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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nexchio IT Capsule is used to treat acidity, gastro-oesophageal reflux disease (GERD), stomach ulcers (peptic ulcers, gastric ulcers due to H pylori), heartburn symptoms and Zollinger Ellison syndrome. It contains Esomeprazole and Itopride, which block the production of stomach acid. Also, it increases the gastric emptying time, thereby improving the movement/motility of the food pipe, stomach, and intestine. In some cases, you may experience certain common side effects, such as headache, flatulence, stomach pain, constipation, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Sachio Pharma Bangalore Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nexchio IT Capsule

Nexchio IT Capsule is used to treat acidity, gastro-oesophageal reflux disease (when stomach acid frequently flows back into the oesophagus), stomach ulcers (peptic ulcers, gastric ulcers due to H pylori), heartburn symptoms, and Zollinger-Ellison syndrome. Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.

Nexchio IT Capsule is a combination of esomeprazole and Itopride. Esomeprazole works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of stomach acid. Itopride works by increasing the gastric emptying time.

In some cases, you may experience certain common side effects, such as headache, flatulence, stomach pain, constipation, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Take Nexchio IT Capsule 30-60 minutes before food/meal. Swallow Nexchio IT Capsule as a whole with a glass of water; do not chew or crush it. You are advised to take Nexchio IT Capsule for as long as your doctor has prescribed it for you, depending on your medical condition.

Consult your doctor if you are pregnant or breastfeeding. Nexchio IT Capsule may cause dizziness, so drive only if you are alert. Nexchio IT Capsule should not be given to children as safety has not been established. Keep your doctor informed about all the medicines and your health condition to rule out any side effects.

Uses of Nexchio IT Capsule

Nexchio IT Capsule is used to treat acid-related conditions. The detailed uses of Nexchio IT Capsule are as follows:

  • Gastroesophageal reflux disease (GERD): Nexchio IT Capsule reduces acid reflux and heartburn by lowering stomach acid and improving stomach motility.
  • Dyspepsia: Nexchio IT Capsule reduces bloating, nausea, and a feeling of fullness by helping the stomach empty properly.
  • Peptic ulcers: Nexchio IT Capsule aids in healing ulcers in the stomach and upper intestine by managing acid levels.
  • Chronic gastritis: Nexchio IT Capsule treats stomach lining inflammation and provides symptom relief.
  • Zollinger-Ellison syndrome: Nexchio IT Capsule controls excess acid production in this rare condition and manages gastric and duodenal ulcers.

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Directions for Use

  • Take Nexchio IT Capsule 30-60 minutes before food or a meal.
  • It is advised to take Nexchio IT Capsule once daily, as prescribed by your doctor, to achieve optimal results.
  • Swallow Nexchio IT Capsule as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Nexchio IT Capsule is a combination medicine used to treat acidity, gastro-oesophageal reflux disease (GERD), stomach ulcer and heartburn.
  • Nexchio IT Capsule is a combination of two drugs: Esomeprazole and Itopride.
  • Esomeprazole belongs to a group of medicines called proton pump inhibitors, which work by blocking the action of an enzyme called the gastric proton pump, responsible for the production of stomach acid.
  • Itopride belongs to a group of medicines called prokinetic agents which works by accelerating the gastric emptying time, thereby increasing the movement of the food pipe, intestine and stomach.
  • Besides this, Itopride also has anti-emetic action, which prevents the symptoms of nausea and vomiting.
  • Together, Nexchio IT Capsule helps in preventing acid reflux, thereby providing relief from hyperacidity, ulcers and heartburn.

How Nexchio IT Capsule Works

Nexchio IT Capsule is a combination of two drugs: Esomeprazole and Itopride. Esomeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of stomach acid. Itopride is a gastroprokinetic agent that works by increasing the gastric emptying time, thereby improving the movement/motility of the food pipe, stomach, and intestine. Together, Nexchio IT Capsule helps in preventing acid reflux, thereby providing relief from symptoms of excessive stomach acid production, which causes an ulcer.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Nexchio IT Capsule

Do not take more than the prescribed dose of Nexchio IT Capsule as it may cause an overdose. The symptoms of overdose include severe gastrointestinal disturbances, confusion, and drowsiness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Nexchio IT Capsule if you are allergic to any of its contents; if you are taking nelfinavir (anti-HIV); if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment.
  • Inform your doctor before taking Nexchio IT Capsule if you have severe liver or kidney problems, or if you are due to have a Chromogranin A test.
  • Consult your doctor if you experience unexplained weight loss, stomach pain, indigestion, vomiting food or blood, or if you pass black stools.
  • On long-term treatment, Nexchio IT Capsule may cause osteoporosis, hypomagnesemia (low levels of magnesium), and may reduce the absorption of vitamin B12.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Nexchio IT Capsule may cause dizziness, so drive only if you are alert.
  • Nexchio IT Capsule should not be given to children as safety has not been established.
  • Avoid consuming alcohol along with Nexchio IT Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. 

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight through regular exercise.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as they might increase the pressure on the abdomen, leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat, spicy foods, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda. 
  • Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Nexchio IT Capsule . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Consult your doctor

Consult your doctor before taking Nexchio IT Capsule if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Nexchio IT Capsule if you are breastfeeding; your doctor will decide whether Nexchio IT Capsule can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Nexchio IT Capsule may cause dizziness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Consult your doctor before taking Nexchio IT Capsule if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Consult your doctor before taking Nexchio IT Capsule if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Nexchio IT Capsule should not be given to children as the safety and effectiveness were not established.

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Heart

Caution

Nexchio IT Capsule should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems.

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Geriatrics

Caution

Nexchio IT Capsule should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Nexchio IT Capsule .

FAQs

Nexchio IT Capsule is used to treat acidity, gastro-oesophageal reflux disease (GERD), stomach ulcers (peptic ulcers, gastric ulcers due to H pylori), heartburn symptoms and Zollinger Ellison syndrome.

Nexchio IT Capsule contains Esomeprazole and Itopride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Itopride works by accelerating gastric emptying and improves gastric sensitivity and tension. It also has anti-emetic action. Together, Nexchio IT Capsule helps in preventing acid reflux, thereby providing relief from acidity.

Diarrhoea might be a side-effect of Nexchio IT Capsule . Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Nexchio IT Capsule may increase the risk of bone fracture in the hip, spine or wrist. This mainly occurs in people taking higher doses of Nexchio IT Capsule for longer durations. Inform your doctor before taking Nexchio IT Capsule if you have osteoporosis or if you are taking corticosteroids.

Both medications are used to treat heartburn, acidity, stomach ulcers, and Zollinger-Ellison syndrome. Sompraz 40 contains only Esomeprazole as its active ingredient, while Nexchio IT Capsule contains Esomeprazole and Itopride as active components.

Both medications effectively treat heartburn, acidity, stomach ulcers, and Zollinger-Ellison syndrome. Pan D contains Pantoprazole and Domperidone, while Nexchio IT Capsule includes Esomeprazole and Itopride as active components.

Nexchio IT Capsule may cause side effects such as headache, flatulence, stomach pain, constipation, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, if you experience these side effects persistently, consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

42/1, 303, Sree Durga 3Rd Cross Mallesh Palaya Ka 560075 In
Other Info - NEX0350

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