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compositionComposition:METHYLERGOMETRINE-0.125MG
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Prescription Medicine
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Methergin Tablet is used to prevent and control postpartum haemorrhage. This medicine contains methylergometrine, which increases the uterus's smooth muscle contractions and thereby controls bleeding after delivery. Some of the side effects include seizures and/or headache, nausea, and vomiting.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METHYLERGOMETRINE-0.125MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Methergin Tablet

Methergin Tablet is a prescription medicine used to prevent and treat excessive bleeding that can occur after childbirth or a miscarriage. It works by making the muscles of the womb contract, which reduces blood loss and helps the body recover safely. This medicine plays an important role in managing postpartum care under medical supervision.

Methergin Tablet is a prescription medicine used to prevent and treat excessive bleeding that can occur after childbirth or a miscarriage. It works by making the muscles of the womb contract, which reduces blood loss and helps the body recover safely. This medicine plays an important role in managing postpartum care under medical supervision.

Your doctor will determine how often you should take this medicine, and it is crucial to take it exactly as prescribed without skipping any doses. You can take this tablet with or without food, but taking it at the same times each day helps maintain a steady level of the medicine in your body. Along with taking this medicine, resting plenty, staying hydrated, and eating a well-balanced diet rich in iron can support your body's recovery process.

While taking this medicine, you might experience mild side effects like nausea, vomiting, or mild headaches. However, if you notice serious symptoms such as severe chest pain, sudden numbness in your fingers or toes, or a very severe headache with blurred vision, you must contact your doctor immediately.

Talk to your doctor or pharmacist if you have a history of high blood pressure, heart disease, kidney issues, or liver damage before starting this medication. Do not take this medicine if you have uncontrolled high blood pressure, toxemia of pregnancy, or if you are currently pregnant and have not yet delivered your baby.

Certain medicines, grapefruit juice, alcohol, and smoking can interact with this medicine, potentially causing dangerous increases in blood pressure or poor blood flow to your extremities. If you are breastfeeding, elderly, or have other medical concerns, consult your doctor to ensure this medicine is safe for your specific situation.

Uses of Methergin Tablet

Your doctor may prescribe Methergin Tablet to help manage the following conditions:

  • Postpartum bleeding: It helps prevent and control heavy bleeding from the uterus after delivering a baby by promoting strong uterine contractions.
  • Post-abortal bleeding: It helps control excessive bleeding that may occur after a miscarriage or a medical termination of pregnancy.

Key Benefits

When used as directed as part of your treatment plan, Methergin Tablet may provide the following benefits:

  • Helps control excessive bleeding: Reduces heavy bleeding after childbirth or a miscarriage.
  • Supports normal uterine recovery: Helps the uterus contract and return to its usual size after delivery or a miscarriage.
  • Supports recovery after childbirth or miscarriage: By controlling excessive bleeding, it helps your body recover more effectively.
Side effects of Methergin Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Methergin Tablet can be taken with or without food.
  • Your healthcare provider will decide the correct dosage and frequency based on your condition.
  • Take it exactly as prescribed, usually with a full glass of water.
  • Do not crush, chew, or break the tablet. Swallow it whole as directed.
  • Do not change the dose or stop taking the medication without first consulting your doctor.

How Methergin Tablet Works

Methergin Tablet contains methylergometrine. It works by directly stimulating the smooth muscles of the womb (uterus). It increases the strength, frequency, and duration of uterine contractions. These contractions squeeze the blood vessels that flow into the uterus, which effectively clots and stops the bleeding. By restoring tone to a relaxed womb, it helps return the organ to its normal size while preventing life-threatening blood loss.
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Alcohol

Caution

It is not known if alcohol affects Methergin Tablet . Please consult your doctor.

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Pregnancy

Unsafe

Methergin Tablet is not recommended for use during pregnancy.

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Breast Feeding

Caution

Methergin Tablet passes into breastmilk. Avoid breastfeeding during treatment with Methergin Tablet and for 12 hours after the last dose. Please consult your doctor if you have any concerns.

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Driving

Caution

It is not known if Methergin Tablet affects your ability to drive.

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Liver

Caution

Caution should be exercised while using Methergin Tablet in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Caution should be exercised while using Methergin Tablet in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Methergin Tablet is not recommended for children as safety and effectiveness have not been established.

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Heart

Caution

Methergin Tablet may not be safe for patients with heart conditions. Please inform your doctor about any heart-related issues before using Methergin Tablet .

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Geriatrics

Caution

Methergin Tablet should be used with caution in elderly patients, as they may be more susceptible to side effects. Dose adjustments may be necessary. Always consult a healthcare professional before use.

