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compositionComposition:PYRIDOSTIGMINE-60MG
prescription
Prescription Medicine
info
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Myestine 60 Tablet is used to treat myasthenia gravis (muscle weakness). Besides this, it also treats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposure to any nerve poisoning gas. It contains Pyridostigmine, which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, helps in proper muscle functioning and prevents muscle weakness. In some cases, you may experience common side effects, such as stomach pain, nausea, vomiting, diarrhoea, sweating, cough with mucus, rash, muscle cramps, and blurred vision. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PYRIDOSTIGMINE-60MG

Manufacturer/Marketer :

Vhb Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Myestine 60 Tablet

Myestine 60 Tablet is a prescription medicine primarily used to treat myasthenia gravis, a chronic autoimmune condition that causes muscle weakness and fatigue. Living with myasthenia gravis can be challenging, but with the right treatment plan many people are able to manage their symptoms and carry out their daily activities. Myestine 60 Tablet works by improving communication between your nerves and muscles, helping restore muscle strength needed for activities such as chewing, swallowing, and breathing.

For the best results, you must take Myestine 60 Tablet consistently at the exact times prescribed by your doctor, especially if you need it to help with chewing or swallowing. It is generally recommended to take this medicine with food or a small snack to reduce stomach upset. Planning your meals around your dosing schedule can make eating much easier and safer.

While taking Myestine 60 Tablet , you may experience mild side effects such as increased salivation, sweating, mild stomach cramps, or nausea. However, if you notice serious symptoms like extreme muscle weakness, difficulty breathing, or a very slow heart rate, contact your doctor immediately.

Do not take this if you have a physical blockage in your intestines or urinary tract. Before starting Myestine 60 Tablet , let your doctor know if you have asthma, chronic obstructive pulmonary disease (COPD), or any heart rhythm problems, as this medicine can worsen these conditions.

Avoid drinking alcohol while taking this medicine, as it can worsen stomach side effects and increase drowsiness. Talk to your doctor if you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, as your dose may need careful monitoring.

Uses of Myestine 60 Tablet

Myestine 60 Tablet is used to manage the following conditions: 

  • Myasthenia gravis: Myestine 60 Tablet helps improve muscle strength and reduce muscle fatigue in people with this chronic autoimmune disorder.
  • Nerve gas exposure protection: In specific military or government-authorised situations, Myestine 60 Tablet may be used as a preventive measure before potential exposure to certain nerve agents. This is a specialised use and is not a routine civilian indication or self-medication option. 

Key Benefits

Myestine 60 Tablet provides real-world relief by helping you regain control over your muscles. The primary benefits include:

  • Improved Muscle Control: It significantly increases muscle strength, allowing you to perform daily tasks like walking, lifting, and speaking more easily.
  • Easier Eating and Swallowing: By strengthening the muscles in the throat and mouth, Myestine 60 Tablet helps you chew and swallow food safely, reducing the risk of choking.
  • Restored Energy for Daily Activities: It helps prevent the rapid muscle fatigue that typically worsens throughout the day, enabling you to maintain physical activity longer.

Directions for Use

Follow these instructions to take Myestine 60 Tablet safely and effectively: 

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet unless your doctor specifically instructs you to do so. Extended-release tablets must always be swallowed whole, as they are designed to release the medicine slowly over several hours and are often prescribed to provide longer-lasting symptom control, including overnight.
  • Take this medicine at the exact times your doctor prescribes. For example, if you have trouble swallowing during meals, taking your dose 30 to 45 minutes before eating can make a significant difference.
  • Always follow your doctor's exact instructions regarding how and when to take this medicine, and never adjust your timing or dose on your own.

How Myestine 60 Tablet Works

Myestine 60 Tablet contains pyridostigmine, which works by stopping the excessive cholinesterase activity (an enzyme required for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Myestine 60 Tablet helps in proper muscle functioning and prevents muscle weakness.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Myestine 60 Tablet as it may cause increased dizziness.

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Pregnancy

Consult your doctor

Myestine 60 Tablet belongs to the pregnancy category C. Please consult your doctor before taking Myestine 60 Tablet if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Small amounts of Myestine 60 Tablet may pass into breastmilk. Please consult your doctor before taking Myestine 60 Tablet if you are breastfeeding.

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Driving

Unsafe

Myestine 60 Tablet may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking Myestine 60 Tablet if you have liver disease before taking Myestine 60 Tablet .

