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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Mito 2 Injection is used to treat breast cancer, stomach cancer, cancer of the respiratory tract, and advanced cancer of the pancreas. It contains Mitomycin which works by stopping the cancer cells from dividing. In some cases, this medicine may cause side effects such as nausea, vomiting, hair loss, kidney disorders, fever, and lung disorders. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Composition :

MITOMYCIN-2MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Mito 2 Injection

Mito 2 Injection belongs to a group of medicines known as 'anti-cancer' used in cancer therapy. It is most effective in the treatment of advanced metastatic stomach cancer (stomach carcinoma), advanced and/or metastatic breast cancer (breast carcinoma), cancer of the respiratory tract (non-small cell bronchial carcinoma), and advanced cancer of the pancreas (pancreatic carcinoma). Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Cancer sometimes begins in one body part before spreading to other areas. This process is known as metastasis.

Mito 2 Injection contains Mitomycin, an anti-cancer medication that is cytotoxic (causes cell death). It works by inhibiting the genetic material's development (DNA) in a cell (cancer cell), thereby stopping cancer cells from dividing. As a result, cancer cell growth and spread stopped or slowed.

Healthcare professionals administer Mito 2 Injection. It is intended to be used as an injection or infusion into a blood vessel. Depending upon your medical condition, you are advised to take Mito 2 Injection for as long as your doctor has prescribed it for you. In some cases, you may experience certain common side effects such as nausea, vomiting, hair loss, kidney disorders, fever, and lung disorders. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Mito 2 Injection, inform your doctor if you have any infection because Mito 2 Injection may worsen the infection. Some patients may experience increased sensitivity to light while taking Mito 2 Injection, and avoiding prolonged exposure to sunlight is recommended. Inform your doctor if you are pregnant as Mito 2 Injection can cause harmful effects on the unborn baby. Both women and men using this Mito 2 Injection should use birth control to avoid pregnancy. You should not take this Mito 2 Injection during breastfeeding. Inform your doctor if you take Mito 2 Injection. Use the Mito 2 Injection with caution in elderly patients. Do not take live vaccines three months after your last chemotherapy. Before starting therapy, your doctor may recommend you undergo tests for lung, kidney, and liver function to exclude any diseases.

Uses of Mito 2 Injection

Treatment of Breast cancer, stomach cancer, cancer of the respiratory tract, and advanced cancer of the pancreas.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Mito 2 Injection will be administered by a nurse or doctor.• Do not self-administer

Medicinal Benefits

Mito 2 Injection belongs to the group of anti-cancer medicines containing Mitomycin. It works by inhibiting the genetic material's development (DNA) in a cell (cancer cell), thereby destroying quickly dividing cells. As a result, the growth and spread of cancer cells in stopped or slowed down.

How Mito 2 Injection Works

Mito 2 Injection contains Mitomycin, an anti-cancer medication that is cytotoxic (causes cell death). It works by inhibiting the genetic material's development (DNA) in a cell (cancer cell), thereby stopping cancer cells from dividing. As a result, cancer cell growth and spread stopped or slowed.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mito 2 Injection
  • Focus on consuming whole, unprocessed foods like fresh fruits, vegetables, and leafy greens.
  • Incorporate healthy fats like avocado, nuts, seeds, and olive oil into your diet.
  • Choose whole grains, lean protein sources, and vitamin C-rich foods like citrus fruits and berries.
  • Limit or avoid processed foods, excessive sugar, red meat, and alcohol.
  • Stay hydrated by drinking plenty of water.
  • Engage in gentle exercise like walking, swimming, or yoga to promote overall health.
  • Avoid strenuous activity, contact sports, and heavy lifting to minimize injury risk.
  • Practice stress management techniques like meditation, deep breathing, or relaxation exercises.
  • Aim for 7-8 hours of sleep each night to support immune function and overall well-being.
  • Consult your doctor before making significant dietary changes to ensure alignment with your treatment plan.
  • Monitor your symptoms and report any signs of bleeding or bruising to your healthcare provider.
  • Consider consulting a registered dietitian for a personalized meal plan tailored to your needs.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.

What if I have taken an overdose of Mito 2 Injection

Since Mito 2 Injection is given by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Before taking the Mito 2 Injection, inform your doctor if you have any active infection. Some patients may experience increased sensitivity to light while taking Mito 2 Injection and avoiding prolonged exposure to sunlight is recommended. Consult your doctor if you are pregnant as Mito 2 Injection can cause harmful effects on the unborn baby. Both women and men using this Mito 2 Injection should use birth control to avoid pregnancy. You should not take Mito 2 Injection during breastfeeding. Use the Mito 2 Injection with caution in elderly patients. Inform your doctor if you have impaired lung, kidney, or liver function, urinary bladder inflammation, or are undergoing radiation therapy. Mito 2 Injection is not recommended for use in children and adolescents.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Mito 2 Injection:
Using filgrastim together with Mito 2 Injection reduce the effects of filgrastim.

