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compositionComposition:AMOXYCILLIN-400MG+CLAVULANIC ACID-57MG
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MOX CLAV DS 457MG TABLET is used to treat bacterial infections, including ear, sinus, respiratory tract, urinary tract, skin, soft tissue, dental, joint and bone infections. It works by killing the infection-causing bacteria. In some cases, this medicine may cause side effects such as vomiting, nausea, and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMOXYCILLIN-400MG+CLAVULANIC ACID-57MG

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About MOX CLAV DS 457MG TABLET

MOX CLAV DS 457MG TABLET is used to treat bacterial infections in the body that affect the skin, soft tissues, lungs, ears, urinary tract, and nasal sinuses. It should be mentioned that viral infections like the flu and the common cold are not treated by this medication.

MOX CLAV DS 457MG TABLET consists of Amoxycillin and Clavulanic acid. This medicine works by destroying the outer protein layer, thereby killing the bacteria (bactericidal action). As a result, it helps treat infection and reduce the further spread of infection. MOX CLAV DS 457MG TABLET does not work against infections caused by viruses, including colds and flu.

Not everyone who is taking MOX CLAV DS 457MG TABLET will get these side effects. The common side effects of MOX CLAV DS 457MG TABLET include vomiting, nausea, and diarrhoea. Everyone may not experience the above side effects. In case of any discomfort, speak with a doctor.

You can take MOX CLAV DS 457MG TABLET with food to avoid any stomach upset. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your medicine based on your medical condition. It is always important to complete your treatment course for better results.

Before starting MOX CLAV DS 457MG TABLET, please inform your doctor if you have any allergy (against any antibiotic) or any other components. Do not take MOX CLAV DS 457MG TABLET on your own as it may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections. MOX CLAV DS 457MG TABLET is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor if you are pregnant or breadfeeding before taking MOX CLAV DS 457MG TABLET.

Uses of MOX CLAV DS 457MG TABLET

MOX CLAV DS 457MG TABLET is used to treat Bacterial Infections. The detailed uses of MOX CLAV DS 457MG TABLET are as follows:

  • Bacterial Infections: MOX CLAV DS 457MG TABLET helps treat bacterial illnesses, including pneumonia and bronchitis. The composition of MOX CLAV DS 457MG TABLET improves efficacy against resistant microorganisms.
  • Sinusitis: MOX CLAV DS 457MG TABLET treats bacterial sinus infections by lowering inflammation and cleaning them.
  • Urinary Tract Infections (UTIs): MOX CLAV DS 457MG TABLET treats urinary tract infections caused by susceptible bacteria and provides broad-spectrum protection.
  • Skin and Soft Tissue Infection: MOX CLAV DS 457MG TABLET is also prescribed for treating skin and soft tissue infections, such as cellulitis and bite wounds, by its antibacterial effects to speed up the healing process.
  • Otitis Media: MOX CLAV DS 457MG TABLET helps to treat middle ear infections.
  • Pneumonia: MOX CLAV DS 457MG TABLET is also involved in treating pneumonia by efficiently fighting against the microorganisms that cause the condition.

Key Benefits

  • MOX CLAV DS 457MG TABLET is a broad-spectrum antibiotic that covers a very wide range of bacterial infections.
  • MOX CLAV DS 457MG TABLET has Clavulanic acid, which protects amoxycillin from getting destroyed by the bacterial enzyme, thus increasing its efficacy.
  • MOX CLAV DS 457MG TABLET helps overcome antibiotic resistance in bacteria that is caused by the enzyme beta-lactamase.
  • MOX CLAV DS 457MG TABLET is an effective medicine used in multiple infections like ear infections (acute otitis media), bronchitis, pneumonia, urinary tract infections, skin infections, etc.
Side effects of Mox Clav Ds 457mg Tablet
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Managing Medication-Triggered Moniliasis (a yeast infection): A Step-by-Step Guide:
  • If you experience symptoms like itching, burning, redness, or discharge after taking medication, consult your doctor immediately and share your symptoms, medication regimen, and medical history.
  • Your doctor will assess your medication regimen to determine if it's contributing to the moniliasis and identify the best course of action to manage your condition.
  • Your doctor may prescribe antifungal medications or recommend other treatments to help clear up the infection. They may also suggest self-care measures to help manage symptoms and prevent future infections.
  • If your condition doesn't improve or persists, consult your doctor and report it. Your doctor will assess your progress, adjust your treatment plan, and provide advice to ensure the best outcome.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
  • Eat fiber-rich foods like broccoli, cauliflower, leafy greens, and Brussels sprouts.
  • Limit sugar and refined carbs like avoid sugary drinks, white bread, and processed foods.
  • Choose lean protein sources like chicken, fish, and tofu.
  • Choose low-sugar fruits like berries, citrus fruits, and apples in moderation.
  • Maintain good hygiene and keep affected areas clean and dry.
  • Wear breathable clothing to reduce moisture.
  • Consider natural antifungal agents like coconut oil, tea tree oil, and garlic (consult a healthcare professional before use).

