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compositionComposition:NEPAFENAC-0.3%W/V
prescription
Prescription Medicine
info
Nepaflam OD Eye Drops 3 ml
Nepaflam OD Eye Drops 3 ml
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NEPAFENAC-0.3%W/V

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

Ophthalmic

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nepaflam OD Eye Drops 3 ml

Nepaflam OD Eye Drops 3 ml is a specialised eye drop prescribed to manage pain and reduce inflammation after cataract surgery. This medication belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs) designed specifically for use in the eyes. It helps ensure a more comfortable recovery by targeting inflammation at the surgical site.

To get the best results, you must use this medication consistently and exactly at the intervals prescribed by your doctor, typically starting shortly before your surgery and continuing for a few weeks afterward. You will apply this medicine by instilling the drops directly into the affected eye. Along with using these drops, wearing protective sunglasses outdoors and avoiding rubbing your eyes will greatly support your healing process.

While using Nepaflam OD Eye Drops 3 ml, you might experience mild, temporary symptoms such as a dry or sticky feeling in the eye or a slight burning sensation immediately after application. However, if you experience severe eye pain, sudden changes in your vision, or extreme redness, you must consult your doctor immediately.

Before starting this treatment, tell your doctor if you have a history of bleeding problems, diabetes, or dry eye syndrome or if you have had multiple eye surgeries. Do not use this medicine if you have a known allergy to NSAIDs, aspirin, or any of the ingredients in these drops.

You should also discuss with your doctor if you are taking blood thinners or using steroid eye drops, as these can interact with Nepaflam OD Eye Drops 3 ml and delay your healing. Avoid smoking and dusty environments during your recovery, and consult your healthcare provider if you are pregnant, breastfeeding, or managing care for an elderly patient.

Uses of Nepaflam OD Eye Drops 3 ml

Nepaflam OD Eye Drops 3 ml used in the treatment of eye pain and inflammation after cataract surgery. The detailed uses of Nepaflam OD Eye Drops 3 ml are as follows:

  • Post-operative inflammation: Nepaflam OD Eye Drops 3 ml is used to reduce inflammation and pain after cataract surgery, promoting faster healing and improving surgical outcomes.
  • Pain relief: Nepaflam OD Eye Drops 3 ml helps to relieve pain and discomfort in the eyes after surgery, allowing patients to recover more comfortably.

Key Benefits

Nepaflam OD Eye Drops 3 ml helps manage inflammation and discomfort in the eye, supporting a smoother recovery after eye surgery or other eye-related conditions. By acting directly at the site of inflammation, it helps improve comfort and promotes healing.

