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compositionComposition:CILNIDIPINE-10MG+OLMESARTAN MEDOXOMIL-20MG
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Prescription Medicine
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Nexovas O Tablet is used to treat high blood pressure (hypertension). It effectively lowers elevated blood pressure and supports better heart function. It is especially helpful for individuals with moderate to severe hypertension or those at high cardiovascular risk since it keeps blood pressure levels within normal ranges, lowering the risk of major problems like heart attack, stroke, heart failure, and kidney damage.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CILNIDIPINE-10MG+OLMESARTAN MEDOXOMIL-20MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nexovas O Tablet

Nexovas O Tablet is a prescription tablet used to treat high blood pressure (hypertension) when a single medicine is not enough. It combines two active ingredients to lower blood pressure, which helps prevent future heart attacks, strokes, and kidney problems.

To get the most benefit, you should take this medicine consistently at the same time every day, either with or without food. Along with taking Nexovas O Tablet , adopting a heart-healthy diet low in salt and staying physically active can significantly improve your blood pressure readings.

While taking Nexovas O Tablet , some people may experience mild side effects like dizziness, ankle swelling, or a mild headache. If you experience severe symptoms such as sudden swelling of the face, lips, or tongue, or if you feel extremely lightheaded, seek medical help immediately.

Before starting this medication, talk to your doctor or pharmacist if you have liver damage, severe kidney disease, or heart problems. Do not take this if you are pregnant, planning to become pregnant, or have a known allergy to any of its ingredients.

This medicine can interact with alcohol, which may cause your blood pressure to drop too low and make you feel dizzy. It also interacts with potassium supplements and other blood pressure drugs, so pregnant or breastfeeding women, as well as elderly individuals, should consult their healthcare provider before using Nexovas O Tablet .

Uses of Nexovas O Tablet

Your doctor may prescribe this medicine to treat several conditions, including:

  • High blood pressure (Hypertension): Nexovas O Tablet helps relax and widen the blood vessels, which lowers blood pressure and makes it easier for your heart to pump blood throughout your body.
  • Prevention of heart attacks and strokes: By keeping your blood pressure within a healthy range over the long term, this medicine reduces the strain on your arteries and lowers your risk of serious cardiovascular events.
     

Key Benefits

Taking Nexovas O Tablet provides long-term support for managing high blood pressure by helping maintain healthy blood pressure levels and protecting your cardiovascular system. Key benefits include:

  • Maintains Consistent Blood Pressure Control: By helping keep blood pressure within a healthier range throughout the day, Nexovas O Tablet reduces the strain on your heart and blood vessels.
  • Supports Protection of Vital Organs: Regular blood pressure management helps protect important organs, including the heart, kidneys, and blood vessels, from the harmful effects of uncontrolled hypertension.
  • Simplifies Daily Treatment: As a combination medicine, Nexovas O Tablet helps reduce the need for multiple separate pills, making it easier to follow your prescribed treatment routine consistently.
     
Side effects of Nexovas O Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Take Nexovas O Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

How Nexovas O Tablet Works

Nexovas O Tablet contains two active ingredients that work in different ways to lower your blood pressure. The first component, olmesartan medoxomil, is an angiotensin receptor blocker (ARB). It works by blocking a natural substance in the body that causes blood vessels to tighten and narrow, allowing the blood vessels to relax. The second component, cilnidipine, is a calcium channel blocker. It prevents calcium from entering the muscle cells of your blood vessels, which stops them from contracting and helps them widen. Together, these two actions reduce the pressure inside your blood vessels, making it much easier for your heart to circulate blood.
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Alcohol

Unsafe

Nexovas O Tablet can lower your blood pressure causing dizziness and drowsiness. It can also cause orthostatic hypotension (sudden fall in blood pressure while standing). So try to avoid intake of Nexovas O Tablet with alcoholic beverages.

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Pregnancy

Unsafe

Nexovas O Tablet is pregnancy risk category D medicine which may cause harm to the fetus or unborn baby. So, when pregnancy is detected, discontinue Nexovas O Tablet as soon as possible and consult the doctor.

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Breast Feeding

Consult your doctor

Nexovas O Tablet passes into the breast milk. But its effect on the baby is not clear. However, contacting the doctor before intake of Nexovas O Tablet is advisable.

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Driving

Unsafe

Nexovas O Tablet may cause side effects that could affect your ability to drive. Taking Nexovas O Tablet may lower your blood pressure

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Liver

Caution

Nexovas O Tablet to be taken with caution, especially if you have a liver disease history. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Consult your doctor

Nexovas O Tablet is not recommended in patients with chronic kidney disease (severe renal impairment). Please inform your doctor if you had a history of kidney disease. Your doctor may adjust the dose if required based on your condition.

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Children

Unsafe

Nexovas O Tablet is not recommended in children. The safety and efficacy of Nexovas O Tablet in children have not yet been established

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Heart

Caution

Nexovas O Tablet is often prescribed to patients with heart problems to treat hypertension. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.

