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  3. Nausetil Inj

Nausetil Inj, Pack of 1 Injection
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Nausetil Inj contains prochlorperazine used in the treatment of schizophrenia, acute mania and short-term treatment of anxiety, nausea and vomiting, vertigo (dizziness). It belongs to the class of antipsycotics which works by inhibiting dopamine receptors.
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Composition :

PROCHLORPERAZINE-100MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Nausetil Inj

Nausetil Inj belongs to a class of antipsychotic medications called phenothiazines used to reduce symptoms of major mental disorders such as schizophrenia, and, acute mania. It is also used as a short-term treatment for anxiety. Additionally, it is used to treat symptoms of nausea and vomiting, and vertigo (dizziness) due to inner ear disorders such as Meniere’s syndrome or labyrinthitis. Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave properly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with one’s daily activities.

Nausetil Inj contains Prochlorperazine which decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Nausetil Inj has a calming effect on people suffering from anxiety or mania. Also, Nausetil Inj works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Nausetil Inj prevents nausea and vomiting. 

Nausetil Inj will be administered by a healthcare professional. Do not self-administer. Some people may experience dry mouth, drowsiness, dizziness, blurred vision, and orthostatic hypotension (low blood pressure when standing up from sitting or lying down) as side effects of Nausetil Inj. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Do not take Nausetil Inj if you are known to be allergic to it. Nausetil Inj should be used with caution in elderly patients above 65 years as there is an increased risk of adverse effects. Nausetil Inj is not recommended for children. Please inform your doctor if you are pregnant or breastfeeding before taking Nausetil Inj. Avoid consumption of alcohol with Nausetil Inj as it may increase adverse effects. Avoid exposure to direct sunlight while taking Nausetil Inj as it may cause skin more sensitive to sunlight. If this injection solution comes in contact with your skin, it may cause dermatitis (a type of skin rash). 

Uses of Nausetil Inj

Treatment of Schizophrenia, acute mania and short-term treatment of anxiety, nausea and vomiting, vertigo (dizziness) due to inner ear problems such as Meniere's syndrome and labyrinthitis

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Nausetil Inj will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Nausetil Inj contains Prochlorperazine used to reduce symptoms of major mental disorders such as schizophrenia, acute mania, and short-term treatment of anxiety. It decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Nausetil Inj has a calming effect on people suffering from anxiety or mania. Also, Nausetil Inj works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Nausetil Inj prevents nausea and vomiting. Additionally, it is used to treat symptoms of vertigo (dizziness) due to inner ear disorders such as Meniere’s syndrome or labyrinthitis.

How Nausetil Inj Works

Nausetil Inj contains Prochlorperazine which decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Nausetil Inj has a calming effect on people suffering from anxiety or mania. Also, Nausetil Inj works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Nausetil Inj prevents nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Nausetil Inj out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Nausetil Inj
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Uncontrolled and involuntary movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

What if I have taken an overdose of Nausetil Inj

Nausetil Inj is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. An overdose may result in drowsiness and certain side effects, including temporary uncontrollable movements of the lips, eyes, head, and neck. Your doctor will take immediate necessary action if an overdose is suspected.

Drug Warnings

Do not take Nausetil Inj if you are known to be allergic to Nausetil Inj. Nausetil Inj should be used with caution in elderly patients above 65 years as there is an increased risk of adverse effects. Nausetil Inj is not recommended for children. Please inform your doctor if you are pregnant or breastfeeding before taking Nausetil Inj. Avoid consumption of alcohol with Nausetil Inj as it may increase adverse effects. Avoid exposure to direct sunlight while taking Nausetil Inj as it may cause skin more sensitive to sunlight. If the injection solution comes in contact with your skin, it may cause dermatitis (a type of skin rash). If you have fits, depression, diabetes, pheochromocytoma (tumour on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Nausetil Inj. 

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
ProchlorperazineMesoridazine
Critical

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
How does the drug interact with Nausetil Inj:
Coadministration of metoclopramide and Nausetil Inj can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Nausetil Inj together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
ProchlorperazineMesoridazine
Critical
How does the drug interact with Nausetil Inj:
Coadministration of mesoridazine and Nausetil Inj can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking mesoridazine with Nausetil Inj is not recommended, but it can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
ProchlorperazineCitalopram
Severe
How does the drug interact with Nausetil Inj:
Taking Nausetil Inj with Citalopram can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Nausetil Inj with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without first consulting your doctor.
ProchlorperazineKetamine
Severe
How does the drug interact with Nausetil Inj:
Coadministration of Nausetil Inj with ketamine can increase the risk or severity of side effects.

