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Methylene Blue Injection is used to treat a condition called methemoglobinemia. Besides this, it can be used to treat vasodilatory shock unresponsive to conventional therapy. It contains Methylene Blue, which works by converting methemoglobin to a more efficient type of haemoglobin to better carry oxygen throughout the body. Common side effects of this medication are mild to moderate pain at the site of injection, pain in your arms or legs, blue or green urine, altered sense of taste, headache, dizziness, sweating, skin discolouration, nausea, and feeling warm.
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About Methylene Blue Injection
Methylene Blue Injection is used to treat a condition called methemoglobinemia. Besides this, it can be used to treat vasodilatory shock unresponsive to conventional therapy. Methemoglobinemia is a condition that occurs when the blood cannot deliver oxygen where it is needed in the body. Vasodilatory shock is a medical emergency in which your body cannot get enough blood to your heart, brain, and kidneys.
Methylene Blue Injection contains Methylene Blue. Methylene blue works by converting methemoglobin to a more efficient type of haemoglobin to better carry oxygen throughout the body.
A qualified healthcare professional will administer Methylene Blue Injection. You may experience mild to moderate pain at the site of injection, pain in your arms or legs, blue or green urine, altered sense of taste, headache, dizziness, sweating, skin discolouration, nausea, and feeling warm. Most of these side effects of Methylene Blue Injection do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
If you have a glucose-6-phosphate dehydrogenase (G6PD) deficiency, you should avoid using methylene blue. Many medicines, particularly antidepressants, can interact with methylene blue. So, before taking the Methylene Blue Injection, inform your doctor about all of your medical issues, sensitivities, and drugs. Also, let your doctor know if you are pregnant, planning to become pregnant, or are breastfeeding.
Uses of Methylene Blue Injection
Methylene Blue Injection is used in the treatment of Methemoglobinemia and Vasodilatory shock. The detailed uses of Methylene Blue Injection are as follows:
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Directions for Use
Medicinal Benefits
Methylene Blue Injection contains Methylene Blue, which belongs to the class of monoamine oxidase inhibitors. It is used to treat a condition called methemoglobinemia. Methylene blue converts methemoglobin into a more efficient type of haemoglobin to better carry oxygen throughout the body.
How Methylene Blue Injection Works
Storage
What if I have taken an overdose of Methylene Blue Injection
Drug Warnings
It is recommended not to use it if you are allergic to methylene blue or other ingredients. Methylene blue should not be used to treat methemoglobinemia in people with glucose-6-phosphate deficiencies (G-6-PD). When methylene blue was delivered intravenously to patients who were concurrently taking other medications having serotonin reuptake inhibitor characteristics, serotonin toxicity/serotonin syndrome was reported. If drugs with serotonin reuptake inhibition capabilities are being used, they must be stopped before using methylene blue injectables to allow for a washout time of at least 4 - 5 half-lives. So, before taking the Methylene Blue Injection, let your doctor know about all your medical conditions, sensitivities, and all medications you are using.
Drug-Drug Interactions
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Diet & Lifestyle Advise
Habit Forming
Therapeutic Class
Alcohol
Caution
It is not known whether Methylene Blue Injection interacts with alcohol. However, as a precautionary measure, it is advisable not to take or limit alcohol.
Pregnancy
Caution
Inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Methylene Blue Injection.
Breast Feeding
Caution
Let your doctor know if you are a nursing mother before taking Methylene Blue Injection; your doctor may suggest stopping breastfeeding for a certain period.
Driving
Safe if prescribed
Methylene Blue Injection usually does not affect your ability to drive or operate machinery.
Liver
Caution
Limited information was available about using Methylene Blue Injection in patients with liver disease. Inform your doctor before receiving Methylene Blue Injection if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Caution
Use with caution in patients with kidney failure, as methylene blue is primarily excreted through the kidneys. Inform your doctor before receiving Methylene Blue Injection if you have a history of kidney diseases. Your doctor will prescribe only if the benefits outweigh the risks.
Children
Safe if prescribed
Please consult your doctor. Your doctor will prescribe this medicine based on your child's condition.
Heart
Methylene Blue Injection may be used in individuals with heart conditions, but its cardiac effects depend on timing and underlying disease. Thorough cardiovascular evaluation is essential to ensure safe and appropriate administration.
Geriatrics
Caution
Methylene Blue Injection can be administered to geriatric patients, but careful dosing and monitoring are essential due to age-related changes in renal and hepatic function. Lower doses are typically recommended, and clinicians should assess for potential drug interactions and adverse effects such as serotonin syndrome or hypotension.
Methylene Blue Injection is used to treat a condition called methemoglobinemia. Besides this, it can be used to treat vasodilatory shock unresponsive to conventional therapy.
Methylene Blue Injection contains Methylene Blue. Methylene blue converts methemoglobin into a more efficient type of haemoglobin to better carry oxygen throughout the body. Thus, it efficiently treats a condition called methemoglobinemia.
Injection site reactions, pain in your arms or legs, blue or green urine, altered sense of taste, headache, dizziness, sweating, skin discolouration, nausea, and feeling warm are the common side effects of Methylene Blue Injection.
If you are currently taking anti-depressant medications such as escitalopram, notify your doctor before receiving methylene blue. Combining these medications can increase the risk of an uncommon but deadly disease known as serotonin syndrome, which can cause symptoms such as confusion, hallucination, seizure, dramatic fluctuations in blood pressure, rapid heart rate, and fever.
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