What if I have taken an overdose of Methergin Tablet

If you suspect an overdose, seek immediate medical attention. Symptoms of an overdose can include severe headache, numbness in extremities, difficulty breathing, or seizures.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of fluids, such as water or clear broths, to help your body recover from blood loss and maintain healthy circulation.
  • Eat iron-rich foods: Incorporate spinach, red meat, beans, and fortified cereals into your meals to help rebuild red blood cells and combat fatigue after bleeding.
  • Avoid smoking and tobacco products: Nicotine constricts your blood vessels, which can dangerously compound the narrowing effects of this medicine.
  • Prioritise physical rest: Avoid heavy lifting and strenuous activities while your body is healing to prevent triggering further uterine bleeding.

Health Queries

I am experiencing excessive bleeding 35 days after my C-section delivery. What medication or treatment should I take to manage this?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Experiencing heavy bleeding 35 days after a C-section requires prompt medical evaluation. Please contact your obstetrician immediately rather than trying to self-medicate, as the correct treatment depends on the exact cause (such as retained tissue or a delayed recovery of the uterus). Your doctor may perform an ultrasound and might prescribe medications like uterotonics (such as methylergonovine) to help your uterus contract, or antibiotics if an infection is present. If you experience fever, severe abdominal pain, or pass very large clots, please seek emergency care. This is a highly treatable issue, so please reach out to your healthcare provider for safe, personalized guidance.
health query

Have a query?

How Soon It Starts Working

The time required for Methergin Tablet to start to work: Methergin Tablet ideally shows its action within 5 to 10 minutes after administration. The time for which the effects of Methergin Tablet last: The effect of Methergin Tablet lasts for 3 hours.

What if you forget to take Methergin Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store the tablets at room temperature between 20°C and 25°C (68°F and 77°F).

Drug Warnings

  • Take as prescribed: Take Methergin Tablet exactly as your doctor prescribes. Do not take more than the recommended dose or use it for longer than advised.
  • Pregnancy: This medicine is intended for use after childbirth or a miscarriage. Do not take it during pregnancy unless your doctor specifically advises you to do so.
  • Breastfeeding: If you are breastfeeding, your doctor may advise you not to breastfeed for at least 12 hours after your last dose. Follow your doctor's instructions and discard any breast milk expressed during this time.
  • Tell your doctor about your health conditions: Before taking Methergin Tablet , tell your doctor if you have high blood pressure, heart disease, liver disease, or kidney disease.
  • Avoid grapefruit: Do not eat grapefruit or drink grapefruit juice during treatment, as it may increase the chance of side effects.
  • Tell your doctor about all your medicines: This includes medicines for migraine, antibiotics, antifungal medicines, and any other prescription, over-the-counter, or herbal medicines.
  • Consult your doctor right away if you feel unwell: Seek medical advice if you develop severe chest pain, severe headache, changes in vision, numbness or pain in your fingers or toes, or signs of an allergic reaction.

Drug-Drug Interactions

verifiedApollotooltip
  • Certain antibiotics and antifungal medicines: Medicines such as clarithromycin, erythromycin, and ketoconazole may increase the amount of Methergin Tablet in your body, which can increase the risk of side effects.
  • Migraine medicines and other ergot medicines: Medicines such as triptans or other medicines containing ergot alkaloids should not usually be taken with Methergin Tablet because they may increase the risk of blood vessel problems.
  • Medicines for high blood pressure or heart conditions: These medicines may affect how Methergin Tablet works or increase the chance of side effects. Your doctor may monitor your treatment more closely if you need to take them together.
MethylergometrineKetoconazole
Critical
MethylergometrineGlyceryl trinitrate
Critical

Drug-Drug Interactions

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MethylergometrineKetoconazole
Critical
How does the drug interact with Methergin Tablet:
Using Ketoconazole with Methergin Tablet can increase the concentration of Methergin Tablet, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Methergin Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineGlyceryl trinitrate
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Methergin Tablet with Glyceryl trinitrate can increase the levels and side effects of Methergin Tablet.

How to manage the interaction:
Taking Methergin Tablet with Glyceryl trinitrate is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
MethylergometrineClarithromycin
Critical
How does the drug interact with Methergin Tablet:
When Methergin Tablet is taken with Clarithromycin, the amount of Methergin Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clarithromycin with Methergin Tablet is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
MethylergometrineRitonavir
Critical
How does the drug interact with Methergin Tablet:
Taking Methergin Tablet with Ritonavir can significantly increase the blood levels and effects of Methergin Tablet.