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Geriatrics

Caution

Nexovas O Tablet should be taken with caution in geriatric patients. Please inform your doctor before using Nexovas O Tablet .

What if I have taken an overdose of Nexovas O Tablet

If you accidentally take too much of this medicine, you may experience severe dizziness, a very slow or fast heartbeat, or fainting. Seek immediate emergency medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Reduce salt intake: Limit your daily sodium intake by avoiding processed foods and not adding extra salt to your meals, as sodium raises blood pressure.
  • Eat potassium-rich foods cautiously: Because certain blood pressure medicines can raise potassium levels in your blood, talk to your doctor before eating large amounts of high-potassium foods like bananas or using salt substitutes containing potassium.
  • Stay hydrated: Drink plenty of water throughout the day, as dehydration can worsen dizziness and lightheadedness when taking blood pressure medications.
  • Engage in regular aerobic exercise: Aim for at least 30 minutes of moderate activity, like brisk walking, most days of the week to naturally strengthen your heart and lower blood pressure.
  • Limit alcohol consumption: Reducing your alcohol intake helps prevent sudden drops in blood pressure and reduces the risk of excessive dizziness.
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Have a query?

How Soon It Starts Working

The time required for Nexovas O Tablet to start to work: The time required for Nexovas O Tablet to show its action is not clinically established. 

The time for which the effects of Nexovas O Tablet last: The duration of action for Nexovas O Tablet is not clinically established.

What if you forget to take Nexovas O Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Nexovas O Tablet tablets in their original packaging at room temperature, ideally below 30°C (86°F). Keep the container tightly closed to protect the medicine from moisture and direct light.

Drug Warnings

  • Get up slowly: To prevent dizziness or fainting, take your time when standing up from a sitting or lying position.
    Monitor your blood pressure: Keep a regular log of your blood pressure readings at home to share with your doctor at your next appointment.
  • Watch for severe diarrhoea: Contact your doctor immediately if you develop severe, ongoing watery diarrhoea, as one of the active ingredients can sometimes cause gut issues months after starting the medication.
  • Schedule regular blood tests: Your doctor will need to perform periodic blood tests to check your kidney function and potassium levels while you are on this medicine.
  • Avoid driving if dizzy: Do not drive, operate machinery, or perform dangerous tasks until you know how this medication affects your alertness.
     

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Nexovas O Tablet .

  • Potassium-sparing diuretics or potassium supplements: Taking these with Nexovas O Tablet may cause dangerously high levels of potassium in your blood.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen: Regular use of these pain relievers can reduce the blood pressure-lowering effect of Nexovas O Tablet and increase the risk of kidney damage.
  • Other blood pressure medications: Combining this with drugs like ACE inhibitors or aliskiren can increase the risk of excessively low blood pressure, high potassium, and reduced kidney function.
  • Lithium: Nexovas O Tablet may increase the levels of lithium in your blood, raising the risk of lithium toxicity.
     
Olmesartan medoxomil + CilnidipineAliskiren
Critical
Olmesartan medoxomil + CilnidipineFosinopril
Severe

Drug-Drug Interactions

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Olmesartan medoxomil + CilnidipineAliskiren
Critical
How does the drug interact with Nexovas O Tablet:
Using aliskiren together with Olmesartan medoxomil and Cilnidipinel may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Olmesartan medoxomil and Cilnidipinel with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience vomiting, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting a doctor.
Olmesartan medoxomil + CilnidipineFosinopril
Severe
How does the drug interact with Nexovas O Tablet:
Coadministration of Olmesartan medoxomil and Cilnidipinel with fosinopril may increase the risk of hyperkalemia (increase potassium levels in the blood).

How to manage the interaction:
Although taking Olmesartan medoxomil and Cilnidipinel together with fosinopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience vomiting, weakness, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomil + CilnidipineRamipril
Severe
How does the drug interact with Nexovas O Tablet:
Taking ramipril with Olmesartan medoxomil and Cilnidipinel may increase the risk of side effects (blood pressure, kidney function impairment, and a condition called Hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking Olmesartan medoxomil and Cilnidipinel with ramipril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience vomiting, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomil + CilnidipinePotassium chloride
Severe
How does the drug interact with Nexovas O Tablet:
Using Olmesartan medoxomil and Cilnidipinel with Potassium chloride may increase Potassium levels in the blood.

