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compositionComposition:CYCLOSPORINE-0.1%W/V
prescription
Prescription Medicine
info
Nano 0.5mg Eye Drop 5 ml

Nano 0.5mg Eye Drop 5 ml is used in the treatment of severe keratitis (inflammation of the cornea) in adults. It is also used to treat dry eyes in patients whose condition has not improved with artificial tears. This medicine contains cyclosporine, which helps increase tear production and decrease inflammation (swelling) in the eye. Inform your doctor if you are pregnant or breastfeeding.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CYCLOSPORINE-0.1%W/V

Manufacturer/Marketer :

Sunways (India) Pvt Ltd

Consume Type :

Ophthalmic

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nano 0.5mg Eye Drop 5 ml

Nano 0.5mg Eye Drop 5 ml is used in the treatment of severe keratitis (inflammation of the cornea) in adults. Also, it is used to treat dry eyes in patients whose condition has not improved with artificial tears.

Nano 0.5mg Eye Drop 5 ml contains Cyclosporine, which works by increasing tear production and decreasing inflammation (swelling) in the eye. 

In some cases, Nano 0.5mg Eye Drop 5 ml may cause side effects like irritation, pain, watery eyes, itching, and blurred vision. Consult your doctor if the side effects persist or worsen.

Please tell your doctor if you are allergic to Nano 0.5mg Eye Drop 5 ml or any other medicines. Consult your doctor if you are pregnant or breastfeeding. Drive only if your vision is clear, as Nano 0.5mg Eye Drop 5 ml may cause temporary blurred vision immediately after using.

Uses of Nano 0.5mg Eye Drop 5 ml

Nano 0.5mg Eye Drop 5 ml is used in the treatment of dry eyes and severe keratitis. The detailed uses of Nano 0.5mg Eye Drop 5 ml are as follows:

  • Treatment of Keratitis: Nano 0.5mg Eye Drop 5 ml reduces inflammation in the cornea, helps to relieve discomfort and supports recovery from keratitis symptoms.
  • Dry Eye Relief: Nano 0.5mg Eye Drop 5 ml is used to provide relief from the symptoms of dry eyes, helping to lubricate and moisten the eye surface.
  • Post-Surgical Recovery: After certain eye surgeries, Nano 0.5mg Eye Drop 5 ml can aid in the healing process by maintaining eye moisture and reducing discomfort.
  • Improvement of Tear Film Stability: Nano 0.5mg Eye Drop 5 ml supports the stability of the tear film, which is essential for maintaining clear vision and comfort throughout the day.