How to manage the interaction:
Taking Nausetil Inj with Ketamine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience dizziness, sleepiness, confusion, inability to concentrate, excessive sedation, and breathing problems. Do not stop using any medications without a doctor's advice.
ProchlorperazineEscitalopram
Severe
How does the drug interact with Nausetil Inj:
Taking Nausetil Inj and Escitalopram together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Nausetil Inj with Escitalopram together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineFingolimod
Severe
How does the drug interact with Nausetil Inj:
Taking Nausetil Inj and Fingolimod together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Nausetil Inj with Fingolimod together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without first talking to your doctor.
ProchlorperazineTramadol
Severe
How does the drug interact with Nausetil Inj:
Co-administration of tramadol with Nausetil Inj can increase the risk of seizures(fits).

How to manage the interaction:
Taking Nausetil Inj and tramadol together can possibly result in an interaction; it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ProchlorperazineNilotinib
Severe
How does the drug interact with Nausetil Inj:
Taking Nausetil Inj and Nilotinib together can increase the risk of an abnormal heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Nausetil Inj and Nilotinib, but it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without talking to your doctor.
ProchlorperazineHaloperidol
Severe
How does the drug interact with Nausetil Inj:
Coadministration of Nausetil Inj and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Coadministration of Nausetil Inj and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting your doctor.
ProchlorperazineQuinidine
Severe
How does the drug interact with Nausetil Inj:
Taking Nausetil Inj and Quinidine together can increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Nausetil Inj with Quinidine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 
  • Include more cool beverages in your food, like flavoured gelatin and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
  • Drink any other liquid at least 30 minutes after eating food. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.
  • Avoid consumption of alcohol as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS
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Alcohol

Unsafe

Avoid consumption of alcohol with Nausetil Inj as it may increase the risk of adverse effects and cause severe breathing difficulties.

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Pregnancy

Caution

There is no information on the use of Nausetil Inj during pregnancy. Please inform your doctor if you are pregnant before taking Nausetil Inj. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Nausetil Inj is not recommended to be used in breastfeeding unless absolutely necessary. Before taking this medication, discuss the risks and benefits with your doctor. Depending on your clinical condition, your doctor may prescribe a safer alternative.

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Driving

Caution

Nausetil Inj may cause dizziness, drowsiness or blurred vision in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Nausetil Inj.

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Liver

Caution

Take Nausetil Inj with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Nausetil Inj with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

Nausetil Inj is not recommended for children as safety and efficacy data are not available.

Have a query?

FAQs

Nausetil Inj belongs to a class of antipsychotic medications called phenothiazines used to reduce symptoms of major mental disorders such as schizophrenia, and, acute mania. It is also used as a short-term treatment for anxiety.

Nausetil Inj contains Prochlorperazine, an antipsychotic drug that decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Also, Nausetil Inj works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Nausetil Inj prevents nausea and vomiting.

Yes, Nausetil Inj may be used to treat vertigo (spinning sensation) caused due to ear problems such as Meniere’s syndrome (a disorder of the inner ear).

Nausetil Inj may cause photosensitivity (extreme sensitivity to sunlight) if used in high doses. Therefore, avoiding exposure to direct sunlight while taking Nausetil Inj is recommended.

Nausetil Inj should be used with caution in diabetes patients as it may increase blood sugar levels. Therefore, if you are diabetic, regular monitoring of blood sugar levels is recommended while on treatment with Nausetil Inj.

Nausetil Inj may cause low blood pressure in some patients while standing up suddenly from a sitting or lying down position and cause symptoms such as dizziness, sweating, nausea or fainting. Therefore, to avoid such side effects, you are recommended to get up slowly after lying down or sitting.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - NAU0020

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:23 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/6623/pil
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/010571s096lbl.pdf
  3. https://www.drugs.com/drug-interactions/prochlorperazine.html

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