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compositionComposition:CAFFEINE-100MG+ERGOTAMINE-1MG
prescription
Prescription Medicine
info
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Migranil Tablet is used to prevent or treat migraine. It contains Ergotamine (ergot alkaloid) and caffeine (methylxanthine). Ergotamine works by narrowing the blood vessels in the brain. Caffeine increases the absorption of Ergotamine and narrows widened blood vessels. In some cases, this medication may cause nausea, vomiting, stomach upset, and restlessness. It is recommended not to take this medication if you are pregnant, think you may be pregnant or if you are breastfeeding.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CAFFEINE-100MG+ERGOTAMINE-1MG

Manufacturer/Marketer :

Inga Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Migranil Tablet

Migranil Tablet is a combination medicine indicated to prevent and treat migraine. Migraine is a neurological condition which is characterised by an intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift.

Migranil Tablet contains Ergotamine (ergot alkaloid) and caffeine (methylxanthine). Ergotamine works by narrowing the blood vessels in the brain. Caffeine increases the absorption of ergotamine and narrows widened blood vessels.

In some cases, Migranil Tablet may cause side effects such as nausea, vomiting, stomach upset, and restlessness. These side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Do not take Migranil Tablet if you are pregnant, think you may be pregnant or if you are breastfeeding. Migranil Tablet may cause dizziness, so drive only if you are alert. Migranil Tablet is not recommended for children below 18 years. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Migranil Tablet

Migranil Tablet used in the treatment of Migraine. The detailed use of Migranil Tablet is as follows:

  • Treatment of Migraine headaches: Migranil Tablet is used to prevent vascular headaches, such as e.g., migraine, migraine variant, by preventing blood vessels in the head from expanding and causing headaches.

Key Benefits

Migranil Tablet is a combination medicine indicated to prevent and treat migraine. Migranil Tablet contains Ergotamine (ergot alkaloid) and caffeine (methylxanthine). Ergotamine works by narrowing the blood vessels in the brain. Caffeine increases the absorption of ergotamine and narrows widened blood vessels. Together, it help treat migraine.

Directions for Use

  • Take Migranil Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Migranil Tablet Works

Migranil Tablet contains Ergotamine (ergot alkaloid) and caffeine (methylxanthine). Ergotamine works by narrowing the blood vessels in the brain. Caffeine increases the absorption of ergotamine and narrows widened blood vessels.
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Alcohol

Caution

Avoid or limit the consumption of alcohol.

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Pregnancy

Unsafe

Avoid taking Migranil Tablet if you are pregnant. Please consult the doctor if you are pregnant or if you have any concerns regarding this.

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Breast Feeding

Unsafe

Migranil Tablet is not recommended during lactation. Please consult the doctor if you are breastfeeding.

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Driving

Caution

Migranil Tablet may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Migranil Tablet is not recommended for people with severe liver impairment. Please consult the doctor if you have liver problems or any concerns.

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Kidney

Consult your doctor

Migranil Tablet is not recommended for people with severe kidney impairment. Please consult the doctor if you have kidney problems or any concerns.

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Children

Unsafe

Migranil Tablet is not recommended for children below 18 years.

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Heart

Caution

Migranil Tablet should be used with caution in heart patients, as it can cause an increase in the risk of side effects.

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Geriatrics

Consult your doctor

Limited information available about the use of Migranil Tablet in geriatric patients. Please consult your physician.

What if I have taken an overdose of Migranil Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Migranil Tablet may include vomiting, numbness, tingling sensation, pain, blue hands and feet, lack of pulse, dizziness or lightheadedness, fainting, drowsiness, unconsciousness, coma, and seizures. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Diet & Lifestyle Advise

  • Maintaining a healthy diet and exercising regularly helps in improving overall health and boosts self-esteem.
  • Avoid bright lights, loud noise, and extreme temperatures.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Massage your scalp to ease the pain.
  • Lie down in a quiet, dark room.
  • Place a cold cloth over your forehead or neck.
  • Avoid smoking, alcohol, and caffeinated drinks. 
  • Learn what triggers your migraine and try avoiding them.
  • Stay hydrated. Drink plenty of fluids.
  • Learn relaxation skills as they help in reducing stress.

Health Queries

What are the recommended medical next steps for a persistent, five-day headache that is unresponsive to prescribed migraine medication (such as Migranil), especially when preceded by eye pain and excessive tearing?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Since your prescribed Migranil hasn't provided relief, and you are experiencing eye pain and tearing, it is very important to seek a professional medical evaluation promptly. These symptoms can sometimes point to specific types of headaches, like cluster headaches, or other conditions that need targeted treatment. Please visit your doctor, a neurologist, or an urgent care clinic as soon as possible. They can safely evaluate your symptoms, ensure your eyes are healthy, and find a more effective treatment plan to help you feel better.

What are the clinical recommendations for managing chronic, refractory headaches of ten years' duration that have not responded to daily Migranil use or various previous medical treatments?

