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compositionComposition:ISOSORBIDE MONONITRATE-10MG
prescription
Prescription Medicine
info
Nitrofix 10 mg Tablet 10's

Nitrofix 10 mg Tablet is used to treat angina pectoris. It contains Isosorbide mononitrate, which relaxes the muscles of blood vessels, especially of the heart, leading to proper blood flow towards the heart muscle. It may cause common side effects such as nausea, dizziness, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ISOSORBIDE MONONITRATE-10MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nitrofix 10 mg Tablet

Nitrofix 10 mg Tablet is a prescription medicine used to prevent chest pain, which is also known as angina, in people with heart disease. It works by relaxing and widening your blood vessels, allowing blood and oxygen to flow more easily to your heart. It is important to know that this medicine is used to prevent chest pain attacks and will not stop a chest pain attack that has already started.

To get the most benefit, you must take Nitrofix 10 mg Tablet regularly every day at the same times as directed by your healthcare provider. You can take this tablet with or without food, but keeping a consistent routine is key to maintaining steady medicine levels in your body. Combining this medication with heart-healthy lifestyle choices, such as eating a low-salt diet and doing gentle, doctor-approved exercise, can improve your long-term results.

Headaches are a very common side effect when you first start taking this medicine, but they usually get better as your body adjusts to the treatment. However, if you experience severe dizziness, an unusually fast or slow heartbeat, or fainting, you should consult your doctor right away. Always discuss any persistent or bothersome symptoms with your healthcare team.

Before starting Nitrofix 10 mg Tablet , talk to your doctor if you have a history of low blood pressure, severe anaemia, or recently had a heart attack. Do not take this if you are using medications for erectile dysfunction or high blood pressure in the lungs, as this combination can cause a sudden and dangerous drop in blood pressure.

Drinking alcohol while taking Nitrofix 10 mg Tablet can make you feel extremely dizzy and cause your blood pressure to drop too low. If you are pregnant, planning to breastfeed, or are an older adult, you should consult your doctor to discuss whether this medicine is safe for your specific situation.

Uses of Nitrofix 10 mg Tablet

Nitrofix 10 mg Tablet is used to prevent angina. The detailed uses of Nitrofix 10 mg Tablet are as follows:

  • Chest pain prevention (angina): Nitrofix 10 mg Tablet is prescribed to prevent chest pain caused by heart disease by reducing the workload on your heart and improving blood flow.
     

Key Benefits

Nitrofix 10 mg Tablet helps manage chronic chest pain (angina) by improving blood flow to the heart and reducing the workload on the cardiovascular system. By supporting a steady supply of oxygen to the heart muscle, it helps improve comfort and maintain daily activity levels.

  • Helps Reduce the Frequency of Chest Pain: By relaxing and widening blood vessels, Nitrofix 10 mg Tablet helps improve blood flow to the heart, reducing the occurrence of angina episodes and supporting greater day-to-day comfort.
  • Supports Improved Physical Activity: With better oxygen delivery to the heart muscle, Nitrofix 10 mg Tablet may help increase exercise tolerance and make activities such as walking, climbing stairs, and routine physical tasks more manageable.
  • Provides Long-Term Heart Support: When taken regularly as prescribed, Nitrofix 10 mg Tablet helps manage chronic heart conditions and supports ongoing cardiovascular health. This can contribute to a more active lifestyle and improved overall quality of life.
     
Side effects of Nitrofix 10 mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Stay hydrated by drinking plenty of water.
  • Limit caffeine, nicotine, and alcohol.
  • Avoid processed foods, excess salt, and sugary drinks.
  • Manage stress through relaxation techniques.
  • Exercise regularly and maintain a healthy weight.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Nitrofix 10 mg Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Nitrofix 10 mg Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

How Nitrofix 10 mg Tablet Works

Nitrofix 10 mg Tablet contains isosorbide mononitrate, which belongs to a group of medicines called vasodilators, which relax and widen blood vessels. Inside your body, the medicine releases a natural substance called nitric oxide, which signals the muscles in your blood vessel walls to relax. When these blood vessels widen, blood flows much more smoothly, delivering vital oxygen to your heart muscle. This widening also makes it easier for your heart to pump blood to the rest of your body, which directly prevents the strain and oxygen shortage that trigger painful chest pressure.
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Alcohol

Unsafe

Do not drink alcohol. It could increase the effect of Nitrofix 10 mg Tablet and lower your blood pressure too much. If this happens, you may feel dizzy or faint.

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Pregnancy

Consult your doctor

If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

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Breast Feeding

Consult your doctor

If you are a breastfeeding mother, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

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Driving

Unsafe

Nitrofix 10 mg Tablet may cause headaches, blurred vision, dizziness, or tiredness. Make sure you are not affected before you drive or operate machinery.

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Liver

Consult your doctor

A patient is advised to take this drug only during a doctor's consultation as there have been reports of interactions between liver patients and Nitrofix 10 mg Tablet .

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Kidney

Consult your doctor

A patient is advised to take this drug only on doctor's consultation as there have been reports of interactions between Kidney patients and Nitrofix 10 mg Tablet .

