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compositionComposition:MITOMYCIN-2MG
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Mitomycin C 2 mg Injection 2 ml is used to treat breast cancer, stomach cancer, cancer of the respiratory tract, and advanced cancer of the pancreas. It contains Mitomycin which works by stopping the cancer cells from dividing. In some cases, this medicine may cause side effects such as nausea, vomiting, hair loss, kidney disorders, fever, and lung disorders. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MITOMYCIN-2MG

Manufacturer/Marketer :

Biochem Pharmaceutical Industries Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Mitomycin C 2 mg Injection 2 ml

Mitomycin C 2 mg Injection 2 ml is a specialised injectable medication used primarily to treat various types of cancers, including stomach, pancreatic, and bladder cancers. It functions as a chemotherapy tool designed to stop abnormal cells from growing and dividing in the body. Because of its strength, it is carefully managed by medical professionals in a clinic or hospital setting.

This medication is usually given in cycles, and staying consistent with your treatment schedule is vital for its success. Since it is injected directly into a vein or the bladder, you do not need to worry about taking it with or without food, but staying well-hydrated is highly recommended. Making simple lifestyle adjustments, such as planning light activities and eating gentle, nutrient-rich foods, can help support your body during therapy.

While this medicine is effective, it can cause common side effects like nausea, tiredness, and low blood cell counts. It is crucial to monitor your body closely and contact your doctor immediately if you experience signs of infection, unexpected bruising, or breathing difficulties. Your healthcare team is trained to help you manage these side effects safely.

Do not take this if you have a history of severe bleeding disorders, extremely low blood cell levels, or if you have had a severe allergic reaction to it in the past. Talk to your doctor before starting therapy if you have underlying kidney problems, as this condition may require special monitoring. Your medical team will carefully evaluate your health history to ensure this treatment is safe for you.

Mitomycin C 2 mg Injection 2 ml can interact with other cancer treatments, radiation therapy, and live vaccines, which can increase your risk of severe side effects or infections. If you are pregnant, breastfeeding, or planning a family, talk to your doctor, as this medicine can harm an unborn baby. Elderly individuals should also consult their doctor, as they may be more sensitive to the side effects of this treatment.

Uses of Mitomycin C 2 mg Injection 2 ml

Mitomycin C 2 mg Injection 2 ml is used to treat various types of cancers, including stomach, pancreatic, and bladder cancers. The detailed uses of Mitomycin C 2 mg Injection 2 ml are as follows:

  • Stomach cancer: Mitomycin C 2 mg Injection 2 ml helps by targeting and stopping the rapidly dividing cancer cells within the stomach lining, slowing the progression of the disease.
  • Pancreatic cancer: Mitomycin C 2 mg Injection 2 ml helps by working in combination with other treatments to arrest tumour growth and manage advanced stages of pancreatic cancer.
  • Bladder cancer: Mitomycin C 2 mg Injection 2 ml helps when injected directly into the bladder (intravesical therapy) to target surface-level tumours and significantly lower the risk of the cancer returning after surgery.

Key Benefits

Mitomycin C 2 mg Injection 2 ml offers significant clinical benefits for individuals facing complex cancer diagnoses. By disrupting the growth cycle of cancer cells, it helps control the spread of the disease and can lead to a reduction in tumour size.

  • Prevents cancer recurrence: When used in the bladder, it acts directly on any remaining cancer cells, providing local protection and preventing the tumour from coming back.
  • Provides targeted therapy options: It serves as a vital treatment option when other standard first-line therapies may not have been fully effective.
  • Supports combined treatment plans: It works synergistically with other chemotherapy agents and radiation to improve overall treatment outcomes.
Side effects of Mitomycin C 2 mg Injection 2 ml
  • Focus on consuming whole, unprocessed foods like fresh fruits, vegetables, and leafy greens.
  • Incorporate healthy fats like avocado, nuts, seeds, and olive oil into your diet.
  • Choose whole grains, lean protein sources, and vitamin C-rich foods like citrus fruits and berries.
  • Limit or avoid processed foods, excessive sugar, red meat, and alcohol.
  • Stay hydrated by drinking plenty of water.
  • Engage in gentle exercise like walking, swimming, or yoga to promote overall health.
  • Avoid strenuous activity, contact sports, and heavy lifting to minimize injury risk.
  • Practice stress management techniques like meditation, deep breathing, or relaxation exercises.
  • Aim for 7-8 hours of sleep each night to support immune function and overall well-being.
  • Consult your doctor before making significant dietary changes to ensure alignment with your treatment plan.
  • Monitor your symptoms and report any signs of bleeding or bruising to your healthcare provider.
  • Consider consulting a registered dietitian for a personalized meal plan tailored to your needs.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Mitomycin C 2 mg Injection 2 ml will be administered by a nurse or doctor.
  • Do not self-administer.