Key Benefits

  • Nano 0.5mg Eye Drop 5 ml helps stimulate the eye's natural ability to produce tears, especially in patients with chronic dry eye disease.
  • It provides long-term relief for patients who do not respond adequately to artificial tears.
  • Nano 0.5mg Eye Drop 5 ml decreases inflammation associated with dry eye syndrome and other ocular surface diseases.
  • It helps restore a healthy tear film and improves comfort and vision.
  • Nano 0.5mg Eye Drop 5 ml is used in managing severe cases of keratitis (inflammation of the cornea), particularly when caused by underlying immune-mediated conditions.
  • It helps protect the cornea from damage due to dryness or inflammatory processes.
  • It promotes healing of the eye's surface by maintaining adequate moisture and reducing immune-related damage.
  • Also, supports recovery and maintenance of a stable tear film for better visual function.
Side effects of Nano 0.5mg Eye Drop 5 ml
  • To the affected part, apply warm compresses to get a temporary relief.
  • Rinse your eye carefully with clean water and try to blow any dust particle that could have entered.
  • Take over the counter medication to lubricate your eye or if there is pain due to allergy to soothe the eye.
  • If there is persistent pain in your eye, consult your doctor and follow the medication immediately.
  • Eat a healthy, well-balanced diet full of vitamins, minerals, and omega-3 fatty acids to help maintain eye health.
  • Wear UV-protecting sunglasses when you are outside or in bright light.
  • Avoid touching or rubbing your eyes it may increase irritation.
  • Seek medical care if you are experiencing extreme eye pain or discomfort.
  • Your doctor might recommend eye drops to treat dry eyes, reduce inflammation, or stop irritation.
  • Use a cold, moist towel to relieve inflammation and discomfort.
  • Refrain from rubbing or touching the affected eyelid to avoid worsening the irritation.
  • Avoid allergens like pollen or pet dander that may trigger eyelid erythema.
  • Gently wash the eyelid with mild soap and water to prevent infection.
  • Drink lots of water to keep your skin and eyes moisturized.
  • Inform your doctor if you experience severe symptoms like intense pain, vision changes, or increased sensitivity to light.
  • Avoid rubbing your eyes, which can exacerbate the issue.
  • Lubricate your eyes using artificial tears or eye drops.
  • Wear sunglasses while you are out in the sun to protect your eyes from sun and wind.
  • Avoid irritants like smoke, dust, and strong chemicals.
  • Get enough rest and sleep to help your eyes recover.
  • Stay hydrated by drinking plenty of water.
  • Get plenty of rest to help your eyes recover.
  • Eat a balanced diet low in fat and rich in fruits, vegetables, and whole grains.
  • Limit spicy and seasoned foods that can irritate your eyes.
  • Avoid seafood, which can trigger allergies or infections that worsen red eye symptoms.
  • Talk to the doctor if you notice any visual disturbances.
  • Do not drive or operate machinery unless you have a clear vision.
  • Lubricate the eyes and use a warm compress to gently massage the eyes.
  • Keep your eyes protected from harmful sun rays by wearing sunglasses and a hat.
  • Rest well and eat a balanced diet.
  • Use a humidifier and increase fluid intake.
  • Eat a healthy, low-fat diet rich in whole grains, fruits, and vegetables.
  • Drink plenty of water to stay hydrated.
  • Get adequate sleep and avoid direct sunlight.
  • Follow a low-salt diet to minimize fluid retention.
  • Apply a cold compress to reduce inflammation and soothe affected areas.

Directions for Use

  • Nano 0.5mg Eye Drop 5 ml is typically used 1-2 times a day, or as prescribed by your healthcare provider, based on the severity of the condition.
  • Tilt your head back, gently pull down your lower eyelid to create a small pocket, and instil the prescribed number of drops into the affected eye. Close your eye and gently press the corner of your eye near the nose for 1-2 minutes to prevent the drops from draining out.
  • Avoid touching the dropper to any surface, including your eyes, to prevent contamination.

How Nano 0.5mg Eye Drop 5 ml Works

Nano 0.5mg Eye Drop 5 ml contains Cyclosporine, which works by increasing tear production and decreasing inflammation (swelling) in the eye.
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Alcohol

Caution

The interaction of alcohol with Nano 0.5mg Eye Drop 5 ml is unknown. Please consult a doctor before consuming alcohol with Nano 0.5mg Eye Drop 5 ml.

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Pregnancy

Consult your doctor

Consult your doctor before using Nano 0.5mg Eye Drop 5 ml if you are pregnant. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

If you are breastfeeding, consult your doctor before using Nano 0.5mg Eye Drop 5 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Nano 0.5mg Eye Drop 5 ml may cause temporary blurred vision immediately after applying. Therefore, wait until your vision is clear before driving or operating machinery.

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Liver

Consult your doctor

If you have any concerns regarding the use of Nano 0.5mg Eye Drop 5 ml in patients with liver problems, please consult your doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Nano 0.5mg Eye Drop 5 ml in patients with kidney problems, please consult your doctor.

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Children

Caution

Nano 0.5mg Eye Drop 5 ml should be used in children only if it is advised by a doctor. It is not recommended for use in children less than four years.

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Heart

Safe if prescribed

Nano 0.5mg Eye Drop 5 ml is generally considered safe for heart patients. However, please consult your doctor before using Nano 0.5mg Eye Drop 5 ml.