How to manage the interaction:
Although taking Olmesartan medoxomil and Cilnidipinel together with Potassium chloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience vomiting, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomil + CilnidipinePotassium citrate
Severe
How does the drug interact with Nexovas O Tablet:
Coadministration of Olmesartan medoxomil and Cilnidipinel may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmesartan medoxomil and Cilnidipinel together with potassium citrate may result in an interaction, they can be taken together if prescribed by a doctor. However, consult the doctor if you experience vomiting, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Olmesartan medoxomil + Cilnidipinepotassium phosphate
Severe
How does the drug interact with Nexovas O Tablet:
Using potassium phosphate together with Olmesartan medoxomil and Cilnidipinel may significantly increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmesartan medoxomil and Cilnidipinell with potassium phosphate together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience vomiting, a weak pulse, or a slow or irregular heartbeat, consult a doctor. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomil + CilnidipineLithium
Severe
How does the drug interact with Nexovas O Tablet:
Taking lithium with Olmesartan medoxomil and Cilnidipinel may significantly increase the blood levels of lithium .

How to manage the interaction:
Although taking Olmesartan medoxomil and Cilnidipinel alongside lithium can lead to interaction, they can be taken if prescribed by a doctor. However, if you develop dizziness, vomiting, blurred vision, ringing in the ears, or increased urination, consult a doctor. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomil + CilnidipineTrimethoprim
Severe
How does the drug interact with Nexovas O Tablet:
Taking Olmesartan medoxomil and Cilnidipinel with trimethoprim may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmesartan medoxomil and Cilnidipinel with trimethoprim may lead to an interaction it can be taken if prescribed by the doctor. However, consult the doctor if you experience vomiting, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomil + CilnidipineTriamterene
Severe
How does the drug interact with Nexovas O Tablet:
Taking Olmesartan medoxomil and Cilnidipinel with triamterene may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmesartan medoxomil and Cilnidipinel with triamterene may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience vomiting, tingling in hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomil + CilnidipinePotassium iodide
Severe
How does the drug interact with Nexovas O Tablet:
Coadministration of Olmesartan medoxomil and Cilnidipinel with potassium iodide may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmesartan medoxomil and Cilnidipinel together with potassium iodide may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience vomiting, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: Grapefruit can increase the amount of cilnidipine absorbed by your body, which may cause your blood pressure to drop too low.
  • Salt substitutes containing potassium: Using these can lead to high potassium levels in your blood
     
CILNIDIPINE-10MG+OLMESARTAN MEDOXOMIL-20MGPotassium rich foods
Moderate

Drug-Food Interactions

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CILNIDIPINE-10MG+OLMESARTAN MEDOXOMIL-20MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Coadministration of potassium-containing salt substitutes with Olmesartan medoxomil and Cilnidipine may cause high levels of potassium in blood. Avoid potassium-containing salt substitutes while being treated with Olmesartan medoxomil and Cilnidipine.

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

No, you should not take Nexovas O Tablet if you are pregnant or planning to become pregnant. It can cause serious harm or death to an unborn baby, especially if taken during the second and third trimesters. If you discover you are pregnant, stop taking this medicine immediately and talk to your doctor.
It is best to avoid or strictly limit alcohol while taking Nexovas O Tablet . Alcohol can cause a sudden, temporary drop in blood pressure, making you feel dizzy, lightheaded, or faint when standing up. Talk to your doctor or pharmacist about safe alcohol consumption.
Swelling in the lower legs and ankles (edema) is a known side effect of the calcium channel blocker component in Nexovas O Tablet , which relaxes and widens small blood vessels, occasionally causing fluid to pool in the lower extremities. If this swelling becomes uncomfortable or worsens, talk to your doctor.
Severe, chronic diarrhea with significant weight loss can occasionally develop months or even years after starting Nexovas O Tablet due to the olmesartan component. If you experience this, contact your doctor immediately, as you may need to switch to a different blood pressure medicine. Talk to your doctor.
Yes, feeling dizzy or lightheaded is a common side effect, especially when you first start taking Nexovas O Tablet or when your dose is increased. This usually improves as your body adjusts to the lower blood pressure. To prevent falling, rise slowly from sitting or lying down, and talk to your doctor if the dizziness persists.
Yes, your doctor will likely recommend periodic blood tests to monitor your kidney function and check the levels of electrolytes, particularly potassium, in your blood. This helps ensure that Nexovas O Tablet remains safe and effective for you over time. Talk to your doctor.
Nexovas O Tablet may cause weight gain in some people. This is because the medication can cause fluid retention, increased sodium levels, and increased appetite. However, weight gain is not a common side effect; it affects people differently. If you're worried about weight gain or notice significant changes, consult your doctor for guidance.
Nexovas O Tablet is unlikely to affect fertility or sex life in men or women. However, if you're having difficulty trying for a baby, it's recommended to speak with your doctor. They can provide guidance and address any concerns you may have.
Nexovas O Tablet contains olmesartan, medoxomil, and cilnidipine. Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Cilnidipine blocks the activities of the calcium channels present in the heart's blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body.
Common side effects of Nexovas O Tablet include headache, nausea, peripheral oedema (swelling of legs/hands), or dizziness in some cases. Most of these side effects of Nexovas O Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - NEX0153
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