How Mitomycin C 2 mg Injection 2 ml Works

Mitomycin C 2 mg Injection 2 ml contains mitomycin, which is an antitumor antibiotic that acts directly on the genetic material of rapidly dividing cells. Once it is injected into the body, it enters the cancer cells and binds tightly to their DNA strands. By linking these strands together, it prevents the cells from copying their DNA, which is a necessary step for them to multiply. Because cancer cells divide much faster than most healthy cells, they are highly sensitive to this DNA disruption. Without the ability to replicate their genetic blueprint, the cancer cells stop growing and eventually die. This targeted mechanism helps to control the spread of tumors while preserving as many healthy surrounding tissues as possible.
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Alcohol

Caution

You are recommended to avoid alcohol intake while taking Mitomycin C 2 mg Injection 2 ml to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Mitomycin C 2 mg Injection 2 ml should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Mitomycin C 2 mg Injection 2 ml and at least six months afterwards. Discuss with your doctor any concerns regarding this.

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Breast Feeding

Unsafe

Mitomycin C 2 mg Injection 2 ml should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

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Driving

Caution

Mitomycin C 2 mg Injection 2 ml may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Inform your doctor before receiving the Mitomycin C 2 mg Injection 2 ml if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Mitomycin C 2 mg Injection 2 ml if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Mitomycin C 2 mg Injection 2 ml should not be used by children, as the efficacy and safety have not been established.

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Heart

Caution

Mitomycin C 2 mg Injection 2 ml should be administered with caution, especially if you have a history of heart problems. Please inform your doctor about any existing heart problems before receiving Mitomycin C 2 mg Injection 2 ml.

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Geriatrics

Caution

Mitomycin C 2 mg Injection 2 ml should be administered with caution in elderly patients due to an increased risk of side effects. Dose adjustment may be required based on their health condition.

What if I have taken an overdose of Mitomycin C 2 mg Injection 2 ml

Since a trained medical professional prepares and injects this medication, an overdose is extremely rare. However, if you suspect an error has occurred or experience severe, sudden side effects after your session, seek emergency medical help immediately.

Diet & Lifestyle Advise

  • Stay highly hydrated: Drink at least 8 to 10 glasses of water daily, especially on treatment days. This helps your kidneys process and flush the medication out of your system.
  • Protect your immune system: Avoid crowded places and individuals who are sick. Wash your hands frequently with soap and water to lower your risk of contracting infections.
  • Eat small, frequent meals: To manage nausea and maintain your energy, eat five or six small, bland meals throughout the day instead of three large ones.
  • Practice toilet safety: If you receive bladder treatments, sit down to urinate to prevent splashing, and wash your hands and genital area thoroughly after urinating to prevent skin irritation.
  • Prioritise rest: Allow your body time to recover by scheduling regular rest periods throughout the day, especially in the 48 hours following your treatment.
health query

Have a query?

How Soon It Starts Working

The time required for Mitomycin C 2 mg Injection 2 ml to start to work: The time required for Mitomycin C 2 mg Injection 2 ml to show its action is unknown. The time for which the effects of Mitomycin C 2 mg Injection 2 ml last: The duration of action for Mitomycin C 2 mg Injection 2 ml is clinically unknown.

What if you forget to take Mitomycin C 2 mg Injection 2 ml

Because this medication is injected by a healthcare provider in a clinical setting, it is highly unlikely that you will miss a dose. If you miss or have to postpone a scheduled appointment, contact your treatment clinic immediately to reschedule your session.

Storage

•Once the powder is mixed into a liquid solution, it must be used within the clinically recommended timeframe or stored in a refrigerator at 2°C to 8°C (36°F to 46°F) and kept away from freezing conditions.

Drug Warnings

  • Report any burning immediately: If you feel any pain, burning, or stinging at the injection site during your infusion, tell your medical team right away. If the medicine leaks into surrounding tissues, it can cause severe tissue damage.
  • Monitor your temperature daily: Keep a reliable thermometer at home and check your temperature regularly. A fever during chemotherapy can be a sign of a serious, life-threatening infection.
  • Do not get live vaccines: Avoid immunisations that contain live viruses while using this medication, as your immune system may not be strong enough to protect you.
  • Use reliable contraception: Both men and women must use highly effective birth control during treatment and for several months afterwards to prevent pregnancy, as this medication can cause severe birth defects.
  • Check your skin: Regularly inspect your skin for any unusual red or purple spots, which could indicate a drop in your platelet count.

