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Mignar 25-MF Tablet belongs to the class of medications called ‘antidiabetic drugs’ used to treat type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than normal. It occurs when the body does not produce enough insulin (utilizes glucose to produce energy) or if produced, it cannot function properly in the body.
Mignar 25-MF Tablet contains Miglitol and Metformin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Miglitol works by inhibiting intestinal enzymes that break complex sugars into simple sugars like glucose. Together, Mignar 25-MF Tablet can effectively prevent the rise in glucose levels in the body.
You should take this medicine exactly as prescribed by the doctor. The common side-effects of Mignar 25-MF Tablet are flatulence (gas), diarrhoea, abdominal pain, feeling sick (nausea), being sick (vomiting) and loss of appetite. These side effects can be reduced if this medicine is taken with food or after a meal. However, if any of these side effects persist or get worse, inform your doctor immediately.
It is not recommended to take Mignar 25-MF Tablet if you are allergic to any contents of it. Mignar 25-MF Tablet is not recommended if you are having any intestinal problems such as inflammation, ulcers, blockage, hernia, liver problems, severe kidney impairment, uncontrolled diabetes, severe dehydration, severe infections, and a recent history of heart attack or heart failure. Mignar 25-MF Tablet is not recommended for children and adolescents below 18 years, pregnant women, and breastfeeding mothers. It should be used with caution in elderly people as they may require dose adjustments. Mignar 25-MF Tablet may interact with alcohol and worsen the condition. Mignar 25-MF Tablet may cause hypoglycemia (low glucose levels), so avoid driving if you develop weakness, dizziness, fast heartbeat, or decrease in alertness.
Mignar 25-MF Tablet used in the treatment of type 2 diabetes mellitus. The detailed uses of Mignar 25-MF Tablet are as follows:
Mignar 25-MF Tablet is a combination of two drugs: Miglitol and Metformin. This combination therapy is preferred in patients with poorly controlled diabetes. It reduces blood glucose levels, especially post-prandial glucose levels (glucose levels after meals) in type 2 diabetes mellitus patients. An increase in post-prandial glucose levels can be a risk factor for diabetes complications such as tissue and organ damage. So, a decrease in glucose levels helps control diabetes, reduce this risk and improve healthy life.
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Consumption of alcohol may increase the risk of side effects and worsen the condition.
Caution
Mignar 25-MF Tablet is a category B medicine and may not cause harmful effects to the unborn baby. However, it should be used in pregnant women only if clinically needed.
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Mignar 25-MF Tablet should not be given to breastfeeding mothers as it may pass in breast milk and cause adverse effects in the nursing baby.
Caution
Mignar 25-MF Tablet may impair alertness or decrease concentration, so avoid driving or operating heavy machinery in such cases.
Caution
Mignar 25-MF Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.
Caution
Mignar 25-MF Tablet is not recommended for use in patients with severe kidney impairment. In patients with mild to moderate kidney diseases, your doctor may have to adjust the dose.
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Mignar 25-MF Tablet is not recommended for children and adolescents below 18 years of age.
Consult your doctor
Please inform your doctor if you have a history of heart disease before using Mignar 25-MF Tablet . Your doctor will prescribe it only if the benefits outweigh the risks.
Consult your doctor
Limited information available for use of Mignar 25-MF Tablet in elderly patients. Please consult your doctor.

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Mignar 25-MF Tablet may cause a rare and serious side effect ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing. It is a life-threatening condition that requires immediate medical attention. Inform your doctor if you have any severe liver or kidney problems as their normal functioning is required to eliminate excess lactic acid from the body. Consumption of alcohol, prolonged fasting, dehydration, uncontrolled diabetes, serious infections, and liver problems increases the risk of lactic acidosis. If you have dehydration (severe loss of body fluids) due to severe vomiting, diarrhoea, exposure to heat, or fever, stop taking Mignar 25-MF Tablet and immediately seek medical attention. Mignar 25-MF Tablet may cause hypoglycemia (low blood sugar) and its symptoms include sweating, dizziness, palpitations (pounding heartbeat), and shivering, etc. Whenever you experience any of these symptoms, immediately consume candies or glucose biscuits rather than ordinary sugar. If your condition doesn’t improve, consult your doctor immediately.
Drug-Drug Interactions: Mignar 25-MF Tablet may interact with other antidiabetic drugs, diuretics or water pills, nonsteroidal anti-inflammatory drugs (ibuprofen and celecoxib), antacids (cimetidine and omeprazole), antiasthma drugs (salbutamol and terbutaline), corticosteroids, anti-HIV drug (dolutegravir), iodinated X-ray contrast agents, medications used to treat high blood pressure (verapamil, ramipril, losartan, and telmisartan, etc.), antibacterial (rifampicin and trimethoprim), a medication to treat chest pain (ranolazine), anticancer drugs (vandetanib and olaparib), an antifungal drug (isavuconazole), medicines that help in digestion (pancreatin and amylase), and medicines used to treat constipation (bisacodyl, senna, and sodium picosulfate, etc.). Mignar 25-MF Tablet may also modify the effect of long-acting medicines such as slow-release, extended-release, modified-release, or sustained-release.
Drug-Food Interactions: Avoid intake of alcoholic beverages with Mignar 25-MF Tablet as it increases the risk of lactic acidosis.
Drug-Disease Interactions: Mignar 25-MF Tablet should be avoided in patients with liver or severe kidney diseases, heart diseases (like congestive heart failure and myocardial infarction), severe dehydration, uncontrolled diabetes, and gastrointestinal disorders (inflammation, ulcers, blockage, or hernia).
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RXGlenmark Pharmaceuticals Ltd
₹181
(₹18.1 per unit)
Mignar 25-MF Tablet is used to treat type 2 diabetes mellitus.
Mignar 25-MF Tablet contains Miglitol and Metformin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Miglitol works by inhibiting intestinal enzymes that break complex sugars into simple sugars like glucose. Together, Mignar 25-MF Tablet can effectively prevent the rise in glucose levels in the body.
Mignar 25-MF Tablet can be taken on an empty stomach. However, it is advised to take with food or after meals to reduce the bowel side-effects and increase its efficiency.
Inform your doctor before having an X-ray or CT scan that you are taking Mignar 25-MF Tablet . Some imaging scans may involve the use of the injection of contrast materials that contain iodine. Concomitant use of this injection with Mignar 25-MF Tablet may affect your kidney function. So, the doctor may advise you to stop Mignar 25-MF Tablet before the examination and will decide when to restart it.
Mignar 25-MF Tablet may cause hypoglycemia (low blood sugar level) characterized by sweating, dizziness, palpitations, shivering, confusion, irritability, etc. If you experience these symptoms, try to eat candies or glucose biscuits. If your condition doesn't improve, consult your doctor immediately.
Mignar 25-MF Tablet is recommended for the treatment of type 2 diabetes and not used for treating type 1 diabetes, a condition which occurs mainly due to deficiency of insulin.
Mignar 25-MF Tablet is safe when used as per the dose and duration advised by a doctor.
Mignar 25-MF Tablet causes side effects such as diarrhoea, abdominal pain, feeling sick (nausea), vomiting, and loss of appetite. However, these side effects are temporary and do not require any medical attention, as they will gradually reduce over time. Please, contact a doctor if these persist for longer durations.
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