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Mignar25-MF Tablet SR is used to treat type 2 diabetes mellitus. It contains Miglitol and Metformin which work by decreasing glucose production in liver and intestinal glucose uptake and inhibiting intestinal enzymes that break complex sugars into simple sugars like glucose. In some cases, this medicine may cause side effects such as stomach pain, heartburn, diarrhoea, nausea, and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Mignar25-MF Tablet SR

Mignar25-MF Tablet SR is prescribed to help manage blood sugar levels in adults with type 2 diabetes mellitus. It combines two active therapies that work in different ways to keep your blood glucose within a target range. This medicine is typically prescribed when diet and exercise alone are not enough to control blood sugar.

To get the best results, you must take Mignar25-MF Tablet SR consistently every day exactly as directed by your doctor. It is usually taken with the first bite of your main meals to help manage the rise in blood sugar that happens after eating. Combining this medicine with a balanced, low-sugar diet and regular physical activity will significantly improve how well it works.

Some people may experience mild side effects when starting this medication, such as gas, stomach pain, or diarrhoea. While these issues often improve as your body adjusts, you should contact your doctor immediately if you experience severe abdominal pain, persistent vomiting, or signs of low blood sugar.

Before taking Mignar25-MF Tablet SR, tell your doctor if you have a history of kidney disease, liver damage, or severe stomach and bowel disorders. Do not take this if you have severe kidney impairment, diabetic ketoacidosis, or inflammatory bowel disease. Talk to your doctor or pharmacist to ensure this medicine is safe for your specific health profile.

Drinking alcohol while taking Mignar25-MF Tablet SR can increase the risk of a rare but serious condition called lactic acidosis because of metformin, so it is best to limit or avoid alcohol completely. Certain medications like water pills or steroids can affect how your blood sugar is controlled, so share a full list of your current medicines with your pharmacist. If you are pregnant, breastfeeding, or over the age of 65, talk to your doctor before starting this medication.

Uses of Mignar25-MF Tablet SR

Mignar25-MF Tablet SR is used to treat Type 2 diabetes mellitus. The detailed uses of Mignar25-MF Tablet SR are as follows:

  • Type 2 diabetes mellitus: Mignar25-MF Tablet SR helps lower high blood sugar levels in adults when diet, exercise, and other single-ingredient medicines are not sufficient.
  • Post-meal blood sugar spikes: Mignar25-MF Tablet SR specifically targets and reduces the sharp rise in blood glucose that occurs immediately after eating meals.
     

Key Benefits

By keeping your blood sugar in a stable, healthy range, Mignar25-MF Tablet SR brings several key health benefits:

  • Prevents sugar spikes: It helps prevent the sudden spikes and crashes that can leave you feeling tired or sluggish throughout the day.
  • Reduces complications: This medicine lowers your long-term risk of serious diabetes-related complications, such as nerve damage, kidney issues, and vision loss.
  • Make treatment easier: The combination of two working ingredients in one tablet simplifies your daily treatment plan, making it easier to stay on track with your blood sugar management.

Directions for Use

  • Mignar25-MF Tablet SR can be taken with food or as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Mignar25-MF Tablet SR as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Mignar25-MF Tablet SR Works

Mignar25-MF Tablet SR contains two active medicines that work together to lower your blood sugar through different pathways in the body. The first active ingredient, miglitol, works in your intestines. It slows down the breakdown of complex carbohydrates (like starches and sugars) into simple sugars. This delays sugar absorption into your blood, which prevents your blood glucose from spiking rapidly after you eat. The second active ingredient, metformin, works primarily in your liver and muscles. It reduces the amount of sugar your liver produces and releases into your bloodstream. At the same time, it helps your body's cells become more sensitive to insulin, allowing them to absorb and use sugar from your blood more effectively.
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Alcohol

Unsafe

Consumption of alcohol may increase the risk of side effects and worsen the condition.