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Children

Unsafe

It is not to be given to children unless prescribed by a doctor.

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Heart

Safe if prescribed

Nitrofix 10 mg Tablet can be used in heart patients if prescribed by the physician to reduce the risk of heart attack and angina. Please consult your physician if you have any concerns.

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Geriatrics

Safe if prescribed

Nitrofix 10 mg Tablet can be safely used in elderly patients if prescribed by the physician. Close monitoring of the patient is needed.

What if I have taken an overdose of Nitrofix 10 mg Tablet

If you suspect an overdose, seek immediate emergency medical attention or call your local poison control centre. Symptoms of an overdose may include a severe throbbing headache, confusion, fever, rapid heartbeat, severe dizziness, or fainting.

Diet & Lifestyle Advise

  • Stand up slowly: To minimise dizziness or the risk of fainting, take your time when rising from a sitting or lying position. Pause for a moment before standing completely.
  • Avoid alcohol: Do not drink alcohol, as it can worsen the blood-vessel-widening effects of Nitrofix 10 mg Tablet , causing your blood pressure to drop dangerously low.
  • Stay well-hydrated: Drink plenty of water throughout the day, unless your doctor has advised you to limit fluids due to a heart condition.
  • Eat a heart-healthy diet: Focus on a diet low in sodium and saturated fats, rich in vegetables, fruits, and lean proteins, to support your blood vessels and overall heart health.
     

Have a query?

How Soon It Starts Working

  • The time required for Nitrofix 10 mg Tablet to start to work: The time required for Nitrofix 10 mg Tablet to show its action is not clinically established.
  • The time for which the effects of Nitrofix 10 mg Tablet last: The duration of action for Nitrofix 10 mg Tablet is not clinically established.

What if you forget to take Nitrofix 10 mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular routine. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure what to do.

Storage

•Store Nitrofix 10 mg Tablet tablets at room temperature, between 68°F and 77°F (20°C to 25°C). •Keep the medication in its original container, tightly closed, to protect it from moisture and direct light

Drug Warnings

  • Not for sudden attacks: Do not take Nitrofix 10 mg Tablet to treat a sudden, active chest pain attack because it works too slowly. Always keep your fast-acting rescue medicine (like sublingual nitroglycerin) with you for emergency relief.
  • Do not take with erectile dysfunction medicines: Do not take medicines like sildenafil, tadalafil, or vardenafil while taking Nitrofix 10 mg Tablet . This combination can cause a life-threatening drop in blood pressure.
  • Do not stop taking suddenly: Stopping this medicine abruptly can cause your chest pain to return or get worse. Always talk to your doctor before stopping or changing how you take it.
  • Monitor your blood pressure: Check your blood pressure regularly at home as advised by your doctor, and report any unusually low readings.
  • Be cautious when driving: This medicine can cause dizziness, especially when you first start taking it or when gradually increasing your dose. Avoid driving or operating machinery until you know how the medicine affects you.
     

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions:

  • Erectile dysfunction medications: Combining Nitrofix 10 mg Tablet with drugs like sildenafil, tadalafil, or vardenafil can cause a severe, life-threatening drop in blood pressure.
  • Blood pressure-lowering medications: Taking this medicine with other drugs that lower blood pressure (such as beta-blockers, diuretics, or calcium channel blockers) can increase the risk of severe dizziness and fainting.

Drug-Food Interactions:

  • Alcohol: Consuming alcohol can cause your blood vessels to dilate further, leading to severe dizziness, lightheadedness, and a dangerous drop in blood pressure.

Drug-Disease Interactions:

  • Low blood pressure (hypotension): Nitrofix 10 mg Tablet can worsen low blood pressure, increasing the risk of fainting and falls.
  • Severe anaemia: This medicine can interfere with the way oxygen is carried in your blood, which may be harmful if you have severe anaemia.
  • Certain heart conditions: If you have specific heart conditions, such as hypertrophic cardiomyopathy, this medicine can worsen your symptoms. Talk to your doctor to see if this medicine is safe for your heart.
     
Isosorbide mononitrateTadalafil
Critical
Isosorbide mononitrateRiociguat
Critical

Drug-Drug Interactions

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Isosorbide mononitrateTadalafil
Critical
How does the drug interact with Nitrofix 10 mg Tablet:
Coadministration of Tadalafil with Nitrofix 10 mg Tablet can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Nitrofix 10 mg Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Isosorbide mononitrateRiociguat
Critical
How does the drug interact with Nitrofix 10 mg Tablet:
Taking Riociguat with Nitrofix 10 mg Tablet can cause low blood pressure.

How to manage the interaction:
Taking Nitrofix 10 mg Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide mononitrateDihydroergotamine
Severe
How does the drug interact with Nitrofix 10 mg Tablet:
Taking Nitrofix 10 mg Tablet together with dihydroergotamine can increase the effects of dihydroergotamine.