Directions for Use

  • MOX CLAV DS 457MG TABLET can be taken with food to avoid stomach upset.
  • It is usually taken every 8-12 hours or as prescribed by your doctor.
  • Swallow MOX CLAV DS 457MG TABLET as a whole with a glass of water.
  • Do not crush, chew, or break it.

How MOX CLAV DS 457MG TABLET Works

MOX CLAV DS 457MG TABLET consists of two medicines: Amoxycillin and Clavulanic acid. Amoxycillin acts by destroying the outer protein layer, thereby killing the bacteria (bactericidal action). Clavulanic acid inhibits the enzyme beta-lactamase, which prevents bacteria from destroying the efficacy of amoxycillin. As a result, the action of Clavulanic acid allows Amoxycillin to work better and kill the bacteria. MOX CLAV DS 457MG TABLET does not work against infections caused by viruses, including colds and flu.
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Alcohol

Caution

Avoid consumption of alcohol during the treatment with MOX CLAV DS 457MG TABLET as it may worsen the side effects like dizziness.

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Pregnancy

Consult your doctor

If you are pregnant, consult your doctor before taking MOX CLAV DS 457MG TABLET. Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

This medication passes into breast milk. If you are a nursing mother, consult your doctor before taking MOX CLAV DS 457MG TABLET. Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

MOX CLAV DS 457MG TABLET may cause dizziness in some people, so it may affect your ability to drive. Avoid driving or operating machines until you are alert after taking MOX CLAV DS 457MG TABLET.

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Liver

Caution

MOX CLAV DS 457MG TABLET to be taken with caution if you have a history of liver conditions. Your doctor may adjust the dose if necessary based on your condition.

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Kidney

Caution

MOX CLAV DS 457MG TABLET to be taken with caution, especially if you have a history of kidney conditions. Your doctor may adjust the dose if necessary based on your condition.

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Children

Consult your doctor

Please consult the doctor. Your child's doctor will decide the dosage of this medicine depending on the weight and the severity of the infection.

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Heart

Consult your doctor

Limited information is available. Please consult your doctor.

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Geriatrics

Caution

The use of MOX CLAV DS 457MG TABLET in elderly patients may increase the risk of serious side effects.

What if I have taken an overdose of MOX CLAV DS 457MG TABLET

Take MOX CLAV DS 457MG TABLET only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms may include nausea, vomiting, diarrhoea, stomach pain, drowsiness, skin rash, hyperactivity, and decreased urination. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics.
  • Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Probiotics should be taken after taking a full course of MOX CLAV DS 457MG TABLET in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea.
  • Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
  • Avoid alcoholic beverages with MOX CLAV DS 457MG TABLET as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the MOX CLAV DS 457MG TABLET in fighting off infections.
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How Soon It Starts Working

The time required for MOX CLAV DS 457MG TABLET to start to work: MOX CLAV DS 457MG TABLET starts to show its action within 1 to 2 hours of administration. The time for which the effects of MOX CLAV DS 457MG TABLET last: MOX CLAV DS 457MG TABLET effect lasts for 8 to 12 hours.

