 60 ml, Pack of 1 Enema
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Mesacol Enema is treating ulcerative colitis and ulcerative proctitis. It contains Mesalamine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling). This lowers ulceration, bleeding, and stomach pain while preventing future illness flare-ups. Common side effects of Mesacol Enema are diarrhoea, stomach pain, headache or nausea.

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Synonym :

MESALAZINE

Composition :

MESALAMINE-4GM

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

RECTAL

Return Policy :

Not Returnable

Expires on or after :

About Mesacol Enema

Mesacol Enema is used to treat ulcerative colitis and ulcerative proctitis. Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). Ulcerative proctitis is a condition in which ulcerative colitis solely affects the rear channel (rectum).

Mesacol Enema contains Mesalamine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling).

Sometimes, you may experience diarrhoea, stomach pain, headache or nausea. Most of these side effects of Mesacol Enema do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Follow your doctor's instructions on the dosage and timing of this medication. Mesacol Enema is for rectal use only. It is advised to wash your hands before and after applying the medicament. Ensure the rectal area is clean and dry before application.

Inform your doctor if you are allergic to any components present in Mesacol Enema. Mesacol Enema should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before taking Mesacol Enema. Avoid taking Mesacol Enema if you have severe kidney failure. If you have stomach pain, cramps, severe headache, fever or rash, after taking Mesacol Enema, stop taking it immediately and consult a doctor.

Uses of Mesacol Enema

Mesacol Enema is used in the treatment of Ulcerative colitis and Ulcerative proctitis. The detailed uses of Mesacol Enema are as follows: <br/>

  • Management of Irritable Bowel Syndrome (IBS): Mesacol Enema helps manage IBS symptoms like bloating, gas, and abdominal discomfort.<br/>
  • Support for Ulcerative Colitis: Mesacol Enema supports ulcerative colitis management by reducing flare-ups and promoting gut health.<br/>

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions and use it as advised by the doctor. 
  • Before using, empty your bowels (if necessary) and wash your hands. Shake the bottle vigorously for at least 30 seconds. Remove the applicator's protective cap and hold the bottle by its top end. Lie on your left side, your left leg extended and your right leg bent. Insert the applicator (lubricant-coated) for easier entry into the rectum. Squeeze the bottle gently while holding it directed towards your navel. When the bottle is empty, remove the applicator from the rectum.
  • Allow the drug to spread throughout the lower section of the large intestine for at least 30 minutes by remaining in this posture.
  • Wash your hands before and after applying the medicament. Make sure that the rectal area is clean and dry before application.
  • For rectal use only.

Medicinal Benefits

  • Mesacol Enema contains Mesalamine, an anti-inflammatory drug used to treat ulcerative colitis and ulcerative proctitis.
  • This medicine helps reduce inflammation (redness and swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.
  • Mesacol Enema may also prevent further episodes of ulcerative colitis.

How Mesacol Enema Works

Mesacol Enema contains Mesalamine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling). This lowers ulceration, bleeding, and stomach pain while preventing future illness flare-ups.

Storage

• Store in a cool and dry place away from sunlight.• Keep Mesacol Enema out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Mesacol Enema

Please do not exceed the recommended dose, as it might cause an overdose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. This medicine may be harmful if swallowed. Seek emergency medical attention or call your doctor if you notice any unusual symptoms or if anyone has accidentally swallowed the medication.

Drug Warnings

  • Infor your doctor if oyu are allergic to it or any other components.
  • Mesacol Enema should be used with caution in the elderly.
  • Avoid taking Mesacol Enema if you have severe kidney failure.
  • Do not use Mesacol Enema if you are pregnant, planning to become pregnant, or breastfeeding without first consulting the doctor.
  • Mesacol Enema is recommended not to be used in populations with severe renal or hepatic impairment, so inform your doctor if you have severe renal or hepatic impairment.
  • Use Mesacol Enema in dose and duration as advised by a doctor only.
  • Mesacol Enema is for rectal use. Do not swallow it. In case of accidental swallowing, drink plenty of water and consult a doctor immediately.
  • $nam is not recommended for use in children.

Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help heal faster.
  • Opt for food and drinks high in Omega 3 fatty acids to relieve pain, swelling, and inflammation. Omega 3 rich acid-enriched foods include flaxseeds, walnut, soybean oil, salmon, and tuna if you prefer non-veg.
  • Eat more fibre-rich foods such as fruits and vegetables.
  • Eat smaller meals all day.
  • Drink small amounts of water throughout the day.
  • If you are intolerant to lactose, lower your intake of milk.
  • Avoid foods high in sugar, fat, and processed foods, as these, may cause inflammation.
  • Try to avoid alcohol as it can affect your stomach and intestine and also limits the absorption of the important nutrients required by your body.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS
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Alcohol

Caution

The interaction of alcohol with Mesacol Enema is unknown. However, avoid consuming alcohol while on treatment with this medicine.

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Pregnancy

Consult your doctor

Mesacol Enema should not be used in pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy.

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Breast Feeding

Consult your doctor

Mesacol Enema should not be used while breastfeeding unless necessary. So, inform your doctor if you are a nursing mother.

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Driving

Safe if prescribed

Mesacol Enema usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Inform your doctor before using Mesacol Enema if you have a history of liver disease. It should be used cautiously in patients with mild to moderately impaired liver function. It is not recommended for use in populations with severe liver impairment.

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Kidney

Caution

Inform your doctor before using Mesacol Enema if you have a history of kidney disease. It should be used cautiously in patients with mild to moderately impaired kidney function. It is not recommended for use in populations with severe kidney impairment.

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Children

Not applicable

Mesacol Enema is intended for adults. Not recommended for children.

Have a query?

FAQs

Mesacol Enema is used to treat ulcerative colitis and ulcerative proctitis.

Mesacol Enema contains Mesalamine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thus, it helps reduce inflammation (swelling) in the intestines and relieves stomach pain or bleeding symptoms.

Mesacol Enema may cause diarrhoea as a common side effect. However, if the condition persists or worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while using Mesacol Enema to prevent dehydration.

If you miss a dosage of mesalamine, take it as soon as you remember unless your next dose is approaching. In this situation, skip the missed dose and resume your regular schedule. Do not combine two doses to make up for a missed dosage.

You are recommended not to take Mesacol Enema with other medications without doctor&#039;s notice, especially immunosuppressant medications such as Azathioprine.

No, you are not recommended to stop using Mesacol Enema suddenly as it may cause recurring symptoms. Therefore, use Mesacol Enema for as long as your doctor has prescribed it, and if you experience any difficulty while using Mesacol Enema, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - MES0002

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 23, 2025 | 2:14 PM IST

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Reference

  1. https://ciplamed-library.com/content/mesalo-foam
  2. https://www.nhs.uk/medicines/mesalazine/
  3. https://www.medicines.org.uk/emc/files/pil.914.pdf

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