Mignar 25-MF Tablet 10's

Mignar 25-MF Tablet 10's belongs to the class of medications called ‘antidiabetic drugs’ used to treat type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than normal. It occurs when the body does not produce enough insulin (utilizes glucose to produce energy) or if produced, it cannot function properly in the body.

Mignar 25-MF Tablet 10's contains Miglitol and Metformin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Miglitol works by inhibiting intestinal enzymes that break complex sugars into simple sugars like glucose. Together, Mignar 25-MF Tablet 10's can effectively prevent the rise in glucose levels in the body.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Mignar 25-MF Tablet 10's are flatulence (gas), diarrhoea, abdominal pain, feeling sick (nausea), being sick (vomiting) and loss of appetite. These side effects can be reduced if this medicine is taken with food or after a meal. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Mignar 25-MF Tablet 10's if you are allergic to any contents of it. Mignar 25-MF Tablet 10's is not recommended if you are having any intestinal problems such as inflammation, ulcers, blockage, hernia, liver problems, severe kidney impairment, uncontrolled diabetes, severe dehydration, severe infections, and a recent history of heart attack or heart failure. Mignar 25-MF Tablet 10's is not recommended for children and adolescents below 18 years, pregnant women, and breastfeeding mothers. It should be used with caution in elderly people as they may require dose adjustments. Mignar 25-MF Tablet 10's may interact with alcohol and worsen the condition. Mignar 25-MF Tablet 10's may cause hypoglycemia (low glucose levels), so avoid driving if you develop weakness, dizziness, fast heartbeat, or decrease in alertness.

Mignar 25-MF Tablet 10's is a combination of two drugs: Miglitol and Metformin. This combination therapy is preferred in patients with poorly controlled diabetes. It reduces blood glucose levels, especially post-prandial glucose levels (glucose levels after meals) in type 2 diabetes mellitus patients. An increase in post-prandial glucose levels can be a risk factor for diabetes complications such as tissue and organ damage. So, a decrease in glucose levels helps control diabetes, reduce this risk and improve healthy life.

• Flatulence (gas)
• Diarrhoea
• Abdominal pain
• Feeling sick (nausea)
• Being sick (vomiting)
• Loss of appetite

Mignar 25-MF Tablet 10's may cause a rare and serious side effect ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing. It is a life-threatening condition that requires immediate medical attention. Inform your doctor if you have any severe liver or kidney problems as their normal functioning is required to eliminate excess lactic acid from the body.  Consumption of alcohol, prolonged fasting, dehydration, uncontrolled diabetes, serious infections, and liver problems increases the risk of lactic acidosis. If you have dehydration (severe loss of body fluids) due to severe vomiting, diarrhoea, exposure to heat, or fever, stop taking Mignar 25-MF Tablet 10's and immediately seek medical attention. Mignar 25-MF Tablet 10's may cause hypoglycemia (low blood sugar) and its symptoms include sweating, dizziness, palpitations (pounding heartbeat), and shivering, etc. Whenever you experience any of these symptoms, immediately consume candies or glucose biscuits rather than ordinary sugar. If your condition doesn’t improve, consult your doctor immediately.

Drug-Drug Interactions: Mignar 25-MF Tablet 10's may interact with other antidiabetic drugs, diuretics or water pills, nonsteroidal anti-inflammatory drugs (ibuprofen and celecoxib), antacids (cimetidine and omeprazole), antiasthma drugs (salbutamol and terbutaline), corticosteroids, anti-HIV drug (dolutegravir), iodinated X-ray contrast agents, medications used to treat high blood pressure (verapamil, ramipril, losartan, and telmisartan, etc.), antibacterial (rifampicin and trimethoprim), a medication to treat chest pain (ranolazine), anticancer drugs (vandetanib and olaparib), an antifungal drug (isavuconazole), medicines that help in digestion (pancreatin and amylase), and medicines used to treat constipation (bisacodyl, senna, and sodium picosulfate, etc.). Mignar 25-MF Tablet 10's may also modify the effect of long-acting medicines such as slow-release, extended-release, modified-release, or sustained-release.

Drug-Food Interactions: Avoid intake of alcoholic beverages with Mignar 25-MF Tablet 10's as it increases the risk of lactic acidosis.

Drug-Disease Interactions: Mignar 25-MF Tablet 10's should be avoided in patients with liver or severe kidney diseases, heart diseases (like congestive heart failure and myocardial infarction), severe dehydration, uncontrolled diabetes, and gastrointestinal disorders (inflammation, ulcers, blockage, or hernia).

• IBUPROFEN
• CELECOXIB
• CIMETIDINE
• OMEPRAZOLE
• SALBUTAMOL
• TERBUTALINE
• DOLUTEGRAVIR
• VERAPAMIL
• RAMIPRIL
• LOSARTAN
• TELMISARTAN
• RIFAMPICIN
• TRIMETHOPRIM
• RANOLAZINE
• VANDETANIB
• OLAPARIB
• ISAVUCONAZOLE
• PANCREATIN
• AMYLASE
• BISACODYL
• SENNA GLYCOSIDES
• SODIUM PICOSULFATE

• Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grains.
• Eat at regular intervals. Do not take the long gap between a meal or snack.
• Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
• Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
• Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
• Replace refined carbohydrates containing whole-grain foods and increase intake of fruits and veggies and other fiber-enriched foods.
• Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. You may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil for frying.
• Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress-related blood sugar changes.
• Opt for low-fat dairy products (low-fat yogurt, fat-free milk, cheese, etc.).
• Keep your blood pressure as normal (120/80) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.

• Beware of hypoglycemia (low blood sugar level) symptoms include sweating, dizziness, palpitations, shivering, confusion, irritability, etc. Whenever you experience these symptoms, try to eat candies or glucose biscuits and get in touch with your doctor. Make sure you carry these with you at all times, especially for long travels.
• Before undergoing examinations such as an X-ray or CT scan or undergoing surgery, inform your doctor that you are taking Mignar 25-MF Tablet 10's. This medicine needs to be stopped before undergoing surgery or examination. 

Type 2 Diabetes Mellitus: It is a chronic or lifelong disease that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin or are resistant to insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, which is also known as adult-onset diabetes. Type 2 diabetes symptoms include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also include neuropathy (nerve problems), nephropathy (kidney problems) and retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction and increase chance of heart attack or stroke.