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compositionComposition:METHIMAZOLE-5MG
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Prescription Medicine
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Methimercazole 5 Tablet is used to treat an overactive thyroid (hyperthyroidism) and Graves disease. It contains methimazole, which works by reducing the excessive production of thyroid hormones. In some cases, this medicine may cause side effects such as headache, stomach upset, nausea, vomiting, mild skin rash or itching. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METHIMAZOLE-5MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Methimercazole 5 Tablet

Methimercazole 5 Tablet is an oral prescription medication used to treat hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. It is also commonly prescribed to manage symptoms before thyroid surgery or radioactive iodine treatment. By regulating thyroid activity, Methimercazole 5 Tablet helps bring your body's metabolism back into a healthy balance.

To get the best results, it is important to take Methimercazole 5 Tablet consistently at the same time every day. You can take this tablet with or without food, but choosing one way and sticking to it helps keep the medicine levels steady in your body. Along with taking your medicine, reducing your intake of iodine-rich foods can support your treatment.

While taking Methimercazole 5 Tablet , some people may experience mild side effects like upset stomach, joint pain, or minor skin rashes. However, you must contact your doctor immediately if you develop serious symptoms such as a sore throat, fever, unusual bruising, or yellowing of your skin and eyes.

Do not take Methimercazole 5 Tablet if you have had a severe allergic reaction to antithyroid medications in the past. Before starting Methimercazole 5 Tablet , tell your doctor if you have liver disease, blood disorders, or a compromised immune system.

Methimercazole 5 Tablet can interact with blood thinners and certain heart medications, which may require your doctor to adjust your therapy. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider, as special precautions are needed to protect your baby.

Uses of Methimercazole 5 Tablet

Methimercazole 5 Tablet used in the treatment of Hyperthyroidism and Graves' disease. The detailed uses of Methimercazole 5 Tablet are as follows:

  • Hyperthyroidism: Methimercazole 5 Tablet helps control an overactive thyroid gland by reducing the excess production of thyroid hormones.
  • Graves' disease: It manages the symptoms of this autoimmune disorder by stopping the thyroid from overproducing hormones.
  • Pre-surgery preparation: Taking Methimercazole 5 Tablet before a thyroidectomy (surgical removal of the thyroid) helps stabilize thyroid levels, making the procedure safer.
  • Radioactive iodine therapy preparation: It helps control thyroid hormone levels before or sometimes after undergoing radioactive iodine treatment.

Key Benefits

Methimercazole 5 Tablet helps manage an overactive thyroid by reducing the production of excess thyroid hormones. As thyroid hormone levels return to a healthier range, it helps improve symptoms and supports overall well-being. Benefits may include:

  • Helps reduce symptoms such as rapid heartbeat, hand tremors, excessive sweating, and heat intolerance.
  • Supports the maintenance of healthy thyroid hormone levels.
  • Helps relieve anxiety, irritability, and restlessness associated with hyperthyroidism.
  • Improves muscle strength and helps reduce fatigue.
  • Helps prevent unintended weight loss caused by an overactive thyroid.
  • Supports long-term control of hyperthyroidism and improves overall quality of life.

Directions for Use

  • Methimercazole 5 Tablet can be taken with or without food, as advised by your doctor.
  • It is usually taken 3 times daily or as prescribed by your doctor.
  • Swallow Methimercazole 5 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Methimercazole 5 Tablet Works

Methimercazole 5 Tablet contains Methimazole, which helps reduce the production of excess thyroid hormones by blocking their formation in the thyroid gland. This helps control symptoms of an overactive thyroid, such as rapid heartbeat, nervousness, sweating, weight loss, and tremors. Since it does not affect hormones already present in the body, it may take several weeks to show its full effect.
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Alcohol

Consult your doctor

Please consult your doctor before using Methimercazole 5 Tablet regarding the intake of alcohol during treatment. However, it is advised to limit alcohol consumption until your course is finished.

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Pregnancy

Consult your doctor

Methimercazole 5 Tablet is not recommended for use during the first trimester or three months of pregnancy since it can cause harmful effects on the foetus. It is advised to consult your doctor if you plan to conceive or are already pregnant before starting Methimercazole 5 Tablet .

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Breast Feeding

Caution

Methimercazole 5 Tablet passes into the breast milk when used by a lactating mother. Please consult your doctor before taking Methimercazole 5 Tablet if you are breastfeeding. Caution is recommended.

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Driving

Caution

Methimercazole 5 Tablet may make you feel dizzy and sleepy, which could affect your ability to drive or operate machines. Please do not drive or operate machines until you feel better.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Methimercazole 5 Tablet . Regular monitoring of liver function tests is advised during course.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Methimercazole 5 Tablet .

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Children

Caution

Your doctor will decide the dose and duration based on your child’s age and medical condition.

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Heart

Caution

Methimercazole 5 Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Methimercazole 5 Tablet .

