Migrest Total Kit Tablet 1's
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About Migrest Total Kit Tablet 1's
Migrest Total Kit Tablet 1's is a combination medicine used for the symptomatic treatment of migraine, and any medical condition with concomitant nausea/vomiting and fever/pain. Migraine is a neurological condition that can cause severe throbbing pain or a pulsing sensation, usually on one side of the head, eyes, face, and neck. Symptoms may include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.
Migrest Total Kit Tablet 1's is a combination of three drugs, namely: Domperidone, flunarizine, and Paracetamol. Domperidone prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone –CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Flunarizine is a calcium channel blocker that works by preventing the narrowing of blood vessels in the head thereby preventing migraine headache. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain.
Your doctor will recommend how often you take Migrest Total Kit Tablet 1's based on your medical condition. Some people may experience some side effects like weight gain, drowsiness, dryness in the mouth. Most of these side effects of Migrest Total Kit Tablet 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
You can increase the efficacy of Migrest Total Kit Tablet 1's by taking a small meal or snacks frequently. Do not take Migrest Total Kit Tablet 1's if you are allergic to Migrest Total Kit Tablet 1's and other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Migrest Total Kit Tablet 1's. Inform your doctor if you have heart, kidney, and liver disease. Prolonged intake of Migrest Total Kit Tablet 1's may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking a higher dose. If you experience heart rhythm disorders like palpitations, trouble in breathing, or loss of consciousness after taking Migrest Total Kit Tablet 1's, immediately contact your doctor. Migrest Total Kit Tablet 1's is not recommended n depression, Parkinson's disease, or breast cancer.
Uses of Migrest Total Kit Tablet 1's
Migrest Total Kit Tablet 1's is used for the treatment of migraine. The detailed uses of Migrest Total Kit Tablet 1's include:
- Migraine relief: Migrest Total Kit Tablet 1's helps in relieving acute migraine attacks by reducing headache, nausea, and sensitivity to light or sound.
- Pain management: It contains paracetamol, which acts as an analgesic and antipyretic, reducing headache and fever associated with migraine.
- Prevention of nausea and vomiting: Migrest Total Kit Tablet 1's helps control nausea and vomiting that often accompany migraine episodes.
- Improved blood flow: Migrest Total Kit Tablet 1's works by improving blood flow to the brain and preventing constriction of blood vessels, thus reducing the frequency and intensity of migraine attacks.
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Directions for Use
- Migrest Total Kit Tablet 1's can be taken with or without food as prescribed by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow it as a whole with a glass of water.
- Do not chew, crush or break it.
Medicinal Benefits
Migrest Total Kit Tablet 1's is a combination of three drugs, namely: Domperidone, flunarizine, and Paracetamol belong to the class anti-migraine agents used for the treatment of migraine. Domperidone prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone –CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Flunarizine is a calcium channel blocker that works by preventing the narrowing of blood vessels in the head thereby preventing migraine headache. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain.
How Migrest Total Kit Tablet 1's Works
Storage
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
- Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
- Eat a balanced diet and avoid foods high in estrogen-like compounds.
- Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
- Eat a balanced diet rich in fruits, vegetables, whole grains, and healthy fats.
- Engage in regular moderate exercise, avoiding excessive strenuous activity.
- Practice relaxation techniques like deep breathing, meditation, or yoga to manage stress.
- Ensure adequate sleep and hydration.
- Track your menstrual cycle to monitor patterns and symptoms.
- Increase calorie intake and aim for a healthy energy balance.
- Prioritize healthy fats annd take omega-3 rich foods like fatty fish, avocado, nuts, and seeds.
- Eat complex carbohydrates like whole grains like brown rice, quinoa, whole wheat bread, and oats.
- Ensure adequate protein intake like lean protein sources like chicken, fish, beans, lentils, and tofu.
- Include calcium-rich foods such as dairy products like milk, yogurt, and fortified plant-based options.
- Consume vitamin D sources like fortified milk, fatty fish, or consider supplementation.