  • Helps Reduce Eye Inflammation and Discomfort: By targeting inflammation within the eye, Nepaflam OD Eye Drops 3 ml helps relieve pain, redness, irritation, and post-procedural discomfort, allowing you to carry out daily activities more comfortably.
  • Supports Recovery After Eye Procedures: Controlling inflammation can help promote healing and improve overall comfort during the recovery period following eye surgery or other ophthalmic procedures.
  • Provides Targeted Local Treatment: Because the medicine is applied directly to the eye, it delivers treatment precisely where it is needed. This localised action helps minimise systemic exposure while providing effective relief of eye symptoms.
Side effects of Nepaflam OD Eye Drops 3 ml
  • Eating foods high in vitamins C (like oranges, peppers, and tomatoes) and E (like peanuts, spinach, and broccoli) may help protect your eyes from cataracts or slow them down.
  • Quit smoking and cut back on alcohol.
  • Wear sunglasses when you are outside to protect your eyes from the sun.
  • Keep your blood sugar under control, because high blood sugar can cause changes in the eye lens that lead to cataracts.
  • Have regular eye checkups to catch any problems early.
  • Gently flush the eye with clean, lukewarm water to remove any debris.
  • Use lubricating eye drops (artificial tears) to soothe irritation and re-lubricate the eye.
  • Apply a warm compress to the closed eyelid to loosen any foreign particles.
  • Practice good eyelid hygiene by gently massaging with a clean washcloth.
  • Avoid rubbing your eye to prevent worsening irritation and potential corneal scratches.
  • Do not attempt to remove a foreign object with sharp instruments to avoid further damage.
  • Seek medical attention immediately if you experience severe or persistent symptoms, significant pain, redness, or vision changes.
  • Take healthy and balanced diet.
  • Exercise regularly and maintain the healthy lifestyle.
  • Reduce the intake of caffeine.
  • Use a pillow and elevate your head while sleeping.
  • Place cool compresses over your eyes, it may ease discomfort and inflammation.
  • Avoid taking high-sugar foods and beverages, they can contribute to inflammation throughout the body, including the eyes.
  • Avoid the intake of alcohol, dairy products and processed and fried foods.
  • Take diet containing vitamin A-rich foods like carrots, sweet potatoes, spinach, kale, and apricots in your diet.
  • Avoid touching your eyes with hands frequently without washing.
  • Maintain eye hygiene by washing any discharge from around your eyes several times a day using a clean, wet washcloth or fresh cotton ball.
  • Eat a balanced diet rich in omega-3 fatty acids, vitamins A and C, and antioxidants to support eye health.
  • Include foods high in antioxidants, such as leafy greens, berries, and nuts.
  • Wear protective eyewear during activities that may pose a risk to your eyes.
  • Refrain from touching or rubbing your eyes to minimize potential irritation and prevent exacerbating the condition.
  • Maintain good hygiene and clean your contact lenses properly (if applicable).
  • Get regular eye exams to monitor the condition and adjust treatment as needed.
  • Manage underlying conditions, such as glaucoma or diabetes, to reduce the risk of corneal edema.
  • Eat vitamin A-rich foods like fish liver, chicken, eggs, carrots, lemons, and mangoes in your diet.
  • Eat green leafy vegetables, meat, and dairy products, and increase the consumption of omega-3 fatty acids found in salmon and walnuts.
  • Examine your eyes regularly to detect any underlying issues.
  • Stay hydrated by drinking plenty of water.
  • Eat a well-balanced diet that includes more vegetables, fruits, fish, whole grains, nuts, legumes, and olive oil, and less dairy, meat, and saturated fats.
  • Follow a healthy lifestyle by drinking plenty of water and taking sufficient rest.
  • Eat balanced diet rich in whole grains, fruits, and vegetables, while minimizing fatty, spicy, and seasoned foods.
  • Additionally, avoid seafood to reduce the risk of allergic reactions or infections that may exacerbate symptoms.

Directions for Use

  • Nepaflam OD Eye Drops 3 ml is for ophthalmic (for eye) use only.
  • It is recommended to instill one drop of Nepaflam OD Eye Drops 3 ml 3 times daily or as directed by your doctor.
  • Check the label for directions before using this medication.
  • Lie down and tilt your head backward. Gently pull your lower eyelid with your index finger to form a pocket. Instil the prescribed number of drops into the pocket. Close your eyes for 1-2 minutes.
  • Replace the cap tightly after each use.
  • Avoid touching the container tip to the eye or eyelids to prevent contamination.

How Nepaflam OD Eye Drops 3 ml Works

Nepaflam OD Eye Drops 3 ml contains nepafenac. It works by blocking certain natural enzymes in the body known as cyclooxygenase (COX) enzymes. These enzymes are responsible for producing chemicals called prostaglandins, which the body releases in response to injury or surgery. Prostaglandins cause the redness, swelling, heat, and pain associated with inflammation. When you apply Nepaflam OD Eye Drops 3 ml to your eye, the liquid penetrates the eye tissue and converts into its active form. Once active, it stops the production of these inflammatory chemicals. By lowering prostaglandin levels directly within the eye, the medicine effectively calms swelling, reduces redness, and relieves pain.
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Alcohol

Unsafe

One should avoid consuming alcohol as it is unknown this drug interacts with alcohol or not.

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Pregnancy

Caution

During pregnancy, Nepaflam OD Eye Drops 3 ml can only be used when prescribed by the doctor during the first 6 months. This medicine can not be used during the last 3 months of pregnancy as it may harm a fetus.

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Breast Feeding

Consult your doctor

Nepaflam OD Eye Drops 3 ml can only be used in breastfeeding women if suggested by the doctor, as it is unknown whether this drug passes into breast milk.

