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  3. Metpure AM 2.5 Tablet 10's

Prescription drug
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Metpure AM 2.5 Tablet 10's, Pack of 10 TabletS
Metpure AM 2.5 Tablet 10's, Pack of 10 TabletS
Metpure AM 2.5 Tablet 10's, Pack of 10 TabletS
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Extra 15% Off with Bank Offers

Synonym :

S AMLODIPINE+S METOPROLOL SUCCINATE

Composition :

S AMLODIPINE-2.5MG + S METOPROLOL-25MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Metpure AM 2.5 Tablet

Metpure AM 2.5 Tablet is used to treat hypertension (high blood pressure). Also, Metpure AM 2.5 Tablet is used to treat chest pain and irregular heart rhythm. Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Metpure AM 2.5 Tablet is a combination of two drugs:  S-amlodipine (calcium channel blocker) and S-metoprolol (beta-blocker). S-amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes the muscle. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to the beta-blockers class, which works by blocking beta receptors in the heart and making the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together, they lower high blood pressure.

Take Metpure AM 2.5 Tablet as prescribed by your doctor. You are advised to take Metpure AM 2.5 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience tiredness, dizziness, slow heart rate, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), depression, stomach pain, or fluid retention. Most of these side effects of Metpure AM 2.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Metpure AM 2.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking Metpure AM 2.5 Tablet . Avoid drinking alcohol with Metpure AM 2.5 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache. Drive only if you are alert, as Metpure AM 2.5 Tablet may cause dizziness or tiredness. Avoid grapefruit or grapefruit juice with Metpure AM 2.5 Tablet as it may increase the risk of severe low blood pressure. Metpure AM 2.5 Tablet is used with caution in heart failure, during surgeries, pheochromocytoma, lung diseases, diabetes, peripheral vascular disease, hyperthyroidism, and aortic stenosis. Metpure AM 2.5 Tablet is not recommended in cardiogenic shock, hyperlipidemia, glaucoma, or liver diseases.

Uses of Metpure AM 2.5 Tablet

Metpure AM 2.5 Tablet is used to treat hypertension (high blood pressure) and manage heart conditions. The detailed uses of Metpure AM 2.5 Tablet are as follows:

  • Hypertension: Metpure AM 2.5 Tablet lowers high blood pressure and minimizes the risk of heart-related complications.
  • Angina pectoris: Metpure AM 2.5 Tablet prevents and relieves chest pain by increasing blood flow to the heart.

Have a query?

Directions for Use

  • Take Metpure AM 2.5 Tablet with or without food as advised by your doctor.
  • It is advised to take Metpure AM 2.5 Tablet once daily in the morning; however, follow your doctor's recommendation regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

Medicinal Benefits

Metpure AM 2.5 Tablet contains S-amlodipine and S-metoprolol, which are primarily used to treat high blood pressure. S-amlodipine is a calcium channel blocker that acts on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to beta-blockers that block beta receptors in the heart and make the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together, they lower high blood pressure.

How Metpure AM 2.5 Tablet Works

Metpure AM 2.5 Tablet is a combination of two drugs:  S-amlodipine (calcium channel blocker) and S-metoprolol (beta-blocker). S-amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes the muscle. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to the beta-blockers class, which works by blocking beta receptors in the heart and making the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together, they lower high blood pressure.

Storage

• Store in a cool and dry place away from sunlight.• Keep Metpure AM 2.5 Tablet out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Metpure AM 2.5 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.

What if I have taken an overdose of Metpure AM 2.5 Tablet

Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are known to be allergic to Metpure AM 2.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking Metpure AM 2.5 Tablet . Complete the full course of medication and do not stop taking Metpure AM 2.5 Tablet suddenly as it may cause recurring symptoms or worsen the condition. Avoid grapefruit or grapefruit juice with Metpure AM 2.5 Tablet as it may increase the risk of severe low blood pressure. Avoid taking Metpure AM 2.5 Tablet if you have blood circulation or heart problems, Prinzmetal’s angina (painful feeling in the chest in periods of rest), asthma, chronic obstructive pulmonary disease (COPD), breathing problems, phaeochromocytoma (tumor in the adrenal gland), low blood pressure, diabetes or metabolic acidosis (increased acidity of the blood), hyperthyroidism. Avoid drinking alcohol with Metpure AM 2.5 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache. Drive only if you are alert as Metpure AM 2.5 Tablet may cause dizziness or tiredness. If you are about to under any surgery or receive anesthetics, please inform your doctor or dentist that you are taking Metpure AM 2.5 Tablet as it may cause a very slow heartbeat.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
MetoprololAminophylline
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Metpure AM 2.5 Tablet:
Using Metpure AM 2.5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Metpure AM 2.5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
MetoprololAminophylline
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Coadministration of Aminophylline with Metpure AM 2.5 Tablet together can make Metpure AM 2.5 Tablet less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Metpure AM 2.5 Tablet may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololClonidine
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Co-administration of Clonidine and Metpure AM 2.5 Tablet may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Metpure AM 2.5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
MetoprololTizanidine
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Coadministration of Metpure AM 2.5 Tablet and Tizanidine may reduce the efficiency of Metpure AM 2.5 Tablet.

