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  3. Metform 500 Tablet 20's

Metform 500 Tablet 20's, Pack of 20 TABLETS
Metform 500 Tablet 20's, Pack of 20 TABLETS
Metform 500 Tablet 20's, Pack of 20 TABLETS
Metform 500 Tablet 20's, Pack of 20 TABLETS
Metform 500 Tablet 20's, Pack of 20 TABLETS
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Synonym :

METFORMIN HYDROCHLORIDE

Composition :

METFORMIN-500MG

Manufacturer/Marketer :

Knoll Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Metform 500 Tablet

Metform 500 Tablet used to treat type 2 diabetes when diet and exercise alone have not been enough to control the blood glucose levels. Type 2 diabetes is a chronic condition that affects how the body processes glucose.

Metform 500 Tablet contains Metformin, which works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood. Thereby, Metform 500 Tablet helps control the amount of glucose (sugar) in the blood.

In some cases, Metform 500 Tablet may cause side effects like nausea, vomiting, diarrhoea, abdominal pain, and loss of appetite. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult the doctor.

Do not take Metform 500 Tablet if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Metform 500 Tablet is safe for use in children above 10 years if prescribed by the doctor. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Metform 500 Tablet

Metform 500 Tablet is used in the treatment of type 2 diabetes mellitus. The detailed uses of Metform 500 Tablet are as follows:
• Type 2 Diabetes Management: Metform 500 Tablet helps to control blood sugar levels by decreasing glucose production in the liver, improving insulin sensitivity, and enhancing glucose uptake by muscles.

Directions for Use

  • Take Metform 500 Tablet just after a meal or with a snack.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Metform 500 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Metform 500 Tablet belongs to a group of anti-diabetic medicines called biguanides, which help manage diabetes and achieve good control of blood sugar levels by delaying the absorption of sugar and increasing insulin sensitivity in the body.
  • It does not cause a sudden lowering of the blood glucose level or cause significant hypoglycaemia.
  • Unlike other anti-diabetic therapies like sulfonylureas or insulin, Metform 500 Tablet does not cause weight gain but may cause modest weight loss.
  • In the prediabetic condition, Metform 500 Tablet is the only recommended treatment available.
  • Metform 500 Tablet also helps to prevent serious complications of diabetes such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), loss of sensation in your hands and feet (diabetic neuropathy) or even loss of a foot.
  • It also helps to reduce your chances of having a heart attack or stroke.

How Metform 500 Tablet Works

Metform 500 Tablet contains Metformin, which works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood. Thereby, Metform 500 Tablet helps control the amount of glucose (sugar) in the blood.

Storage

Store in a cool and dry place away from sunlight
Side effects of Metform 500 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Metform 500 Tablet

Do not take more than the prescribed dose of Metform 500 Tablet as it may cause overdose leading to lactic acidosis (too much lactic acid in the body). The symptoms include stomach pain with muscle cramps, vomiting, reduced body temperature, difficulty in breathing, and a general feeling of not being well with severe tiredness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately, as lactic acidosis may lead to coma.

Drug Warnings

  • Do not take Metform 500 Tablet if you are allergic to any of its components or if you have severe kidney disease, diabetic ketoacidosis, or metabolic acidosis.
  • Inform your doctor if you have dehydration, infections, liver or kidney problems, uncontrolled diabetes, heart problems, or low levels of vitamin B12.
  • Consult your doctor if you are pregnant, plan to become pregnant or are breastfeeding.
  • Seek medical attention if you experience symptoms of lactic acidosis (vomiting, abdominal pain, muscle cramps, severe tiredness, difficulty breathing, and reduced body temperature and heartbeat) or dehydration (severe vomiting, diarrhoea, exposure to heat, fever or if you drink less fluid than normal).