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Driving

Unsafe

Nepaflam OD Eye Drops 3 ml may cause blurred vision, so one should avoid driving after using this medicine.

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Liver

Safe if prescribed

Nepaflam OD Eye Drops 3 ml is safe to use if prescribed by the doctor.

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Kidney

Safe if prescribed

Nepaflam OD Eye Drops 3 ml is safe to use if prescribed by the doctor.

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Children

Unsafe

Nepaflam OD Eye Drops 3 ml is not approved to use in children younger than 10 years old.

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Heart

Consult your doctor

Please consult your doctor before using Nepaflam OD Eye Drops 3 ml if you have pre-existing heart problems. Your doctor will prescribe Nepaflam OD Eye Drops 3 ml if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Nepaflam OD Eye Drops 3 ml to geriatric patients. Your doctor will prescribe Nepaflam OD Eye Drops 3 ml if the benefits outweigh the risks.

What if I have taken an overdose of Nepaflam OD Eye Drops 3 ml

If you accidentally put too many drops in your eye, rinse your eye thoroughly with clean, warm water. If the liquid is accidentally swallowed, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Wear UV-protective sunglasses when outdoors to shield your healing eye from bright sunlight and wind.
  • Do not rub, press, or touch your eye, as this can disrupt the healing process and cause injury to the delicate surgical site.
  • Avoid dusty, smoky, or windy environments to prevent foreign particles from irritating your eye.
  • Avoid swimming, using hot tubs, or getting soapy water directly in your eye until your doctor confirms your eye has fully healed.
  • Focus on a balanced diet rich in vitamins A, C, and E, which support tissue repair and overall eye health.

Have a query?

How Soon It Starts Working

  • The time required for Nepaflam OD Eye Drops 3 ml to start to work: Nepaflam OD Eye Drops 3 ml ideally shows its action within 15 minutes after administration.
  • The time for which the effects of Nepaflam OD Eye Drops 3 ml last: The effect of Nepaflam OD Eye Drops 3 ml lasts for 8 hours.

What if you forget to take Nepaflam OD Eye Drops 3 ml

If you miss a dose, apply the missed drop as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed drop and resume your regular routine. Do not apply a double dose to make up for a missed one.

Storage

• Store Nepaflam OD Eye Drops 3 ml at room temperature, safely between 15°C and 30°C. • Do not freeze the bottle, and keep it away from direct sunlight and excessive heat.

Drug Warnings

  • Always inspect the liquid before use; do not use the drops if the solution looks cloudy, discoloured, or contains floating particles.
  • Do not wear contact lenses while recovering from cataract surgery or while using this medication unless specifically instructed otherwise by your doctor.
  • If you use other eye medications, wait at least 5 to 10 minutes after applying Nepaflam OD Eye Drops 3 ml before putting in other drops to prevent them from washing each other out.
  • Avoid driving or operating machinery immediately after applying the drops, as your vision may be temporarily blurry.
  • Contact your doctor immediately if you notice any signs of an eye infection, such as pus, heavy crusting, or increased sensitivity to light.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

  • Steroid eye drops: Using these drops at the same time as Nepaflam OD Eye Drops 3 ml can significantly slow down the healing process of your eye and increase the risk of serious corneal complications.
  • Blood thinners or oral NSAIDs: Combining these medications may increase the risk of internal bleeding in the eye tissues during or after surgery.

 

Drug-Disease Interactions

  • Diabetes: Patients with diabetes have a higher risk of developing corneal side effects, such as thinning or breakdown of the clear outer layer of the eye, when using this medication.
  • Dry eye syndrome: If you suffer from severe dry eyes, this medicine must be used with caution, as it can increase the risk of surface damage to the eye.
  • Bleeding disorders: If you have a history of bleeding tendencies, this medicine may increase the risk of bleeding in the eye tissues post-surgery.
NepafenacAbciximab
Severe

Drug-Drug Interactions

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NepafenacAbciximab
Severe
How does the drug interact with Nepaflam OD Eye Drops 3 ml:
Using Nepaflam OD Eye Drops 3 ml and Abciximab can interfere with clotting and cause bleeding, especially when used regularly or for prolonged periods.