- Practice relaxation techniques like yoga, meditation, and deep breathing exercises to manage stress.
- Do moderate exercise and reduce intensity or duration to prevent hormonal disruption.
- Aim for 7-8 hours of restful sleep each night to help your body and mind recharge.
- Stay hydrated by drinking plenty of water.
- Maintain a healthy body weight through balanced diet and exercise.
- Consult a healthcare professional before making significant dietary changes, especially if suspecting a medical cause for amenorrhea.
- Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
- Reduced alcohol intake can enhance liver enzyme function.
- Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
- Liver function tests regularly can help manage increased levels of AST.
- Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
- Consume vitamin C-rich foods as they aid iron absorption.
- Limit tea, cocoa, and coffee as these can slow iron absorption.
- Exercise regularly; however, do not overdo it.
- Tell your doctor immediately if you experience shortness of breath after taking medication.
- Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
- Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
- For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
- Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
- Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
- Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
What if I have taken an overdose of Migrest Total Kit Tablet 1's
Drug Warnings
You can increase the efficacy of Migrest Total Kit Tablet 1's by taking a small meal or snacks frequently. Do not take Migrest Total Kit Tablet 1's if you are allergic to Migrest Total Kit Tablet 1's and other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Migrest Total Kit Tablet 1's. Inform your doctor if you have heart, kidney, and liver disease. Prolonged intake of Migrest Total Kit Tablet 1's may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking a higher dose. Migrest Total Kit Tablet 1's is not recommended in depression, shock, phenylketonuria, Parkinson's disease, breast cancer. Prolonged intake of Migrest Total Kit Tablet 1's may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack), urinary tract obstruction. This risk may be more likely in the elderly (those over 60 years old) or taking a higher dose.
Drug-Drug Interactions
Drug-Drug Interactions
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Coadministration of Migrest Total Kit Tab with Halofantrine can Increase the risk of irregular heart rhythm.
How to manage the interaction:
Although taking Migrest Total Kit Tab and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
Combining Mizolastine with Migrest Total Kit Tab can increase the risk or severity of irregular heart rhythms.
How to manage the interaction:
Although taking Migrest Total Kit Tab and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Migrest Total Kit Tab with Nefazodone can increase the blood levels of Migrest Total Kit Tab.
How to manage the interaction:
There may be a possibility of interaction between Migrest Total Kit Tab and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.
How to manage the interaction:
Although taking Migrest Total Kit Tab and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Migrest Total Kit Tab with Methadone can Increase the risk of irregular heart rhythm.
How to manage the interaction:
Although taking Migrest Total Kit Tab and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Migrest Total Kit Tab with Clarithromycin can increase the risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Migrest Total Kit Tab and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
Coadministration of Migrest Total Kit Tab with Citalopram can Increase the risk of irregular heart rhythm.
How to manage the interaction:
Although taking Migrest Total Kit Tab and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Migrest Total Kit Tab with Cisapride can increase the blood levels of Migrest Total Kit Tab.
How to manage the interaction:
There may be a possibility of interaction between Migrest Total Kit Tab and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
Coadministration of Migrest Total Kit Tab with Ketoconazole can Increase the risk of irregular heart rhythm.
How to manage the interaction:
Although taking Migrest Total Kit Tab and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Migrest Total Kit Tab with Toremifene can Increase the risk of irregular heart rhythm.
How to manage the interaction:
Although taking Migrest Total Kit Tab and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating overly- sweet food and include more salty food, especially if you have been vomiting.
- Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
- Include more cool beverages in your food like clear soup, flavoured gelatin, carbonated beverages. Also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas and acidity.
- Drink after or any other liquid at least 30 minutes after eating food.
- Avoid smoking and alcohol intake.
- Avoid chronic stress as it can raise your migraine pain. Try to enjoy and spending time with your friends to cope with stress and practice mindfulness techniques.