Drug-Drug Interactions

verifiedApollotooltip
MetforminMetrizamide
Critical
MetforminIodamide
Critical

Drug-Drug Interactions

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MetforminMetrizamide
Critical
How does the drug interact with Metform 500 Tablet:
Co-administration of Metform 500 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Metform 500 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIodamide
Critical
How does the drug interact with Metform 500 Tablet:
Co-administration of Metform 500 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Metform 500 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopamidol
Critical
How does the drug interact with Metform 500 Tablet:
Co-administration of Iopamidol with Metform 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metform 500 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopromide
Critical
How does the drug interact with Metform 500 Tablet:
Co-administration of Iopromide with Metform 500 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Metform 500 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIomeprol
Critical
How does the drug interact with Metform 500 Tablet:
Co-administration of Iomeprol with Metform 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metform 500 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoversol
Critical
How does the drug interact with Metform 500 Tablet:
Co-administration of Ioversol with Metform 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metform 500 Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Metform 500 Tablet:
Co-administration of Iopentol with Metform 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metform 500 Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Metform 500 Tablet:
Co-administration of Iohexol with Metform 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metform 500 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Metform 500 Tablet:
Co-administration of Iopanoic acid with Metform 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metform 500 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Metform 500 Tablet:
Co-administration of Ioglycamic acid with Metform 500 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metform 500 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Invest at least 150 minutes of your week in moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise every week.
  • Losing weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replacing refined carbohydrate-containing foods with whole grain foods and increasing intake of fruits and veggies and other fibre-enriched foods. 
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you can use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil. 
  • Avoid taking too much stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes or meditation or yoga.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, cheese, etc.).
  • Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
  • Try to quit smoking and reduce your intake of carbohydrate-rich foods like potatoes, rice, mangoes, bread, sugar, etc.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Metform 500 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

It is advisable not to consume alcohol along with Metform 500 Tablet to avoid unpleasant side effects like lactic acidosis.

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Pregnancy

Caution

Consult the doctor if you are pregnant. This medicine should be used during pregnancy only if clearly needed.

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Breast Feeding

Caution

Metform 500 Tablet is not recommended if you are breastfeeding or if you are planning to breastfeed your baby.

bannner image

Driving

Safe if prescribed

Metform 500 Tablet may not affect your ability to drive. However, drive or operate machinery only if you are alert.

bannner image

Liver

Caution

Metform 500 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Metform 500 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor depending on your renal function. Metform 500 Tablet is not recommended in severe kidney disease. Regular monitoring of kidney function tests is therefore important if you're taking Metform 500 Tablet .

bannner image

Children

Caution

Metform 500 Tablet is not recommended for children below 10 years of age. For children above 10 years, the dose will be recommended by the doctor.

Have a query?

FAQs

Metform 500 Tablet is used to treat type 2 diabetes mellitus.

Metform 500 Tablet lowers blood glucose levels by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver.

Metform 500 Tablet is associated with either modest weight loss or stable body weight. However, if you experience excessive weight loss while on treatment with Metform 500 Tablet , inform your doctor without any delay. There is a possibility that your dosage needs to be adjusted.

Yes. If you are taking Insulin regularly, you need to consult a doctor before taking Metform 500 Tablet .

Try to take your medicine at the scheduled time, and do not skip your doses. If you forget to take Metform 500 Tablet , do not take a double dose to make up for your forgotten dose. Taking an overdose might cause your sugar level to fall rapidly. Try to take the next dose at the usual time.

Do not take excessive alcohol while taking Metform 500 Tablet , as this may increase the risk of a life-threatening condition called lactic acidosis (too much lactic acid in the body), which causes symptoms like dizziness, drowsiness, muscle pain, fast, shallow breathing, etc.

Contact your doctor before having an X-ray or scan which involves the injection of contrast materials that contain iodine into your bloodstream, as it may affect your kidney function.

Your doctor will decide when you must stop and when to restart your treatment with Metform 500 Tablet before and after the surgery.

No. Metform 500 Tablet is only prescribed for the treatment of type 2 diabetes, also called non-insulin-dependent diabetes. It is not indicated for type 1 diabetes.

Metform 500 Tablet should be swallowed as a whole with water. Taking it with or after a meal helps prevent side effects affecting digestion.

Metform 500 Tablet helps to lower your blood glucose to as normal a level as possible. It increases your body's response to insulin and decreases the amount of glucose absorbed from your food and the amount of glucose made by your liver.

Metform 500 Tablet may not make you sleepy. Consult the doctor if you experience sleepiness, as it could be a sign of ketoacidosis.

Symptoms of lactic acidosis include abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness. Consult the doctor if you experience these symptoms.

Metform 500 Tablet can be used during pregnancy only if prescribed by the doctor. Please consult the doctor if you are pregnant, planning for pregnancy or think you may be pregnant.

Metform 500 Tablet may cause side effects like nausea, vomiting, diarrhoea, abdominal pain, and loss of appetite. Most of these side effects do not require medical attention and resolve gradually overtime. However, if the side effects persist or worsen, consult the doctor.

Store Metform 500 Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.

Country of origin

INDIA

Manufacturer/Marketer address

M-17, Pharma Tower, Basement & Ground Floor, Badli Industrial Area, New Delhi 110 042
Other Info - MET0599

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 16, 2025 | 2:21 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.10759.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
  3. https://medlineplus.gov/druginfo/meds/a696005.html
  4. https://www.drugs.com/metformin.html

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