What if you forget to take MOX CLAV DS 457MG TABLET

If you miss a dose of MOX CLAV DS 457MG TABLET, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep MOX CLAV DS 457MG TABLET out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take MOX CLAV DS 457MG TABLET if you have an allergy to MOX CLAV DS 457MG TABLET, penicillin or cephalosporin class of antibiotics. Also, if you experience any allergic symptoms, including rash, swelling of the face/lips/throat, difficulty breathing, or chest tightness after taking $ name, immediately contact your doctor. 
  • People with liver diseases or jaundice (yellowing of skin/eyes) should not take MOX CLAV DS 457MG TABLET, as it can severely affect the liver. Inform your doctor if you have any kidney or heart disease before taking MOX CLAV DS 457MG TABLET.
  • The dose of MOX CLAV DS 457MG TABLET can vary depending on your condition and the severity of the infection. 
  • Additionally, it is recommended to complete the course of medicine even if you feel better, as it is an antibiotic, and leaving it incomplete may lead to a severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Caution should be exercised when MOX CLAV DS 457MG TABLET is administered in combination with gout medicine (allopurinol, probenecid), blood thinners (warfarin), anticancer, or anti-arthritis drug (methotrexate), and drug to prevent organ transplant (mycophenolate mofetil).

Drug-Food Interaction: Avoid taking eating high-fat meals as this may make it harder for your body to absorb MOX CLAV DS 457MG TABLET.

Drug-Disease Interaction: People affected with liver disease (like jaundice), glandular fever (viral infection with fever and sore throat), or colitis (bowel disease that affects the large intestine, causing irritation, inflammation, and ulcers in the colon) should not take MOX CLAV DS 457MG TABLET.

Clavulanic acid + AmoxicillinMethotrexate
Severe
Clavulanic acid + AmoxicillinCholera, live attenuated
Severe

Drug-Drug Interactions

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Clavulanic acid + AmoxicillinMethotrexate
Severe
How does the drug interact with Mox Clav Ds 457mg Tablet:
Co-administration of methotrexate with Mox Clav Ds 457mg Tablet can increase the levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Mox Clav Ds 457mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, pale skin, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, Consult a doctor immediately. Do not stop using medications without a doctor's advice.
Clavulanic acid + AmoxicillinCholera, live attenuated
Severe
How does the drug interact with Mox Clav Ds 457mg Tablet:
Co-administration of Mox Clav Ds 457mg Tablet and Cholera vaccine, live attenuated may reduce the activity of the vaccine.

How to manage the interaction:
Taking Mox Clav Ds 457mg Tablet and Cholera vaccine, live attenuated together can lead to an interaction, it can be taken if prescribed by the doctor. It is advised to take cholera vaccine, live at least 14 days after stopping Mox Clav Ds 457mg Tablet dose. Do not discontinue the medication without consulting a doctor.
Clavulanic acid + AmoxicillinDoxycycline
Severe
How does the drug interact with Mox Clav Ds 457mg Tablet:
Co-administration of Mox Clav Ds 457mg Tablet with doxycycline may reduce the effectiveness of amoxicillin.

How to manage the interaction:
Although there is a possible interaction between Mox Clav Ds 457mg Tablet and Doxycycline, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
Clavulanic acid + AmoxicillinBCG vaccine
Severe
How does the drug interact with Mox Clav Ds 457mg Tablet:
Co-administration of BCG vaccine with Mox Clav Ds 457mg Tablet may reduce the action of BCG vaccine.

How to manage the interaction:
Taking BCG vaccine with Mox Clav Ds 457mg Tablet can lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- INFECTIVES]