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Alcohol
Unsafe
Alcohol may increase the risk of tiredness and drowsiness with Migrest Total Kit Tablet 1's. If you do feel tired or drowsy whilst taking Migrest Total Kit Tablet 1's, avoid alcoholic drinks
Pregnancy
Unsafe
Migrest Total Kit Tablet 1's is not recommended during pregnancy. Consult your doctor before taking Migrest Total Kit Tablet 1's.
Breast Feeding
Unsafe
Migrest Total Kit Tablet 1's is not recommended during breastfeeding. Consult your doctor before taking Migrest Total Kit Tablet 1's.
Driving
Unsafe
Taking Migrest Total Kit Tablet 1's may cause dizziness, drowsiness, tiredness, or any visual disturbances; you must not drive or use machinery.
Liver
Caution
Migrest Total Kit Tablet 1's is to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
Caution
Migrest Total Kit Tablet 1's is to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
Safe if prescribed
Generally, Migrest Total Kit Tablet 1's is not recommended for children below 12 years with or without a doctor's consent. In case it has to be given, then the dose has to be adjusted and recommended by a child specialist only.
Heart
Caution
Migrest Total Kit Tablet 1's should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Migrest Total Kit Tablet 1's.
Geriatrics
Caution
Migrest Total Kit Tablet 1's should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Migrest Total Kit Tablet 1's.
FAQs
Migrest Total Kit Tablet 1's is used to treat migraine.
Migrest Total Kit Tablet 1's is a combination of three drugs, namely: Domperidone, flunarizine, and Paracetamol. Domperidone prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone –CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Flunarizine is a calcium channel blocker that works by preventing the narrowing of blood vessels in the head thereby preventing migraine headache. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain.
Some people may experience common side effects like weight gain, drowsiness, dryness in the mouth. Most of these side effects of Migrest Total Kit Tablet 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Talk to your doctor if you do not feel better even after taking Migrest Total Kit Tablet 1's for 14 days. Do not take Migrest Total Kit Tablet 1's for longer durations unless prescribed by the doctor.
It is best to avoid alcohol while taking Migrest Total Kit Tablet 1's as it can make damage to your liver.
Yes, Migrest Total Kit Tablet 1's is known to cause weight gain. So, do regular exercise and try to eat home-cooked food to avoid excessive weight gain.
You are recommended not to stop taking Migrest Total Kit Tablet 1's without consulting your doctor as stopping it suddenly can cause adverse effects. Therefore, continue taking Migrest Total Kit Tablet 1's for the duration prescribed and if you experience any difficulty while taking Migrest Total Kit Tablet 1's, consult your doctor so that the dose may be reduced gradually.
Yes, the use of Migrest Total Kit Tablet 1's can cause dry mouth. If this happens, drinking plenty of water and taking regular sips throughout the day can help. If you experience persistent dry mouth you are advised to consult your doctor.
Migraine attacks can be caused by stress, certain foods (like chocolate or cheese), hormonal changes, and poor sleep. Weather changes and strong smells may also play a role. Not drinking enough water or skipping meals can also trigger migraines.
You are not advised to take higher than recommended doses as Migrest Total Kit Tablet 1's may increase the risk of serious side effects. If your symptoms worsen and are not relieved by the recommended dose, consult your doctor for re-evaluation.
Store Migrest Total Kit Tablet 1's in a cool and dry place below 30°C. Protect from light. Keep it out of reach of children. Migrest Total Kit Tablet 1's should be disposed, by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.
Yes, Migrest Total Kit Tablet 1's may cause sleepiness. It is not necessary for everyone taking Migrest Total Kit Tablet 1's to experience this side effect. Therefore, avoid driving or operating heavy machinery if you feel sleepy after taking Migrest Total Kit Tablet 1's.
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Reference
- https://www.gosh.nhs.uk/medical-information-0/search-medical-conditions/medicines-information/flunarizine-prevent-migraine
- https://www.medicineindia.org/pharmacology-for-generic/3317/flunarizine-domperidone-paracetamol
- https://www.mims.com/india/drug/info/domperidone%20+%20paracetamol?type=full&mtype=generic