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Myestine 60 Tablet .

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Children

Unsafe

Not recommended for use in anyone less than 18 years of age

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Heart

Consult your doctor

Consult your doctor before taking Myestine 60 Tablet if you have heart problems or any concerns regarding this.

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Geriatrics

Caution

Careful monitoring and proper dose adjustments are needed while taking Myestine 60 Tablet in elderly patients.

What if I have taken an overdose of Myestine 60 Tablet

In case of an accidental overdose, seek immediate medical attention or call emergency services. Symptoms may include severe muscle weakness, extreme stomach cramps, heavy sweating, blurred vision, difficulty breathing, or a very slow heartbeat. Do not wait for symptoms to become severe before seeking emergency medical care.

Diet & Lifestyle Advise

  • Time your meals carefully: If you have difficulty swallowing, schedule your meals for 30 to 45 minutes after taking Myestine 60 Tablet , when the medicine's effect is strongest.
  • Choose easy-to-chew foods: Opt for softer foods, gravies, and purées during times when muscle weakness is more pronounced to make eating safer and less exhausting.
  • Rest strategically: Plan periods of physical rest throughout the day, particularly before meals or activities that require more physical effort.
  • Keep a daily log: Track your doses, meal times, and muscle strength throughout the day to help your doctor optimise your treatment schedule.
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How Soon It Starts Working

  • The time required for Myestine 60 Tablet to start to work: The time required for Myestine 60 Tablet to start to work is 15 to 30 minutes after administration.
  • The time for which the effects of Myestine 60 Tablet last: The effect of Myestine 60 Tablet lasts for 6 to 8 hours.

What if you forget to take Myestine 60 Tablet

If you miss a dose, take it as soon as you remember. However, if it is within 1 hour of your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Myestine 60 Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F), in a dry place away from direct heat, light, and moisture. •Do not store this medicine in the bathroom, as high humidity can degrade the tablets.

Drug Warnings

  • Differentiate weakness types: Both too little medicine (myasthenic crisis) and too much medicine (cholinergic crisis) can cause worsening muscle weakness and breathing difficulty, and the symptoms can appear similar. Do not change your dose yourself—seek urgent medical attention so your doctor can determine the cause and provide the appropriate treatment.
  • Check the packaging: Always inspect the product packaging and do not take the medicine if it has expired or if the tablets appear damp or crumbly.
  • Carry medical identification: Wear a medical alert bracelet or carry a card stating that you take Myestine 60 Tablet for myasthenia gravis, in case of emergencies.
  • Coordinate medical procedures: Tell any doctor, dentist, or surgeon that you are taking this medicine before undergoing any medical procedures or receiving anaesthetics.
  • Do not stop suddenly: Do not abruptly stop taking Myestine 60 Tablet without consulting your doctor, as this can cause a severe and rapid return of muscle weakness.

Drug-Drug Interactions

verifiedApollotooltip

Some medicines may affect how Myestine 60 Tablet works or increase the risk of side effects. Tell your doctor about all the medicines you are taking, including:

  • Muscle Relaxants: May interact with other medicines that affect muscle function, such as certain muscle relaxants used during surgery, which can have their effects blocked or altered.
  • Antibiotics and Heart Medicines: Combining this medicine with certain antibiotics (like aminoglycosides) or heart medications (like quinidine or beta-blockers) can sometimes worsen muscle weakness.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Myestine 60 Tablet when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MUSCLE STIMULANTS AND CHOLINESTERASE INHIBITORS]