How to manage the interaction:
Taking Metpure AM 2.5 Tablet and Tizanidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. do not discontinue any medications without talking to your doctor.
MetoprololAcebutolol
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Coadministration of Acebutolol with Metpure AM 2.5 Tablet can cause abnormal heart rhythm.

How to manage the interaction:
Taking Metpure AM 2.5 Tablet and Acebutolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololArtemether
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Both Metpure AM 2.5 Tablet and Artemether may increase the blood levels and effects of Metpure AM 2.5 Tablet activity.

How to manage the interaction:
Taking Metpure AM 2.5 Tablet and Artemether together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololElvitegravir
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Taking elvitegravir may increase the metabolism of Metpure AM 2.5 Tablet.

How to manage the interaction:
Although there may be an interaction, Metpure AM 2.5 Tablet can be taken with Elvitegravir if prescribed by the doctor. Consult the doctor if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medications without talking to your doctor.
MetoprololDisopyramide
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Combine use of Metpure AM 2.5 Tablet with Disopyramide may increase the effectiveness of Disopyramide.

How to manage the interaction:
Although there may be an interaction, Metpure AM 2.5 Tablet can be taken with Disopyramide if prescribed by the doctor. Consult the doctor if you experience any symptoms such as dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medication without a doctor's advice.
MetoprololAtazanavir
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Use of Metpure AM 2.5 Tablet with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Metpure AM 2.5 Tablet and Atazanavir, it can be taken if prescribed by the doctor. Consult the doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololVerapamil
Severe
How does the drug interact with Metpure AM 2.5 Tablet:
Coadministration of Metpure AM 2.5 Tablet with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Metpure AM 2.5 Tablet can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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S AMLODIPINE-2.5MG+S METOPROLOL-25MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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S AMLODIPINE-2.5MG+S METOPROLOL-25MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine and Metoprolol. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in vegetables, fruits, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil, which may lower high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Metpure AM 2.5 Tablet Substitute

Substitutes safety advice
bannner image

Alcohol

Unsafe

Avoid alcohol consumption with Metpure AM 2.5 Tablet as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache.

bannner image

Pregnancy

Caution

Metpure AM 2.5 Tablet is a category C pregnancy drug. Metpure AM 2.5 Tablet is given to pregnant women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are pregnant.

bannner image

Breast Feeding

Caution

Metpure AM 2.5 Tablet may be excreted in human milk in small amounts. Therefore, Metpure AM 2.5 Tablet is given to breastfeeding mothers if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

bannner image

Driving

Caution

Metpure AM 2.5 Tablet may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking Metpure AM 2.5 Tablet .

bannner image

Liver

Caution

Metpure AM 2.5 Tablet should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Metpure AM 2.5 Tablet should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

It is not recommended for children as the safety and effectiveness were not established.

FAQs

Metpure AM 2.5 Tablet is used to treat hypertension (high blood pressure). It is also used to treat chest pain and irregular heart rhythm.

Metpure AM 2.5 Tablet is a combination of two drugs, namely: S-amlodipine (calcium channel blocker) and S-metoprolol (beta-blocker). S-amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. S-metoprolol belongs to the beta-blockers class that works by blocking beta receptors in the heart and makes the heartbeat slow and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Thus, together they lower high blood pressure.

Metpure AM 2.5 Tablet cause common side effects like tiredness, dizziness, slow heart rate, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), depression, stomach pain, or fluid retention.

Metpure AM 2.5 Tablet should be used with caution in diabetic patients as it may increase the risk of severe low blood sugar levels. Therefore, if you have diabetes, inform your doctor before taking Metpure AM 2.5 Tablet . Also, regular monitoring of blood sugar levels is recommended while taking Metpure AM 2.5 Tablet .

Metpure AM 2.5 Tablet may cause dizziness when standing up from sitting or lying position suddenly. Therefore, to avoid such effects, it is advised to stand up slowly from sitting or lying position.

Metpure AM 2.5 Tablet may cause high potassium levels in the blood and cause adverse effects on overdose. Therefore, take Metpure AM 2.5 Tablet only in doses as prescribed by your doctor.

Metpure AM 2.5 Tablet is may be safe to use in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

Do not stop taking Metpure AM 2.5 Tablet suddenly as it may cause recurring symptoms or worsen the condition.

Eating well, exercising regularly, maintaining a healthy weight, quitting smoking, getting enough sleep, and managing stress are all lifestyle changes that can help lower blood pressure.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - MET0126

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 10, 2025 | 3:13 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.5344.pdf
  2. https://www.medicines.org.uk/emc/files/pil.6068.pdf
  3. https://www.drugs.com/metoprolol.html
  4. https://www.drugs.com/amlodipine.html

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