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Geriatrics

Safe if prescribed

Nano 0.5mg Eye Drop 5 ml is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Nano 0.5mg Eye Drop 5 ml

An overdose of Nano 0.5mg Eye Drop 5 ml is not expected to be dangerous. However, if an overdose is suspected, seek medical help.

Diet & Lifestyle Advise

  • Use a humidifier in your room to increase moisture and avoid dry conditions.
  • Limit the time you spend in front of the television or computer.
  • If dry eyes are caused by environmental factors, wear protective eyewear during outdoor activities when it’s windy and avoid exposure to cigarette smoke.
  • Limit wearing contact lenses and use soft contact lenses if you have dry eyes, as they are moist and allow the eye to breathe better than hard contact lenses.
  • Take omega-3 fatty acid supplements as they may be helpful in treating dry eyes. 

Have a query?

How Soon It Starts Working

The time required for Nano 0.5mg Eye Drop 5 ml to start to work: The onset time of Nano 0.5mg Eye Drop 5 ml has not been clinically established.

The time for which the effects of Nano 0.5mg Eye Drop 5 ml last: The duration of Nano 0.5mg Eye Drop 5 ml’s effect is clinically not established.

What if you forget to take Nano 0.5mg Eye Drop 5 ml

If you miss a dose, use it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule.

Storage

• Store in a cool and dry place away from sunlight.• Keep Nano 0.5mg Eye Drop 5 ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Please tell your doctor if you are allergic to Nano 0.5mg Eye Drop 5 ml or any other medicines.
  • If you are pregnant or breastfeeding, consult a doctor.
  • Avoid using Nano 0.5mg Eye Drop 5 ml while you are wearing contact lenses.
  • Drive only if your vision is clear, as Nano 0.5mg Eye Drop 5 ml may cause temporary blurred vision immediately after use.
  • If you have or had an eye infection, inform your doctor before using Nano 0.5mg Eye Drop 5 ml.
  • You are recommended to maintain a time gap of 15 minutes between using other eye medicines and Nano 0.5mg Eye Drop 5 ml.
  • Discard the bottle after 4 weeks of first opening to prevent infections.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Inform your doctor if you are taking medicines used to treat glaucoma and medicines containing steroids.

Drug-Food Interaction: No interactions found. 

Drug-Disease Interaction: If you have an eye infection or cancer in or around the eye, inform your doctor before using Nano 0.5mg Eye Drop 5 ml.

CiclosporinSimvastatin
Critical
CiclosporinBosentan
Critical

Drug-Drug Interactions

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CiclosporinSimvastatin
Critical
How does the drug interact with Nano 0.5mg Eye Drop 5 ml:
Combining Nano 0.5mg Eye Drop 5 ml and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Nano 0.5mg Eye Drop 5 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBosentan
Critical
How does the drug interact with Nano 0.5mg Eye Drop 5 ml:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Nano 0.5mg Eye Drop 5 ml with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinCidofovir
Critical
How does the drug interact with Nano 0.5mg Eye Drop 5 ml:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Nano 0.5mg Eye Drop 5 ml with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinPitavastatin
Critical
How does the drug interact with Nano 0.5mg Eye Drop 5 ml:
Coadministration of pitavastatin with Nano 0.5mg Eye Drop 5 ml may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Nano 0.5mg Eye Drop 5 ml is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinBaricitinib
Critical
How does the drug interact with Nano 0.5mg Eye Drop 5 ml:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Nano 0.5mg Eye Drop 5 ml with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinZalcitabine
Severe
How does the drug interact with Nano 0.5mg Eye Drop 5 ml:
Co-administration of zalcitabine with Nano 0.5mg Eye Drop 5 ml may significantly decrease the effect of zalcitabine.

How to manage the interaction:
Although there is a possible interaction between Zalcitabine and Nano 0.5mg Eye Drop 5 ml, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.
CiclosporinDocetaxel
Severe
How does the drug interact with Nano 0.5mg Eye Drop 5 ml:
Coadministration of docetaxel with Nano 0.5mg Eye Drop 5 ml may significantly increase the blood levels of docetaxel.