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Pregnancy

Caution

Mignar25-MF Tablet SR is a category B medicine and may not cause harmful effects to the unborn baby. However, it should be used in pregnant women only if clinically needed.

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Breast Feeding

Unsafe

Mignar25-MF Tablet SR should not be given to breastfeeding mothers as it may pass in breast milk and cause adverse effects in the nursing baby.

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Driving

Caution

Mignar25-MF Tablet SR may impair alertness or decrease concentration, so avoid driving or operating heavy machinery in such cases.

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Liver

Caution

Mignar25-MF Tablet SR should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Mignar25-MF Tablet SR is not recommended for use in patients with severe kidney impairment. In patients with mild to moderate kidney diseases, your doctor may have to adjust the dose.

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Children

Unsafe

Mignar25-MF Tablet SR is not recommended for children and adolescents below 18 years of age.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Mignar25-MF Tablet SR. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Mignar25-MF Tablet SR in elderly patients. Please consult your doctor.

What if I have taken an overdose of Mignar25-MF Tablet SR

If you take too much of this medicine, seek immediate medical attention or contact a poison control centre right away. An overdose can lead to severe low blood sugar or a dangerous buildup of acid in your blood.

Diet & Lifestyle Advise

  • Monitor your carbohydrate intake: Since this medicine helps control post-meal sugar spikes, eating consistent amounts of complex carbohydrates (like whole grains and vegetables) rather than simple sugars will help the medicine work more effectively.
  • Treat low blood sugar with pure glucose: If you experience low blood sugar while taking Mignar25-MF Tablet SR, use pure glucose tablets or gel rather than regular sugar or soda. This medicine delays the digestion of common table sugars, meaning normal sweets will not raise your blood sugar quickly enough in an emergency.
  • Stay active: Aim for at least 150 minutes of moderate exercise, such as brisk walking, per week to help your muscles use sugar more efficiently and improve your overall insulin sensitivity.
  • Keep a regular meal schedule: Skipping meals while taking blood sugar-lowering medications can increase your risk of low blood sugar. Try to eat your meals at the same times each day.
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How Soon It Starts Working

The time required for Mignar25-MF Tablet SR to start to work: Mignar25-MF Tablet SR shows its action within 1 to 2 hours of administration. The time for which the effects of Mignar25-MF Tablet SR last: Mignar25-MF Tablet SR effect lasts for 8 to 12 hours.

What if you forget to take Mignar25-MF Tablet SR

If you miss a dose of Mignar25-MF Tablet SR, take it with your next main meal if you are about to eat. If you remember between meals, skip the missed dose and take your next regular dose with your next scheduled meal. Do not take a double dose to make up for a missed one.

Storage

• Store Mignar25-MF Tablet SR at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the tablets in their original blister pack or container to protect them from moisture and direct light.

Drug Warnings

  • Check the packaging: Always check the tablet packaging before use; do not take the medicine if the foil is broken, torn, or shows signs of tampering.
  • Inform your healthcare provider: Inform any healthcare provider, including your dentist, that you are taking Mignar25-MF Tablet SR before undergoing any medical procedures or contrast-dye imaging scans.
  • Monitor kidney function: Monitor your kidney function regularly; your doctor will likely order blood tests to check your kidneys before and during your treatment.
  • Keep glucose with you: Keep a source of fast-acting glucose (such as glucose tablets) with you at all times in case you experience symptoms of low blood sugar.
  • Be cautious while driving: Be cautious when driving or operating machinery if you feel dizzy or weak, as these can be signs of fluctuating blood sugar levels.

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Other diabetes medicines: Insulin or sulfonylureas may increase the risk of low blood sugar when combined.
  • Digestive enzymes or charcoal preparations: they may reduce the effectiveness of this medicine by decreasing its absorption.
  • Certain blood pressure medicines, like beta-blockers: it can mask the warning signs of low blood sugar, such as a rapid heart rate.