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Daily use of Migranil can sometimes lead to a cycle called medication overuse headaches, which actually keeps the pain going. A vital next step is working closely with a headache specialist. They can help you safely taper off daily Migranil and discuss tailored preventive options?such as specific nerve blocks, daily preventive generic medications, or newer targeted therapies. Keeping a detailed headache diary can also help guide your specialist to the right solution.

Why do my headache medicines, Migranil and Topaz, take so long to provide relief?

Vikas Singh

Vikas Singh

M Pharmacy

Topaz (topiramate) is a daily preventive medication; it does not stop an active headache but builds up in your system over several weeks to reduce how often migraines occur. On the other hand, Migranil (ergotamine) is meant for active relief, but during a migraine, your digestive system naturally slows down, which can delay how quickly your body absorbs the tablet. Please hang in there, and consider discussing these timings with your doctor to help optimize your relief plan.

I have a headache on one side of my head and I am vomiting. What medicine should I take for relief?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

It sounds like you might be experiencing a migraine. For temporary relief from the headache, over-the-counter pain relievers like ibuprofen or acetaminophen can help. To address the vomiting, an anti-nausea medication like metoclopramide can be effective. I highly recommend resting in a dark, quiet room and sipping water slowly to stay hydrated. Since these symptoms can be distressing, please consult a doctor for a proper diagnosis and to discuss prescription options like triptans if needed. Seek immediate emergency care if you experience a sudden, extremely severe headache, confusion, or difficulty speaking.

She has been suffering from severe sinusitis for the past 7 years and has been taking 3 Migranil tablets daily for the last 4 years. What alternative medicines can you suggest for her severe headaches?

Veda Maddala

Veda Maddala

M Pharmacy

Taking three Migranil tablets daily for four years is highly dangerous and is likely causing "medication overuse headaches." Migranil contains ergotamine, which can cause severe vascular complications if overused. She must consult a doctor or neurologist immediately to safely taper off this medication. For alternative management: 1. Treat the Sinusitis: Consult an ENT specialist. Nasal steroid sprays and saline rinses can reduce sinus pressure. 2. Preventative Therapy: A doctor can prescribe safe daily preventatives like Amitriptyline, Propranolol, or Flunarizine to reduce headache frequency. 3. Acute Relief: Switch to safer rescue medications (like triptans or paracetamol) used strictly under medical supervision to avoid rebound headaches.
health query

Have a query?

How Soon It Starts Working

The time required for Migranil Tablet to start to work: Migranil Tablet ideally shows its action within an hour after administration. The time for which the effects of Migranil Tablet last: The duration of action for Migranil Tablet is clinically unknown.

What if you forget to take Migranil Tablet

If you miss a dose of Migranil Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep Migranil Tablet out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not take Migranil Tablet if you are allergic to any of its components. Inform the doctor if you have high blood pressure, coronary artery disease, problems with circulation, severe blood infection, liver or kidney problems. Do not take Migranil Tablet if you are pregnant or breastfeeding. Migranil Tablet may cause dizziness, so drive only if you are alert. Migranil Tablet is not recommended for children below 18 years. Let the doctor know if you take other medicines, including supplements and herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions: Inform the doctor if you are taking antifungals (itraconazole, ketoconazole), antibiotics (clarithromycin, erythromycin), HIV medicines (indinavir, nelfinavir, ritonavir, troleandomycin)

Drug-Food Interactions: Avoid consuming grapefruit juice while taking this medicine.

Drug-Disease Interactions: Inform the doctor if you have high blood pressure, severe liver or kidney problems or circulation problems.

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIMIGRAINE AGENTS]

FAQs

Migranil Tablet is used to treat Migraine.
Migranil Tablet works by preventing blood vessels in the head from expanding and causing headaches.
Do not discontinue Migranil Tablet without consulting your doctor. To treat your condition effectually, continue taking Migranil Tablet for as long as prescribed. Do not hesitate to speak with your doctor if you experience difficulty taking Migranil Tablet .
Migranil Tablet is not indicated for treating other types of headaches as it lacks analgesic properties. It is used to prevent and treat migraine headaches only.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MedlinePlus. A601048 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  2. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Ergotamine And Caffeine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Michelle Ngo, Prasanna Tadi Ergotamine/Caffeine. NIH. National Library of Medicine. National Center for biotechnology Information. PMC. PubMed Central. July 2022. [Accessed on 16th January 2023]Check here
  5. Cintex Services, LLC. ERGOTAMINE TARTRATE AND CAFFEINE- ergotamine tartrate and caffeine tablet, film coated. Dailymed.com. [Revised in December 2021]. [Accessed on 16th January 2023]Check here
  6. MIMS.com. Ergotamine + Caffeine. [Accessed on 16th January 2023] + caffeine?mtype=genericCheck here
  7. New Zealand Medicines and Medical Devices Safety Authority (Medsafe). Cafergottab Consumer Medicine Information (CMI). Wellington, NZ: Medsafe; 2024. [Accessed on 02 Jun. 2026]Check here

Country of origin

INDIA

Manufacturer/Marketer address

Inga House, Mahakali Road, Andheri East, Mumbai 400 093, India.
Other Info - MIG0007

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