How to manage the interaction:
Although taking Nepaflam OD Eye Drops 3 ml and Abciximab together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood, severe headache, and weakness call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[OPHTHALMOLOGIC AGENTS]

FAQs

Nepaflam OD Eye Drops 3 ml is used to relieve eye irritation, pain, and redness after a cataract eye surgery. This medicine is also indicated to reduce the risk of macular oedema and swelling in the back of the eye after cataract surgery in patients dealing with diabetes.

Nepaflam OD Eye Drops 3 ml works by blocking the synthesis of prostaglandins responsible for causing pain, redness, and inflammation in the eyes. Thereby, it provides relief from pain and inflammation.

You should not use this medicine for longer than 14 days after having cataract surgery unless suggested by the doctor.

Follow your doctor's recommendations. The frequency of use will be determined by your unique condition and prescribed dosage. Overuse can cause adverse effects.

No. Nepaflam OD Eye Drops 3 ml is primarily used for inflammation and pain, not for dry eye conditions. For dry eyes, you might consider artificial tears or other specific treatments.

The most common side effects of using Nepaflam OD Eye Drops 3 ml include blurred vision, reduced vision, and changes in vision. Most of these side effects do not require medical attention and may resolve over time. However, consult the doctor if the side effects persist or worsen.

Consult your doctor before using Nepaflam OD Eye Drops 3 ml if you're pregnant or breastfeeding. They can assess the potential risks and benefits for you and your baby.

Rinse your mouth or nose with plenty of water and contact your doctor if you experience any adverse symptoms.

Yes, wearing sunglasses can help protect your eyes from light sensitivity.

Store in a cool and dry place away from sunlight. Keep Nepaflam OD Eye Drops 3 ml out of the sight and reach of children.

If you have a history of allergies, inform your doctor before using Nepaflam OD Eye Drops 3 ml. They can assess your risk of allergic reactions.

Use the missed dose as soon as you remember. If it's almost time for your next scheduled dose, skip the missed dose and continue your regular dosing schedule.

The onset of action for Nepaflam OD Eye Drops 3 ml can vary depending on individual factors. However, many people notice a reduction in pain and inflammation within a few hours of using the medication.

You should avoid wearing contact lenses entirely during your recovery from cataract surgery. If your doctor explicitly permits contact lens use, you must remove them before applying Nepaflam OD Eye Drops 3 ml and wait at least 15 minutes before reinserting them. Talk to your doctor for specific guidance.

The duration of treatment depends on your individual healing progress. Your doctor will provide a specific schedule, which usually lasts for a few weeks post-surgery. Talk to your doctor before stopping the drops early.

A mild, brief stinging or burning sensation is common and usually passes within a minute. However, if the stinging is severe, worsens, or is accompanied by persistent pain and redness, stop using the drops and talk to your doctor immediately.

Yes, but you must space the applications out. Wait at least 5 to 10 minutes between using Nepaflam OD Eye Drops 3 ml and your glaucoma drops to prevent one drop from washing out the other. Talk to your doctor or pharmacist to plan your schedule.

Your vision may be temporarily blurred for a few minutes after you apply the drops. Do not drive, ride a bicycle, or operate machinery until your vision is completely clear. Talk to your doctor if blurred vision persists.

If the dropper tip touches your eye, eyelid, or fingers, it can become contaminated with bacteria, which may cause an eye infection. If this happens, wipe the tip with a clean tissue or consult your pharmacist about whether you need a replacement bottle. Talk to your doctor if you develop signs of an infection.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.6549 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. U.S. Food and Drug Administration (FDA). 203491S001Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Nepafenac. [Updated 2018 Dec 3] Check here
  4. Alcon Laboratories, Inc. 2005, U.S. Food & Drug Administration. [Revised in June 2011]. [Accessed on 8th November 2022] docs/label/2011/021862s008lbl.pdf Check here
  5. Novartis Pharmaceuticals UK Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2021]. [Accessed on 8th November 2022] Check here
  6. Central Drugs Standard Control Organisation (CDSCO): Nepafenac. [Accessed on 26 Feb. 2026] Check here
  7. Nepafenac [Prescribing Information]. 2020. [Accessed on 26 Feb. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - NEP0067

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