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Geriatrics

Caution

Methimercazole 5 Tablet should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform a healthcare professional before use.

What if I have taken an overdose of Methimercazole 5 Tablet

If you or someone else takes too much Methimercazole 5 Tablet , seek immediate medical attention or contact a poison control center. Symptoms of an overdose may include skin swelling, fever, joint pain, or extreme fatigue.

Diet & Lifestyle Advise

  • Limit iodine-rich foods: High amounts of iodine from foods like kelp, seaweed, iodized salt, and certain seafood can interfere with your treatment. Talk to your doctor before using iodine-containing supplements.
  • Avoid heavy caffeine intake: Since hyperthyroidism can cause a racing heart and anxiety, limiting coffee, energy drinks, and sodas can help manage these symptoms.
  • Eat calcium-rich foods: An overactive thyroid can weaken your bones over time. Incorporating calcium and vitamin D into your diet supports bone health.
  • Get regular, low-impact exercise: Gentle physical activities like walking or swimming can help strengthen muscles and maintain bone density without overworking your heart.

Health Queries

My daughter has a small swelling under her neck, and the doctor advised a scan, FNAC, and thyroid blood tests. Based on these reports, what are the potential diagnoses, and what medications or treatment options are recommended?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

A small neck swelling is common and usually highly treatable. The tests ordered will pinpoint the exact cause. Potential diagnoses include a benign thyroid nodule, a fluid-filled cyst, thyroiditis (inflammation), or a reactive lymph node from a mild infection. Treatment depends entirely on the results: an underactive thyroid is managed with levothyroxine; an overactive thyroid may require methimazole; and infections are treated with antibiotics. Many benign swellings require no treatment, just monitoring. These tests are routine steps to ensure accurate care, so please try not to worry. Once reports are ready, your doctor will guide you on the best, simple path forward.

I have been experiencing a severe headache for 3 months, along with hyperthyroidism and a PTH level of 455. What medication or treatment is recommended for this condition?

Vikas Singh

Vikas Singh

M Pharmacy

Your symptoms and high parathyroid hormone (PTH) level of 455 suggest hyperparathyroidism, which elevates calcium levels and commonly causes severe headaches. This is occurring alongside your hyperthyroidism. The definitive treatment for hyperparathyroidism is usually a highly successful, minor surgery to remove the affected parathyroid gland. For hyperthyroidism, medications like methimazole can help regulate your thyroid. I highly recommend consulting an endocrinologist. They will check your calcium levels and perform imaging (like an ultrasound) to tailor your treatment. Rest assured, these conditions are highly treatable, and correcting your hormone levels should resolve your headaches.
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How Soon It Starts Working

  • The time required for Methimercazole 5 Tablet to start to work: Methimercazole 5 Tablet ideally shows its action within 12 to 18 hours after administration.
  • The time for which the effects of Methimercazole 5 Tablet last: The effect of Methimercazole 5 Tablet lasts for 36 to 72 hours.

What if you forget to take Methimercazole 5 Tablet

Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular routine. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Monitor for signs of infection: A sudden fever or sore throat can be a sign of a rare but serious drop in white blood cells. Stop taking the medicine and contact your doctor immediately if this happens.
  • Watch for liver warning signs: Contact your doctor right away if you notice dark urine, pale stools, or yellowing of your skin or eyes.
  • Be consistent: Taking Methimercazole 5 Tablet at the exact same time every day helps maintain stable thyroid levels and improves the success of your treatment.
  • Inform all healthcare providers: Always tell your dentist, surgeon, or any other doctor that you are taking Methimercazole 5 Tablet before undergoing any medical procedures.
  • Keep up with blood work: Frequent thyroid and liver function blood tests are necessary to ensure the medication is working safely. Do not skip these appointments.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (e.g., warfarin): Taking these medicines alongside Methimercazole 5 Tablet may affect how blood thinners work, increasing the risk of bleeding or reducing their effectiveness. Your doctor may monitor your treatment more closely.
  • Beta-blockers (e.g., metoprolol, propranolol): As thyroid hormone levels return to normal during treatment with Methimercazole 5 Tablet , your response to beta-blockers may change, and dose adjustments may be needed.
  • Heart medicine (e.g., digoxin): Treatment with Methimercazole 5 Tablet may change how your body responds to digoxin as hyperthyroidism improves, and your doctor may need to adjust the dose.
MethimazoleClozapine
Severe
MethimazoleTeriflunomide
Severe

Drug-Drug Interactions

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MethimazoleClozapine
Severe
How does the drug interact with Methimercazole 5 Tablet:
When Clozapine is taken with Methimercazole 5 Tablet, the effects of Clozapine increases.