How to manage the interaction:
Although taking Nitrofix 10 mg Tablet and dihydroergotamine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience an irregular heartbeat, nausea, vomiting, weakness, or coldness, numbness, chest pain or pain in the hands, feet, arms, or legs. Do not discontinue any medications without consulting a doctor.
Isosorbide mononitrateSodium nitrite
Severe
How does the drug interact with Nitrofix 10 mg Tablet:
Taking Nitrofix 10 mg Tablet with sodium nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Nitrofix 10 mg Tablet and sodium nitrite together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide mononitrateTizanidine
Severe
How does the drug interact with Nitrofix 10 mg Tablet:
Taking Nitrofix 10 mg Tablet with tizanidine will have an additive effect and may lower blood pressure.

How to manage the interaction:
Although taking Nitrofix 10 mg Tablet and tizanidine together can possibly result in an interaction, but it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or pulse or heart rate changes. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIANGINALS]

FAQs

Nitrofix 10 mg Tablet is used for a heart condition called angina pectoris. It works by relaxing the blood vessels of the heart, reducing the stress‚ on the heart and making it easier to pump blood.
No drastic fall in blood pressure is seen, and it is never advised except for a few antihypertensives, that too only under doctor consultation.
No, ergot-based drugs have been found to have interaction with Nitrofix 10 mg Tablet ; thus, they are not advised.
It can induce throbbing headaches, reddening of the skin, chills along with sweating, nausea, vomiting, and quick heartbeat if you take more than the prescribed dose of Nitrofix 10 mg Tablet . Seek emergency treatment and seek urgent consultation with your doctor if you are taking more than the prescribed dosage of this drug.
Nitrofix 10 mg Tablet may cause side effects such as dizziness, fainting, headache, nausea, low blood pressure, and swelling of eyelids, face or lips. If these side effects persist or worsen, please consult your doctor.
Yes, Nitrofix 10 mg Tablet may affect the heart rate. Nitrofix 10 mg Tablet decreases blood pressure, which further causes a decrease in the heart rate (bradycardia). In some cases, it may also cause an increase in the heart rate (tachycardia). If you notice a change in your heart rate or feel unwell after taking Nitrofix 10 mg Tablet , consult your doctor.
Yes, Nitrofix 10 mg Tablet can lower blood pressure. Nitrofix 10 mg Tablet widens the blood vessels and decreases the resistance in them, resulting in lower blood pressure, which in turn decrease the heartbeat and can lead to angina. Thus, Nitrofix 10 mg Tablet should be avoided in people who already have low blood pressure. If you have any concerns, discuss with your doctor.
Yes, Nitrofix 10 mg Tablet comes in the form of dividable tablets. However, you should not break it in two halves unless advised by your doctor. Taking excess or less medicine can lead to side effects or decreased effectiveness. This can ultimately affect the course of treatment.
Nitrofix 10 mg Tablet contains Isosorbide mononitrate as its active ingredient.
Nitrofix 10 mg Tablet works by the formation of the free radical nitric oxide (NO) inside our body, which leads to the relaxation of muscles of blood vessels, especially of the heart, leading to proper blood flow towards the heart muscle, which has been working under immense pressure due to decreased blood flow to it. Thereby, it reduces the blood pressure and load on the heart.
No, Nitrofix 10 mg Tablet is a long-acting medicine designed only to prevent chest pain from happening. It does not work quickly enough to stop an active attack. Always use your quick-acting rescue medicine for sudden chest pain, and talk to your doctor if attacks occur frequently.
Headaches are a very common side effect because the medicine widens the blood vessels in your head. These headaches usually become less severe or stop completely after a few days to weeks of regular use. Talk to your doctor or pharmacist about safe ways to manage this symptom.
No, you should avoid alcohol while taking this medicine. Alcohol increases the blood-vessel-widening effects of the medication, which can lead to a severe drop in blood pressure, severe dizziness, and fainting. Talk to your doctor if you have questions about alcohol use.
No. Do not take sildenafil (Viagra) or other erectile dysfunction medicines such as tadalafil or vardenafil while taking Nitrofix 10 mg Tablet unless specifically advised by your doctor. Combining these medicines can cause a sudden, severe, and potentially life-threatening drop in blood pressure, leading to dizziness, fainting, heart attack, or other serious complications.
If you miss a dose of Nitrofix 10 mg Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose (or more than about 12 hours have passed, if advised by your doctor), skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a missed dose, as this may increase the risk of side effects. If you are unsure what to do, consult your doctor or pharmacist.
Yes, this medicine can cause your blood pressure to drop slightly when you stand up, making you feel dizzy or lightheaded. To prevent this, rise very slowly from a sitting or lying position. If you feel extremely dizzy or faint, talk to your doctor right away.
No. Do not stop taking Nitrofix 10 mg Tablet without consulting your doctor, even if you feel well or your chest pain has improved. Stopping the medicine suddenly may cause your angina to return or worsen. Your doctor will advise you if and when it is appropriate to reduce or stop treatment.

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Country of origin

India

Manufacturer/Marketer address

27, RACE COURSE ROAD, BANGALORE-560 001, INDIA
Other Info - NIT0012

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