How to manage the interaction:
Although there is a possible interaction between deferasirox and Nano 0.5mg Eye Drop 5 ml, they can be taken together if your doctor has prescribed them. Contact your doctor immediately if experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
CiclosporinFingolimod
Severe
How does the drug interact with Nano 0.5mg Eye Drop 5 ml:
When fingolimod is taken with cyclosporine, it can increase the risk of infection.

How to manage the interaction:
Although taking fingolimod and Nano 0.5mg Eye Drop 5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CiclosporinOrlistat
Severe
How does the drug interact with Nano 0.5mg Eye Drop 5 ml:
Coadministration of Nano 0.5mg Eye Drop 5 ml with Orlistat can reduce the levels and effects of Nano 0.5mg Eye Drop 5 ml.

How to manage the interaction:
Although there is a possible interaction between Orlistat and Nano 0.5mg Eye Drop 5 ml, you can take these medicines together when prescribed by your doctor. Do not stop using any medications without talking to a doctor.
CiclosporinTacrolimus
Severe
How does the drug interact with Nano 0.5mg Eye Drop 5 ml:
Taking tacrolimus with Nano 0.5mg Eye Drop 5 ml may cause serious side effects on the kidneys.

How to manage the interaction:
Although taking tacrolimus and Nano 0.5mg Eye Drop 5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, body aches, and severe pain in your upper stomach spreading to your back. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS]

FAQs

Nano 0.5mg Eye Drop 5 ml is used in the treatment of severe keratitis (inflammation of the cornea) in adults. Also, it is used to treat dry eyes in patients whose condition has not improved with artificial tears.
Nano 0.5mg Eye Drop 5 ml contains Cyclosporine, which works by increasing tear production and decreasing inflammation (swelling) in the eye. Thereby, it provides a soothing effect and relieves irritation and dryness caused by decreased tear flow.
You are recommended to use Nano 0.5mg Eye Drop 5 ml after 15 minutes of using other eye medications only if advised by your doctor. Therefore, inform your doctor if you are using any other medicines before using Nano 0.5mg Eye Drop 5 ml.
Nano 0.5mg Eye Drop 5 ml may cause temporary blurred vision immediately after applying. Therefore, you are recommended to wait until your vision is clear before driving or operating machinery.
You are recommended to avoid wearing contact lenses while using Nano 0.5mg Eye Drop 5 ml as it may cause eye irritation. Therefore, you are advised to remove contact lenses before applying Nano 0.5mg Eye Drop 5 ml and reinsert after 15 minutes of using Nano 0.5mg Eye Drop 5 ml. Also, inform your doctor if you experience pain, stinging or abnormal sensation in the eye after using Nano 0.5mg Eye Drop 5 ml.
You are recommended to discuss with your doctor before using eye drops containing steroids with Nano 0.5mg Eye Drop 5 ml as there is a risk of side effects if both medicines are used simultaneously.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Product Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. National Health Service (NHS). Ciclosporin Info Sheet - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  3. RESTASIS® (cyclosporine ophthalmic emulsion) 0.05% [Internet]. [Accessed on 27 Feb 2025] Check here
  4. Tapia C, Nessel TA, Zito PM. Cyclosporine. [Updated 2023 Aug 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing;[Accessed on 27 Feb 2025] Check here
  5. National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 5280754, Cyclosporine. Retrieved February 27, 2025 Check here
  6. DrugBank. Cyclosporine. DrugBank.[Accessed on 27 Feb 2025] Check here
  7. Novartis Pharmaceuticals UK Limited. Electronic Medicines Compendium (EMC) [Revised in May 2022] [ Accessed on 21st November 2022]Check here

Country of origin

INDIA

Manufacturer/Marketer address

1002-1003, 10th Floor, Windfall, Sahar Plaza, J.B.Nagar, Andheri-Kurla Road, Andheri (East), Mumbai-400059. Maharashtra, India.
Other Info - NAN0159

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