FAQs

MOX CLAV DS 457MG TABLET is used to prevent middle ear and sinus infections, throat or lung respiratory tract infections, urinary tract infections, skin infections, soft tissue infections, dental infections, and joint and bone infections.
MOX CLAV DS 457MG TABLET contains Amoxycillin and Clavulanic acid. Amoxycillin works by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thus it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of amoxycillin against the bacteria. Together, MOX CLAV DS 457MG TABLET helps in treating bacterial infections.
MOX CLAV DS 457MG TABLET is known to cause stomach upset, indigestion, nausea, and diarrhea. To avoid these side effects, please take MOX CLAV DS 457MG TABLET with a meal. Also, MOX CLAV DS 457MG TABLET should be taken at evenly spaced intervals to avoid any unpleasant side effects and for best results.
Generally, the penicillin group of antibiotics is not advised to be taken with methotrexate, which is used for conditions like psoriasis, rheumatoid arthritis, etc. They may cause unpleasant side effects when taken together. However, MOX CLAV DS 457MG TABLET is relatively safer to take with methotrexate, but only if prescribed by the doctor. It is best to discuss with your doctor about using the two medicines together, who may weigh the pros and cons and decide what is best for you.
Usually, MOX CLAV DS 457MG TABLET does not cause jaundice. But sometimes, it can cause jaundice in elderly people who have been taking the medication for a prolonged time. Please consult your doctor immediately if you notice any yellowing of the skin/eyes.
MOX CLAV DS 457MG TABLET does not treat a viral infection like the flu or a common cold. It is best to consult the doctor to know if you need MOX CLAV DS 457MG TABLET for your condition.
Yes, after taking MOX CLAV DS 457MG TABLET, you may have diarrhea. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration). Do not take anti-diarrhea medicine on your own; consult your doctor if the condition worsens.
MOX CLAV DS 457MG TABLET is not known to reduce the efficacy of birth control pills and emergency contraceptive pills. However, if you develop diarrhea or vomiting due to MOX CLAV DS 457MG TABLET, you are recommended to use other contraceptive methods such as condoms along with contraceptives to avoid unwanted pregnancies. Discuss with your doctor if you have any concerns regarding using MOX CLAV DS 457MG TABLET and your birth control pills.
MOX CLAV DS 457MG TABLET may show its effect 1.5 hours after taking the medicine. However, clinical improvement may be noticed after 48 hours.
MOX CLAV DS 457MG TABLET should be taken for the duration prescribed by the doctor based on your condition. Usually, it is taken every 8-12 hours.
MOX CLAV DS 457MG TABLET contains amoxicillin and clavulanic acid used to treat bacterial infections of the ear, sinus, respiratory tract, urinary tract, skin, soft tissue, dental, joints and bones.
Yes, MOX CLAV DS 457MG TABLET is safe to use if prescribed by the doctor.
MOX CLAV DS 457MG TABLET should not be used if you are allergic to any of its components or if you had jaundice or liver problems when taking an antibiotic.
Do not exceed the recommended dose of MOX CLAV DS 457MG TABLET as it might cause stomach upset or convulsions. Take MOX CLAV DS 457MG TABLET only as advised by the doctor.
Store MOX CLAV DS 457MG TABLET at room temperature (below 25°C). Keep it out of sight and reach of children. To help protect the environment, avoid throwing away any medicines via wastewater or household waste. Ask your pharmacist regarding the disposal of medicines.
To treat your infection effectively, continue taking MOX CLAV DS 457MG TABLET for the prescribed duration even if your symptoms are relieved.
MOX CLAV DS 457MG TABLET may cause an allergic reaction like skin rash, vasculitis (inflammation of blood vessels), angioedema (swelling), and difficulty breathing. Consult the doctor if you experience these symptoms.
No, MOX CLAV DS 457MG TABLET does not cause drowsiness. Sometimes, it might cause dizziness as an uncommon side effect. Drive or operate machinery only if you are alert.
MOX CLAV DS 457MG TABLET should be swallowed as a whole with water. Take the medicine with a meal.
If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking MOX CLAV DS 457MG TABLET.
The common side effects of MOX CLAV DS 457MG TABLET include vomiting, nausea, and diarrhoea. In case of any discomfort, speak with a doctor.
MOX CLAV DS 457MG TABLET should be taken only if prescribed by the doctor. It should not be taken by people who are allergic to amoxicillin, clavulanic acid, penicillin or any of the other ingredients of this medicine, ever had a severe allergic reaction (skin rash or swelling of the face or throat) to any other antibiotic or liver problems/jaundice (yellowing of the skin) when taking an antibiotic.
Let the doctor know if you are taking gout medicine (allopurinol, probenecid), blood thinners (warfarin), anticancer, or anti-arthritis drugs (methotrexate), and drugs to prevent organ transplant (mycophenolate mofetil).
Seek immediate medical attention if you have overdosed on MOX CLAV DS 457MG TABLET. Taking too much of MOX CLAV DS 457MG TABLET may cause upset stomach (nausea, vomiting or diarrhoea) or convulsions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.9127 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Co Amoxiclav - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Augmentin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Amoxicillin/clavulanate potassium. [Accessed on 25 Jan. 2019]Check here
  5. Amoxicillin and clavulanic acid. 2017. [Accessed on 01 Feb. 2019]Check here
  6. Amoxicillin trihydrate and potassium clavulanate [EMC SmPC]. 2025. [Accessed on 02 Jul. 2025]Check here
  7. Augmentin 625 mg Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 7 July 2025]Check here

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063.
Other Info - MOX0109
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