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verifiedApollotooltip
  • High-fibre foods: Taking this medicine with high-fibre foods may occasionally increase stomach side effects like gas and bloating.
  • Alcohol: it can significantly increase the risk of a dangerous condition called lactic acidosis and should be avoided.
     

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Mignar25-MF Tablet SR is used to treat type 2 diabetes mellitus.
Mignar25-MF Tablet SR contains Miglitol and Metformin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Miglitol works by inhibiting intestinal enzymes that break complex sugars into simple sugars like glucose. Together, Mignar25-MF Tablet SR can effectively prevent the rise in glucose levels in the body.
Mignar25-MF Tablet SR can be taken on an empty stomach. However, it is advised to take with food or after meals to reduce the bowel side-effects and increase its efficiency.
Inform your doctor before having an X-ray or CT scan that you are taking Mignar25-MF Tablet SR. Some imaging scans may involve the use of the injection of contrast materials that contain iodine. Concomitant use of this injection with Mignar25-MF Tablet SR may affect your kidney function. So, the doctor may advise you to stop Mignar25-MF Tablet SR before the examination and will decide when to restart it.
Mignar25-MF Tablet SR may cause hypoglycemia (low blood sugar level) characterized by sweating, dizziness, palpitations, shivering, confusion, irritability, etc. If you experience these symptoms, try to eat candies or glucose biscuits. If your condition doesn't improve, consult your doctor immediately.
Mignar25-MF Tablet SR is recommended for the treatment of type 2 diabetes and not used for treating type 1 diabetes, a condition which occurs mainly due to deficiency of insulin.
Mignar25-MF Tablet SR is safe when used as per the dose and duration advised by a doctor.
Mignar25-MF Tablet SR causes side effects such as diarrhoea, abdominal pain, feeling sick (nausea), vomiting, and loss of appetite. However, these side effects are temporary and do not require any medical attention, as they will gradually reduce over time. Please, contact a doctor if these persist for longer durations.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol increases your risk of developing lactic acidosis, a rare but life-threatening side effect, and can also cause unpredictable changes in your blood sugar. Talk to your doctor for personalised advice.
While Mignar25-MF Tablet SR is not a weight-loss drug, some people may lose a small amount of weight or maintain their weight while taking it. This is because one of its active ingredients can help modestly reduce caloric intake for better glucose control, which can contribute to weight stability. Talk to your doctor if you have concerns about your weight.
Mild gas and bloating are common when starting Mignar25-MF Tablet SR as your digestive system adjusts to the medicine. These symptoms usually improve over a few weeks, but if they are severe, painful, or do not go away, talk to your doctor.
This medicine slows down the digestion of table sugar (sucrose) and complex carbs. If your blood sugar drops, ordinary sweets or sodas will take too long to work, so you must use pure glucose tablets or gel, which are absorbed immediately. Talk to your doctor for more details on managing low blood sugar.
This medicine is generally not recommended during pregnancy or breastfeeding. Your doctor will likely suggest alternative treatments, such as insulin, to manage your blood sugar safely during this time. Talk to your doctor about your options.
Yes, this medicine works best when combined with a healthy diet and regular physical activity. Relying on the medication alone without dietary control will not produce the best results for your blood sugar levels. Talk to your doctor or a dietitian for a structured meal plan.
When taken alone, Mignar25-MF Tablet SR rarely causes low blood sugar. However, the risk increases if you take it alongside other diabetes medications like insulin or sulfonylureas, skip meals, or exercise excessively. Talk to your doctor about how to recognise and manage low blood sugar.
Lactic acidosis is a rare but very serious medical emergency caused by a buildup of lactic acid in the blood. The risk is extremely low if your kidneys and liver are healthy and you avoid heavy alcohol use. Talk to your doctor immediately if you experience unusual muscle pain, deep breathing, or extreme tiredness.

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Country of origin

India
Other Info - MI42683
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