How to manage the interaction:
There may be a possibility of interaction between Methimercazole 5 Tablet and Clozapine, but it can be taken if prescribed by a doctor. If you have any of these symptoms - feeling weak, having a sore throat, fever, mouth sores, feeling tired or having flu-like symptoms, contact a doctor right away. Do not stop using any medications without a doctor's advice.
MethimazoleTeriflunomide
Severe
How does the drug interact with Methimercazole 5 Tablet:
The combined use of Methimercazole 5 Tablet with Teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Taking Methimercazole 5 Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, liver damage, or bleeding. Do not discontinue any medications without consulting a doctor.
MethimazolePropylthiouracil
Severe
How does the drug interact with Methimercazole 5 Tablet:
Taking Propylthiouracil with Methimercazole 5 Tablet can increase the risk of side effects.

How to manage the interaction:
Co-administration of Propylthiouracil with Methimercazole 5 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MethimazoleLomitapide
Severe
How does the drug interact with Methimercazole 5 Tablet:
Taking Lomitapide and Methimercazole 5 Tablet together can increase the risk of liver problems.

How to manage the interaction:
Although taking Methimercazole 5 Tablet and Lomitapide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, contact a doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, bleeding, dark urine, or liver damage. Do not stop using any medications without a doctor's advice.
MethimazoleMipomersen
Severe
How does the drug interact with Methimercazole 5 Tablet:
The combined use of Mipomersen and Methimercazole 5 Tablet together can increase the liver problems.

How to manage the interaction:
Although there is a possible interaction between Methimercazole 5 Tablet and Mipomersen, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, contact a doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, bleeding, pain, dark urine, or liver damage. Do not stop using any medications without talking to a doctor.
MethimazoleDeferiprone
Severe
How does the drug interact with Methimercazole 5 Tablet:
Taking Methimercazole 5 Tablet with Deferiprone may increase the risk of severe infections.

How to manage the interaction:
Taking Methimercazole 5 Tablet with Deferiprone together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms - like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination - contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MethimazoleFluphenazine
Severe
How does the drug interact with Methimercazole 5 Tablet:
Co-administration of Fluphenazine and Methimercazole 5 Tablet together can cause the risk of neutropenia leading to serious infections.

How to manage the interaction:
Although there is a possible interaction between Methimercazole 5 Tablet and Fluphenazine, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - fever, chills, body aches, sore throat, coughing, breathing difficulties, mouth ulcers, or flu-like symptoms - contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Iodine-rich foods and supplements (e.g., seaweed, kelp, iodine supplements): Consuming large amounts of iodine may reduce the effectiveness of Methimercazole 5 Tablet by providing the thyroid gland with more iodine to produce thyroid hormones.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Methimercazole 5 Tablet is used to treat hyperthyroidism (an overactive thyroid) and Graves disease (an autoimmune disorder).
Methimercazole 5 Tablet consists of Methimazole, an anti-thyroid agent. It treats overactive thyroid (hyperthyroidism) and Graves disease by inhibiting the synthesis of thyroid hormones by the thyroid gland. Thus, Methimercazole 5 Tablet effectively helps in treating hyperthyroidism and relieving its symptoms.
Methimercazole 5 Tablet should be used with caution and only under doctor's supervision if you have a medical history of liver or kidney diseases, congenital disorders (birth defects), hypothyroidism (low levels of thyroid hormones), blood disorders like agranulocytosis (lowered white blood cell count) and thrombocytopenia (low levels of platelets) and pancreatitis (inflammation of the pancreas, an organ behind the stomach).
Sometimes, Methimercazole 5 Tablet may cause hypoprothrombinemia (deficiency of the blood-clotting substance, prothrombin) and lead to bleeding. Hence, your doctor may advise a test for prothrombin time before surgery while undergoing treatment with Methimercazole 5 Tablet . Please seek medical advice for more information.
It is advised to regularly monitor your thyroid hormone levels with thyroid function tests while using Methimercazole 5 Tablet . If there is clinical evidence of rising serum thyroid levels, your doctor may lower the dose of Methimercazole 5 Tablet .
If you missed a dose, take Methimercazole 5 Tablet as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
You may begin to feel better within 2 to 4 weeks of starting the medication, but it can take several months to fully restore your thyroid levels to normal. Talk to your doctor if you do not notice any improvement after a few weeks.
Methimercazole 5 Tablet is generally not recommended during the first trimester of pregnancy due to potential risks to the developing baby, though it may be used later in pregnancy if necessary. Talk to your doctor about the safest options for managing your thyroid during pregnancy.
Yes, you will need frequent blood tests to monitor your thyroid hormone levels, liver enzymes, and blood cell counts. These tests help your doctor adjust your dose and ensure the medicine is working safely. Talk to your doctor about your testing schedule.
As Methimercazole 5 Tablet successfully slows down your overactive metabolism, your body may return to its normal weight, which some patients experience as weight gain. This is typically a sign that your thyroid is recovering. Talk to your doctor or a dietitian if you have concerns about weight changes.

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Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - MET1782
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