Drug-Drug Interactions

verifiedApollotooltip
  • Other chemotherapy drugs: May increase the risk of severe bone marrow suppression and low blood cell counts when combined with other cancer treatments.
  • Live vaccines: May increase the risk of severe, vaccine-induced infections due to a weakened immune system.
MitomycinFluorouracil
Severe
MitomycinGolimumab
Severe

Drug-Drug Interactions

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MitomycinFluorouracil
Severe
How does the drug interact with Mitomycin C 2 mg Injection 2 ml C 2 mg Injection 2 ml:
Taking Fluorouracil with Mitomycin C 2 mg Injection 2 ml has been associated with a condition known as hemolytic uremic syndrome (HUS) and using it with fluorouracil may increase that risk.

How to manage the interaction:
Although taking Mitomycin C 2 mg Injection 2 ml and Fluorouracil together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without first consulting a doctor.
MitomycinGolimumab
Severe
How does the drug interact with Mitomycin C 2 mg Injection 2 ml C 2 mg Injection 2 ml:
Using Mitomycin C 2 mg Injection 2 ml together with golimumab may increase the risk of serious infections.

How to manage the interaction:
Although taking Mitomycin C 2 mg Injection 2 ml and Golimumab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call your doctor right away. Do not discontinue any medications without first consulting a doctor.
MitomycinLeflunomide
Severe
How does the drug interact with Mitomycin C 2 mg Injection 2 ml C 2 mg Injection 2 ml:
Using leflunomide together with Mitomycin C 2 mg Injection 2 ml may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Leflunomide with Mitomycin C 2 mg Injection 2 ml can result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
MitomycinAdalimumab
Severe
How does the drug interact with Mitomycin C 2 mg Injection 2 ml C 2 mg Injection 2 ml:
Using adalimumab together with Mitomycin C 2 mg Injection 2 ml may increase the risk of developing serious infections.

How to manage the interaction:
Although taking Mitomycin C 2 mg Injection 2 ml and Adalimumab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, or burning urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MitomycinFingolimod
Severe
How does the drug interact with Mitomycin C 2 mg Injection 2 ml C 2 mg Injection 2 ml:
Using fingolimod together with Mitomycin C 2 mg Injection 2 ml may increase the risk of serious infections.

How to manage the interaction:
Although taking Mitomycin C 2 mg Injection 2 ml and Fingolimod together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, call your doctor immediately. Do not discontinue any medications without consulting a doctor.
MitomycinInfliximab
Severe
How does the drug interact with Mitomycin C 2 mg Injection 2 ml C 2 mg Injection 2 ml:
Using infliximab together with Mitomycin C 2 mg Injection 2 ml may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infliximab and Mitomycin C 2 mg Injection 2 ml, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, chills, diarrhoea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee. Do not discontinue any medications without consulting a doctor.
MitomycinEtanercept
Severe
How does the drug interact with Mitomycin C 2 mg Injection 2 ml C 2 mg Injection 2 ml:
Using etanercept together with Mitomycin C 2 mg Injection 2 ml may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Etanercept with Mitomycin C 2 mg Injection 2 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor’s advice.
MitomycinBaricitinib
Severe
How does the drug interact with Mitomycin C 2 mg Injection 2 ml C 2 mg Injection 2 ml:
Using baricitinib together with Mitomycin C 2 mg Injection 2 ml may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Mitomycin C 2 mg Injection 2 ml if prescribed by the doctor. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhoea, sore throat, muscle aches, breathing difficulty, blood in phlegm, red or inflamed skin, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
MitomycinDeferiprone
Severe
How does the drug interact with Mitomycin C 2 mg Injection 2 ml C 2 mg Injection 2 ml:
Deferiprone can lower white blood cell count and combining it with Mitomycin C 2 mg Injection 2 ml which can also affect white blood cells or bone marrow function may increase the risk.

How to manage the interaction:
Although taking Mitomycin C 2 mg Injection 2 ml and Deferiprone together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, call a doctor immediately. Do not discontinue any medications without consulting a doctor.
MitomycinThalidomide
Severe
How does the drug interact with Mitomycin C 2 mg Injection 2 ml C 2 mg Injection 2 ml:
Using thalidomide together with Mitomycin C 2 mg Injection 2 ml can increase the risk of dangerous blood clots.

