Mistaurin Capsule 4's

Mistaurin Capsule belongs to the group of medicines called protein kinase inhibitors used to treat acute myeloid leukaemia (AML). It is sometimes, also used to treat aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), or mast cell leukaemia (MCL).

Mistaurin Capsule contains Midostaurin, which works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells.

Mistaurin Capsule may cause certain side effects such as nausea, vomiting, headache, fever, musculoskeletal pain, and upper abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen. Take Mistaurin Capsule as prescribed by your doctor.

Discontinue taking Mistaurin Capsule and inform your physician if you observe any allergic reactions. Inform the doctor about your health condition and medications to rule out any side effects. Do not take Mistaurin Capsule if you are pregnant or breastfeeding. This medicine is not recommended for children as safety and effectiveness have not been established.

Mistaurin Capsule is used in the treatment of Acute myeloid leukaemia (AML), aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), and mast cell leukaemia (MCL). The detailed uses of Mistaurin Capsule are as follows:

• Treatment of FLT3-Mutated Acute Myeloid Leukemia (AML): Mistaurin Capsule is used in combination with standard chemotherapy (cytarabine and daunorubicin) to treat newly diagnosed AML in adults who test positive for FLT3 mutations.
• Management of Advanced Systemic Mastocytosis (ASM): Mistaurin Capsule helps reduce the proliferation of abnormal mast cells in patients with aggressive systemic mastocytosis, improving symptoms and slowing disease progression.
• Therapy for Mast Cell Leukemia (MCL) and SM-AHN: Mistaurin Capsule is used for rare blood disorders like mast cell leukemia and systemic mastocytosis with associated hematologic neoplasm, targeting abnormal cell growth in bone marrow and blood.
• Tyrosine Kinase Inhibition Mechanism: Mistaurin Capsule works by blocking multiple kinases, including FLT3, which are involved in cancer cell growth and survival, making it effective against certain hematologic malignancies.

• Recommended to take Mistaurin Capsule with food to prevent stomach upset.
• Recommended to take twice daily or as advised by your doctor.
• Swallow the medicine as a whole with a glass of water.
• Do not crush, break, or chew it.

Mistaurin Capsule belongs to the group of medicines called protein kinase inhibitors used to treat acute myeloid leukaemia (AML) in patients who are FLT3 mutation-positive. It is also used to treat aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), or mast cell leukaemia (MCL). Mistaurin Capsule contains Midostaurin, which works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells.

Do not take Mistaurin Capsule if you are allergic to any of its components, if you are taking medicines used to treat tuberculosis (rifampicin), epilepsy (carbamazepine or phenytoin), prostate cancer (enzalutamide), or herbal products (St. John’s Wort) or if you are pregnant or breastfeeding. Inform the doctor if you have any infections, heart disorders, lung, kidney or liver diseases. Seek immediate medical attention if you experience symptoms of low white blood cell count (fever, sore throat, mouth ulcers), lung problems (fever, chest pain, cough with or without mucous, trouble breathing or shortness of breath), or heart problems (chest pain or discomfort, fainting, dizziness, light-headedness, shortness of breath, blue discolouration of your lips, hands or feet, or swelling of your lower limbs).