How to manage the interaction:
Taking Methergin Tablet with Ritonavir is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.
MethylergometrineItraconazole
Critical
How does the drug interact with Methergin Tablet:
Co-administration of Methergin Tablet and Itraconazole may increase the blood levels of Methergin Tablet.

How to manage the interaction:
Methergin Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
MethylergometrineSumatriptan
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Sumatriptan with Methergin Tablet can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Sumatriptan with Methergin Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MethylergometrineVoriconazole
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Methergin Tablet with Voriconazole may increase the blood level of Methergin Tablet.

How to manage the interaction:
Although Methergin Tablet with Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineEphedrine
Severe
How does the drug interact with Methergin Tablet:
Taking Ephedrine with Methergin Tablet may lead to an increase in the risk of high blood pressure.

How to manage the interaction:
Although taking Ephedrine with Methergin Tablet may lead to an interaction, it can be taken if prescribed by the doctor. It is advised to maintain your blood pressure. Do not discontinue any medications without a doctor's advice.
MethylergometrinePhenylephrine
Severe
How does the drug interact with Methergin Tablet:
Taking Phenylephrine with Methergin Tablet can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Phenylephrine with Methergin Tablet can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: Grapefruit may increase the amount of Methergin Tablet in your body, which can increase the chance of side effects.
  • Alcohol: Alcohol may increase some side effects, such as dizziness. Ask your doctor whether it is suitable for you to drink alcohol during treatment.
METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of Methergin Tablet with Grapefruit and Grapefruit may lead to an increase in the effectiveness of Methergin Tablet. Avoid or limit grapefruit and grapefruit juice consumption with Methergin Tablet. This can increase the risk or severity of side effects.

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Methergin Tablet is used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.
Methergin Tablet works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.
Methergin Tablet is not recommended for use in people with high blood pressure. Consult your doctor if you have hypertension.
Methergin Tablet may cause nausea or vomiting as a side effect. It is not necessary for everyone taking Methergin Tablet to experience this side effect. However, if the condition persists or worsens, consult your doctor.
Methergin Tablet may be indicated in the management of uterine atony. Uterine atony refers to a weak and soft uterus after childbirth.
Yes, Methergin Tablet may cause decreased milk production if taken by lactating mothers after childbirth. It is recommended to avoid breastfeeding while taking Methergin Tablet for at least 12 hours after your last dose. Consult the doctor if you have any concerns.
No, Methergin Tablet should not be used to stop menstrual bleeding as it is used to manage and prevent excessive bleeding after childbirth (postpartum haemorrhage).
Methergin Tablet should be taken with or without food as advised by the doctor based on your medical condition.
You should not take Methergin Tablet if you are allergic to any of its ingredients. It should not be taken by individuals with high blood pressure (hypertension), or toxaemia (an abnormal condition associated with the presence of toxic substances in the bloodstream) during pregnancy.
No, breastfeeding should be avoided during treatment with Methergin Tablet and for at least 12 hours after the final dose. Consult the doctor if you have any concerns.
Yes, Methergin Tablet may cause an increase in blood pressure as a common side effect. Consult the doctor before taking Methergin Tablet if you have high blood pressure.
Patients with heart disease may have an increased risk of myocardial ischemia and infarction due to methylergonovine-induced vasospasm. Consult the doctor if you have any heart problems.
The side effects of Methergin Tablet include nausea, vomiting, headache, and hypertension (increased blood pressure) associated with seizures. Consult the doctor if any of these symptoms persist or worsen.
No, you should not take this medicine while you are pregnant. It is designed to cause uterine contractions to manage bleeding after childbirth or miscarriage, and taking it during pregnancy can harm the unborn baby. Talk to your doctor if you have any questions.
Yes, this medicine can cause your blood pressure to rise, sometimes significantly. If you have a history of high blood pressure, make sure to discuss this with your healthcare provider. Talk to your doctor right away if you experience a severe headache or blurred vision while taking this medicine.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can increase side effects like dizziness and drowsiness and may interfere with your body's recovery process. Talk to your doctor for personalised advice.
The duration of treatment depends entirely on your specific condition and how well your bleeding is controlled. Usually, it is prescribed for only a few days after delivery or miscarriage. Always finish the exact course prescribed by your healthcare provider, and talk to your doctor if you have concerns.
Coldness, numbness, or tingling in your extremities can be a sign of reduced blood flow caused by blood vessel narrowing. This is a serious side effect that requires immediate attention. Stop taking the medicine and talk to your doctor right away.
No, you should avoid smoking or using nicotine products while taking this medicine. Nicotine constricts blood vessels, which can worsen the vessel-narrowing effects of this medicine and lead to severe circulation problems. Talk to your doctor if you need support quitting.

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Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - MET0067
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