FAQs

Myestine 60 Tablet is used to treat myasthenia gravis (muscle weakness). Besides this, it also treats paralytic ileus (a rare form of constipation), postoperative urinary retention, and prophylaxis to military exposure to any nerve-poisoning gas.
Myestine 60 Tablet works by stopping the excessive cholinesterase activity (an enzyme necessary for the breakdown of a neurotransmitter called acetylcholine) involved in communication between nerve impulses and muscle movements. Thereby, Myestine 60 Tablet helps in proper muscle functioning and prevents muscle weakness.
Myestine 60 Tablet is used as prophylaxis against the lethal effects of soman nerve agent poisoning especially by military. It is intended to be used in conjunction with atropine and pralidoxime therapy and protective garments and gas-mask.
Caution is needed in patients with asthma, breathing difficulty, wheezing and chronic cough as Myestine 60 Tablet may worsen the condition. Please consult your doctor before taking Myestine 60 Tablet if you have asthma or any breathing problems.
Talk to your doctor before taking Myestine 60 Tablet if you have hypertension (high blood pressure) as it may cause insignificant changes such as elevated blood pressure.
Anticholinergic drugs are often used in the treatment of glaucoma. Myestine 60 Tablet is a cholinergic inhibitor, and its use in patients with glaucoma may cause additive effects which could lead to night vision problems. Please consult your doctor before taking Myestine 60 Tablet if you have glaucoma.
Myestine 60 Tablet may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, muscle cramps, blurred vision, rash and increased salivation. If these side effects persist or worsen, please consult your doctor.
Myestine 60 Tablet does not cause high blood pressure. In fact, intake of high dose of Myestine 60 Tablet can cause low blood pressure.
No, Myestine 60 Tablet should not be crushed or chewed. It should be taken as a whole with water.
Myestine 60 Tablet does not cause increase in heartbeats. On the other hand, it can be used in the treatment of increase in heartbeats in postural orthostatic tachycardia syndrome (POTS) where there is an abnormal increase in the heartbeats while standing from a lying position.
No, do not take Myestine 60 Tablet for constipation. It is used only when constipation occurs due to intestinal paralysis and strictly on prescription by the doctor.
Myestine 60 Tablet should not be taken by patients who are allergic to it, who have constipation or difficulty urinating, unless the doctor has advised to use this medicine.
If you have accidentally taken more than the required dose, seek medical help immediately. An overdose of Myestine 60 Tablet may cause nausea, vomiting, stomach pain, diarrhea, salivation, excessive sweating, blurred vision, difficulty in breathing, excessive weakness, and even paralysis.
No, Myestine 60 Tablet is not a steroid. It belongs to the group of medicines called anticholinesterases.
No, there is no proof that Myestine 60 Tablet has abuse potential.
No, Myestine 60 Tablet does not cause weight gain. However, if you gain weight, it may be due to inactivity related to muscle weakness in myasthenia gravis.
Yes, Myestine 60 Tablet is safe if used as advised by the doctor. Do not exceed the recommended dose.
You will typically begin to notice an improvement in your muscle strength within 30 to 45 minutes after taking Myestine 60 Tablet . The peak effect usually lasts for about 3 to 4 hours. Talk to your doctor if you do not feel any improvement.
Yes, you can take it with or without food. However, taking Myestine 60 Tablet with food, milk, or a light snack is highly recommended because it helps prevent common stomach side effects like cramps or nausea. Talk to your doctor or pharmacist for personalised advice.
The best timing depends on when your muscle weakness is most troublesome. Many patients find it most helpful to take a dose 30 to 45 minutes before meals to help with chewing and swallowing. Talk to your doctor to establish the best schedule for you.
No, Myestine 60 Tablet does not cure myasthenia gravis, but it is highly effective at managing and relieving the symptoms. It helps restore muscle strength so you can perform daily activities more easily. Talk to your doctor about long-term management plans.
If your weakness increases shortly after taking your dose, this could indicate that your dose is too high (a cholinergic crisis). You must seek medical attention immediately. Do not adjust your dose without consulting your healthcare provider. Talk to your doctor right away if you experience this.
It is highly advisable to avoid alcohol while taking Myestine 60 Tablet . Alcohol can increase drowsiness, upset your stomach, and interfere with how well you manage your muscle weakness. Talk to your doctor or pharmacist if you have questions about alcohol use.
Myestine 60 Tablet may be used during pregnancy when the expected benefits outweigh the potential risks, but treatment should always be supervised by your doctor. Babies born to mothers with myasthenia gravis or those taking Myestine 60 Tablet may occasionally develop temporary muscle weakness after birth and may require monitoring. If you are pregnant, planning a pregnancy, or breastfeeding, discuss your treatment plan with your doctor.
Some people may experience blurred vision, watering eyes, or mild dizziness while taking Myestine 60 Tablet . If you experience these symptoms, do not drive or operate heavy machinery until you know how the medicine affects you. Talk to your doctor for more safety guidelines.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

50-Ab, Government Industrial Estate, Charkop Naka, Charkop Industrial Estate, Kandivali West, Mumbai, Maharashtra 400067
Other Info - MYE0006

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