How to manage the interaction:
Although taking thalidomide and Mitomycin C 2 mg Injection 2 ml together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult a doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Mitomycin C 2 mg Injection 2 ml when used as directed.

No clinically significant drug interactions are known with Mitomycin C 2 mg Injection 2 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Mitomycin C 2 mg Injection 2 ml is used to treat breast cancer, stomach cancer, cancer of the respiratory tract, and advanced cancer of the pancreas.
Mitomycin C 2 mg Injection 2 ml contains Mitomycin is an anti-cancer medication that interferes with the growth of genetic material (DNA) of the cancer cells. This slows the growth of cancer cells and eventually kills them.
Yes, Mitomycin C 2 mg Injection 2 ml may change the results of blood tests and other laboratory tests. Inform the person doing the tests that you are taking Mitomycin C 2 mg Injection 2 ml as regular monitoring of liver and kidney functions tests, electrolyte level, and blood cells is required.
Mitomycin C 2 mg Injection 2 ml might affect the fertility (ability to have children) in both men and women. You may not be able to become pregnant or father a child after treatment with Mitomycin C 2 mg Injection 2 ml. However, it is essential to talk to your doctor before starting treatment with Mitomycin C 2 mg Injection 2 ml if you think you may want to have a baby in the future.
The most common sign of lung cancer is a cough that lasts long and gets worse with time. Sometimes, a patient may notice blood in the cough. Chest pain is also a sign of lung cancer followed by coughing. However, symptoms/signs vary from person to person.
While taking Mitomycin C 2 mg Injection 2 ml, make sure you visit your doctor at all the appointments to ensure that treatment is working. Regular monitoring of blood and urine tests, weight checks are required. An effective way of contraception should be used by both men and women while taking Mitomycin C 2 mg Injection 2 ml.
Yes, you might become more sensitive to sunlight while taking Mitomycin C 2 mg Injection 2 ml, so it is important to protect your skin with a high sun protection factor (SPF) while going out as it can lead to a skin rash if you are not using a strong SPF.
Mitomycin C 2 mg Injection 2 ml can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.
Do not stop taking Mitomycin C 2 mg Injection 2 ml without talking to your doctor, even if you feel better. Stopping too soon can make the medication less effective and even lead to a recurrence. Your doctor will assess your progress and decide when it's safe to stop treatment. Always follow the doctor’s instructions.
The common side effects of Mitomycin C 2 mg Injection 2 ml may include nausea, vomiting, hair loss, kidney disorders, fever, and lung disorders. You are advised to talk to your doctor if you experience these side effects persistently.
This medication is injected by a healthcare professional in a clinic or hospital. Depending on your specific condition, it is either injected into a vein (intravenously) or placed directly into the bladder through a catheter (intravesically). Talk to your doctor for more details about your specific administration method.
Yes, temporary hair thinning or hair loss is a common side effect of this treatment. Your hair will typically begin to grow back after your therapy cycles are fully completed. Talk to your doctor if you have concerns about managing hair loss.
You must tell your nurse or doctor immediately if you feel any burning, pain, or coldness around the injection site. This could mean the liquid is leaking out of the vein, which requires immediate medical action to prevent tissue damage. Talk to your doctor if you experience any lingering pain.
You should avoid receiving live vaccines during your treatment, as your immune system is weakened and you could develop a severe infection from the vaccine. Standard, non-live vaccines may be safe but might not work as effectively. Talk to your doctor before scheduling any vaccines.
No, this medication is not safe for use during pregnancy as it can cause serious harm or birth defects to an unborn baby. Both men and women should use highly effective birth control during treatment and for several months after stopping. Talk to your doctor immediately if you suspect you are pregnant.
This medication can temporarily lower your bone marrow's ability to produce red blood cells, white blood cells, and platelets. This can make you feel tired, increase your risk of infections, and make you bruise or bleed more easily. Talk to your doctor if you notice any unusual physical changes or signs of infection.
You should avoid or severely limit alcohol while undergoing this treatment, as alcohol can strain your liver and kidneys and worsen side effects like nausea and fatigue. Talk to your doctor about what is safe for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

BIOCHEM PHARMA, LG 113 / A, Xth Central Mall, Mahavir Nagar, 90ft Road, Next to D Mart, Kandivali - West, Mumbai - 400067.
Other Info - MIT0010
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