How to manage the interaction:
Co-administration of Filgrastim with Mito 2 Injection can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mito 2 Injection:
Using infliximab together with Mito 2 Injection may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infliximab and Mito 2 Injection, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, chills, diarrhoea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mito 2 Injection:
Using etanercept together with Mito 2 Injection may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Etanercept with Mito 2 Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Mito 2 Injection:
Using adalimumab together with Mito 2 Injection may increase the risk of developing serious infections.

How to manage the interaction:
Although taking Mito 2 Injection and Adalimumab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, or burning urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mito 2 Injection:
Using fingolimod together with Mito 2 Injection may increase the risk of serious infections.

How to manage the interaction:
Although taking Mito 2 Injection and Fingolimod together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, call your doctor immediately. Do not discontinue any medications without consulting a doctor.
MitomycinGolimumab
Severe
How does the drug interact with Mito 2 Injection:
Using Mito 2 Injection together with golimumab may increase the risk of serious infections.

How to manage the interaction:
Although taking Mito 2 Injection and Golimumab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call your doctor right away. Do not discontinue any medications without first consulting a doctor.
How does the drug interact with Mito 2 Injection:
Using leflunomide together with Mito 2 Injection may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Leflunomide with Mito 2 Injection can result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Mito 2 Injection:
Taking Fluorouracil with Mito 2 Injection has been associated with a condition known as hemolytic uremic syndrome (HUS) and using it with fluorouracil may increase that risk.

How to manage the interaction:
Although taking Mito 2 Injection and Fluorouracil together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without first consulting a doctor.
How does the drug interact with Mito 2 Injection:
Deferiprone can lower white blood cell count and combining it with Mito 2 Injection which can also affect white blood cells or bone marrow function may increase the risk.

How to manage the interaction:
Although taking Mito 2 Injection and Deferiprone together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, call a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mito 2 Injection:
Using thalidomide together with Mito 2 Injection can increase the risk of dangerous blood clots.

How to manage the interaction:
Although taking thalidomide and Mito 2 Injection together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult a doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your dialy diet.
  • Avoid fast, fried, processed meats, refined carbs, and added sugars.
  • Get optimal sleep, and rest well.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC
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Alcohol

Caution

You are recommended to avoid alcohol intake while taking Mito 2 Injection to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Mito 2 Injection should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Mito 2 Injection and at least six months afterwards. Discuss with your doctor any concerns regarding this.

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Breast Feeding

Unsafe

Mito 2 Injection should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

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Driving

Caution

Mito 2 Injection may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Inform your doctor before receiving the Mito 2 Injection if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Mito 2 Injection if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Mito 2 Injection should not be used by children, as the efficacy and safety have not been established.

Have a query?

FAQs

Mito 2 Injection is used to treat breast cancer, stomach cancer, cancer of the respiratory tract, and advanced cancer of the pancreas.

Mito 2 Injection contains Mitomycin is an anti-cancer medication that interferes with the growth of genetic material (DNA) of the cancer cells. This slows the growth of cancer cells and eventually kills them.

Yes, Mito 2 Injection may change the results of blood tests and other laboratory tests. Inform the person doing the tests that you are taking Mito 2 Injection as regular monitoring of liver and kidney functions tests, electrolyte level, and blood cells is required.

Mito 2 Injection might affect the fertility (ability to have children) in both men and women. You may not be able to become pregnant or father a child after treatment with Mito 2 Injection. However, it is essential to talk to your doctor before starting treatment with Mito 2 Injection if you think you may want to have a baby in the future.

The most common sign of lung cancer is a cough that lasts long and gets worse with time. Sometimes, a patient may notice blood in the cough. Chest pain is also a sign of lung cancer followed by coughing. However, symptoms/signs vary from person to person.

Your doctor will decide the number of treatment cycles and the frequency of Mito 2 Injection to be taken, depending on the type and stage of cancer treated.

While taking Mito 2 Injection, make sure you visit your doctor at all the appointments to ensure that treatment is working. Regular monitoring of blood and urine tests, weight checks are required. An effective way of contraception should be used by both men and women while taking Mito 2 Injection.

Yes, you might become more sensitive to sunlight while taking Mito 2 Injection, so it is important to protect your skin with a high sun protection factor (SPF) while going out as it can lead to a skin rash if you are not using a strong SPF.

Mito 2 Injection can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.

Do not stop taking Mito 2 Injection without talking to your doctor, even if you feel better. Stopping too soon can make the medication less effective and even lead to a recurrence. Your doctor will assess your progress and decide when it's safe to stop treatment. Always follow the doctor’s instructions.

The common side effects of Mito 2 Injection may include nausea, vomiting, hair loss, kidney disorders, fever, and lung disorders. You are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - MIT0066

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